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Emerging ro.e o. liquid bio.sy in rat sarco.a virus mutated metastatic co.o.ectal cancer:A case repo.t

Wo.ld Jo.rnal o. Gastro.ntestinal o.co.o.y 2024年第1期16卷 234-243页

作者： Jo.o.Gramaça Isabel Go.es Fernandes Caro.ina Trabulo.Jo.na Go.çalves Rita Gameiro.do. Santo. Adriano.baptista idília Pina Centro.Ho.pitalar barreiro.Mo.tijo Centro Hospitalar Barreiro MontijoSetúbalBarreiro 2830-003Portugal Medical o.co.o.y Unit Centro Hospitalar Barreiro MontijoSetúbalBarreiro 2830-003Portugal

baCKGRo.ND In patients with metastatic co.o.ectal cancer(mCRC),the treatment o.tio.s are limited and have been pro.ed to.be affected by rat sarco.a virus(RAS)mutatio.al *** RAS wild-type(wt)patients,the co.binatio. o. antiepidermal gro.th facto. recepto.(EGFR)mo.o.lo.al antibo.ies with chemo.herapy(CT)is mo.e effective than CT *** the o.her hand,RAS-mutated patients are no. eligible fo. treatment with anti-EGFR *** SUMMARY Eleven patients with initially RAS-mutated mCRC were fo.lo.ed fro. diagno.is to.May *** the time o. cell-free DNA determinatio.,five patients had undergo.e o.e CT line,five patients had undergo.e two.CT lines,and o.e patient had undergo.e three CT lines(all in co.binatio. with bevacizumab).At the seco.d and third treatment lines[seco.d line(2L),third line(3L)],patients with neo.RAS wt received a co.binatio. o. CT and *** neo.RAS wt patients treated with anti-EGFR,o.r findings indicated an increase in pro.ressio.-free survival fo. bo.h 2L and 3L(14.5 mo.P=0.119 and 3.9 mo.P=0.882,respectively).Regarding 2L o.erall survival,we registered a slight increase in neo.RAS wt patients treated with anti-EGFR(33.6 mo.vs 32.4 mo.P=0.385).At data cut-o.f,two.patients were still alive:A RAS-mutated patient undergo.ng 3L treatment and a neo.RAS wt patient who.received 2L treatment with anti-EGFR(o.go.ng).Co.CLUSIo. o.r case series demo.strated that mo.ito.ing RAS mutatio.s in mCRC by liquid bio.sy may pro.ide an additio.al treatment line fo. neo.RAS wt patients.

关键词： Metastatic co.o.ectal cancer Rat sarco.a virus mutatio.al status Liquid bio.sy Rat sarco.a virus wild-type Neo.rat sarco.a virus wild-type Anti-epidermal gro.th facto. recepto. therapy Case repo.t

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Analysis o. a passive ankle exo.keleto. fo. reductio. o. metabo.ic co.ts during walking

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Defence Techno.o.y（防务技术） 2024年第7期37卷 62-68页

作者： Luís Quinto.Pedro.Pinheiro.Sergio.B.Go.calves Ivo.Ro.pa Paula Simo.s Miguel Tavares da Silva CINAMIL Academia MilitarInstituto Universitario MilitarLisbonPortugal idMEC Instituto Superior TecnicoUniversidade de LisboaLisbonPortugal

Mo.ern co.flicts demand substantial physical and psycho.o.ical exertio.,o.ten resulting in fatigue and diminished co.bat o. o.eratio.al *** exo.keleto.s have been develo.ed recently to.address these challenges,presenting vario.s limitatio.s that affect their o.eratio.al o. everyday *** article evaluates the perfo.mance o. a dual-purpo.e passive ankle exo.keleto. develo.ed fo. the reductio. o. metabo.ic co.ts during walking,seeking to.identify a fo.ce element that co.ld be applied to.the target *** o. the 6-min walk test,twenty-nine subjects participated in the study using three different fo.ce *** results indicate that it is po.sible to.reduce metabo.ic expenditure while using the develo.ed ***,the co.fo.t and range o. mo.io. results verify the exo.keleto.'s suitability fo. use in uneven terrain and during extended ***,the cho.ce o. the fo.ce element sho.ld be tailo.ed to.each user,and the co.tro. system sho.ld be adjustable to.o.timise the exo.keleto.'s perfo.mance.

关键词： Ankle passive exo.keleto. Metabo.ic co.t reductio. Dual-use exo.keleto. Gait Bio.echanics

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Vine pruning waste-based activated carbo. fo. cerium and lanthanum adso.ptio. fro. water and real leachate

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Jo.rnal o. Rare Earths 2024年第10期42卷 1960-1968页

作者： Raphael Fo.gearini Pinheiro.Alejandro.Grimm Kátia da Bo.t Martinello.Mo.ammad Rizwan Khan Naushad Ahmad Luis Felipe o.iveira Silva Irineu Antônio.Schadach De Brum Guilherme Luiz Do.to.Glaydso. Simões do. Reis Research Gro.p o. Adso.ptive and Catalytic Pro.ess Engineering(ENGEPAC) Federal University of Santa MariaAv.Roraima1000-797105900Santa MariaRSBrazi Department o. Fo.est Bio.aterials and Techno.o.y Biomass Technology CentreSwedish University of Agricultural SciencesUmed SE-90183Sweden Universidad De La Co.ta Calle 58#55-66080002BarranquillaAtlanticoColombia Department o. Chemistry College of ScienceKing Saud UniversityRiyadh11451Kingdom of Saudi Arabia Institute o. Chemistry Federal University of Rio Grande do Sul90040-060Porto AlegreBrazil

In this study,vine pruning wastes(VPW)were used as raw material to.develo. an alternative activated carbo.(VPW-AC)fo. adso.bing and co.centrating rare earth elements cerium(Ce(Ⅲ))and lanthanum(La(Ⅲ))fro. synthetic and real leachate *** Ce and La adso.ptio. studies evaluated the effects o. VPW-AC do.age,pH,co.tact time,rare earth initial co.centratio.,and *** VPW-AC adso.bent was subjected to.many physico.hemical characterizatio. metho.s to.co.relate and understand its adso.ptive *** characterizatio. data indicate a carbo.aceo.s adso.bent with a specific surface area o. 467 m^(2)/*** po.ential indicates a material with a negatively charged surface at a pH higher than 3.1,which is extremely beneficial to.catio.s *** bo.h rare earths elements(REes),the adso.ptio. capacity increases with the increase o. the pH,reaching its maximum at pH *** kinetic data are well fitted by Avrami-fractio.al o.rder,while the Liu mo.el agreeably fits equilibrium *** maximum adso.ptio. capacities fo. Ce(Ⅲ)and La(Ⅲ)are 48.45 and 53.65 mg/g at 298 K,*** thermo.ynamic studies suggest that the adso.ptio. pro.ess is favo.able,spo.taneo.s,and exo.hermic fo. bo.h *** filling,surface co.plexatio.,and io. exchange are the do.inant ***,the VPW-AC was subjected to.the reco.ery o. REes fro. real pho.pho.ypsum leachate,and it is pro.ed that it can be successfully used to.reco.er REes in a real pro.ess.

关键词： Vine pruning wastes Sustainable carbo. adso.bent Rare earth elements Pho.pho.ypsum leachate Io.-exchange mechanism

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Efficient Peo.le Detectio. with Infrared Images

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Jo.rnal o. Co.puter and Co.municatio.s 2024年第4期12卷 31-39页

作者： Maria da Co.ceição.Pro.nça Marine and Enviro.mental Sciences Centre & ARNET Aquatic Research Infrastructure Network Associated Laboratory Department of Physics Faculty of Sciences University of Lisbon Lisbon Portugal

This wo.k fo.uses o. the pro.lem o. mo.ito.ing the co.stline, which in Po.tugal’s case means mo.ito.ing 3007 kilo.eters, including 1793 maritime bo.ders with the Atlantic o.ean to.the so.th and west. The human burden o. the co.st beco.es a pro.lem, bo.h because ero.io. makes the cliffs unstable and because po.lutio. increases, making the fragile dune eco.ystem difficult to.preserve. It is beco.ing necessary to.increase the co.tro. o. access to.beaches, even if it is no. a po.ular measure fo. internal and external to.rism. The metho.o.o.y described can also.be used to.mo.ito. maritime bo.ders. The use o. images acquired in the infrared range guarantees active surveillance bo.h day and night, the main o.jective being to.mimic the infrared cameras already installed in so.e critical areas alo.g the co.stline. Using a series o. infrared pho.o.raphs taken at lo. angles with a mo.ified camera and appro.riate filter, a recent deep learning algo.ithm with the right training can simultaneo.sly detect and co.nt who.e peo.le at clo.e range and peo.le almo.t co.pletely submerged in the water, including partially visible targets, achieving a perfo.mance with F1 sco.e o. 0.945, with 97% o. targets co.rectly identified. This implementatio. is po.sible with o.dinary lapto. co.puters and co.ld co.tribute to.mo.e frequent and mo.e extensive co.erage in beach/bo.der surveillance, using infrared cameras at regular intervals. It can be partially auto.ated to.send alerts to.the autho.ities and/o. the nearest lifeguards, thus increasing mo.ito.ing witho.t relying o. human reso.rces.

关键词： Beach o.erlo.d Peo.le Co.nting Bo.der Co.tro. Peo.le Detectio. Deep Learning Metho.s Remo.e Surveillance

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Study o. 6-Do. active vibratio.-iso.atio. system o. the ultra-precisio. turning lathe based o. GA-BP-Pid co.tro. fo. dynamic lo.ds

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Advances in Manufacturing 2024年第1期12卷 33-60页

作者： Bo.Wang Zho.g Jiang Pei-da Hu Department o. Precisio. Instrument Tsinghua UniversityBeijing100084People’s Republic of China Institute o. Machinery Manufacturing Techno.o.y China Academy of Engineering PhysicsMianyang621900SichuanPeople’s Republic of China

The vibratio. disturbance fro. an external enviro.ment affects the machining accuracy o. ultra-precisio. machining *** active vibratio.-iso.atio. systems(AVIS)have been develo.ed based o. static *** a vibratio.-iso.atio. lo.d changes dynamically during ultra-precisio. turning lathe machining,the system parameters change,and the efficiency o. the active vibratio.-iso.atio. system based o. the traditio.al co.tro. strategy *** so.ve this pro.lem,this paper pro.o.es a vibratio.-iso.atio. co.tro. strategy based o. a genetic algo.ithm-back pro.agatio. neural netwo.k-Pid co.tro.(GA-BP-Pid),which can auto.atically adjust the co.tro. parameters acco.ding to.the machining ***-iso.atio. simulatio.s and experiments based o. passive vibratio. iso.atio.,a Pid algo.ithm,and the GA-BP-Pid algo.ithm under dynamic lo.d machining co.ditio.s were *** experimental results demo.strated that the active vibratio.-iso.atio. co.tro. strategy designed in this study co.ld effectively attenuate vibratio. disturbances in the external enviro.ment under dynamic lo.d *** design is reaso.able and feasible.

关键词： Ultra-precisio. diamo.d turning lathe Active vibratio. iso.atio. Six degrees o. freedo. Dynamic lo.d Genetic algo.ithm-back pro.agatio. neural netwo.k-Pid(GA-BP-Pid)co.tro.

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Small-scale self-driving cars:A systematic literature review

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Jo.rnal o. Traffic and Transpo.tatio. Engineering(English Editio.) 2024年第2期11卷 271-292页

作者： Felipe Caleffi Lauren da Silva Ro.rigues Jo.ce da Silva Stambo.o.ki Brenda Medeiro. Pereira Auto.o.o.s Vehicles Labo.ato.y Federal University of Santa MariaCachoeira do Sul 96503-205Brazil Mo.ility and Lo.istics Labo.ato.y Federal University of Santa MariaCachoeira do Sul 96503-205Brazil

The auto.o.o.s vehicle(AV)techno.o.y has the po.ential to.significantly impro.e safety and efficiency o. the transpo.tatio. and lo.istics ***-scale AV testing is limited by time,space,and co.t,while simulatio.-based testing o.ten lacks the necessary accuracy o. AV and enviro.mental *** recent years,several initiatives have emerged to.test auto.o.o.s so.tware and hardware o. scaled *** systematic literature review pro.ides an o.erview o. the literature surro.nding small-scale self-driving cars,summarizing the current auto.o.o.s platfo.ms deplo.ed and fo.using o. the so.tware and hardware develo.ments in this *** studies published in English-language jo.rnals o. co.ference papers that present small-scale testing o. self-driving cars were *** o. Science,Sco.us,Springer Link,Wiley,ACM Digital Library,and TRid databa.es were used fo. the literature *** systematic literature search fo.nd 38 eligible *** gaps in the reviewed papers were identified to.pro.ide guidance fo. future *** key takeaway emerging fro. this manuscript are:(i)there is a need to.impro.e the mo.els and neural netwo.k architectures used in auto.o.o.s driving systems,as mo.t papers present o.ly preliminary results;(ii)increasing datasets and sharing databa.es can help in develo.ing mo.e reliable co.tro. po.icies and reducing bias and variance in the training pro.ess;(iii)small-scaled vehicles to.ensure safety is a majo. benefit,and inco.po.ating data abo.t unsafe driving behavio.s and infrastructure pro.lems can impro.e the accuracy o. predictive mo.els.

关键词： Self-driving car Auto.o.o.s vehicle Small-scale vehicle Systematic literature review

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o. the glo.al smo.th so.utio.s o. 3D inco.pressible Hall-MHD equatio.s

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Applied Mathematics(A Jo.rnal o. Chinese Universities) 2024年第2期39卷 319-327页

作者： YUE Gao.cheng SUN Wen-da Scho.l o. Mathematics Nanjing University of Aeronautics and AstronauticsNanjing 211106China

The present paper is devo.ed to.the well-po.edness issue fo. the 3D inco.pressible Hall-MHD system o.tained fro. kinetic mo.els. o.r analysis stro.gly relies o. the use o. the Fo.rier analysis. We establish the glo.al existence o. smo.th so.utio.s fo. a class o. large initial data, this result implies the initial velo.ity and magnetic field can be arbitrarily large.

关键词： 3D Hall-MHD well-po.edness Fo.rier analysis

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o. entire so.utio.s o. so.e Fermat type differential-difference equatio.s

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Applied Mathematics(A Jo.rnal o. Chinese Universities) 2024年第1期39卷 69-88页

作者： Lo.G Jian-ren QIN da-zhuan Scho.l o. Mathematical Sciences Guizhou Normal UniversityGuiyang 550025China

o. o.e hand,we study the existence o. transcendental entire so.utio.s with finite o.der o. the Fermat type difference *** the o.her hand,we also.investigate the existence and gro.th o. so.utio.s o. no.linear different... 详细信息

关键词： entire so.utio.s differential-difference equatio.s existence finite o.der

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Quantized bo.nd states aro.nd a vo.tex in aniso.ro.ic superco.ducto.s

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Science China(Physics,Mechanics & Astro.o.y) 2024年第6期67卷 146-155页

作者： Ke Xiang da Wang Qiang-Hua Wang Natio.al Labo.ato.y o. So.id State Micro.tructures&Scho.l o. Physics Nanjing UniversityNanjing 210093China Co.labo.ative Inno.atio. Center o. Advanced Micro.tructures Nanjing 210093China

The bo.nd states aro.nd a vo.tex in aniso.ro.ic superco.ducto.s is a lo.gstanding yet impo.tant *** this wo.k,we develo. a variatio.al theo.y o. the basis o. the Andreev appro.imatio. to.o.tain the energy levels and wave functio.s o. the lo.-energy quantized bo.nd states in superco.ducto.s with aniso.ro.ic pairing o. arbitrary Fermi *** the case o. circular Fermi surface,the effective Schr¨o.inger equatio. yielding the bo.nd state energies gets back to.the theo.y pro.o.ed by Vo.o.ik and Ko.nin many years *** generalizatio. here enables us to.pro.e the equidistant energy spectrum inside a vo.tex in a bro.der class o. *** impo.tantly,we are no. able to.o.tain the wave functio.s o. these bo.nd states by pro.ecting the quasiclassical wave functio. o. the eigenmo.es o. the effective Schr¨o.inger equatio.,go.ng beyo.d the quasiclassical Eilenberger results,which,as we find,are sensitive to.the scattering *** the case o. iso.ro.ic Fermi surface,the spatial pro.ile o. the lo.-energy lo.al density o. states is do.inated near the vo.tex center and elo.gates alo.g the gap antino.e directio.s,in additio. to.the ubiquito.s Friedel o.cillatio. arising fro. the quantum inteference neglected in the Eilenberger ***,as a co.sequence o. the pairing aniso.ro.y,the quantized wave functio.s develo. a peculiar distributio. o. winding number,which reduces stepwise to.ards the vo.tex *** wo.k pro.ides a flexible way to.study the vo.tex bo.nd states in the future.

关键词： vo.tex bo.nd state aniso.ro.ic superco.ducto. Andreev appro.imatio.

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Drago.fly Interactio. Algo.ithm fo. o.timizatio. o. Queuing Delay in Industrial Wireless Netwo.ks

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Jo.rnal o. Bio.ic Engineering 2024年第1期21卷 447-485页

作者： Sanjay Bhardwaj da-Hye Kim Do.g-Seo.g Kim Department o. IT Co.vergence Engineering ICT Convergence Research CenterKumoh National Institute of TechnologyGumiSouth Korea

In industrial wireless netwo.ks,data transmitted fro. so.rce to.destinatio. are highly *** o.ten leads to.the queuing o. the data,and po.r management o. the queued data results in excessive delays,increased energy co.sumptio.,and packet ***,a nature-inspired-based Drago.fly Interactio. o.timizatio. Algo.ithm(DMo.)is pro.o.ed fo. o.timizatio. o. the queue delay in industrial wireless *** term“interactio.”herein used is the characterizatio. o. the“flying mo.ement”o. the drago.fly to.ards damselflies(female drago.flies)fo. *** a result,interactio. is represented as the flo. o. transmitted data packets,o. traffic,fro. the so.rce to.the base *** includes each and every feature o. drago.fly mo.ement as well as awareness o. the rival drago.flies,predato.s,and damselflies fo. the desired o.timizatio. o. the queue *** features are juxtapo.ed as no.se and interference,which are further used in the calculatio. o. industrial wireless metrics:latency,erro. rate(reliability),thro.ghput,energy efficiency,and fairness fo. the o.timizatio. o. the queue *** analysis,co.vergence analysis,the Wilco.o. test,the Friedman test,and the classical as well as the 2014 IEEE Co.gress o. Evo.utio.ary Co.putatio.(CEC)o. the benchmark functio.s are also.used fo. the evaluatio. o. DMo. in terms o. its ro.ustness and *** results demo.strate the ro.ustness o. the pro.o.ed algo.ithm fo. bo.h classical and benchmarking functio.s o. the IEEE CEC ***,the accuracy and efficacy o. DMo. were demo.strated by means o. the co.vergence rate,Wilco.o. testing,and ***,fairness using Jain’s index in queue delay o.timizatio. in terms o. thro.ghput and latency,alo.g with co.putatio.al co.plexity,is also.evaluated and co.pared with o.her *** results sho. that DMo. exceeds o.her bio.inspired o.timizatio. algo.ithms in terms o. fairness in queue delay management and average packet *** pro.o.ed a

关键词： Drago.fly damselfly Interactio. Queuing delay o.timizatio. Industrial wireless netwo.ks

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