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Fixed-Time Cluster Consensus for Multi-Agent Systems with Objective Optimization on Directed Networks

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Journal of Systems Science & Complexity 2023年第6期36卷 2325-2343页

作者： duan suna YU Zhiyong JIANG Haijun OUYANG Deqiang College of Mathematics and System Sciences Xinjiang UniversityUrumqi830017China Department of Mathematics The University of Hong KongHong Kong999077China

This paper studies the cluster consensus of multi-agent systems(MASs)with objective optimization on directed and detail balanced networks,in which the global optimization objective function is a linear combination of local objective functions of all ***,a directed and detail balanced network is constructed that depends on the weights of the global objective function,and two kinds of novel continuous-time optimization algorithms are proposed based on time-invariant and timevarying objective ***,by using fixed-time stability theory and convex optimization theory,some sufficient conditions are obtained to ensure that all agents'states reach cluster consensus within a fixed-time,and asymptotically converge to the optimal solution of the global objective ***,two examples are presented to show the efficacy of the theoretical results.

关键词： Cluster consensus directed and detail balanced network multi-agent systems(MASs) objective optimization

Secure Containment Control for Multi-Agent Systems Under Distributed Denial of Service Attacks

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Secure Containment Control for Multi-Agent Systems Under Dis...

利培酮纳米混悬原位凝胶的制备与释药特性研究

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作者： Zhongbao Wang Xin-chun Jia suna duan Wenbiao Zhai Hongpeng Li School of Automation and Software Engineering Shanxi University School of Mathematical Sciences Shanxi University

This paper investigates the secure containment control problem of general linear multi-agent systems(MASs) under the distributed denial of service(DoS) attacks. Firstly, in order to save communication resources, an distributed event-triggered mechanism is proposed. Based on the proposed distributed event-triggered mechanisms and the distributed DoS attacks, a distributed controller is designed. Secondly, by utilizing Lyapunov stability theory, some sufficient conditions for general linear MASs to achieve the secure containment control are obtained. Furthermore, it proves that Zeno behavior can be effectively eliminated. Finally, a simulation example is provided to verify the effectiveness of the proposed control protocol.

关键词： Multi-Agent Systems(MASs) Distributed Denial of Service(DoS) Attacks Event-Triggered Containment Control

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中国现代应用药学 2014年第10期31卷 1207-1212页

作者：和素娜杨晖段冷昕李艳王建刚河南科技大学医学院河南洛阳471003

目的制备利培酮纳米混悬原位凝胶剂并考察其体外释放行为。方法采用反溶剂沉淀法,以粒径为指标,药物浓度(A)、二十二碳六烯酸浓度(B)、水相与油相的比例(C)及搅拌速度(D)为因素,采用正交设计法优化利培酮纳米混悬剂的处方及工艺;进一步... 详细信息

目的制备利培酮纳米混悬原位凝胶剂并考察其体外释放行为。方法采用反溶剂沉淀法,以粒径为指标,药物浓度(A)、二十二碳六烯酸浓度(B)、水相与油相的比例(C)及搅拌速度(D)为因素,采用正交设计法优化利培酮纳米混悬剂的处方及工艺;进一步制备利培酮纳米混悬原位凝胶剂并考察其体外释药行为。结果优化处方及工艺为:A 5 mg·mL-1,B 10 mg·mL-1,C 1∶1,D 600 r·min-1,所制备利培酮纳米混悬剂平均粒径176 nm,PI 0.19,Zeta电位-22.4 mV,利培酮为棒状结晶,在4℃条件下,3个月内稳定性较好,且能够显著增加利培酮的体外溶出速率;含有20%泊洛沙姆407的纳米混悬凝胶剂中,30 d内利培酮累积释放度>90%,符合Higuchi释放模型。结论利培酮纳米混悬处方及工艺简单易行,制剂稳定性较好,进一步制备的原位凝胶剂具有良好的缓释效果。

关键词：利培酮纳米混悬原位凝胶反溶剂沉淀法体外释放

Apoptin原核表达载体的构建及在大肠杆菌中的表达

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西安交通大学学报（医学版） 2008年第5期29卷 496-498,503页

作者：王健生张明鑫段小艺王峥周苏娜张广健王全颖杨广笑西安交通大学医学院第一附属医院肿瘤外科西安交通大学医学院第一附属医院核医学科四川大学华西医院四川成都610041 西安交通大学医学院第一附属医院胸外科陕西西安710061 西安华广生物工程公司陕西西安710025

目的构建Apoptin的原核表达载体,并制备抗原物质Apoptin融合蛋白。方法在获得Apoptin融合基因的基础上,成功构建了Apoptin的高效原核表达载体pET-28a(+)-Apoptin,将该质粒转化至大肠杆菌***21(DE3)受体菌中,以IPTG对其进行诱导表达,聚... 详细信息

目的构建Apoptin的原核表达载体,并制备抗原物质Apoptin融合蛋白。方法在获得Apoptin融合基因的基础上,成功构建了Apoptin的高效原核表达载体pET-28a(+)-Apoptin,将该质粒转化至大肠杆菌***21(DE3)受体菌中,以IPTG对其进行诱导表达,聚丙烯酰胺凝胶电泳分析目的蛋白。结果转化有Apoptin的原核表达载体pET-28a(+)-Apoptin的大肠杆菌***21(DE3)经IPTG诱导后,经SDS-PAGE分析,在相对分子质量约17 000的位置出现目的蛋白条带,大小与Apoptin融合蛋白一致。结论Apoptin原核表达载体pET-28a(+)-Apoptin能够表达出Apoptin融合蛋白,为进一步的Apoptin研究和制备Apoptin抗体奠定了基础。

关键词： Apoptin 原核表达载体 pET-28a(+) 大肠杆菌