检索结果-南通市图书馆

Food Science and Human Wellness 2024年

作者： Zong-Qi Zhang Si-Cong Chen Qing-Lei Wang Chun-Qin Liu Jin-Hua Xiao da-wei huang College of Life Sciences Nankai University Hebei Key Laboratory of Soil Entomology Cangzhou Academy of Agricultural and Forestry Sciences

Due to the rapid development of obesity and related metabolic diseases in the world， it is particularly important to explore the ability of novel materials in regulating obesity. In this study， C57BL/6J obese mice were used as objects， and 16S rRNA gene sequencing and lipidomics techniques were used to explore the regulatory effect and mechanism of the P. brevitarsis ethanol extract (50%， v/v) against obesity. Our results showed that P. brevitarsis extract could significantly reduce the body weight， triglyceride (TG)， total cholesterol (TC)， low-density lipoprotein cholesterol (LDL-C)， and pro-inflammatory cytokines (TNF-α， IFN-γ， and IL-6) levels of HFD-fed mice. Moreover， the P. brevitarsis extract changed the composition and relative abundance of its gut microbiota， especially increasing Akkermansia muciniphila. Meanwhile， the content of short-chain fatty acids (SCFAs) was increased， especially acetic acid and butyric acid， which leads to a decrease in the synthesis and accumulation of lipids in the liver. Furthermore， the P. brevitarsis extract also induced the difference in lipid synthesis in the liver by down-regulating the mRNA levels of SREPB-1C， FAS， and ACC. Therefore， this research provided preliminary work and reference for the development of P. brevitarsis as a functional food for anti-obesity.

关键词：

Complicated expansion trajectories of insertion sequences and potential association with horizontal transfer of Wolbachia DNA

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Zoological Research 2023年第2期44卷 273-275页

作者： Yun-Heng Miao da-wei huang Jin-Hua Xiao College of Life Sciences Nankai UniversityTianjin 300071China

DEAR EDITOR,Insertion sequences(ISs) are the simplest structural transposable elements(TEs) in prokaryotes, consisting only of a transposase coding sequence and its bilateral short terminal inverted repeats. Due to their gradually streamlined genomic construction, TEs rarely exist in the genomes of obligate endosymbionts. However, TE content, especially ISs.

关键词： sequences insertion Wolbachia

Evolutionary timescale of chalcidoid wasps inferred from over one hundred mitochondrial genomes

在线全文

学校读者我要写书评

暂无评论

Zoological Research 2023年第3期44卷 467-482页

作者： Jia-Chen Zhu Hui Xiao Pu Tang Xiao-Fei Li Xuan-Kun Li Chao-Dong Zhu Qiong Wu Jin-Hua Xiao Cornelis van Achterberg da-wei huang Xue-Xin Chen State Key Laboratory of Rice Biology Ministry of Agriculture and Rural Affairs Key Lab of Molecular Biology of Crop Pathogens and Insect PestsProvincial Key Lab of Biology of Crop Pathogens and Insect Pests of ZhejiangInstitute of Insect SciencesZhejiang UniversityHangzhouZhejiang 310058China Key Laboratory of Zoological Systematics and Evolution Institute of ZoologyChinese Academy of SciencesBeijing 100101China Florida Museum of Natural History University of FloridaGainesvilleFL 32611 USA College of Life Sciences Nankai UniversityTianjin 300071China

Chalcidoidea is one of the most biologically diverse groups among Hymenoptera.Members are characterized by extraordinary parasitic lifestyles and extensive host ranges,among which several species attack plants or serve as pollinators.However,higher-level chalcidoid relationships remain controversial.Here,we performed mitochondrial phylogenomic analyses for major clades(18out of 25 families)of Chalcidoidea based on 139 mitochondrial genomes.The compositional heterogeneity and conflicting backbone relationships in Chalcidoidea were assessed using various datasets and tree inferences.Our phylogenetic results supported the monophyly of 16families and polyphyly of Aphelinidae and Pteromalidae.Our preferred topology recovered the relationship(Mymaridae+(Signiphoridae+Leucospidae)+(Chalcididae+((Perilampidae+Eucharitidae)+remaining Chalcidoidea))).The monophyly of Agaonidae and Sycophaginae was rejected,while the gall-associated((Megastigmidae+Ormyridae)+(Ormocerinae+Eurytomidae))relationship was supported in most results.A six-gene inversion may be a synapomorphy for most families,whereas other derived gene orders may introduce confusion in phylogenetic signals at deeper nodes.dating estimates suggested that Chalcidoidea arose near the Jurassic/Cretaceous boundary and that two dynamic shifts in diversification occurred during the evolution of Chalcidoidea.We hypothesized that the potential codiversification between chalcidoids and their hosts may be crucial for accelerating the diversification of Chalcidoidea.Ancestral state reconstruction analyses supported the hypothesis that gallinducers were mainly derived from parasitoids of gallinducers,while other gall-inducers were derived from phytophagous groups.Taken together,these findings advance our understanding of mitochondrial genome evolution in the major interfamilial phylogeny of Chalcidoidea.

关键词： Mitochondrial genome Chalcidoidea Compositional heterogeneity Divergence time Evolution of host and gall associations

Pollinating fig wasp Ceratosolen solmsi adjusts the offspring sex ratio to other foundresses

在线全文

学校读者我要写书评

暂无评论

Insect Science 2013年第2期20卷 228-234页

作者： Hao-Yuan Hu Zhong-Zheng Chen Zi-Feng Jiang da-wei huang Li-Ming Niu Yue-Guan Fu Key Laboratory of Biotic Environment and Ecological Safety in Anhui Province College of Life Sciences Anhui Normal University Wuhu Anhui Province China Department of Biology University of Maryland College Park Maryland USA Key Laboratory of Zoological Systematics and Evolution Institute of Zoology Chinese Academy of Sciences Beijing China Plant Protection College Shandong Agricultural University Tai'an Shandong Province China Environment and Plant Protection Institute Chinese Academy of Tropical Agricultural Sciences Danzhou Hainan Province China

Local mate competition theory predicts that offspring sex ratio in pollinating fig wasps is female-biased when there is only one foundress, and increased foundress density results in increased offspring sex ratio. Information of other foundresses and clutch size have been suggested to be the main proximate explanations for sex ratio adjustment under local mate competition. Our focus was to show the mechanism of sex ratio adjustment in a pollinating fig wasp, Ceratosolen solmsi Mayr, an obligate pollinator of the functionally dioecious fig, Ficus hispida Linn., with controlled experiments in the field. First, we obtained offspring from one pollinator and offspring at different oviposition sequences, and found that offspring sex ratio decreased with clutch size, and pollinators produced most of their male offspring at the start of bouts, followed by mostly females. Second, we found that offspring sex ratio increased with foundress density, and pollinators did adjust their offspring sex ratio to other females in the oviposition patches. We suggest that when oviposition sites are not limited, pollinators will mainly adjust their offspring sex ratio to other foundresses independent of clutch size changes, whereas adjusting clutch size may be used to adjust sex ratio when oviposition sites are limited.

关键词： behavior co-evolution local mate competition mutualism pollinating figwasp sex ratio adjustment

Effect of laser shock peening on combined low- and high-cycle fatigue life of casting and forging turbine blades

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research(International) 2018年第1期25卷 108-119页

作者： Cao Chen Xiao-yong Zhang Xiao-jun Yan Jun Ren da-wei huang Ming-jing Qi School of Energy and Power Engineering BeihangUniversity Beijing 100191 China Collaborative Innovation Center of Advanced Aero-Engine Beijing 100191 China National Key Laboratory of Science and Technologyon Aero-Engine Aero-Thermodynamics Beijing 100191China Beijing Key Laboratory of Aero-Engine Structureand Strength Beijing 100191 China

Laser shock peening （LSP） is a novel effective surface treatment method to improve the fatigue performance of turbine blades. To study the effect of LSP on combined low- and high-cycle fatigue （CCF） life of turbine blades, the CCF tests were conducted at elevated temperatures on two types of full-scale turbine blades, which were made of K403 by casting and GH4133B by forging. Probabilistic analysis was conducted to find out the effect of LSP on fatigue life of those two kinds of blades. The results indicated that LSP extended the CCF life of both casting blades and forging blades obviously, and the effect of LSP on casting blades was more evident; besides, a threshold vibration stress existed for both casting blades and forging blades, and the CCF life tended to be extended by LSP only when the vibration stress was below the threshold vibra- tion stress. Further study of fractography was also conducted, indicating that due to the presence of compressive residual stress and refined grains induced by LSP, the crack initiation sources in LSP blades were obviously less, and the life of LSP blades was also longer; since the compressive residual stress was released by plastic deformation, LSP had no effect or adverse effect on CCF life of blade when the vibration stress of blade was above the threshold vibration stress.

关键词： Laser shock peening Combined low-and high-cycle fatigue life （CCF） Full-scale turbine blade S-N curve -Threshold vibration stress

High incidences and similar patterns of Wolbachia infection in fig wasp communities from three different continents

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insect Science 2010年第2期17卷 101-111页

作者： Lin-Lin Chen James M. Cook Hui Xiao Hao-Yuan Hu Li-Ming Niu da-wei huang Key Laboratory of Zoological Systematics and Evolution Institute of Zoology Chinese Academy of Sciences Beijing China Graduate University of Chinese Academy of Sciences Beijing China School of Biological Sciences University of Reading Reading UK College of Plant Protection Shandong Agricultural University Tai'an Shandong Province China

Wolbachia are endosymbiotic bacteria that infect numerous arthropod species. Previous studies in Panama and Australia revealed that the majority of fig wasp species harbor Wolbachia infections, but that similar patterns of incidence have evolved inde- pendently with different wasp species and Wolbachia strains on the two continents. We found Wolbachia infections in 25/47 species （53%） of fig wasp associated with 25 species of Chinese figs. Phylogenetic analyses of Wotbachia wsp sequences indicated that very similar strains are not obviously found in either closely related or ecologically linked fig wasps species. The extremely high prevalence of Wolbachia in fig wasps （over 50% of species infected） is not constrained by geographical origin and is a recurrent theme of fig wasp/Wolbachia interactions.

关键词： fig wasps horizontal transmission Wolbachia wsp

Isolation of microsatellite loci in the pollinating fig wasp of Ficus hispida, Ceratosolen solmsi

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insect Science 2008年第4期15卷 303-306页

作者： Hao Yu Tong-Xin Zhang Hao-Yuan Hu Li-Ming Niu Hui Xiao Yan-Zhou Zhang da-wei huang Institute of Zoology Chinese Academy of Sciences Beijing Graduate School of the Chinese Academy of Sciences Beijing Plant Protection College Shandong Agricultural University Tai' an Shandong China

Microsatellite loci were isolated for Ceratosolen solmsi, pollinator of the dioecious Ficus hispida. We developed nine polymorphic microsatellite loci based on the method of polymerase chain reaction isolation of microsatellite arrays （PIMA）. Enrichment of genomic libraries was performed by random amplified polymorphic DNA （RAPD）. A subset of 38 positive clones was sequenced; 15 clones showed microsatellite loci. We tested 15 designed primer pairs and nine of them produced polymorphic amplification in 48 individual wasps collected from different fruits of the dioecious host fig Ficus hispida in China. Among the 48 individuals, 49 alleles were obtained at the nine loci. The observed heterozygosity ranged between 0.357 and 0.634.

关键词： Ficus fig wasp markers microsatellite loci polymorphism primers

Visible light-driven oxidation of non-native substrate by laccase attached on Ru-based metal-organic frameworks

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2024年第3期137卷 741-753页

作者： Wenguang huang Wentao Zhang Guantongyi Chen Yun Chen Jun Ma dawei huang Qinzheng Zhaoc Bingdang Wu State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment South China Institute of Environmental SciencesMinistry of Ecology and Environment of PRCGuangzhou 510655China Tsinghua Shenzhen International Graduate School Tsinghua UniversityShenzhen 518055China School of Environmental Science and Engineering Suzhou University of Science and TechnologySuzhou 215002China Key Laboratory of Suzhou Sponge City Technology Suzhou 215002China

Light-induced electron transfer can broaden the substrate range of metalloenzyme.However,the efficiency of photo-enzyme coupling is limited by the poor combination of photosensitizer or photocatalyst with enzyme.Herein,we prepared the nano-photocatalyst MIL-125-NH_(2)@Ru(bpy)by in site embedding ruthenium pyridine-diimine complex[Ru(bpy)_(3)^(2+)into metal organic frameworks MIL-125-NH_(2)and associated it with multicopper oxidase(MCO)laccase.Compared to[Ru(bpy)_(3)]^(2+),the coupling efficiency of MIL-125-NH_(2)@Ru(bpy)_(3)for enzymatic oxygen reduction increased by 35.7%.A series of characterizations confirmed that the amino group of laccase formed chemical bonds with the surface defects or hydrophobic groups of MIL-125-NH_(2)@Ru(bpy)_(3).Consequently,the tight binding accelerated the quenching process and electron transfer between laccase and the immobilized ruthenium pyridine-diimine complex.This work would open an avenue for the synthesis of MOFs photocatalyst towards photo-enzyme coupling.

关键词： Laccase Light-driven biocatalysis Ruthenium photocatalyst Metal-organic frameworks Enzyme immobilization

Malvidin Mitigates Sepsis-induced Cardiac Injury by Modulating the TLR4-iNOS-COX-2 Inflammatory Pathway and the Bax/Bcl-2/Cyto-C Mitochondrial Apoptosis Pathway in a p38 MAPK-dependent Manner

在线全文

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2024年第2期37卷 221-227页

作者： ZHANG wei YUAN Si Long QIANG Jing Chao huang He LI da SUN Ying ZHANG Hong Gang Department of Vascular Surgery The First People’s Hospital of LianyungangLianyungang 222005JiangsuChina Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening College of PharmacyJiangsu Ocean UniversityLianyungang 222005JiangsuChina Jinzhou Medical University postgraduate training base(Lianyungang First People’s Hospital) Lianyungang 222005JiangsuChina

In critical care medicine,sepsis is a dangerous systemic condition that is highly prevalent and is associated with high morbidity and mortality rates^([1]).The high mortality rate associated with sepsis is closely related to multi-organ dysfunction,with heart injury being particularly critical and considered the starting point of multi-organ injury^([2]).

关键词： mortality Apoptosis TLR4

LonP1 Links Mitochondria–ER Interaction to Regulate Heart Function

在线全文

学校读者我要写书评

暂无评论

Research 2024年第1期2023卷 595-609页

作者： Yujie Li dawei huang Lianqun Jia Fugen Shangguan Shiwei Gong Linhua Lan Zhiyin Song Juan Xu Chaojun Yan Tongke Chen Yin Tan Yongzhang Liu Xingxu huang Carolyn K.Suzuki Zhongzhou Yang Guanlin Yang Bin Lu The Affiliated Nanhua Hospital and School of Basic Medical Sciences Hengyang Medical SchoolUniversity of South ChinaHengyangHunan 421001China School of Laboratory Medicine and Life Sciences Wenzhou Medical UniversityWenzhouZhejiang 325035China National Health Commission Key Laboratory of Birth Defect Research and Prevention Hunan Provincial Maternal and Child Health Care HospitalChangshaHunan 410008China Key Laboratory of Ministry of Education for TCM Viscera-State Theory and Applications Ministry of Education of ChinaLiaoning University of Traditional Chinese MedicineShenyangLiaoning 110847China Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiangChina Hubei Key Laboratory of Cell Homeostasis College of Life SciencesWuhan UniversityWuhanHubei 430072China Nanjing Maternity and Child Health Care Hospital Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical UniversityNanjing 210004China Animal Center Wenzhou Medical UniversityWenzhouZhejiang 325035China Department of Cardiology The First Affiliated Hospital of University of South ChinaHengyangHunanChina School of Life Science and Technology Shanghai Tech UniversityShanghai 201210China Department of Microbiology Biochemistry and Molecular GeneticsNew Jersey Medical School-RutgersThe State University of New JerseyNewarkNJUSA State Key Laboratory of Pharmaceutical Biotechnology Department of CardiologyNanjing Drum Tower HospitalThe Affiliated Hospital of Nanjing University Medical School and MOE Key Laboratory of Model Animal for Disease StudyModel Animal Research CenterNanjing UniversityNanjing 210061China

Interorganelle contacts and communications are increasingly recognized to play a vital role in cellular function and homeostasis.In particular,the mitochondria–endoplasmic reticulum(ER)membrane contact site(MAM)is known to regulate ion and lipid transfer,as well as signaling and organelle dynamics.However,the regulatory mechanisms of MAM formation and their function are still elusive.Here,we identify mitochondrial Lon protease(LonP1),a highly conserved mitochondrial matrix protease,as a new MAM tethering protein.The removal of LonP1 substantially reduces MAM formation and causes mitochondrial fragmentation.Furthermore,deletion of LonP1 in the cardiomyocytes of mouse heart impairs MAM integrity and mitochondrial fusion and activates the unfolded protein response within the ER(UPR^(ER)).Consequently,cardiac-specific LonP1 deficiency causes aberrant metabolic reprogramming and pathological heart remodeling.These findings demonstrate that LonP1 is a novel MAM-localized protein orchestrating MAM integrity,mitochondrial dynamics,and UPR^(ER),offering exciting new insights into the potential therapeutic strategy for heart failure.

关键词： offering programming insight