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木瓜蛋白酶与石膏制动建立兔膝骨关节炎模型的比较

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广东医学 2017年第14期38卷 2114-2118页

作者：陈达彭力平廖州伟李媛胡烈奎余阗马笃军深圳市中医院骨一科广东深圳518033

目的比较木瓜蛋白酶关节腔注射与关节石膏伸直位制动建立兔膝骨关节炎模型的效果。方法将21只实验兔采用随机区组分组法分为正常组、木瓜蛋白酶组及石膏组,每组7只。木瓜蛋白酶组予6%木瓜蛋白酶生理盐水溶液于实验开始第1、4、7天行右... 详细信息

目的比较木瓜蛋白酶关节腔注射与关节石膏伸直位制动建立兔膝骨关节炎模型的效果。方法将21只实验兔采用随机区组分组法分为正常组、木瓜蛋白酶组及石膏组,每组7只。木瓜蛋白酶组予6%木瓜蛋白酶生理盐水溶液于实验开始第1、4、7天行右膝关节腔注射,注射结束4周后造模完成;石膏组予膝关节伸直位固定6周;记录实验期间动物不良情况发生率,造模完成后处死实验兔,取软骨标本进行大体观察、Pelletier评分、Mankin's评分,免疫组化测定软骨Ⅱ型胶原蛋白含量,EliSA法检测血清和关节液中肿瘤坏死因子-α(TNF-α)、软骨寡聚基质蛋白(COMP)以及基质金属蛋白酶-3(MMP-3)的含量。结果大体观察显示木瓜蛋白酶组与石膏组均出现关节肿胀、关节间隙变窄、软骨缺损、滑膜增生硬化、炎症改变、骨赘形成;Pelletier评分、Mankin's评分、Ⅱ型胶原蛋白含量、血清和关节液中TNF-α、COMP以及MMP-3的含量,木瓜蛋白酶组、石膏组与正常组比较,差异均有统计学意义(P0.05)。木瓜蛋白酶组动物不良情况发生率明显低于石膏组,差异有统计学意义(P<0.01)。结论木瓜蛋白酶关节腔注射与石膏关节伸直位制动均能成功建立膝骨关节炎模型,但木瓜蛋白酶关节腔注射法更为快捷、简便,并发情况少,可行性好。

关键词：木瓜蛋白酶石膏制动膝骨关节炎动物模型

盆底功能障碍治疗中实施补中益气汤加味的临床研究

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中西医结合心血管病电子杂志 2021年第4期9卷 136-138页

作者：文芳芳冯雪萍彭达丽江西省萍乡市湘东区妇幼保健院江西省萍乡市上栗县妇幼保健院江西省萍乡市赣西医院

目的观察盆底功能障碍治疗中实施补中益气汤加味的效果。方法选取盆底功能障碍80例患者，分为对照组与观察组，各40例，为对照组提供常规康复治疗，为观察组增加补中益气汤加味治疗。对比治疗后两组的盆底肌力恢复效果、盆腔脏器脱垂... 详细信息

目的观察盆底功能障碍治疗中实施补中益气汤加味的效果。方法选取盆底功能障碍80例患者，分为对照组与观察组，各40例，为对照组提供常规康复治疗，为观察组增加补中益气汤加味治疗。对比治疗后两组的盆底肌力恢复效果、盆腔脏器脱垂、压力性尿失禁情况及生活质量。结果与对照组相比，观察组盆底肌力受损率较低，盆底功能恢复较好，治疗3个疗程后，与对照组相比，观察组的UDL-7评分较低，对比P<0.05。结论为存在产后盆底功能障碍性疾病的患者提供补中益气汤加味治疗，可以改善个体的盆底肌力情况，减少出现盆腔脏器脱垂的问题，提高生活质量，促进恢复正常[1]，效果十分显著。

关键词：盆底功能障碍补中益气汤加味盆底肌力生活质量

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儿童血铅水平与厌食症相关性研究

青岛医药卫生 2012年第3期44卷 189-190页

作者：李晓华崔荣太彭大力刘薇北京市海淀区万寿路医院防保科北京100036 解放军总医院神经内科青岛市儿童医院检验科

目的探讨儿童厌食症与血铅水平关系。方法对2006年6月至2009年6月就诊、年龄3～12岁的112例儿童厌食症患儿按年龄段分组,采用原子吸收光谱仪测定血铅,并与同年龄段正常儿童血铅结果进行比较。结果儿童厌食症铅中毒率为47.3%,明显高于对... 详细信息

目的探讨儿童厌食症与血铅水平关系。方法对2006年6月至2009年6月就诊、年龄3～12岁的112例儿童厌食症患儿按年龄段分组,采用原子吸收光谱仪测定血铅,并与同年龄段正常儿童血铅结果进行比较。结果儿童厌食症铅中毒率为47.3%,明显高于对照组13.2%(P<0.05)。除11～年龄段外,其余年龄段儿童厌食症血铅水平明显高于对照组(P<0.05)。结论儿童厌食症与血铅水平密切相关,应该积极开展儿童铅中毒的防治工作。

关键词：儿童厌食症血铅水平研究

A NEW NUMERICAL WAVE FLUME COMBINING THE 0-1 TYPE BEM AND THE VOF METHOD

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Journal of Hydrodynamics 2012年第4期24卷 506-517页

作者： GUO li-dong SUN da-peng WU Hao State Key Laboratory of Coastal and Offshore Engineering Dalian University of TechnologyDalian 116024China

A new coupling numerical wave model, based on both the Boundary Element Method （BEM） and the Volume Of Fluid （VOF） method, is established by taking advantages of the both methods to solve the wave-structure interaction problems. In this model, the wave transformation in front of structures is calculated by the 0-1 type BEM, and the intense wave motions near the structures are calculated by the VOF method. In this paper, the characteristics of the BEM and the VOF method are discussed first, and then the coupling treatments are described in detail. In the end, the accuracy and the validity of the coupling model are examined by comparing the numerical results with experiment results and other numerical results available for the interactions between regular waves with a monolayer horizontal plate.

关键词： Boundary Element Method (BEM) Volume Of Fuid (VOF) method coupling numerical wave model horizontal plate

不同沙土配比对盆栽平邑甜茶的生长及^(15)N吸收、利用和损失的影响

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水土保持学报 2011年第4期25卷 131-134页

作者：房祥吉姜远茂彭福田魏绍冲葛顺峰张大鹏崔同丽山东农业大学园艺科学与工程学院山东农业大学作物生物学国家重点实验室山东泰安271018

以当年生盆栽平邑甜茶为试材,应用15N同位素示踪技术研究不同沙土配比(不加沙、沙/(沙+土)=20%、40%、60%、80%、纯沙)对植株的生长及15N吸收、利用和损失的影响。结果表明:不同的沙土配比处理,平邑甜茶植株具有不同的生长状况及氮素吸... 详细信息

以当年生盆栽平邑甜茶为试材,应用15N同位素示踪技术研究不同沙土配比(不加沙、沙/(沙+土)=20%、40%、60%、80%、纯沙)对植株的生长及15N吸收、利用和损失的影响。结果表明:不同的沙土配比处理,平邑甜茶植株具有不同的生长状况及氮素吸收、利用和损失。沙土配比20%处理的植株生长量(株高、茎粗和总干重)最大(37.54 cm,3.457 mm和16.20 g),60%处理的全氮和15N吸收量最大,分别为189.31,32.39 mg,20%～60%处理下的生长量与氮素吸收、利用要显著高于不加沙和高沙处理(沙土配比>60%)。各处理的Ndff值和15N分配率均为地上部>地下部,20%～80%处理的植株各部分Ndff值随沙土配比的增大而增大。土壤中15N残留量与土壤沙土配比大小呈负相关,随着沙土配比增大,氮素总损失呈现增大的趋势。平邑甜茶植株生长和养分吸收、利用与土壤质地密切相关,适宜的沙土配比有利于植株的生长和氮素吸收、利用,较高的沙土配比加剧了土壤氮素损失。

关键词：平邑甜茶沙土配比 15N 吸收利用损失

Development of a linear compressor for two-stage pulse tube cryocoolers

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2009年第11期10卷 1595-1600页

作者： peng-da YAN Wei-li GAO Guo-bang CHEN Institute of Refrigeration and Cryogenics Zhejiang University Hangzhou 310027 China

A valveless linear compressor was built up to drive a self-made two-stage pulse tube cryocooler. With a designed maximum swept volume of 60 cm3, the compressor can provide the cryocooler with a pressure volume (PV) power of 400 W. Preliminary measurements of the compressor indicated that both an efficiency of 35%～55% and a pressure ratio of 1.3～1.4 could be obtained. The two-stage pulse tube cryocooler driven by this compressor achieved the lowest temperature of 14.2 K.

关键词： linear compressor linear motor Pulse tube cryocooler

Two-phase sink vortex suction mechanism and penetration dynamic characteristics in ladle teeming process

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Journal of Iron and Steel Research International 2017年第7期24卷 669-677页

作者： da-peng Tan Ye-sha Ni li-bin Zhang Key Laboratory of E & M Ministry of Education & Zhejiang ProvinceZhejiang University of Technology

At the late stage of continuous casting（CC）ladle teeming,sink vortex can suck the liquid slag into tundish,and cause negative influences on the cleanliness of molten *** address this issue,a twophase fluid mechanical modeling method for ladle teeming was ***,a dynamic model for vortex suction process was built,and the profiles of vortex flow field were ***,based on the level set method（LSM）,a two-phase 3Dinterface coupling model for slag entrapment was ***,in combination with high-order essentially non-oscillatory（ENO）and total variation diminishing（TVD）methods,a LSM-based numerical solution method was proposed to obtain the 3Dcoupling evolution regularities in vortex suction *** results show that the vortex with higher kinetic energy can form an expanded sandglass-shape region with larger slag fraction and lower rotating velocity;there is a pressure oscillation phenomenon at the vortex penetration state,which is caused by the energy shock of two-phase vortex penetration coupling.

关键词： Ladle teeming Sink vortex Suction mechanism Two-phase coupling Level set method Pressure oscillation

Postural effect on manual laterality during grooming in northern white-cheeked gibbons(Nomascus leucogenys)

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Zoological Research 2019年第5期40卷 449-455页

作者： da-peng Zhao Bo-Song li Bao-Guo li Tianjin Key Laboratory of Animal and Plant Resistance College of Life Sciences Tianjin Normal University Tianjin 300387 China Shaanxi Key Laboratory for Animal Conservation College of Life Sciences Northwest University Xi’an Shaanxi 710069 China Center for Excellence in Animal Evolution and Genetics Chinese Academy of Sciences Kunming Yunnan 650223 China

Investigations on manual laterality in non-human primates can help clarify human evolutionary origins of hand preference and cerebral cognition. Although body posture can influence primate hand preference, investigations on how posture affects hylobatid manual laterality are still in their infancy. This study focused on how spontaneous bipedal behavioral tasks affect hand preference in Hylobatidae. Ten captive northern white-cheeked gibbons (Nomascus leucogenys) were chosen as focal subjects. Unimanual grooming during sitting posture and supported bipedal posture were applied as behavioral tasks. The gibbons displayed a modest tendency on left-hand preference during sitting posture and right-hand preference during supported bipedal posture, although no group-level hand preference was detected for either posture. From the sitting to supported bipedal posture, 70% of individuals displayed different degrees of right-side deviation trends. The strength of manual laterality in the supported bipedal posture was higher than that in the sitting posture. We found significant sex differences in manual laterality during supported bipedal posture but not during sitting posture. Thus, to a certain degree, bipedal posture in N. leucogenys facilitates stronger hand preference, elicits a rightward trend in manual laterality, and produces sex-specific hand preference.

关键词： Grooming Hand preference Hylobatidae Posture

P-wave tomography of crust and upper mantle under Southern California: Influence of topography of Moho discontinuity

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Acta Seismologica Sinica(English Edition) 2003年第6期16卷 577-587页

作者： HUANG Jin-li(黄金莉) ZHAO da-peng(赵大鹏) Center for Analysis and Prediction China Seismological Bureau Beijing 100036 China Geodynamics Research Center Ehime University Matsuyama 790 Japan

We use 146 422 P-wave arrival times from 6 347 local earthquakes recorded by the Southern California SeismicNetwork to determine a detailed three-dimensional P-wave velocity structure at 0～35 km depth. We have takeninto account the Moho depth variations, which were obtained by seismological methods. Checkerboard tests sug-gest that our inversion results are reliable. Our models provide new information on regional geological structuresof Southern California. At shallow depths P-wave velocity structure correlates with surface geological features andexpresses well variations of surface topography of the mountains and basins. The velocity structure at each layer ischaracterized by block structures bounded by large faults. Ventura Basin, Los Angeles Basin, Mojave Desert, Pen-insular Ranges, San Joaquin Valley, Sierra Nevada, and Salton Trough show respectively all-round block. SanAndreas Fault becomes an obvious boundary of the region. To its southwest, the velocity is higher, and there arestrong heterogeneity and deeper seismicity; but to its northeast, the velocity is lower and shows less variation thanto the southwest, the seismicity is shallower. To investigate the effect of the Moho geometry we conducted inver-sions for two cases: one for flat Moho geometry, another for a Moho with lateral depth variations. We found thatthe topography of the Moho greatly affects the velocity structure of the middle and lower crust. When the Mohotopography is considered, a more reasonable tomographic result can be obtained and the resulting 3-D velocitymodel fits the data better.

关键词： Southern California Moho discontinuity 3-D P-wave velocity structure block feature seismicity