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Food Science and Human Wellness 2024年第2期13卷 659-667页

作者： Lanlan Gui Shaokang Wang Jing Wang Wang Liao Zitong Chen da pan Hui Xia Guiju Sun Su Tian Department of Nutrition and Food Hygiene School of Public HealthSoutheast UniversityNanjing 210009China Nanjing Municipal Center for Disease Control and Prevention Nanjing 210003China Department of Nutrition and Food Hygiene School of Public HealthHebei Medical UniversityShijiazhuang 050017China

Forsythia suspensa,belonging to the deciduous shrubs of the Luteaceae family,a traditional Chinese medicine,has effects of alleviating swelling,clearing heat,detoxification and promoting blood *** leaves of *** contain multiple chemical components and have a long history of use in folk medicines and health *** purpose of this study was to explore the effects of forsythin extract from *** leaves on intestinal microbiota and short-chain fatty acid(SCFA)content in rats with obesity induced by a high-fat *** extract in *** leaves increased the abundance of the intestinal microbiota,ameliorated intestinal microbiota disorders and inhibited the increase in total SCFA content in the intestinal tract in rats with obesity induced by a high-fat *** results suggested that forsythin extract in *** leaves may slow the development of obesity induced by a high-fat diet;thus,its active components and efficacy are worthy of further study.

关键词： Forsythin High-fat diet Intestinal microbiota Short-chain fatty acid(SCFA)

Causal relationship between circulating vitamin C and 25-hydroxyvitamin D concentrations and common mental disorders-a Mendelian randomization study

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Food Science and Human Wellness 2024年第4期13卷 1877-1885页

作者： Yuanyuan Wang Lirong Dong Meng Zhao Shiyu Yin pan da Dengfeng Xu Yifei Lu Jiayue Xia Niannian Wang Shaokang Wang Guiju Sun Key Laboratory of Environmental Medicine and Engineering of Ministry of Education and Department of Nutrition and Food HygieneSchool of Public HealthSoutheast UniversityNanjing 210009China Department of Integrated Service and Management Jiangsu Provincial Center for Disease Control and PreventionNanjing 210009China

Mental disorders seriously affect people’s health and social *** Mendelian randomization(MR)study was designed to investigate the causal relationship between circulating vitamin C(VC)or 25-hydroxyvitamin D(25(OH)D)levels and mental *** data used for the MR analysis were derived from the summary genome-wide association studies(GWAS)database for VC and 25(OH)D and from the Finn Gen consortium for fourteen mental *** on the inverse variance weighted(IVW)method,we found a potential causal association between circulating VC and anxiety disorders(IVW:OR=1.139,95%CI:1.023-1.269,P=0.018).However,no causal association was found between VC or 25(OH)D and other mental disorders(P>0.05).In the reverse MR analysis,individuals with Alzheimer’s disease was causally associated with higher concentrations of circulating VC(P=0.012),while individuals with anxiety disorders had a negative association between the concentrations of 25(OH)D(P=0.012).However,the current evidence does not support a causal relationship between VC or 25(OH)D and other mental *** addition,there was no causal association between circulating VC and 25(OH)D(P>0.05).Future studies are needed to confirm these findings and to elucidate the mechanisms of potential causality.

关键词： Circulating vitamin C 25-Hydroxyvitamin D Mental disorder Mendelian randomization

从缔造新中国到建设新中国——中国共产党对政治话语“小米加步枪”的构建与运用

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湖北大学学报（哲学社会科学版） 2024年第4期51卷 1-9,I0002页

作者：潘大礼三峡大学马克思主义学院湖北宜昌443002

解放战争时期,“小米加步枪”经由毛泽东公开表述后,成为中国共产党的经典政治话语,它最初代表着党艰苦奋斗的政治本色和密切联系群众的优良作风,是党取得革命战争胜利的重要因素。以毛泽东为代表的中国共产党人借用日常事物形象地表达... 详细信息

解放战争时期,“小米加步枪”经由毛泽东公开表述后,成为中国共产党的经典政治话语,它最初代表着党艰苦奋斗的政治本色和密切联系群众的优良作风,是党取得革命战争胜利的重要因素。以毛泽东为代表的中国共产党人借用日常事物形象地表达抽象的政治话语,宣传党的政治主张和价值观念,实现党的意识形态在社会层面的传递和濡化。新中国成立后,“小米加步枪”形塑内政外交,成为党阐释治国理政方式的话语工具,其革命属性逐步转向建设属性。改革开放以来,“小米加步枪”不仅作为党深化军事现代化建设的话语标尺,也延伸到社会主义市场经济领域,从政治话语逐步向社会话语转变。“小米加步枪”在革命、建设、改革各时期都产生了重要影响,是党领导人民群众从缔造新中国到建设新中国历程中锻造出的政治符号,是百年来党带领中华民族从弱小不断走向强大的缩影,也是我们坚定历史自信增强历史主动的精神动力和信心源头。

关键词：中国共产党小米加步枪政治话语新中国

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基于双重乳液对称分裂的微囊高通量可控构建

现代化工 2024年第S02期44卷 130-133,139页

作者：范林玲潘大伟汪伟褚良银四川大学化学工程学院四川成都610065 四川大学高分子材料工程国家重点实验室四川成都610065

设计构建了一种用于双重乳液高通量可控构建的三级分裂微流控装置,并深入分析了多级分裂后最终双重乳液的尺寸与单分散性。此外,以油-油-水(O/O/W)双重乳液为模板合成了尺寸均一的核壳型三羟甲基丙烷乙氧基三丙烯酸酯(ETPTA)微囊。相关... 详细信息

设计构建了一种用于双重乳液高通量可控构建的三级分裂微流控装置,并深入分析了多级分裂后最终双重乳液的尺寸与单分散性。此外,以油-油-水(O/O/W)双重乳液为模板合成了尺寸均一的核壳型三羟甲基丙烷乙氧基三丙烯酸酯(ETPTA)微囊。相关研究结果可为高度单分散双重乳液及微囊的高通量可控构建提供理论指导。

关键词：微流控 Y型通道对称分裂双重乳液微囊

Performance Validation and Analysis for Multi-Method Fusion Based Image Quality Metrics in A New Image database

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China Communications 2019年第8期16卷 147-161页

作者： Xiaoyu Ma Xiuhua Jiang da pan Communication and Information Technology School Communication University of China

Considering that there is no single full reference image quality assessment method that could give the best performance in all situations, some multi-method fusion metrics were proposed. Machine learning techniques are often involved in such multi-method fusion metrics so that its output would be more consistent with human visual perceptions. On the other hand, the robustness and generalization ability of these multi-method fusion metrics are questioned because of the scarce of images with mean opinion scores. In order to comprehensively validate whether or not the generalization ability of such multi-method fusion IQA metrics are satisfying, we construct a new image database which contains up to 60 reference images. The newly built image database is then used to test the generalization ability of different multi-method fusion IQA metrics. Cross database validation experiment indicates that in our new image database, the performances of all the multi-method fusion IQA metrics have no statistical significant different with some single-method IQA metrics such as FSIM and MAD. In the end, a thorough analysis is given to explain why the performance of multi-method fusion IQA framework drop significantly in cross database validation.

关键词： full reference image quality assessment image database multi-method fusion

新型咪唑类热潜伏型固化促进剂的合成及性能研究

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热固性树脂 2024年第2期39卷 7-14页

作者：刘华潘大伟刘坐镇华东理工大学华昌聚合物有限公司上海防腐蚀新材料工程技术研究中心上海200237 华东理工大学材料科学与工程学院上海200237

由六氯环三磷腈(HCCP)与5,6二甲基苯并咪唑(DBM)反应合成了具有星型结构的咪唑衍生物DBCP。采用傅里叶变换红外光谱(FT-IR)、核磁共振氢谱(1H-NMR)和磷谱(31P-NMR)及飞行时间质谱(TOF-MS)对DBCP的化学结构进行了表征。以DBCP为促进剂加... 详细信息

由六氯环三磷腈(HCCP)与5,6二甲基苯并咪唑(DBM)反应合成了具有星型结构的咪唑衍生物DBCP。采用傅里叶变换红外光谱(FT-IR)、核磁共振氢谱(1H-NMR)和磷谱(31P-NMR)及飞行时间质谱(TOF-MS)对DBCP的化学结构进行了表征。以DBCP为促进剂加入到甲基六氢邻苯二甲酸酐(MeHHPA)固化的双酚A型环氧树脂(DGEBA)体系中,用示差扫描量热法(DSC)和旋转流变仪分别研究DBCP促进体系的固化行为与室温储存稳定性。结果显示,DBCP促进体系的表观活化能较低(68.82 kJ/mol),200℃下具有明显的固化放热峰,160℃下2 min36 s能够快速完成固化,且具有大于30 d的室温储存稳定性,表明DBCP具有加快固化反应速率,降低固化温度的效果,是一种能够长期潜伏,快速固化的环氧热潜伏性固化促进剂。动态热机械分析(DMA)、热重分析(TG)和冲击试验结果表明,DBCP促进体系具有良好的热性能和力学性能。

关键词：环氧树脂固化促进剂热潜伏咪唑合成

The Different variable structure control strategy applied in power system load frequency control 25th

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The Different variable structure control strategy applied in...

Trend and Interannual Variability of Chinese Air Pollution since 2000 in Association with Socioeconomic Development: A Brief Overview

第25届中国控制与决策会议

作者： Mi yang pan da Wu xiao The School of Electric Power Engineering Shanghai University of Electric Power

ISBN: (纸本)9781467355339

For single area power system, a variable structure load frequency controller based on constant reaching law is proposed. Firstly, the original system is converted into standard type through the elementary transformation matrix, and the switching surface is designed based on the standard type, at the same time, the switching function is selected properly by using the pole assignment method which assure the sliding mode is stable. Secondly, the sliding mode controller is designed by using the constant reaching law, which can assure the hitting condition is satisfied. Finally, the power system model is used by simulation considering the ideal working condition and with generation rate constraint. The simulation results illustrate the effectiveness and robust of the designed controller.

关键词： frequency control constant reaching law variable structure control generation rate constraint (GRC)

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Atmospheric and Oceanic Science Letters 2013年第2期6卷 84-89页

作者： LIN Jin-Tai pan da ZHANG Rui-Xiong Department of Atmospheric and Oceanic Sciences & Laboratory for Climate and Ocean-Atmosphere Studies School of Physics Peking University

Abstract Chinese air pollution has increased in this century along with the rapid socioeconomic development and resulting anthropogenic emissions. While recent emission control measures have shown encouraging re sults and have reduced the levels of sulfur dioxide and primary aerosols, the concentrations of other air pollutants continue to grow, particularly secondary pollutants in cluding ozone and secondary aerosols. Meanwhile, a va riety of intentional and unintentional socioeconomic events have temporarily changed the pace, and even the signs, of growth of air pollution. These events include the short-term emission restrictions imposed during the Sino-African Summit, the Beijing Olympics and Para lympics, the Shanghai World Exposition （Shanghai Expo）, the Guangzhou Asian Olympics, and the Shenzhen Uni versiade, as well as the unintentional emission reductions associated with the recent economic recession and the annual Chinese New Year. This paper presents a brief overview of trends and temporary perturbations of Chi nese air pollution since 2000, summarizing studies on anthropogenic emission inventories, atmospheric meas urements, and inverse modeling. It concludes with rec ommendations for future research.

关键词： air pollution trend and variability socioeconomic development satellite measurements bottom-upemission inventories top-down constraints

Identification and Quantitative Analysis of Significantly Accumulated Proteins During the Arabidopsis Seedling De-etiolation Process

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Journal of Integrative Plant Biology 2006年第1期48卷 104-113页

作者： Bai-Chen Wang Ying-Hong pan da-Zhe Meng Yu-Xian Zhu The National Laboratory of Protein Engineering and Plant Genetic Engineering College of Life Sciences Peking University Beijing 100871 China

Proteomic analysis was performed on seedlings after different light treatments. A total of （1 350±31） protein spots was separated and visualized on each silver nitrate-stained two-dimensional gel using protein samples prepared from light-grown or etiolated seedlings with or without 6-9 h light treatment. Twenty-five protein spots （encoded by 19 genes） that were significantly accumulated upon light treatment were identified using the matrix-assisted laser desorption ionization time-of-flight mass spectrometry method. Functional proteomics indicated that these proteins involved mainly in chloroplast development, energy metabolism, cell cycle progression and membrane electron transport. For 18 of the protein-coding genes we identified through an internet search, the transcript levels of 17 genes matched roughly with their protein content in etiolated and green seedlings, suggesting that these genes were regulated by light mainly at the transcriptional level. Despite a very significant increase in the amount of proteins upon light treatment, similar RNA levels were found in dark-grown or green seedlings for the carbonic anhydrase gene At3g05100, indicating a possible post-transcriptional regulatory mechanism. Elucidation of light-induced protein accumulation will undoubtedly enhance our understanding of plant photomorphogenesis.

关键词： Arabidopsis de-etiolation light two-dimensional electrophoresis.

High levels of serum platelet-derived growth factor-AA and human epidermal growth factor receptor-2 are predictors of colorectal cancer liver metastasis

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World Journal of Gastroenterology 2017年第7期23卷 1233-1240页

作者： Hong-da pan Yi-Fan Peng Gang Xiao Jin Gu Department of Gastrointestinal Surgery Beijing Hospital National Center of Gerontology Department of Colorectal Surgery Peking University Cancer Hospital and Institute Beijing Cancer Hospital

AIM To develop predictive markers in blood for colorectal cancer liver *** Twenty colorectal cancer patients were selected and divided into two groups. Group A consisted of 10 patients whose pathological TNM stage was ⅢC(T3-4N2M0), while another 10 patients with synchronous liver metastasis(TNM stage Ⅳ) were recruited for group B. During the surgical procedure, a 10-ml drainage vein(DV) blood sample was obtained from the DV of the tumor-bearing segment prior to the ligation of the DV. At the same time, a 10-ml peripheral vein(PV) blood sample was collected via peripheral venipuncture. The serum levels of 24 molecules that are potentially involved in the mechanism of liver metastasis in both DV blood and PV blood were analyzed by using high-throughput enzyme-linked immunosorbent assay *** Univariate analysis revealed that platelet-derivedgrowth factor AA(PDGFAA) in DV blood(d PDGFAA)(P = 0.001), PDGFAA in PV blood(p PDGFAA)(P = 0.007), and human epidermal growth factor receptor-2 in PV blood(p HER2)(P = 0.001), p MMP7(P = 0.028), pR ANTES(P = 0.013), and pE GF(P = 0.007) were significantly correlated with synchronous liver metastasis. Multivariate analysis identified d PDGFAA(HR = 1.001, P = 0.033) and p HER2(HR = 1.003, P = 0.019) as independent predictive factors for synchronous liver metastasis. Besides, high peripheral HER2 level may also be a risk factor for metachronous liver metastasis, although the difference did not reach statistical significance(P = 0.06). Significant correlations were found between paired DV and PV blood levels for PDGFAA(r = 0.794, P < 0.001), but not for HER2(r = 0.189, P = 0.424).CONCLUSION PDGFAA in tumor drainage and HER2 in PV blood may be useful predictive factors for synchronous liver metastasis of colorectal cancer.

关键词： Platelet-derived growth factor AA Human epidermal growth factor receptor-2 Colorectal cancer Liver metastasis