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Energy loss caused by shielding effect of steel cage outside source tube

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Nuclear Science and Techniques 2007年第2期18卷 86-87页

作者： li da wang Chuanshan LUO Wenyun WEI Zhongyuan Shanghai University Shanghai 200444 China

The energy loss, produced by shielding effect of steel cage outside the source tube, is quite considerable. With PENELOPE software package, MC results have been obtained based on the simulation of different source con- formations. The result illustrates that the naked source tubes can improve the utilization ratio of the cobalt facilities. It demonstrates the applied value of the naked source tube in engineering.

关键词：辐照源管钢笼屏蔽效应能量损失 PENELOPE软件包模拟

Thermodynamics of Solvent Extraction of Rare and Scattered Metal-Indium with Diethylhexylmonothiophosphoric Acid

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Chemical Research in Chinese Universities 2006年第1期22卷 111-113页

作者： liU Xing-zhi ZANG Shu-liang FANG da-wei li Jun wang Lu-ning Institute of Chemical Science and Engineering Liaoning University Shenyang 110036 P. R. China

The thermodynamics of extracting In（ Ⅲ） with diethylhexylmonothiophosphoric acid as an extractant in a H2SO4 system is reported. The equilibrium molalities of In^3＋ ions were measured at a high acidity and ionic strengths varying from 0. 1 to 2.0 mol/kg in an aqueous phase containing Na2SO4 as the supporting electrolyte. The values of the standard extraction constant K^0 at various temperatures were obtained by the methods of extrapolation and polynomial approximation. The equation lgK^0 = - 51.95 - 5.93 × 10^3/T ＋ 6. 15 × 10^-2 T was also obtained and the thermodynamic quantities for the extraction process were calculated.

关键词： Extraction Indium Diethylhexylmonothiophosphoric acid Thermodynamics

Fresh human amniotic membrane effectively promotes the repair of injured common peroneal nerve

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Neural Regeneration Research 2019年第12期14卷 2199-2208页

作者： Zhong-Yuan Zhang Jin Yang Zhen-Hai Fan da-li wang Yu-Ying wang Tao Zhang li-Mei Yu Chang-Yin Yu Key Laboratory of Cell Engineering in Guizhou Province The Affiliated Hospital of Zunyi Medical University Zunyi Guizhou Province China Department of Thyroid and Breast Surgery Fifth People’s Hospital of Chengdu Chengdu Sichuan Province China The Team of Scientific and Technological Innovation Talents on The Basic and Clinical Research of Amniotic Membrane and Bone Marrow Stem Cells in Guizhou Province Zunyi Guizhou Province China Department of Burn and Plastic Surgery The Affiliated Hospital of Zunyi Medical University Zunyi Guizhou Province China Department of Neurology The Affiliated Hospital of Zunyi Medical University Zunyi Guizhou Province China

Suture and autologous nerve transplantation are the primary therapeutic measures for completely severed nerves. However, imbalances in the microenvironment and adhesion of surrounding tissues can affect the quality of nerve regeneration and repair. Previous studies have shown that human amniotic membrane can promote the healing of a variety of tissues. In this study, the right common peroneal nerve underwent a 5-mm transection in rats. Epineural nerve repair was performed using 10/0 non-absorbable surgical suture. The repair site was wrapped with a two-layer amniotic membrane with α-cyanoacrylate rapid medical adhesive after suture. Hindlimb motor function was assessed using footprint analysis. Conduction velocity of the common peroneal nerve was calculated by neural electrical stimulation. The retrograde axoplasmic transport of the common peroneal nerve was observed using fast blue BB salt retrograde fluorescent staining. Hematoxylin- eosin staining was used to detect the pathological changes of the common peroneal nerve sputum. The mRNA expression of axon regeneration-related neurotrophic factors and inhibitors was measured using real-time polymerase chain reaction. The results showed that the amniotic membrane significantly improved the function of the injured nerve;the toe spread function rapidly recovered, the nerve conduction velocity was restored, and the number of fast blue BB salt particles were increased in the spinal cord. The amniotic membrane also increased the recovery rate of the tibialis anterior muscle and improved the tissue structure of the muscle. Meanwhile, mRNA expression of nerve growth factor, growth associated protein-43, collapsin response mediator protein-2, and brain-derived neurotrophic factor recovered to near-normal levels, while lingo-1 mRNA expression decreased significantly in spinal cord tissues. mRNA expression of glial-derived neurotrophic factor did not change significantly. Changes in mRNA levels were more significant in amniot

关键词： nerve regeneration human amniotic membrane axonal Schwann cells α-cyanoacrylate rapid medical adhesive neural suture tibial anterior muscle neuronal growth factor common peroneal nerve injury neural regeneration

Thermal effects on structure and photoluminescence properties of diamond-like carbon films prepared by pulsed laser deposition

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Optoelectronics Letters 2006年第3期2卷 182-185页

作者： CHEN da li Qing-shan wang Jing-jing ZHENG Xue-gang College of Physics and Engineering Qufu Normal University Qufu 273165 China

Un-hydrogenated Diamond-like Carbon （DLC） films were prepared by pulsed laser deposition technique at different substrate temperature. The Raman spectra, the absorption and the photoluminescence spectra were measured. The dependence of structure and phetoluminescence properties on deposition temperature were studied in detail. The experimental results indicate that the sp^2 sites form small clus ters that consist of both olefinic chains and aromatic ring groups within the sp^3 matrix. With raising deposition temperature,the optical band gaps increase from 1.87 to 2.85 eV. The main band of photoluminescence centered at around 700nm shifts to short wavelength, and the intensity of this band increases. The photoluminescence can be attributed to carrier localization within an increasing sp^2 clusters. It was clarified that the DLC films are ordered with increasing deposition temperature.

关键词：碳薄膜光致发光金刚石脉冲激光沉积作用光谱

Loss of GSNOR1 Function Leads to Compromised Auxin Signaling and Polar Auxin Transport

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Molecular Plant 2015年第9期8卷 1350-1365页

作者： Ya-Fei Shi da-li wang Chao wang Angela Hendrickson Culler Molly A. Kreiser Jayanti Suresh Jerry D. Cohen Jianwei Pan Barbara Baker Jian-Zhong liu College of Chemistry and life Sciences Zhejiang Normal University Jinhua Zhejiang 321004 China Department of Plant and Microbial Biology University of California Berkeley Berkeley CA 94720 USA Department of Horticultural Science Microbial and Plant Genomics Institute University of Minnesota Saint Paul MN 55108 USA These authors contributed equally to this article.

Cross talk between phytohormones, nitric oxide （NO）, and auxin has been implicated in the control of plant growth and development. Two recent reports indicate that NO promoted auxin signaling but inhibited auxin transport probably through S-nitrosylation. However, genetic evidence for the effect of S-nitrosylation on auxin physiology has been lacking. In this study, we used a genetic approach to understand the broader role of S-nitrosylation in auxin physiology in Arabidopsis. We compared auxin signaling and transport in Col-0 and gsnorl-3, a loss-of-function GSNOR1 mutant defective in protein de-nitrosylation. Our results showed that auxin signaling was impaired in the gsnorl-3 mutant as revealed by significantly reduced DR5-GUS/ DR5-GFP accumulation and compromised degradation of AXR3NT-GUS, a useful reporter in interrogating auxin-mediated degradation of Aux/IAA by auxin receptors. In addition, polar auxin transport was compro- mised in gsnorl-3, which was correlated with universally reduced levels of PIN or GFP-PIN proteins in the roots of the mutant in a manner independent of transcription and 26S proteasome degradation. Our results suggest that S-nitrosylation and GSNORl-mediated de-nitrosylation contribute to auxin physiology, and impaired auxin signaling and compromised auxin transport are responsible for the auxin-related morpho- logical phenotypes displayed by the gsnorl-3 mutant.

关键词： phytohormone cross talk S-nitrosoglutathione reductase (GSNOR) S-nitrosylation auxin signaling,auxin transport Arabidopsis

Log odds of positive lymph nodes is a better prognostic factor for oesophageal signet ring cell carcinoma than N stage

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World Journal of Clinical Cases 2021年第1期9卷 24-35页

作者： Feng wang Shu-Geng Gao Qi Xue Feng-Wei Tan Yu-Shun Gao You-Sheng Mao da-li wang Jun Zhao Yin li Xiang-Yang Yu Hong Cheng Chen-Guang Zhao Ju-Wei Mu Department of Thoracic Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China

BACKGROUND Signet ring cell carcinoma is a rare type of oesophageal cancer,and we hypothesized that log odds of positive lymph nodes(LODDS)is a better prognostic factor for oesophageal signet ring cell *** To explore a novel prognostic factor for oesophageal signet ring cell carcinoma by comparing two lymph node-related prognostic factors,log odds of positive LODDS and N *** A total of 259 cases of oesophageal signet ring cell carcinoma after oesophagectomy were obtained from the Surveillance,Epidemiology,and End Results database between 2006 and *** prognostic value of LODDS and N stage for oesophageal signet ring cell carcinoma was evaluated by univariate and multivariate *** Akaike information criterion and Harrell’s C-index were used to assess the value of two prediction models based on lymph *** validation was performed to further confirm the *** The 5-year cancer-specific survival(CSS)and 5-year overall survival(OS)rates of all the cases were 41.3%and 27.0%,*** Kaplan-Meier method showed that LODDS had a higher score of log rank chi-squared(OS:46.162,CSS:41.178)than N stage(OS:36.215,CSS:31.583).Univariate analyses showed that insurance,race,T stage,M stage,TNM stage,radiation therapy,N stage,and LODDS were potential prognostic factors for OS(Plidation were consistent with those in the study *** LODDS is a superior prognostic factor to N stage for patients with oesophageal signet ring cell

关键词： Oesophageal neoplasms Signet ring cell Lymph nodes Prognosis Log odds of positive lymph nodes TNM stage

*** outcomes of 307 patients after complete thymoma resection

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Chinese Journal of Cancer 2017年第10期36卷 488-496页

作者： Zu-Yang Yuan Shu-Geng Gao Ju-Wei Mu Qi Xue You-Sheng Mao da-li wang Jun Zhao Yu-Shun Gao Jin-Feng Huang Jie He Department of Thoracic Surgery National Cancer Center/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021 P. R. China

Background: Thymoma is an uncommon tumor without a widely accepted standard care to date. We aimed to investigate the clinicopathologic variables of patients with thymoma and identify possible predictors of survival and recurrence after initial ***: We retrospectively selected 307 patients with thymoma who underwent complete resection at the Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College(Beijing, China) between January 2003 and December 2014. The associations of patients' clinical characteristics with prognosis were estimated using Cox regression and Kaplan–Meier survival ***: During follow?up(median, 86 months; range, 24–160 months), the 5? and 10?year disease?free survival(DFS) rates were 84.0% and 73.0%, respectively, and the 5? and 10?year overall survival(OS) rates were 91.0% and 74.0%, respectively. Masaoka stage(P < 0.001), World Health Organization(WHO) histological classification(P < 0.001), and postoperative radiotherapy after initial resection(P = 0.006) were associated with recurrence(52/307, 16.9%). Multivariate analysis revealed that, after initial resection, WHO histological classification and Masaoka stage were independent predictors of DFS and OS. The pleura(25/52, 48.0%) were the most common site of recurrence, and locoregional recurrence(41/52, 79.0%) was the most common recurrence pattern. The recurrence pattern was an independent predictor of post?recurrence survival. Patients with recurrent thymoma who underwent repeated resec?tion had increased post?recurrence survival rates compared with those who underwent therapies other than surgery(P = 0.017).Conclusions: Masaoka stage and WHO histological classification were independent prognostic factors of thymoma after initial complete resection. The recurrence pattern was an independent predictor of post?recurrence survival. Locoregional recurrence and repeated resection of the recurrent tumor were associated with favorable prognosis.

关键词： Thymoma Complete resection Recurrent thymoma Prognosis

Updated experiences with minimally invasive Mc Keown esophagectomy for esophageal cancer

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World Journal of Gastroenterology 2015年第45期21卷 12873-12881页

作者： Ju-wei Mu Shu-geng gao Qi Xue You-Sheng Mao da-li wang Jun Zhao Yu-Shun gao Jin-feng Huang Jie He Department of Thoracic Surgical Oncology Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical College

AIM: To update our experiences with minimally invasive Mc Keown esophagectomy for esophageal ***: we retrospectively reviewed the medical records of 445 consecutive patients who underwent minimally invasive Mc Keown esophagectomy between January 2009 and July 2015 at the Cancer Hospital of Chinese Academy of Medical Sciences and used 103 patients who underwent open Mc Keown esophagectomy in the same period as controls. Among 375 patients who underwent total minimally invasive Mc Keown esophagectomy, 180 in the early period were chosen for the study of learning curve of total minimally invasive Mc Keown esophagectomy. These 180 minimally invasive Mc Keown esophagectomies performed by five surgeons were divided into three groups according to time sequence as group 1(n = 60), group 2(n = 60) and group 3(n = 60).RESULTS: Patients who underwent total minimally invasive Mc Keown esophagectomy had significantly less intraoperative blood loss than patients who underwent hybrid minimally invasive Mc Keown esophagectomy or open Mc Keown esophagectomy(100 ml vs 300 ml vs 200 ml, P = 0.001). However, there were no significant differences in operation time, number of harvested lymph nodes, or postoperative morbidity includingincidence of pulmonary complication and anastomotic leak between total minimally invasive Mc Keown esophagectomy, hybrid minimally invasive Mc Keown esophagectomy and open Mc Keown esophagectomy groups. There were no significant differences in 5-year survival between these three groups(60.5% vs 47.9% vs 35.6%, P = 0.735). Patients in group 1 had significantly longer duration of operation than those in groups 2 and 3. There were no significant differences in intraoperative blood loss, number of harvested lymph nodes, or postoperative morbidity including incidence of pulmonary complication and anastomotic leak between groups 1, 2 and ***: Total minimally invasive Mc Keown esophagectomy was associated with reduced intraoperative blood loss a

关键词： Surgical procedures Minimally invasive Esophagecto

Application of video-assisted thoracic surgery in the standard operation for thoracic tumors

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Cancer Biology & Medicine 2013年第1期10卷 28-35页

作者： Ju-Wei Mu Gui-Yu Chen Ke-lin Sun da-Wei wang Bai-Hua Zhang Ning li Fang Lv You-Sheng Mao Qi Xue Shu-Geng Gao Jun Zhao da-li wang Zhi-Shan li Wen-Dong Lei Yu-Shun Gao liangze Zhang Jin-Feng Huang Kang Shao Kai Su Kun Yang liang Zhao Fei-Yue Feng Yong-Gang wang Jian li Jie He Department of Thoracic Surgical Oncology Cancer Institute & Hospital Chinese Academy of Medical Sciences

Objective： To evaluate the short-term outcomes of video-assisted thoracic surgery （VATS） for thoracic tumors. Methods： The data of 1,790 consecutive patients were retrospectively reviewed. These patients underwent VATS pulmonary resections, VATS esophagectomies, and VATS resections of mediastinal tumors or biopsies at the Cancer Institute ＆ Hospital, Chinese Academy of Medical Sciences between January 2009 and January 2012. Results： There were 33 patients converted to open thoracotomy （OT, 1.84%）. The overall morbidity and mortality rate was 2.79% （50/1790） and 0.28% （5/1790）, respectively. The overall hospitalization and chest tube duration were shorter in the VATS lobectomy group （n=949） than in the open thoracotomy （OT） lobectomy group （n=753）. There were no significant differences in morbidity rate, mortality rate and operation time between the two groups. In the esophageal cancer patients, no significant difference was found in the number of nodal dissection, chest tube duration, morbidity rate, mortality rate, and hospital length of stay between the VATS esophagectomy group （n=8 1） and open esophagectomy group （n=81）. However, the operation time was longer in the VATS esophagectomy group. In the thymoma patients, there was no significant difference in the chest tube duration, morbidity rate, mortality rate, and hospital length of stay between the VATS thymectomy group （n=41） and open thymectomy group （n=41）. However, the operation time was longer in the VATS group. The median tumor size in the VATS thymectomy group was comparable with that in the OT group. Conclusions： In early-stage （Ⅰ/Ⅱ） non-small cell lung cancer patients who underwent lobectomies, VATS is comparable with the OT approach with similar short-term outcomes. In patients with resectable esophageal cancer, VATS esophagectomy is comparable with OT esophagectomy with similar morbidity and mortality. VATS thymectomy for Masaoka stage I and II thymoma is feasible and safe, and tumor size is not contr

关键词： Video-assisted thoracic surgery (VATS) non-small cell lung cancer (NSCLC) esophageal cancer thymoma