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Chinese Journal of Polymer Science 2021年第6期39卷 692-701,I0005页

作者： Xiang Zhang da-wei jiang Guo-Liang Yang Yu-Cheng Zhu Jia Tian Hong-Liang Cao Yun Gao wei-An Zhang Shanghai Key Laboratory of Functional Materials Chemistry East China University of Science and TechnologyShanghai 200237China

Phototherapies including photodynamic therapy(PDT)and photothermal therapy(PTT)are the most promising and non-invasive cancer ***,the efficacy of mono-therapy of PDT or PTT is often limited by the phototherapeutic defects such as low light penetration depth of photosensitizers and insufficiency of photothermal ***(ONOO−)has been proved to be an efficient oxidizing and nitrating agent that involves in various physiological and pathological ***,ONOO−produced in tumor site could be an effective treatment in cancer ***,a novel cyanine dye-based(Cy7)polymer nanoplatform is developed for enhanced phototherapy by in situ producing ONOO−.The Cy7 units in the nanoparticles can not only be served as the photosensitizer to produce reactive oxygen species(ROS)including singlet oxygen and superoxide anion for PDT,but also be used as a heat source for PTT and the release of NO gas from N-nitrosated napthalimide(NORM)at the same *** NO can react quickly with superoxide anion to generate ONOO−,the enhanced phototherapy could be achieved by in situ ONOO−produced by PCy7-NO upon exposure to the near infrared(NIR)***,the NIR-triggered Cy7-based nanoplatform for ONOO−-enhanced phototherapy may provide a new perspective in cancer therapy.

关键词： Peroxynitrite(ONOO^(-)) Phototherapy Cyanine Napthalimide Near-infrared

A New Series of Mo-free 21.5Cr-3.5Ni-xW-0.2N Economical Duplex Stainless Steels

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Journal of Iron and Steel Research International 2014年第1期21卷 69-75页

作者： Zi-xing ZHANG Qing-xuan RAN Yu-lai XU Xiao-jiang YU da-wei jiang Xue-shan XIAO Laboratory for Microstructures Institute of MaterialsShanghai University

A new series of economical Mo-free duplex stainless steels 21.5Cr-3.5Ni-xW-0. 2N （x = 1.8 -- 3. 0, mass%） have been developed. The effects of W on mechanical properties and corrosion resistance were investigated, and the microstructures were analyzed by optical microscopy, X-ray diffraction, transmission electron microscopy and electron backscatter diffraction. The designed steels have a balanced ferrite-austenite relation and are free of sigma phase after solution treatment at 750--1 300 ~C for 30 min followed by water-quenching, whereas a small number of Cr23 C~ precipitates were found after solution treatment at 750 ~C. After solution treatment at 1050 ℃, the steel with 1.8~ （mass percent） W exhibits the highest room temperature tensile strength due to the strongest work hardening effect, while the steel with 3.0% （mass percent） W exhibits the highest fracture elongation owing to the transformation-in- duced plasticity （TRIP） effect. The ductile-brittle transition （DBT） and martensite transformation are respectively found in the ferrite and austenite, which deteriorates the impact properties of the steels with the increase of W con- tent. The corrosion resistance of the designed steels is improved with the increase of W content. The pitting resistance of austenite is obviously better than that of ferrite for the designed alloys. Among the designed steels, the steel with 1.8% （mass percent） W is found to be an optimum steel with excellent comprehensive properties and lowest production cost.

关键词： economical duplex stainless steel tungsten mechanical property pitting corrosion resistance

Synthesis and Characterization of a New Titanium-silicate Material Containing Cage-like Polyhedral Oligosilsesquioxane

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Chemical Research in Chinese Universities 2007年第4期23卷 388-390页

作者： DING Han-ming ZHANG da-wei LI jiang KONG Ai-guo SHAN Yong-kui Department of Chemistry East China Normal University Shanghai 200062 P. R. China

A new titanium-silicate material was synthesized with cubic cage-like tetramethylammonium octasilicate and TiCl4 ethanol solution as precursors. The product was characterized by FTIR, ^29Si NMR, UV-Vis, and XRD. Struc-tural and ingrediental analyses suggest that this material has a layered structure with cubic cage-like polyhedral oligo-silsesquioxane as building blocks and titanium as bridging atoms.

关键词： Polyhedral oligosilsesquioxane Synthesis Titanium-silicate material

Construction of Recombinant Fowlpox Virus(rFpv) Expressing HIV-1 Gag-pol Protein

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Chemical Research in Chinese Universities 2007年第1期23卷 64-68页

作者： TENG Hong-gang LUE Shuai-ran LIU da-wei jiang Chun-lai ZHANG Xi-zhen YU Xiang-hui KONG wei Vaccine Research Center College of Life Science Jilin University Changchun 130012 P. R. China

The induction of human immunodeficiency virus（HIV）-specific T-cell response is generally considered as critical to the development of effective immunity to HIV type 1 （ HIV-1 ）. Recombinant Avipoxvirus vectors are used widely for vaccination against HIV-1, where the induction of a cytotoxic CD8 ＋ T-cell（CTL） response seems to be an important component of protective immunity. A recombinant fowlpox virus（rFPV/Gag-pol） expressing the Gag-pol protein of HIV was constructed and characterized. The specific expression protein in CEF cells infected by recombinant fowlpox and the specific antibody in the sera of mice immunized with rFPV were analyzed via Western-blot.

关键词： HIV Gag-pol Recombinant fowlpox virus rFPV

FAM53B promotes pancreatic ductal adenocarcinoma metastasis by regulating macrophage M2 polarization

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1479-1499页

作者： Xuan-Zeng Pei Min Cai da-wei jiang Song-Hai Chen Qing-Qing Wang Hui-Min Lu Yi-Fan Lu Department of Hepatological Surgery The First Hospital of JiaxingJiaxing 314000Zhejiang ProvinceChina Department of General Surgery West China Hospital of Sichuan UniversityChengdu 610044Sichuan ProvinceChina

BACKGROUND Our study investigated the role of FAM53B in regulating macrophage M2 polarization and its potential mechanisms in promoting pancreatic ductal adenocarcinoma(PdaC)*** To further investigate the role of FAM53B in regulating macrophage M2 polarization and its potential mechanism in promoting PdaC *** goal is to determine how FAM53B affects macrophage M2 polarization and to define its underlying mechanism in PdaC *** Cell culture and various experiments,including protein analysis,immunohisto-chemistry,and animal model experiments,were *** compared FAM53B expression between PdaC tissues and healthy tissues and assessed the correlation of FAM53B expression with clinical *** study analyzed the role of FAM53B in macrophage M2 polarization in vitro by examining the expression of relevant ***,we used a murine model to study the role of FAM53B in PdaC metastasis and analyzed the potential underlying *** Our research showed that there was a significant increase in FAM53B levels in PdaC tissues,which was linked to adverse tumor *** findings indicated that FAM53B can enhance macrophage M2 polarization,leading to increased anti-inflammatory factor *** results from the mouse model further supported the role of FAM53B in PdaC metastasis,as blocking FAM53B prevented tumor cell invasion and *** FAM53B promotes PdaC metastasis by regulating macrophage M2 *** discovery could lead to the development of new strategies for treating *** example,interfering with the FAM53B signaling pathway may prevent cancer *** research findings also provide important information for expanding our understanding of PdaC pathogenesis.

关键词： FAM53B Pancreatic ductal adenocarcinoma Tumor metastasis Macrophage polarization

Complex integrity constraint discovery: measuring trust in modern intelligent railroad systems

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2022年第10期23卷 832-837页

作者： Wen-tao HU da-wei jiang Sai WU Ke CHEN Gang CHEN Key Lab of Intelligent Computing Based Big data of Zhejiang Province Zhejiang UniversityHangzhou 310027China

1Introduction data are at the heart of intelligent rail systems in the high-speed transportation sector(Zhou et al.,2020;Ho et al.,2021;Hu et al.,2021;Chen et al.,2022).The core of modern intelligent railroad systems typically includes rail transportation and equipment monitoring models learned from large datasets,which are often optimized for specific data and workloads(Zhu et al.,2019;Tan et al.,2020).While these intelligent railroad systems have been widely adopted and successful,their reliability and proper function will change as the data used *** the data used(on which the system operates)deviates from the fundamental constraints of the initial data(on which the system is trained)then,in that case,the system performance degrades,and the results inferred by the system model become unreliable,so the system model must be retrained and redeployed to re-store reliable inference results(Sharma and Chandel,2013).The mechanism for assessing the trustworthiness of intelligent rail system inferences is of paramount importance,especially for rail systems performing safety-critical or high-impact operations.

关键词： constraint intelligent operations

Application of Internet plus education in medical technical training

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TMR Theory and Hypothesis 2020年第1期3卷 285-289页

作者： Jian Zhu da-wei jiang Yun Wu Hunan Aerospace Hospital Hunan410205China Centre for Health Law Research Central South UniversityHunan410083China

With the rapid development of Internet technology,the mode of medical education is constantly changing,and the training mode of traditional medical technology gradually reveals its *** on that,the staff combined the Internet technology and medical education,formed the"Internet+education"model,as the main way of medical technology training,so as to optimize the medical education system,improve the level of medical education,improve the interactive,real-time,science and technology and modernity of medical education,and further promote the construction and development of medical education in *** article analyzes the application theory of the previous"Internet+education"in medical technology training,and proposes a set of theories that can supplement the lack of traditional medical technology training and education in order to integrate"Internet+education"in medical technology training To maximize the role of the role of China,and put forward their own hypotheses and ideas for future development.

关键词： Internet+education Medical technology Training

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中华民族共同体建设与人类文明新形态

中南民族大学学报（人文社会科学版） 2023年第3期43卷 36-45,182页

作者：魏大江华中师范大学马克思主义学院湖北武汉430079

生产力与生产关系的内在矛盾构成了文明形态变革的内在动力。资本逻辑的文明形态将民族国家形塑为现代化主体力量,创造出空前的物质力量与人类的“世界历史”,却因“物的依赖关系”无法形成“真正的共同体”。中华民族共同体建设,本质... 详细信息

生产力与生产关系的内在矛盾构成了文明形态变革的内在动力。资本逻辑的文明形态将民族国家形塑为现代化主体力量,创造出空前的物质力量与人类的“世界历史”,却因“物的依赖关系”无法形成“真正的共同体”。中华民族共同体建设,本质上是要超越西方民族国家建构的现代性之困,探索人类文明新形态。中华民族共同体建设,不能跳过或取消中华民族的政治社会建设阶段,要从中华文明大一统历史观、共同历史记忆、共有精神家园谱系中寻找建设新文明形态的资源,从中华文明可长可久之道、比较发展优势以及引领人类文明发展模式中确证人类文明新形态,并以新文明执政党品格、新文明知识体系、社会主义文明之治来增强中华民族共同体建设的自觉。

关键词：中华民族共同体人类文明文明建设文明自觉

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基于多任务委托代理模型的导游激励问题研究

运筹与管理 2017年第2期26卷 158-164页

作者：李大伟张江华山东大学历史文化学院文化产业管理系山东济南250100 山东大学管理学院信息管理系山东济南250100

运用多任务委托代理模型研究导游最优激励合同后得出,当小费、回扣为旅行社带来直接收益的情况时,在激励相容条件下,导游引导游览活动的最优激励合同是其绝对风险规避度、边际激励成本变化率和可观测变量方差的递减函数;导游赢得小费活... 详细信息

运用多任务委托代理模型研究导游最优激励合同后得出,当小费、回扣为旅行社带来直接收益的情况时,在激励相容条件下,导游引导游览活动的最优激励合同是其绝对风险规避度、边际激励成本变化率和可观测变量方差的递减函数;导游赢得小费活动的最优激励合同为"临界型激励合同",即只有当导游所创造的收益超过某临界值,对其的激励才是正向的,若小于该临界值,激励将是负向的;导游获取回扣活动的最优激励合同只与其完成回扣任务的业绩有关;当小费和回扣不为旅行社带来直接收益的情况时,那么在激励相容条件下,导游在小费和回扣活动上的努力依赖于激励报酬,而且导游的最优激励合同与其在小费和回扣活动上的收益无关。

关键词：旅游管理导游人员激励多任务委托代理模型

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鲁棒的基于几何均值分解的矢量预编码算法

上海交通大学学报 2011年第7期45卷 1046-1049页

作者：武大伟何晨蒋铃鸽上海交通大学电子信息与电气工程学院上海200240

针对非理想信道的多输入多输出(MIMO)系统,提出了一种鲁棒的基于几何均值分解方法的矢量预编码算法.利用非理想信道误差矩阵的二阶统计信息,以最小化收发信号的均方误差为准则,求出基于几何均值分解矢量预编码的最优扰动矢量和预编码矩... 详细信息

针对非理想信道的多输入多输出(MIMO)系统,提出了一种鲁棒的基于几何均值分解方法的矢量预编码算法.利用非理想信道误差矩阵的二阶统计信息,以最小化收发信号的均方误差为准则,求出基于几何均值分解矢量预编码的最优扰动矢量和预编码矩阵.仿真结果表明,该鲁棒算法优于现有的基于几何均值分解矢量预编码算法性能.在高信噪比时,误码率可提高2dB以上.

关键词：多输入多输出非理想信道状态信息几何均值分解矢量预编码