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Strengthening the Disciplinary Construction of History of Medicine: A Call for Action by Chinese Academy of Medical Sciences & Peking Union Medical College

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Chinese Medical Sciences Journal 2023年第2期38卷 94-96页

作者： Jian-Hong Yao da-qing zhang Xin-Zhong Yu Shu-Jian zhang Yong-An zhang Xiang-Yin Yang Zhong He Huan Liu Yong Wang Yue-Ying Jin School of Medical Humanities and Social Sciences Peking Union Medical College&Chinese Academy of Medical SciencesBejing 100730China School of Medical Humanities Peking UniversityBejing 100191China Faculty of History Nankai UniversityTianjin 300072China institute of Chinese Medical Literature and Culture Shandong University of Traditional Chinese MedicineJinan250355China College of Liberal Arts Shanghai UniversityShanghai 200444China School of History Renmin University of ChinaBeijing 100086China

Recent years have witnessed a dynamic develop of Peking Union Medical College(PUMC),which was founded in 1921,and Chinese Academy of Medical Sciences(CAMS),which was founded in *** the new era of building a"Healthy China",General Secretary Xi Jinping has emphasized the importance of a profound understanding of the Chinese civilization to let the world better know and understand China,and urged efforts to combine theories and practices to expound how to better uphold the Chinese path,promote the Chinese spirit,and pool together the Chinese strength[1].As an active response,PUMC organized the first Conference of History of Medicine on May 20-21,2023[2],Based on the rich history of PUMC and with an attempt to explore history,inherit the traditional Chinese culture,and promote the spirit of modern medicine,we issued the following call at the conference。

关键词： History combine Peking

Robust Adaptive H∞ Fault-Tolerant Control for Uncertain Linear Systems against Actuator Failures

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Robust Adaptive H∞ Fault-Tolerant Control for Uncertain Lin...

Robust Fault Tolerant Control for Interconnected Systems With Dynamic Uncertainties and Actuator Faults

第26届中国控制与决策会议

作者： Li-Bing Wu Zhi-Guo zhang da-qing zhang Gui-Zhi Li The College of Sciences University of Science and Technology Liaoning

This paper is concerned with the robust adaptive H∞ fault-tolerant control problem for linear systems with the mismatched parameter uncertainties, input channel and external disturbances, and actuator faults including loss of effectiveness, outage and stuck. Without requiring any fault detection and isolation mechanism, a novel adaptation law with a rather simpler structure is employed to estimate the unknown controller parameters. Based on a notion of an adaptive H∞ performance index, the designed adaptive fault-tolerant controller can guarantee the disturbance attenuation and optimal H∞ performance. Furthermore, on the basis of Lyapunov stability theory, it is shown that the proposed fault-tolerant strategy guarantees that the closed-loop system is asymptotically stable in the presence of the mismatched parameter uncertainty, disturbance and actuator faults simultaneously. Finally, a rocket fairing structural-acoustic model is used to demonstrate the efficiency of the proposed fault-tolerant design approach.

关键词： Fault-tolerant control robust H∞ control mismatched parameter uncertainty indirect adaptive control asymptotically stable

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Robust Fault Tolerant Control for Interconnected Systems Wit...

Robust Adaptive Output Feedback Fault Tolerant Control for a Class of Nonlinear Systems With Faults and Disturbances

第30届中国控制与决策会议

作者： Sheng-Juan Huang da-qing zhang Liang-Dong Guo Li-Bing Wu The authors are with the School of Sciences University of Science and Technology Liaoning

This paper mainly focuses on the problem of robust fault tolerant control for a class of interconnected systems with simultaneous state uncertainties and actuator faults. An algorithm based on the iteration estimation technique is proposed, by which the fault estimates are able to be renewed and close to the fault values. Then, based on the online fault estimates, a robust fault tolerant controller via a robust approximate/adaptive dynamic programming（ADP）approach is designed to stabilize the interconnected system. Simulation results of a numerical example is presented to show the effectiveness and merits of the proposed method.

关键词： Fault-tolerant control(FTC) Approximate/adaptive dynamic programming(ADP) Interconnected systems Fault estimation

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Robust Adaptive Output Feedback Fault Tolerant Control for a...

Effect of pyrite content on chalcopyrite flotation under different regrinding conditions

第37届中国控制会议

作者： Sheng-Juan Huang da-qing zhang Liang-Dong Guo Li-Bing Wu the School of Sciences University of Science and Technology Liaoning

This paper is concentrated on the problem of robust adaptive output feedback fault tolerant control for a class of nonlinear systems with Lipschitzian nonlinearities and faults. An adaptive fault estimator and a nonlinearity approximator via the measured output signals is introduced to establish an output feedback fault tolerant controller, so that the designed controller parameters are able to be updated on-line to compensate the fault effect on the nonlinear systems. The proposed control strategy guarantees the asymptotic stability of the closed-loop system with a prescribed H∞ performance. Numerical examples demonstrate the effectiveness of the proposed control scheme.

关键词： Nonlinear systems output feedback fault tolerant control adaptive fault estimator nonlinearity approximator

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 49-57页

作者： Zejun Wang qing Shi Guofan zhang Yuxuan Zhu Binbin Li School of Minerals Processing and Bioengineering Central South UniversityChangsha 410083China Key Laboratory of Hunan Province for Clean and Efficient Utilization of Strategic Calcium-containing Mineral Resources Central South UniversityChangsha 410083China

This study aimed to investigate the effect of varying pyrite(Py)content on copper(Cu)in the presence of different regrinding conditions,which were altered using different types of grinding media:iron,ceramic balls,and their mixture,followed by flotation in the cleaner *** flotation performance of rough Cu concentrate can be improved by changing the regrinding conditions based on the Py *** electron microscopy,X-ray spectrometry,ethylenediaminetetraacetic acid disodium salt extraction,and X-ray photoelectron spectroscopy studies illustrated that when the Py content was high,the use of iron media in regrinding promoted the generation of hydrophilic Fe OOH on the surface of Py and improved the Cu *** ceramic medium with a low Py content prevented excessive Fe OOH from covering the surface of chalcopyrite(Cpy).Electrochemical studies further showed that the galvanic corrosion current of Cpy-Py increased with the addition of Py and became stronger with the participation of iron media.

关键词： chalcopyrite regrinding media pyrite galvanic corrosion flotation

Lactobacillus plantarum LY-78芳香族氨基酸转氨酶基因的克隆及序列分析

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中国生物制品学杂志 2017年第6期30卷 587-591,595页

作者：李芬孙大庆张丽萍黑龙江八一农垦大学食品学院黑龙江大庆163319 国家杂粮工程技术研究中心黑龙江大庆163319

目的克隆Lactobacillus plantarum LY-78芳香族氨基酸转氨酶基因arat,并对其基因序列进行生物信息学分析。方法利用PCR技术克隆得到芳香族氨基酸转氨酶基因arat的完整序列,测序后运用生物信息学软件预测arat基因对应蛋白的理化性质和结... 详细信息

目的克隆Lactobacillus plantarum LY-78芳香族氨基酸转氨酶基因arat,并对其基因序列进行生物信息学分析。方法利用PCR技术克隆得到芳香族氨基酸转氨酶基因arat的完整序列,测序后运用生物信息学软件预测arat基因对应蛋白的理化性质和结构特征。结果克隆得到了Lactobacillus plantarum LY-78的arat基因,分别命名为arat1和arat2。arat1基因全长为1 188 bp,编码395个氨基酸,蛋白相对分子质量为43 888.9,pI 5.23;arat2基因全长为1 173 bp,编码390个氨基酸,蛋白相对分子质量为43 042.6,pI 5.64;两者均为亲水、热稳定及非分泌型蛋白,具有高度保守性,均属于天冬氨酸转氨酶家族。结论通过基因克隆技术获得了2个arat基因完整序列,为今后Lactobacillus plantarum LY-78 arat基因改造及PLA合成提供了理论支持。

关键词：植物乳杆菌芳香族氨基酸转氨酶序列分析系统进化

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防止断路器合跳闸线圈烧毁的措施

冶金设备管理与维修 2017年第1期35卷 1-3页

作者：孟大庆张逊本钢职业病防治所本溪117000

分析了变电站断路器合跳闸线圈烧毁事故的原因，提出了在合闸脉冲信号发出后延时断开合跳闸回路的改进措施。

关键词：高压断路器合闸跳闸线圈烧毁

Characteristic changes in astrocyte properties during astrocyte-to-neuron conversion induced by NeuroD1/Ascl1/Dlx2

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Neural Regeneration Research 2025年第6期20卷 1801-1815页

作者： qing He Zhen Wang Yuchen Wang Mengjie Zhu Zhile Liang Kanghong zhang Yuge Xu Gong Chen GHM Institute of CNS Regeneration Jinan UniversityGuangzhouGuangdong ProvinceChina

Direct in vivo conversion of astrocytes into functional new neurons induced by neural transcription factors has been recognized as a potential new therapeutic intervention for neural injury and degenerative disorders. However, a few recent studies have claimed that neural transcription factors cannot convert astrocytes into neurons, attributing the converted neurons to pre-existing neurons mis-expressing transgenes. In this study, we overexpressed three distinct neural transcription factors––NeuroD1, Ascl1, and Dlx2––in reactive astrocytes in mouse cortices subjected to stab injury, resulting in a series of significant changes in astrocyte properties. Initially, the three neural transcription factors were exclusively expressed in the nuclei of astrocytes. Over time, however, these astrocytes gradually adopted neuronal morphology, and the neural transcription factors was gradually observed in the nuclei of neuron-like cells instead of astrocytes. Furthermore,we noted that transcription factor-infected astrocytes showed a progressive decrease in the expression of astrocytic markers AQP4(astrocyte endfeet signal), CX43(gap junction signal), and S100β. Importantly, none of these changes could be attributed to transgene leakage into preexisting neurons. Therefore, our findings suggest that neural transcription factors such as NeuroD1, Ascl1, and Dlx2 can effectively convert reactive astrocytes into neurons in the adult mammalian brain.

关键词： aquaporin-4 Ascl1 astrocyte cortex Dlx2 gap junction glia-to-neuron conversion neural regeneration NeuroD1 reprogramming

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引进CRM开创图书馆服务新局面

图书馆论坛 2003年第2期23卷 10-12页

作者：郑大庆张立厚高京广广东工业大学经济管理学院广东广州510090

作者认为随着信息技术的到来 ,图书的存在形式受到了严峻的挑战 ;读者需求的多样化 ,也使图书馆客户服务体系亟待改进。文章阐述了在实现图书馆信息化的同时 ,引入客户关系管理 (CRM )来提高图书馆的管理水平。

关键词： CRM 图书馆管理用户服务客户关系管理