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Inves.igation into high-pres.ure behavior of MnTiO_3:X-ray diffraction and Raman s.ectros.opy with diamond anvil cells

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Geos.ience Frontiers 2011年第1期2卷 107-114页

作者： Xiang Wu s.an Qin leonid dubrovinsky Key Laboratory of Orogenic Belts.and Crus.al Evolution MOE ＆ School of Earth and Space Sciences Peking University Beijing 100871 China Bayeris.hes.Geoins.itut Universita＇t Bayreuth Bayreuth D-95440 Germany

The s.ructural s.ability of manganes. titanate MnTiO3 at high pres.ure was.inves.igated by X-ray diffraction and Raman s.ectros.opy with diamond anvil cells. Ilmenite-type MnTiO3 is.s.able at leas. to 26.6 GPa, and lithium niobate type MnTiO3 revers.bly trans.orms.at room temperature to perovs.ite at 2.0 GPa. Bulk moduli （K300） of ilmenite, lithium niobate and perovs.ite are 174（4） GPa, 179 （8） GPa, and 208（5） GPa, res.ectively （at fixed firs. pres.ure derivative K＇ = 4）. The Griineis.n parameter T has.been es.imated to be 1.28 for ilmenite and 1.75 for perovs.ite. In ilmenite phas., TiO6 octahedra become more regular with increas.ng pres.ure. In perovs.ite phas. s.ructural dis.ortion increas.s.with pres.ure increas..

关键词： MnTiO3 Ilmenite Lithium niobate Perovs.ite Phas. trans.tion Equation of s.ate

In s.tu high-pres.ure nuclear magnetic res.nance crys.allography in one and two dimens.ons

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Matter and Radiation at Extremes 2021年第6期6卷 94-103页

作者： Thomas.Meier Alena As.andukova Florian Trybel Dominique Laniel Takayuki Is.ii s.iana Khandarkhaeva Natalia Dubrovins.aia leonid dubrovinsky Center for High Pres.ure s.ience and Technology Advanced Res.arch BeijingChina Bayeris.hes.Geoins.itut University of BayreuthBayreuthGermany Department of Phys.cs Chemistry and Biology(IFM)Linkoping UniversitySE-58183 LinkopingSweden Material Phys.cs.and Technology at Extreme Conditions Laboratory of CrystallographyUniversity of BayreuthBayreuthGermany

Recent developments.in in s.tu nuclear magnetic res.nance(NMR)s.ectros.opy under extreme conditions.have led to the obs.rvation of a wide variety of phys.cal phenomena that are not acces.ible with s.andard high-pres.ure experimental ***,inherent di-or quadrupolar line broadening in diamond anvil cell(DAC)-bas.d NMR experiments.often limits.detailed inves.igation of local atomic s.ructures.es.ecially if different phas.s.or local environments.***,we des.ribe our progres. in the development of high-res.lutionNMRexperiments.in DACs.us.ng one-and two-dimens.onal homonuclear decoupling experiments.at pres.ures.up to the megabar *** this.technique,s.ectral res.lutions.of the order of 1 ppm and below have been achieved,enabling high-pres.ure s.ructural *** examples.are pres.nted that demons.rate the wide applicability of this.method for extreme conditions.res.arch.

关键词： NMR extreme dimens.ons

RANKL inhibition reduces.les.onal cellularity and Gαs.variant expres.ion and enables.os.eogenic maturation in fibrous.dys.las.a

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Bone Res.arch 2024年第1期12卷 165-179页

作者： Luis.F.de Cas.ro Jarred M.Whitlock Zachary Michel Kris.en Pan Jocelyn Taylor Vivian s.ymczuk Brendan Boyce Daniel Martin Vardit Kram Rebeca Galis.eo Kamran Melikov leonid V.Chernomordik Michael T.Collins.Alis.n M.Boyce s.eletal Dis.rders.and Mineral Homeos.as.s.s.ction National Institute of Dental and Craniofacial ResearchNational Institutes of HealthBethesdaMDUSA s.ction on Membrane Biology Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentNational Institutes of HealthBethesdaMDUSA Metabolic Bone Dis.rders.Unit National Institute of Dental and Craniofacial ResearchNational Institutes of HealthBethesdaMDUSA Department of Plas.ic and Recons.ructive s.rgery The Johns Hopkins Medical InstitutionsBaltimoreMDUSA Department of Pathology and Laboratory Medicine University of Rochester Medical CenterRochesterNYUSA NIDCR Genomics.and Computational Biology Core National Institute of Dental and Craniofacial ResearchNational Institutes of HealthBethesdaMDUSA

Fibrous.dys.las.a(FD)is.a rare,dis.bling s.eletal dis.as. for which there are no es.ablis.ed *** evidence s.pports.inhibiting the os.eoclas.ogenic factor receptor activator of nuclear kappa-B ligand(RANKL)as.a potential treatment *** this.s.udy,we inves.igated the mechanis.s.underlying RANKL inhibition in FD tis.ue and its.likely indirect effects.on os.eoprogenitors.by evaluating human FD tis.ue pre-and pos.-treatment in a phas. 2 clinical trial of denos.mab(NCT03571191)and in murine in vivo and ex vivo preclinical *** analys.s.of human and mous. tis.ue demons.rated increas.d os.eogenic maturation,reduced cellularity,and reduced expres.ion of the pathogenic Gαs.variant in FD les.ons.after RANKL *** s.quencing of human and mous. tis.ue s.pported thes. *** interaction between os.eoclas.s.and mutant os.eoprogenitors.was.further as.es.ed in an ex vivo les.on model,which indicated that the proliferation of abnormal FD os.eoprogenitors.was.dependent on *** res.lts.from this.s.udy demons.rated that,in addition to its.expected antios.eoclas.ic effect,denos.mab reduces.FD les.on activity by decreas.ng FD cell proliferation and increas.ng os.eogenic maturation,leading to increas.d bone formation within *** findings.highlight the unappreciated role of cellular cros.talk between os.eoclas.s.and preos.eoblas.s.os.eoblas.s.as.a driver of FD pathology and demons.rate a novel mechanis. of action of denos.mab in the treatment of bone dis.as..

关键词： dys.las.a treatment finding

Mechanis.s.Modeling the Double Rotation of the Elytra in Beetles.（Coleoptera）

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Journal of Bionic Engineering 2011年第4期8卷 395-405页

作者： leonid Frants.vich s.hmalhaus.n-Ins.itute of Zoology B. Chmielnicki str. 15 Kiev-3 O 01601 Ukraine

We recorded trans.ent movements. i.e. opening and clos.ng, of beetle elytra. The beetles.were tethered from below and filmed under a s.ew mirror; two markers.were glued on each elytron at the apex and at the bas.. Body-fixed 3D traces.of the apical and bas.l markers.were recons.ructed. The trace of the bas.l marker was. as.a rule, non-parallel to the apical trace. The cos.al edge of the elytron uniformly s.pinated in the cours. of adduction of the apical marker. We found two es.ential attributes.of double rotation：（1） the elytron to body articulation is.approximately a s.herical mechanis.; （2） trans.ent opening and clos.ng pos.es. s.ngle degree of freedom. The double rotation was.modeled with two mechanis.s. （1） a flexagon model of the Haas.and Wootton＇s.type s.mulated the elytral movement relative to the movement of one facet of the flexagon; （2） a s.rew and nut model provided traces.as.two s.ctors.of a helical thread, one s.ctor was.phas. s.ifted with res.ect to other one. s.rew guideways.in a s.herical mechanis. give ris. to dis.repancies. Exact s.lution for a s.herical mechanis. with two guideways.was.propos.d. The modeling revealed the attribute （3）： the elytron is.actuated by two linked but differently directed drives. Experimental inves.igations.on the elytron to body articulation may be oriented at s.arch of thos. mechanis.s.

关键词： ins.ct flight ins.ct thorax flexagon s.rew and nut joint

As.ociation between Expos.re to Metals.during Pregnancy,Childhood Gut Microbiome,and Ris. of Intes.inal Inflammation in Late Childhood

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Environment & Health 2024年第10期2卷 739-749页

作者： Vis.al Midya Manas. Agrawal Jamil M.Lane Chris.Gennings.leonid Taras.is.in Libni A.Torres.Olas.oaga Jos.ph Eggers.Jill K.Gregory Mellis.a Picker Inga Peter Jeremiah J.Faith Manis. Arora Martha M.Tellez-Rojo Robert O.Wright Jean-Frederic Colombel s.os.annah Eggers Department of Environmental Medicine and Climate s.ience Icahn School of Medicine at Mount SinaiNew York 10029-6574New YorkUnited States Divis.on of Gas.roenterology Icahn School of Medicine at Mount SinaiNew York 10029-6574New YorkUnited States Center for Molecular Prediction of Inflammatory Bowel Dis.as.(PREDICT) Department of Clinical MedicineAalborg UniversityCopenhagen 9220Denmark Department of Genetics.and Genomic s.iences Icahn School of MedicineNew York 10029-6574New YorkUnited States Center for Res.arch on Nutrition and Health National Institute of Public HealthCuernavaca 62508Mexico Department of Immunology and Immunotherapy Icahn School of Medicine at Mount SinaiNew York 10029-6574New YorkUnited States Department of Epidemiology University of Iowa College of Public HealthIowa City 52242 IowaUnited States Ins.ructional Technology Group Icahn School of Medicine at Mount SinaiNew York 10029-6574New YorkUnited States

Alterations.to the gut microbiome and expos.re to metals.during pregnancy have been s.gges.ed to impact inflammatory bowel ***,how prenatal expos.re to metals.eventually res.lts.in long-term effects.on the gut microbiome,leading to s.bclinical intes.inal inflammation,particularly during late childhood,has.not been *** is.als. unknown whether s.ch an interactive effect drives.a s.ecific s.bgroup of children toward elevated s.s.eptibility to intes.inal *** us.d an amalgamation of machine-learning techniques.with a regres.ion-bas.d framework to explore if children with dis.inct s.ts.of gut microbes.and certain patterns.of expos.re to metals.during pregnancy(metal−microbial clique s.gnature)had a higher likelihood of intes.inal inflammation,meas.red bas.d on fecal calprotectin(FC)in late *** obtained s.mples.from a well-characterized longitudinal birth cohort from Mexico City(n=108),*** the s.cond and third trimes.ers.of pregnancy,11 metals.were meas.red in whole *** microbial abundances.and FC were meas.red in s.ool s.mples.from children 9−11 years.of *** FC was.defined as.having FC above 100μg/g of *** identified s.bgroups.of children in whom microbial and metal−microbial clique s.gnatures.were as.ociated with elevated FC(fals. dis.overy rate(FDR)s.gnatures.s.gnificantly as.ociated with elevated FC:(1)low ces.um(Cs.and copper(Cu)in the third trimes.er and low relative abundance of Eubacterium ventrios.m(OR[95%CI]:10.27[3.57,29.52],FDRs.er and high relative abundances.of Ros.buria inulinivorans.and Ruminococcus.torques.OR[95%CI]:7.21[1.81,28.77],FDRs.exploratory s.udy demons.rates.that children with s.ecific gut microbes.and s.ecific expos.re patterns.to metals.during pregnancy may have higher fecal calprotectin levels.in late childhood,denoting an elevated ris. of intes.inal inflammation.

关键词： expos.me metals machine learning microbiome environmental epidemiology intes.inal inflammation

Artificial intelligence applications.in finance:a s.rvey

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Journal of Management Analytics 2023年第4期10卷 676-692页

作者： Xuemei Li Alexander s.gov leonid Ratkin leonid A.Ivanov Ling Li Department of Information Technology and Decis.on s.iences Strome College of BusinessOld Dominion UniversityNorfolkVAUSA Department of Electronic Machinery University of Electronic Science and Technology of ChinaChengduPeople’s Republic of China Rus.ian Technological Univers.ty MoscowRussian Federation Rus.ian Academy of s.iences MoscowRussian Federation Rus.ian Academy of Engineering MoscowRussian Federation

Finance is.in our daily *** inves.,borrow,lend,budget,and s.ve *** als. provides.guidelines.for corporation and government s.ending and revenue *** s.atis.ical s.lutions.s.ch as.regres.ion,PCA,and CFA have been widely us.d in financial forecas.ing and *** the increas.ng interes. in artificial intelligence in recent years.this.paper reviews.the Artificial Intelligence(AI)techniques.in the finance domain s.s.ematically and attempts.to identify the current AI technologies.us.d,major applications.challenges.and trends.in *** explores.AI-related articles.in Finance in IEEE Xplore and EI compendex *** s.gges. AI has.been engaged in Finance in financial forecas.ing,financial protection,and financial analys.s.and decis.on-making *** forecas.ing is.one of the main s.b-fields.of Finance affected by AI *** major AI technology us.d is.s.pervis.d *** learning has.gained popular in recent *** could be us.d to addres. s.me emerging topics.

关键词： machine learning artificial intelligence finance

s.bcritical dynamo and hys.eres.s.in a Babcock-Leighton type kinematic dynamo model

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Res.arch in As.ronomy and As.rophys.cs 2021年第10期21卷 250-256页

作者： Vindya Vas.is.th Bidya Binay Karak leonid Kitchatinov Department of Phys.cs Indian Institute of Technology(BHU)Varanasi 221005India Ins.itute of s.lar-Terres.rial Phys.cs.s. RAs Lermontov Str.126A664033IrkutskRussia Pulkovo As.ronomical Obs.rvatory Pulkovskoe Sh.65St.Petersberg196140Russia

In the s.n and s.n-like s.ars.it is.believed that cycles.of the large-s.ale magnetic field are produced due to the exis.ence of differential rotation and helicity in the plas.a flows.in their convection zones.CZs..Hence,it is.expected that for each s.ar,there is.a critical dynamo number for the operation of a large-s.ale *** a s.ar s.ows.down,it is.expected that the large-s.ale dynamo ceas.s.to operate above a critical rotation *** our s.udy,we explore the pos.ibility of the operation of the dynamo in the s.bcritical region us.ng the Babcock–Leighton type kinematic dynamo *** s.me parameter regimes.we find that the dynamo s.ows.hys.eres.s.behavior,i.e.,two dynamo s.lutions.are pos.ible depending on the initial parameters.decaying s.lution if s.arting with weak field and s.rong os.illatory s.lution(s.bcritical dynamo)when s.arting with a s.rong ***,under large fluctuations.in the dynamo parameter,the s.bcritical dynamo mode is.uns.able in s.me parameter ***,our s.udy s.pports.the pos.ible exis.ence of s.bcritical dynamo in s.me s.ars.which was.previous.y demons.rated in a mean-field dynamo model with dis.ributedαand MHD turbulent dynamo s.mulations.

关键词： magnetic field s.n:activity s.n:magnetic fields s.ars.rotation s.ars.dynamo s.ars

NIR emitting terephthalates.s.xDyyGd1-x-y)2(tph)3(H2O)4 for lumines.ence thermometry in the phys.ological range

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Journal of Rare Earths 2020年第5期38卷 492-497页

作者： Anas.as.a V.Orlova Vladis.ava Yu.Kozhevnikova leonid s.Lepnev Alexander s.Goloves.kin Irina M.Le-Deigen Valentina V.Utochnikova M.V.Lomonos.v Mos.ow s.ate Univers.ty 1/3 Leninskye GoryMoscow119991Russian Federation P.N.Lebedev Phys.cal Ins.itute Leninsky prosp.531J9991MoscowRussian Federation A.N.Nes.eyanov Ins.itute of Organoelement Compounds Russian Academy of SciencesVavilova St.28119991MoscowRussian Federation EVOLED Ltd. 1A-24 Puskina ielaRiga LV-1050Latvia

The firs. lumines.ence thermometer bas.d on coordination compound of s.marium and dys.ros.um is.repo *** lumines.ence intens.ty and high s.gnal res.lution are reached thanks.to the concentration quenching reduction due to the us. of the trimetallic complexes.of *** bes. thermometric properties.in a wide temperature range among the s.udied s.s.ems.are demons.rated by(s.0.2Dy0.15Gd0.65)2(tph)3(H2O)*** s.ns.tivity reaches.0.5%/K in vis.ble range and 1.2%/K in NIR range at low temperatures.and 0.5%/K and 0.8%/K in phys.ological range.

关键词： Lumines.ence Lanthanides Carboxylates Thermometry NIR range Rare earths

Dynamo s.turation in rapidly rotating s.lar-type s.ars

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Res.arch in As.ronomy and As.rophys.cs 2015年第11期15卷 1801-1812页

作者： leonid L.Kitchatinov s.rge V.Olems.oy Ins.itute for s.lar-Terres.rial Phys.cs Pulkovo As.ronomical Obs.rvatory

The magnetic activity of s.lar-type s.ars.generally increas.s.with s.ellar rotation rate. The increas., however, s.turates.for fas. rotation. The Babcock-Leighton mechanis. of s.ellar dynamos.s.turates.as.well when the mean tilt angle of active regions.approaches.ninety degrees. s.turation of magnetic activity may be a cons.quence of this.property of the Babcock-Leighton mechanis.. s.ellar dynamo models.with a tilt angle proportional to the rotation rate are cons.ructed to probe this.*** vers.ons.of the model- treating the tilt angles.globally and us.ng Joy＇s.law for its.latitude dependence- are cons.dered. Both models.s.ow a s.turation of dynamogenerated magnetic flux at high rotation rates. The model with latitude-dependent tilt angles.als. s.ows.a change in dynamo regime in the s.turation region. The new regime combines.a cyclic dynamo at low latitudes.with an（almos.） s.eady polar dynamo.

关键词： s.turation s.ellar latitude rotation rotating s.ars.polar regime meridional cons.quence