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CT guided ^125iodine seed implantation for portal vein tumor thrombus in primary hepatocellular carcinoma

Chinese Medical Journal 2008年第23期121卷 2410-2414页

作者： ZHANG Fu-jun LI Chuan-xing JIAO De-chao ZHANG Nian-hua WU Pei-hong duan guang-feng WU Yue-xia State Key Laboratory of Oncology in South China Department of Imaging and Interventional Radiology Cancer Centre Sun Yat-sen University Guangzhou Guangdong 510060 China Department of Oncology Guangdong Second Provincial Traditional Chinese Medicine Hospital Guangzhou Guangdong 510095 China

Background This study evaluated the clinical application of CT guided ^125iodine implantation in patients with portal vein tumor thrombus in primary hepatocellular carcinoma. Methods The ten patients （9 males and 1 female, aged from 36 to 72 years） with portal vein tumor thrombus accompanying hepatocellular carcinoma had been treated with comprehensive therapy including surgery, transcatheter arterial chemoembolization, radiotherapy ablation, microwave ablation or percutaneous ethanol injection. The average diameter of each tumor thrombus was 21.5 mm × 30.5 mm. Seeds of 30 MBq ^125I were implanted 5 mm apart within the portal vein tumor thrombus. The follow-up after 4 months included enhanced spiral CT. Results CT screening of the tumours indicated that 4 out of 10 patients showed complete response to the therapy, 5 partial response and 1 stable disease. Adverse effects included aggravated abdominal dropsy and temporarily increased transaminase, which were controlled by medical management. Severe complications such as haemorrhage, biliary fistula hepatic abscess, pancreatic fistula and hepatic function failure were not observed. Implanted seeds migrated to lung and left hepatic lobe in 1 case. Conclusion CT guided implantation of ^125iodine seeds, can effectively treat portal vein tumor thrombus accompanying hepatocellular carcinoma with minimal damage and few complications.

关键词： ^125I iodine seed implantation portal vein tumor thrombus brachytherapy primary hepatocellular carcinoma

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Microwave ablation： results in ex vivo and in vivo porcine livers with 2450-MHz cooled-shaft antenna

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Chinese Medical Journal 2011年第20期124卷 3386-3393页

作者： ZHOU Qi JINXing JIAO De-chao ZHANG Fu-jun ZHANG Liang HAN Xin-wei duan guang-feng HAN Jian-jun LI Chuan-xing Department of Hepatobiliary Surgery First Affiliated Hospital Sun Yat-sen University Guangzhou Guangdong 510080 China Department of Interventional Radiology Fourth Hospital of Jilin University Changchun Jilin 130021 China Department of Interventional Radiology First Affiliated Hospital of Zhengzhou University Zhengzhou Henan 450052 China Department of Imaging and Interventional Radiology Cancer Center and State Key Laboratory of Oncology in South China Sun Yat-sen University Guangzhou Guangdong 510060 China

Background Imaging-guided thermal ablation using different energy sources continues to gain favor as a minimally invasive technique for the treatment of primary and metastatic hepatic malignant tumors. This study aimed to evaluate the performance of microwave ablation with 2450-MHz internally cooled-shaft antenna in ex vivo and in vivo porcine livers. Methods All studies were animal care and ethics committee approved. Microwave ablation was performed using a noncooled or cooled-shaft antenna in 23 ex vivo （92 ablations） and eight in vivo （36 ablations） porcine livers. Diameters of the coagulation zone were observed on gross specimens. The coagulation diameters achieved in different microwave ablation parameter groups were compared. Curve estimation analysis was performed to characterize the relationship between applied power and treatment duration and coagulation diameter （including short-axis and long-axis diameter）. Results Coagulation zones were elliptical and an arrowed-shaped carbonization zone around the shaft was observed in all groups. But the antenna track was also coagulated in the noncooled-shaft antenna groups. In ex vivo livers, the short-axis diameter correlated with the power output in a quadratic curve fashion （R2=0.95） by fixing ablation duration to 10 minutes, and correlated with the ablation duration in a logarithmic curve fashion （R2=0.98） by fixing power output to 80 W. The short-axis reached a relative plateau within 25 minutes. In in vivo livers, short-axis diameter correlated with the coagulation duration in a sigmoidal curve fashion （60 W group R2=0.76, 80 W group R2=0.87）, with a relative plateau achieved within 10 minutes for power settings of 60 W and 80 W. Conclusions The internally cooled microwave antenna may be advantageous to minimize collateral damage. The short-axis diameter enlargement has a plateau by fixing power output.

关键词： animals experimental study liver microwave ablation

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Efficient magnetic capture of PE microplastic from water by PEG modified Fe_(3)O_(4)nanoparticles:Performance,kinetics,isotherms and influence factors

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Journal of Environmental Sciences 2025年第1期147卷 677-687页

作者： Yifan Zhang Jingjing duan Ruiqian Liu Evangelos Petropoulos Yanfang feng Lihong Xue Linzhang Yang Shiying He College of Resources and Environmental Sciences Nanjing Agricultural UniversityNanjing 210095China Key Laboratory of Agro-Environment in Downstream of Yangze Plain Ministry of Agriculture and Rural AffairsInstitute of Agricultural Resources and EnvironmentJiangsu Academy of Agricultural SciencesNanjing 210014China School of Engineering Newcastle UniversityNewcastle upon Tyne NE17RUUK Stantec UK Newcastle upon Tyne NE13DYUK

Due to their resistance to degradation,wide distribution,easy diffusion and potential uptake by organisms,microplastics(MPs)pollution has become a major environmental *** this study,PEG-modified Fe_(3)O_(4)magnetic nanoparticles demonstrated superior adsorption efficiency against polyethylene(PE)microspheres compared to other adsorbents(bare Fe_(3)O_(4),PEI/Fe_(3)O_(4)and CA/Fe_(3)O_(4)).Themaximumadsorption capacity of PEwas found to be 2203 mg/g by adsorption isotherm ***/Fe_(3)O_(4)maintained a high adsorption capacity even at low temperature(5℃,2163 mg/g),while neutral pH was favorable for MP *** presence of anions(Cl^(-),SO_(4)^(2-),HCO_(3)^(-),NO_(3)^(-))and of humic acids inhibited the adsorption of *** is proposed that the adsorption process was mainly driven by intermolecular hydrogen ***,the study demonstrated that PEG/Fe_(3)O_(4)can potentially be used as an efficient control against MPs,thus improving the quality of the aquatic environment and of our water resources.

关键词： Microplastic removal Adsorption Magnetic nanoparticles Wastewater Surface modification

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Encapsulating lipase on the surface of magnetic ZIF-8 nanosphers with mesoporous SiO2 nano-membrane for enhancing catalytic performance

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Chinese Chemical Letters 2025年第2期36卷 279-283页

作者： guang-Xu duan Queting Chen Rui-Rui Shao Hui-Huang Sun Tong Yuan Dong-Hao Zhang College of Pharmaceutical Science Hebei University Affiliated Hospital of Hebei University Key Laboratory of Pharmaceutical Quality Control of Hebei Province College of Pharmaceutical ScienceHebei University Institute of Life Science and Green Development Hebei University

The preparation of immobilized enzyme with excellent performance is one of the difficulties that restrict the application of enzyme catalysis technology. Here, Candida rugosa lipase（CRL） was firstly adsorbed on the surface of magnetic zeolitic imidazolate framework-8（ZIF-8） nanospheres, which was further encapsulated with a mesoporous SiO2nano-membrane formed by tetraethyl orthosilicate（TEOS） polycondensation. Consequently, lipase could be firmly immobilized on carrier surface by physical binding rather than chemical binding, which did not damage the active conformation of enzyme. There were mesopores on the silica nano-membrane, which could improve the accessibility of enzyme and its apparent catalytic activity. Moreover, silica membrane encapsulation could also improve the stability of enzyme, suggesting an effective enzyme immobilization strategy. It showed that TEOS amount and the encapsulation time had significant effects on the thickness of silica membrane and the enzyme activity. The analysis in enzyme activity and protein secondary structure showed that lipase encapsulated in silica membrane retained the active conformation to the greatest extent. Compared with the adsorbed lipase, the encapsulated lipase increased its thermostability by 3 times and resistance to chemical denaturants by 7 times. The relative enzyme activity remained around 80% after 8 repetitions, while the adsorbed lipase only remained at7.3%.

关键词： Encapsulation Enzyme immobilization Lipase activity Mesoporous silica membrane ZIF-8

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Super-high bed sintering for iron ores:variation and optimization of bed resistance

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Journal of Iron and Steel Research International 2025年第1期32卷 40-51页

作者： Liang-ping Xu Lin Xiong Hui-bo Liu Xi-duan Yang Ai-xiang Mao Pei-dun Chen guang-hui Li School of Minerals Processing and Bioengineering Central South UniversityChangsha410083HunanChina Central Research Institute Baosteel Group Co.Ltd.Shanghai201900China Manufacturing Management Department Guangdong Zhongnan Iron and Steel Co.Ltd.Shaoguan512123GuangdongChina Technology and Development Center Shandong Taishan Iron and Steel Group Co.Ltd.Jinan271100ShandongChina

As the bed depth increases,sintering yield increases,but the productivity *** reveal the reasons for the decrease in productivity and explore targeted solutions,the bed resistance of mixtures,wet zone,and combustion zone was analyzed in the *** results showed that the decreased porosity of mixture resulted in the increased bed resistance by 160.56%when the bed depth increased from 600 to 1000 *** improving porosity of 1%by adding loosening bars with optimized size and distribution,the bed resistance decreased,and the productivity increased by 5%.The increase in bed depth increased the thickness of the wet zone from 120 to 680 mm and the resistance from 1.56 to 8.83 *** using a three-stage intensive mixer and pre-adding water for granulation,the moisture of mixture was reduced by 0.6%,and the sintering productivity increased by 4%.Besides,the high bed resistance is mainly caused by the increase in the thickness of the combustion zone from 31.9 to 132.7 mm,and the bed resistance increased from 0.70 to 5.62 *** bed resistance of the combustion zone at 900 mm was increased by 90.51%compared to 700 *** optimization of the distribution of coke breeze,the thickness of combustion zone at the lower layer decreased from 132.7 to 106.84 mm and permeability improved significantly.

关键词： Super-high bed sintering Bed resistance Permeability Productivity Wet zone Combustion zone

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Distribution and mapping of temperate savanna in the sandy lands of eastern China

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Science China Earth Sciences 2025年第1期68卷 128-141页

作者： Xiaoya LI feng WANG Tao duan Kaijie YANG Bin YANG Chunmei WANG Xin TIAN Qi LU Institute of Ecological Conservation and Restoration Institute of Desertification StudiesChinese Academy of ForestryBeijing100091China Institute of Desertification Institute of Desertification StudiesChinese Academy of ForestryBeijing100091China Institute of Great Green Wall Bayan Nur015200China Satellite Application Centre for Ecology and Environment MEEBeijing100094China Institute of Microelectronics Chinese Academy of SciencesBeijing100029China Aerospace Information Research Institute Chinese Academy of SciencesBeijing100094China Institute of Forest Resource Information Techniques Chinese Academy of ForestryBeijing100091China

Savannas are distributed globally across various *** perform a significant socioeconomic role in regulating net primary productivity and the terrestrial carbon *** to the high spatial heterogeneity induced by the mixed distribution of trees and grasses,current global land-cover classification maps often classify savannas as forests or grasslands Temperate savannas in China cover a vast area,yet their spatial patterns and extent remain poorly *** study developed a novel remote sensing temperate savannas mapping method by integrating very high-resolution(VHR)unmanned aerial vehicle(UAV)and GF-6 satellite imagery based on the vegetation structure characteristics of temperate savannas using the FAO definition of *** and validation datasets were collected from VHR UAV imagery covering the main temperate savannah types with a ground area of 1818 *** fractional woody vegetation cover(FWVC)and fractional herbaceous vegetation cover(FHVC)in temperate savannas were estimated by integrating Classification and Regression Tree and Random Forest *** current distribution of temperate savannas in the Horqin and Otindag Sandy Lands of Eastern China was mapped to a unit area of 0.5 *** root-mean-square error(RMSE)values for the FWVC and FHVC models were 10.69%and 11.67%,and the R^(2)values were 0.66 and 0.63,*** assessment indicated that the new temperate savanna map had high identification accuracy,with a Kappa coefficient of 0.70,overall accuracy of 0.88,and average accuracy of *** savannas in the sandy lands of eastern China were primarily distributed in the northern Horqin Sandy Land the central and eastern regions of the Otindag Sandy Land,and the transition zone from the southern slopes of the Greater Khingan Mountains to the plains,covering a total area of 3.27×10^(6)*** main savannah types were elm,oak/maple,and shrub *** savannas were widely distributed in the Otindag Sandy Land a

关键词： Temperate savanna UAV imagery GF-6 Fractional woody vegetation cover Fractional herbaceous vegetation cover Machine learning

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Zircon U-Pb dating of the Shazibu Pluton in the Guocheng gold belt, Jiaolai Basin, Shandong Province: Implications for metallogeny of the Jiaodong gold province

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China Geology 2025年第1期8卷 230-232页

作者： Yuan-yuan feng Ya-dong Li An-kai Geng Liu-an duan Da-dou Li No.1 Geological Team of Shandong Province Bureau of Geology and Mineral Resources Jinan 250100China Yantai Geological Survey Center of Coastal Zone China Geological SurveyYantai 264004China

*** Three stages of Mesozoic magmatic activity have been identified in the Jiaodong area,namely early magmatic emplacement,the magmatic emplacement prior to mineralization,and magmatic activity post-mineralization,fro... 详细信息

关键词： dating belt mineralization

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上海市中心城区二级公立医院资产负债及相关因素分析

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中国卫生经济 2015年第3期34卷 68-70页

作者：段光锋田文华第二军医大学卫生勤务学系卫生事业管理学教研室上海200433

目的:探讨城市二级公立医院资产负债现状、趋势及其相关因素。方法:以上海市中心城区的20家二级公立医院为研究对象,对其资产负债率进行统计描述,并利用多元回归分析资产负债率的相关因素。结果:2002—2012年上海市中心城区二级公立医... 详细信息

目的:探讨城市二级公立医院资产负债现状、趋势及其相关因素。方法:以上海市中心城区的20家二级公立医院为研究对象,对其资产负债率进行统计描述,并利用多元回归分析资产负债率的相关因素。结果:2002—2012年上海市中心城区二级公立医院负债呈逐年增长趋势,资产负债率在20.30%~33.56%之间,开放床位数和资产周转率的回归系数具有统计学意义。结论:上海市中心城区二级公立医院资产负债率呈现先下降后上升的趋势,低于同期全国公立医院负债水平;资产负债率与开放床位数呈负相关,与资产周转率呈正相关。

关键词：二级医院公立医院资产负债上海

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退火处理对ITO表面特性及有机发光器件性能的影响

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液晶与显示 2005年第6期20卷 498-502页

作者：仲飞刘彭义段光凤暨南大学物理系广东广州510632

为了改善有机发光器件(OLEDs)的性能,在0～600 ℃不同温度下对ITO透明导电玻璃进行了退火处理.SEM观察到随退火温度的升高,ITO表面粗糙度增加;四探针电阻测试结果显示,在300 ℃以上温度退火后ITO表面电阻率有明显增加.用退火前后的ITO... 详细信息

为了改善有机发光器件(OLEDs)的性能,在0～600 ℃不同温度下对ITO透明导电玻璃进行了退火处理.SEM观察到随退火温度的升高,ITO表面粗糙度增加;四探针电阻测试结果显示,在300 ℃以上温度退火后ITO表面电阻率有明显增加.用退火前后的ITO玻璃作为阳极制备了OLEDs,器件结构为ITO/TPD/Alq3/Al,比较器件的电流密度-电压特性曲线测试结果表明,ITO薄膜的热处理温度对OLEDs性能有显著的影响.

关键词： ITO 有机发光器件退火表面处理性能

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Soil colloids can significantly enhance spreading of polybromodiphenyl ethers in groundwater by serving as an effective carrier

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Journal of Environmental Sciences 2025年第1期147卷 93-100页

作者： Lin duan Min Li Jiameng Liu Wei Chen College of Environmental Science and Engineering Ministry of Education Key Laboratory of Pollution Processes and Environmental CriteriaTianjin Key Laboratory of Environmental Remediation and Pollution ControlNankai UniversityTianjin 300350China

Polybromodiphenyl ethers(PBDEs),the widely used flame retardants,are common contaminants in surface soils at e-waste recycling *** association of PBDEs with soil colloids has been observed,indicating the potential risk to groundwater due to colloid-facilitated ***,the extent to which soil colloidsmay enhance the spreading of PBDEs in groundwater is largely ***,we report the co-transport of decabromodiphenyl ester(BDE-209)and soil colloids in saturated porous *** colloids released froma soil sample collected at an e-waste recycling site in Tianjin,China,contain high concentration of PBDEs,with BDE-209 being the most abundant conger(320±30 mg/kg).The colloids exhibit relatively high mobility in saturated sand columns,under conditions commonly observed in groundwater ***,under all the tested conditions(i.e.,varying flow velocity,pH,ionic species and ionic strength),the mass of eluted BDE-209 correlates linearly with that of eluted soil colloids,even though the mobility of the colloids varies markedly depending on the specific hydrodynamic and solution chemistry conditions ***,the mass of BDE-209 retained in the columns also correlates strongly with themass of retained ***,the PBDEs remain bound to soil colloids during transport in porous *** in this study indicate that soil colloidsmay significantly promote the transport of PBDEs in groundwater by serving as an effective *** might be the reason why the highly insoluble and adsorptive PBDEs are found in groundwater at some PBDE-contaminated sites.

关键词： Polybromodiphenyl ethers Soil colloids E-waste recycling sites Groundwater Facilitated transport

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