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Distribution of pathogenic bacteria and antimicrobial sensitivity of eye infections in Suzhou

International Journal of Ophthalmology(English edition) 2024年第4期17卷 700-706页

作者： Li Zhang Hai-Zhang you Guo-Hui Wang Wei xu Jian-Shan Li Qing-Liang Zhao Shu Du Department of Hospital-Acquired Infection Control Lixiang Eye Hospital of Soochow UniversitySuzhou 215021Jiangsu ProvinceChina Department of Administrative Office Lixiang Eye Hospital of Soochow UniversitySuzhou 215021Jiangsu ProvinceChina Department of Clinical Laboratory Lixiang Eye Hospital of Soochow UniversitySuzhou 215021Jiangsu ProvinceChina Department of Pharmacy Lixiang Eye Hospital of Soochow UniversitySuzhou 215021Jiangsu ProvinceChina Department of Corneal and Lacrimal Passage Lixiang Eye Hospital of Soochow UniversitySuzhou 215021Jiangsu ProvinceChina Department of Fundus Diseases and Ocular Trauma Lixiang Eye Hospital of Soochow UniversitySuzhou 215021Jiangsu ProvinceChina

AIM:To investigate the types of bacteria in patients with eye infections in Suzhou and their drug resistance to commonly used antibacterial ***:The clinical data of 155 patients were retrospectively collected in this study,and the pathogenic bacteria species and drug resistance of each pathogenic bacteria were ***:Among the 155 patients(age from 12 to 87 years old,with an average age of 57,99 males and 56 females)with eye infections(160 eyes:74 in the left eye,76 in the right eye and 5 in both eyes,all of which were exogenous),71(45.81%)strains were gram-positive bacteria,23(14.84%)strains were gram-negative bacteria and 61(39.35%)strains were ***-positive bacteria were highly resistant to penicillin and erythromycin(78.87%and 46.48%respectively),but least resistant to vancomycin at ***-negative bacteria were highly resistant to cefoxitin and compound sulfamethoxazole(100%and 95.65%respectively),but least resistant to meropenem at *** of the resistance of gram-positive and gram-negative bacteria to some drugs revealed statistically significant differences(P<0.05)in the resistance of both to cefoxitin,cotrimoxazole,levofloxacin,cefuroxime,ceftriaxone and ceftazidime,and both had higher rates of resistance to gram-negative bacteria than to gram-positive *** distribution of bacterial infection strains showed that Staphylococcus epidermidis was the most common strain in the conjunctiva,cornea,aqueous humor or vitreous body and other eye ***,Fusarium and Pseudomonas aeruginosa were also among the most common strains of conjunctival and corneal ***:Gram-positive bacteria are the dominant bacteria in eye infections,followed by gram-negative bacteria and *** the resistance of gramnegative bacteria to multiple drugs,monitoring of bacteria should be strengthened in eye bacterial infections for effective prevention and control to reduce complications caused by eye infections.

关键词： eye infection pathogenic bacteria drug resistance antimicrobial sensitivity test

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High-performance sodium storage for cobalt phosphide composite array electrodes

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Rare Metals 2024年第8期43卷 3724-3734页

作者： Man Zhang Xiao-xu Liu Tian-Yi Ji Yang Li da-Wei Sheng Shao-Dong Li Pei-Pei Ren Ze-Xiang Shen School of Material Science and Engineering Shaanxi University of Science and TechnologyXi'an 710021China School of Physical and Mathematical Sciences Nanyang Technological UniversitySingapore 637371Singapore

Transition metal phosphides hold great potential as sodium-ion batteries anode materials owing to their high theoretical capacity and modest ***,volume changes and low intrinsic conductivity seriously largely hinder the further development of metal phosphide *** design of phosphide anode materials with reasonable structure is conducive to solving the problems of volume expansion and slow reaction kinetics during the *** this work,a composite material integrating zeolite imidazolate backbone(ZIF) and carbon materials was synthesized by the original growth ***,by the oxidation-phosphating process,CoP nanoarray composites riveted to carbon fiber(CoP@CF) were *** the CoP@CF,CoP nanoparticles are uniformly distributed on ZIF-derived carbon,reducing agglomeration and volume change during *** also provides a highly conductive network for the active material,improving the electrode ***,when evaluated as an anode for sodium-ion batteries,CoP@CF electrode displays enhanced reversible capacity(262 mAh·g^(-1) at 0.1 A·g^(-1)after 100 cycles),which is much better than that of pure CF electrode(57 mAh·g^(-1) at 0.1 A·g^(-1) after 100 cycles)prepared without the addition of *** rate performance of CoP@CF electrode is also superior to that of pure CF electrode at various current densities from 0.05 to1 A·g^(-1).The sodium storage behavior of CoP@CF was revealed by ex-situ X-ray photoelectron spectroscopy,X-ray diffraction,and synchrotron radiation absorption *** method provides a reference for the design and synthesis of anode materials in sodium-ion batteries.

关键词： Cobalt phosphide Array structure Freestanding anodes Sodium-ion batteries

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Associations Between Air Temperature and daily Varicella Cases—Jinan City,Shandong Province,China,2019–2021

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China CDC weekly 2024年第2期6卷 36-39,I0008,I0009页

作者： Guijie Luan Yuehua Hu Meng Chen Meiying you Chengdong xu dapeng Yin Jianjun Liu Hongyan Yao Chinese Center for Disease Control and Prevention BeijingChina Institute for Immunization management Shandong Center forDisease Control and PreventionJinan CityShandong ProvinceChina State Key Laboratory of Resources and Environmental Information System Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of SciencesBeijingChina Hainan Provincial Center for Disease Control and Prevention Haikou CityHainan ProvinceChina.

What is already known about this topic?The impact of air temperature on varicella has been studied,but there is limited research exploring its effect on varicella by gender and age *** is added by this report?We conducted a time series analysis to examine the differential effects of air temperature on varicella infection across different demographic *** findings indicate that lower temperatures have a more pronounced influence on varicella incidence among males and children compared to females and *** are the implications for public health practice?These findings can assist in identifying populations that are vulnerable to temperature-related varicella and in guiding the implementation of effective measures for varicella control.

关键词： finding measures Shandong

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Multi-omics analysis of adamantinomatous craniopharyngiomas reveals distinct molecular subgroups with prognostic and treatment response significance

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Chinese Medical Journal 2024年第7期137卷 859-870页

作者： Xianlong Wang Chuan Zhao Jincheng Lin Hongxing Liu Qiuhong Zeng Huadong Chen Ye Wang dapeng xu Wen Chen Moping xu En Zhang da Lin Zhixiong Lin Department of Bioinformatics School of Medical Technology and EngineeringKey Laboratory of Medical BioinformaticsKey Laboratory of Ministry of Education for Gastrointestinal CancerFujian Medical UniversityFuzhouFujian 350122China Department of Neurosurgery Sanbo Brain HospitalCapital Medical UniversityBeijing 100093China

Background:Adamantinomatous craniopharyngioma(ACP)is the commonest pediatric sellar *** effective drug is available and interpatient heterogeneity is *** study aimed to identify distinct molecular subgroups of ACP based on the multi-omics profiles,imaging findings,and histological features,in order to predict the response to anti-inflammatory treatment and ***:Totally 142 Chinese cases diagnosed with craniopharyngiomas were profiled,including 119 ACPs and 23 papillary ***-exome sequencing(151 tumors,including recurrent ones),RNA sequencing(84 tumors),and DNA methylome profiling(95 tumors)were *** clustering and non-negative matrix factorization were used for subgrouping,and Cox regression were utilized for prognostic evaluation,***:Three distinct molecular subgroups were identified:WNT,ImA,and *** WNT subgroup showed higher Wnt/β-catenin pathway activity,with a greater number of epithelial cells and more predominantly solid *** ImA and ImB subgroups had activated inflammatory and interferon response pathways,with enhanced immune cell infiltration and more predominantly cystic ***-activated protein kinases(MEK/MAPK)signaling was activated only in ImA samples,while IL-6 and epithelial-mesenchymal transition biomarkers were highly expressed in the ImB group,mostly consisting of *** degree of astrogliosis was significantly elevated in the ImA group,with severe finger-like protrusions at the invasive front of the *** molecular subgrouping was an independent prognostic factor,with the WNT group having longer event-free survival than ImB(Cox,P=0.04).ImA/ImB cases were more likely to respond to immune checkpoint blockade(ICB)therapy than the WNT group(P<0.01).In the preliminary screening of subtyping markers,CD38 was significantly downregulated in WNT compared with ImA and ImB(P=0.01).Conclusions:ACP comprises three molecular subtypes with distinct

关键词： Craniopharyngioma Central nervous system tumor Precision medicine beta Catenin Proto-Oncogene Proteins B-raf

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The genesis and resource potential of gold deposits in the Liaodong Peninsula

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Science China Earth Sciences 2024年第3期67卷 657-672页

作者： Rixiang ZHU Jin-Hui YANG Gongwen WANG Qingdong ZENG Guoqiang xuE Tao xu Xinghui LI Peng ZHANG da LEI Guang ZHU State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China School of Earth Sciences and Resources China University of GeosciencesBeijing 100083China Shenyang Center China Geological SurveyShenyang 110034China School of Resources and Environmental Engineering Hefei University of TechnologyHefei 230009China

Plenty of gold deposits related to Late Mesozoic craton destruction are widely distributed in eastern North China Craton. However, significant differences in research degrees, ore-forming characteristics, and proven reserves exist among different regions in the North China Craton. The Liaodong Peninsula has similar regional geological characteristics to those of the Jiaodong Peninsula, with both experiencing craton destruction during Late Mesozoic, but the two areas have substantial differences in terms of gold mineralization and the proven gold resources. Based on regional geology, Mesozoic magmatictectonic evolution and ore geology, combined with integrated geophysical exploration and big data AI resource prediction, in this paper, we propose that the ore-forming materials of Late Mesozoic gold deposits in Liaodong were mainly originated from mantle-derived melts and/or fluids induced by craton destruction. The gold deposits were primarily controlled by NE-NNEtrending faults, mainly classified as fracture-controlled altered rock-type and sulfide-bearing quartz vein-type. Moreover, our study predicts that the Yalu River fault zone and its related secondary faults, as well as the periphery and deeper parts of known goldfields, are the important regions for future gold resource exploration. The Yalu River metallogenic belt has an enormous potential for gold resources, and the Liaodong Peninsula has a potential to add thousands of tons of gold resources.

关键词： Liaodong Peninsula Gold deposit Integrated geophysical exploration Prospecting potential Direction for prospecting breakthroughs

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Hyperbolic hierarchical graph attention network for knowledge graph completion

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High Technology Letters 2024年第3期30卷 271-279页

作者： xu Hao CHEN Shudong QI Donglin TONG da YU Yong CHEN Shuai Institute of Microelectronics of Chinese Academy of Sciences Beijing 100029P.R.China University of Chinese Academy of Sciences Beijing 100049P.R.China

Utilizing graph neural networks for knowledge embedding to accomplish the task of knowledge graph completion(KGC)has become an important research area in knowledge graph ***,the number of nodes in the knowledge graph increases exponentially with the depth of the tree,whereas the distances of nodes in Euclidean space are second-order polynomial distances,whereby knowledge embedding using graph neural networks in Euclidean space will not represent the distances between nodes *** paper introduces a novel approach called hyperbolic hierarchical graph attention network(H2GAT)to rectify this ***,the paper conducts knowledge representation in the hyperbolic space,effectively mitigating the issue of exponential growth of nodes with tree depth and consequent information ***,it introduces a hierarchical graph atten-tion mechanism specifically designed for the hyperbolic space,allowing for enhanced capture of the network structure inherent in the knowledge ***,the efficacy of the proposed H2GAT model is evaluated on benchmark datasets,namely WN18RR and FB15K-237,thereby validating its *** H2GAT model achieved 0.445,0.515,and 0.586 in the Hits@1,Hits@3 and Hits@10 metrics respectively on the WN18RR dataset and 0.243,0.367 and 0.518 on the FB15K-237 *** incorporating hyperbolic space embedding and hierarchical graph attention,the H2GAT model successfully addresses the limitations of existing hyperbolic knowledge embedding models,exhibiting its competence in knowledge graph completion tasks.

关键词： hyperbolic space link prediction knowledge graph embedding knowledge graph completion(KGC)

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Enhancing the crystallinity and stability of perovskite solar cells with 4-tert-butylpyridine induction for efficiency exceeding 24%

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Journal of Energy Chemistry 2024年第6期93卷 1-7,I0001页

作者： you Liu Lishuang Zheng Kuanxiang Zhang Kun xu Weicheng Xie Jue Zhang Yulu Tian Tianyuan Liu Hanzhong xu Ruoming Ma Wei Huang Jiahui Chen Jusheng Bao Chen Chen Yongsheng Zhou xuchun Wang Junming Chen Jungan Wang College of Chemistry and Materials Engineering Anhui Science and Technology UniversityBengbu 233000AnhuiChina Anhui Province Quartz Sand Purification and Photovoltaic Glass Engineering Research Center Chuzhou 233100AnhuiChina Triumph Photovoltaic Materials Co.Ltd BengbuAnhuiChina National Laboratory of Solid State Microstructures School of PhysicsNanjing UniversityNanjing 210009JiangsuChina JinkoSolar Holding Co.Ltd HainingZhejiangChina

Perovskite solar cells(PSCs)have emerged as a promising photovoltaic technology because of their high light absorption coefficient,long carrier diffusion distance,and tunable ***,PSCs face challenges such as hysteresis effects and stability *** this study,we introduced a novel approach to improve film crystallization by leveraging 4-tert-butylpyridine(TBP)molecules,thereby enhancing the performance and stability of *** findings demonstrate the effective removal of PbI_(2)from the perovskite surface through strong coordination with TBP ***,by carefully adjusting the concentration of the TBP solution,we achieved enhanced film crystallinity without disrupting the perovskite *** TBP-treated perovskite films exhibit a low defect density,improved crystallinity,and improved carrier *** a result,the PSCs manufactured with TBP treatment achieve power conversion efficiency(PCE)exceeding 24%.Moreover,we obtained the PCE of 21.39%for the 12.25 cm^(2)module.

关键词： 4-tert-butylpyridine Film crystallization Perovskite solar cells Power conversion efficiency Stability improvement

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Sporophytic control of tapetal development and pollen fertility by a mitogen-activated protein kinase cascade in rice

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Journal of Integrative Plant Biology 2024年第7期66卷 1500-1516页

作者： Jianguo Zeng Manman Duan Yiqing Wang Guangtao Li Yujing you Jie Shi Changhao Liu Jinyang Zhang Juan xu Shuqun Zhang Jing Zhao Department of Plant Pathology Nanjing Agricultural UniversityNanjing 210095China State Key Laboratory of Plant Physiology and Biochemistry College of Life SciencesZhejiang UniversityHangzhou 310058China Division of Biochemistry University of MissouriColumbia65211MOUSA

Tapetum,the innermost layer of the anther wall,provides essential nutrients and materials for pollen *** degradation of anther tapetal cells is a prerequisite for normal pollen development in flowering *** cells facilitate male gametogenesis by providing cellular contents after highly coordinated programmed cell death(PCD).Tapetal development is regulated by a transcriptional ***,the signaling pathway(s)involved in this process are poorly *** this study,we report that a mitogen-activated protein kinase(MAPK)cascade composed of OsYda1/OsYda2-OsMKK4-OsMPK6 plays an important role in tapetal development and male gametophyte *** of function of this MAPK cascade leads to anther indehiscence,enlarged tapetum,and aborted pollen *** cells in osmkk4 and osmpk6 mutants exhibit an increased presence of lipid body-like structures within the cytoplasm,which is accompanied by a delayed occurrence of *** of a constitutively active version of OsMPK6(CA-OsMPK6)can rescue the pollen defects in osmkk4 mutants,confirming that OsMPK6 functions downstream of OsMKK4 in this *** crosses also demonstrated that the MAPK cascade sporophyticly regulates pollen *** study reveals a novel function of rice MAPK cascade in plant male reproductive biology.

关键词： degradation MAPK cascade pollen fertility rice tapetum

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A monolithic integrated medium wave Mercury Cadmium Telluride polarimetric focal plane array

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JOURNAL OF INFRARED AND MILLIMETER WAVES 2024年第4期43卷 479-489页

作者： Chen, Ze-Ji Huang, you-Wen Pu, En-Xiang Xiao, Hui-Shan xu, Shi-Chun Qin, Qiang Kong, Jin-Cheng Kunming Inst Phys Infrared Detector Ctr Kunming 650223 Peoples R China

A medium wave (MW) 640x512 (25 mu m) Mercury Cadmium Telluride (HgCdTe) polarimetric focal plane array (FPA) was demonstrated. The micro-polarizer array (MPA) has been carefully designed in terms of line grating structure optimization and crosstalk suppression. A monolithic fabrication process with low damage was explored, which was verified to be compatible well with HgCdTe devices. After monolithic integration of MPA, NETD youts were designed, and the crosstalk was experimentally validated as the major source that impacted ER. By expanding opaque regions at pixel edges to 4 mu m, crosstalk rates from adjacent pixels could be effectively reduced to approximately 2%, and promising ERs ranging from 17. 32 to 27. 41 were implemented.

关键词： infrared physics infrared polarimetric focal plane array monolithic integration Mercury Cadmium Telluride extinction ratio PERFORMANCE DESIGN

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Combined ATAC-seq, RNA-seq, and GWAS analysis reveals glycogen metabolism regulatory network in Jinjiang oyster (Crassostrea ariakensis)

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动物学研究 2024年第1期

作者： Biao Wu Xi Chen Jie Hu Zhen-Yuan Wang Yan Wang da-you xu Hao-Bing Guo Chang-Wei Shao Li-Qing Zhou Xiu-Jun Sun Tao Yu Xiao-Mei Wang Yan-Xin Zheng Guang-Yi Fan Zhi-Hong Liu

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