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Predictive value of neutrophil-to-lymphocyte ratio in coronary chronic total occlusion patients

Journal of Geriatric Cardiology 2024年第5期21卷 542-549页

作者： Qian LI Yue YU ya-Qiong ZHOU Yi ZHAO Jin WU Yuan-Jing WU Bin du Pei-Jian WANG Tao ZHENG Department of Cardiovascular Medicine the First Affiliated Hospital of Xi’an Jiaotong UniversityXi’anChina Department of Cardiology First Affiliated Hospital of Chengdu Medical CollegeChengduChina Department of Neurology the First Affiliated Hospital of Xi’an Jiaotong UniversityXi’anChina

BACKGROUND The neutrophil to lymphocyte ratio(NLR)has been reported as a novel predictor for atherosclerosis and car-diovascular *** study aimed to determine the effects of NLR on long-term clinical outcomes of chronic total occlusion(CTO)*** A total of 670 patients with CTO who met the inclusion criteria were included at the end of the follow-up *** were divided into tertiles according to their baseline NLR levels at admission:low(n=223),intermediate(n=223),and high(n=224).The incidence of major adverse cardiac events(MACEs)during the follow-up period,including all-cause death,nonfatal myocardial infarction(MI),or ischemia-driven revascularization,were compared among the three *** Major adverse cardiac events were observed in 27 patients(12.1%)in the low tertile,40(17.9%)in the intermediate tertile,and 61(27.2%)in the high NLR tertile(P<0.001).Kaplan-Meier analysis demonstrated a significantly higher incidence of MACE,ischemia-driven coronary revascularization,non-fatal MI,and mortality in patients within the high tertile than those in the low and intermediate groups(all P<0.001).Multivariable COX regression analysis showed that the high tertile of baseline NLR level showed a strong association with the risk of MACE(hazard ratio[HR]=2.21;95%confidence interval[CI]:1.21-4.03;P=0.009),ischemia-driven coronary revascularization(HR=3.19;95%CI:1.56-6.52;P=0.001),MI(HR=2.61;95%CI:1.35-5.03;P=0.043)and mortality(HR=3.78;95%CI:1.65-8.77;P=0.001).CONCLUSION Our findings suggest that NLR is an inexpensive and readily available biomarker that can independently pre-dict cardiovascular risk in patients with CTO.

关键词： patients coronary occlusion

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A Practical Regular LDPC Coded Scheme for Physical-Layer Information Security

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China Communications 2024年第5期21卷 190-201页

作者： du Junyi CETC Key Laboratory of Avionic Information System Southwest China Institute of Electronic TechnologyChengdu 610036China

In this paper,we aim to design a practical low complexity low-density parity-check(LDPC)coded scheme to build a secure open channel and protect information from *** this end,we first propose a punctured LDPC coded scheme,where the information bits in a codeword are punctured and only the parity check bits are transmitted to the *** further propose a notion of check node type distribution and derive multi-edge type extrinsic information transfer functions to estimate the security performance,instead of the well-known weak metric bit error *** optimize the check node type distribution in terms of the signal-to-noise ratio(SNR)gap and modify the progressive edge growth algorithm to design finite-length *** results show that our proposed scheme can achieve a lower computational complexity and a smaller security gap,compared to the existing scrambling and puncturing schemes.

关键词： extrinsic information transfer function physical layer scheme secure open channel security gap

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Research progress in CALPHAD assisted metal additive manufacturing

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China Foundry 2024年第4期21卷 295-310页

作者： ya-qing Hou Xiao-qun Li Wei-dong Cai Qing Chen Wei-ce Gao du-peng He Xue-hui Chen Hang Su China Iron&Steel Research Institute Group Beijing 100081China Thermo-Calc Software AB SolnaSE-169Sweden KTH Royal Institute of Technology StockholmSE-100Sweden Central Iron and Steel Research Institute Beijing 100081China

Metal additive manufacturing(MAM)technology has experienced rapid development in recent *** both equipment and materials progress towards increased maturity and commercialization,material metallurgy technology based on high energy sources has become a key factor influencing the future development of *** calculation of phase diagrams(CALPHAD)is an essential method and tool for constructing multi-component phase diagrams by employing experimental phase diagrams and Gibbs free energy models of simple *** combining with the element mobility data and non-equilibrium phase transition model,it has been widely used in the analysis of traditional metal *** development of CALPHAD application technology for MAM is focused on the compositional design of printable materials,the reduction of metallurgical imperfections,and the control of microstructural *** endeavor carries considerable theoretical and practical *** paper summarizes the important achievements of CALPHAD in additive manufacturing(AM)technology in recent years,including material design,process parameter optimization,microstructure evolution simulation,and properties ***,the limitations of applying CALPHAD technology to MAM technology are discussed,along with prospective research directions.

关键词： metal additive manufacturing CALPHAD integrated computational material engineering powder bed fusion material design microstructure simulation

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The DNA damage repair complex MoMMS21-MoSMC5 is required for infection-related development and pathogenicity of Magnaporthe oryzae

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Journal of Integrative Agriculture 2024年第6期23卷 1956-1966页

作者： Yue Jiang Rong Wang Lili du Xueyu Wang Xi Zhang Pengfei Qi Qianfei Wu Baoyi Peng Zonghua Wang Mo Wang ya Li State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops Fujian Agriculture and Forestry UniversityFuzhou 350002China State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan Yunnan Agricultural UniversityKunming 650201China Fujian Universities Key Laboratory for Plant-Microbe Interaction Fujian Agriculture and Forestry UniversityFuzhou 350002China Ministerial and Provincial Joint Innovation Centre for Safety Production of Cross-Strait Crops Minjiang UniversityFuzhou 350108China Fujian Key Laboratory for Monitoring and Integrated Management of Crop Pests Fuzhou 350003China

The conserved DNA damage repair complex,MMS21-SMC5/6(Methyl methane sulfonate 21-Structural maintenance of chromosomes 5/6),has been extensively studied in yeast,animals,and ***,its role in phytopathogenic fungi,particularly in the highly destructive rice blast fungus Magnaporthe oryzae,remains *** this study,we functionally characterized the homologues of this complex,MoMMS21 and MoSMC5,in *** first demonstrated the importance of DNA damage repair in *** by showing that the DNA damage inducer phleomycin inhibited vegetative growth,infection-related development and pathogenicity in this ***,we discovered that MoMMS21 and MoSMC5 interacted in the nuclei,suggesting that they also function as a complex in *** deletion experiments revealed that both MoMMS21 and MoSMC5 are required for infection-related development and pathogenicity in ***,while only MoMMS21 deletion affected growth and sensitivity to phleomycin,indicating its specific involvement in DNA damage ***,our results provide insights into the roles of MoMMS21 and MoSMC5 in ***,highlighting their functions beyond DNA damage repair.

关键词： Magnaporthe oryzae MMS21 SMC5 DNA damage repair pathogenicity

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In-phase and out-of-phase spin pumping effects in Py/Ru/Pysynthetic antiferromagnetic structures

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Chinese Physics B 2024年第9期33卷 541-545页

作者： Zhaocong Huang Xuejian Tang Qian Chen Wei Jiang Qingjie Guo Milad Jalali Jun du ya Zhai Key Laboratory of Quantum Materials and Devices of Ministry of Education School of PhysicsSoutheast UniversityNanjing 211189China National Laboratory of Solid Microstructures Nanjing UniversityNanjing 210093China

The spin pumping effect in magnetic heterostructures and multilayers is a highly effective method for the generationand transmission of spin currents. In the increasingly prominent synthetic antiferromagnetic structures, the two ferromagneticlayers demonstrate in-phase and out-of-phase states, corresponding to acoustic and optical precession modes. Withinthis context, our study explores the spin pumping effect in Py/Ru/Py synthetic antiferromagnetic structures across differentmodes. The heightened magnetic damping resulting from the spin pumping effect in the in-phase state initially decreaseswith increasing Py thickness before stabilizing. Conversely, in the out-of-phase state, the amplified damping exceeds thatof the in-phase state, suggesting a greater spin relaxation within this configuration, which demonstrates sensitivity to alterationsin static exchange interactions. These findings contribute to advancing the application of synthetic antiferromagneticstructures in magnonic devices.

关键词： spin pumping spin transmission synthetic antiferromagnetic structures spin dynamics

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Mimicking Mytilus edulis foot protein:A versatile strategy for robust biomedical coatings

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The Innovation 2024年第5期5卷 73-82,72页

作者： Zeyu du Feng Qiao Liping Tong Wentai Zhang Xiaohui Mou Xin Zhao Manfred FMaitz Huaiyu Wang nan Huang Zhilu yang School of Materials Science and Engineering Department of CardiologyThird People’s Hospital of Chengdu Affiliated with Southwest Jiaotong UniversitySouthwest Jiaotong UniversityChengdu 610031China Dongguan Key Laboratory of Smart Biomaterials and Regenerative Medicine The Tenth Affiliated Hospital of Southern Medical UniversityDongguan 523059China Institute of Biomedicine and Biotechnology Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China Department of Biomedical Engineering The Hong Kong Polytechnic UniversityHung HomHong KongChina Max Bergmann Center of Biomaterials Dresden Leibniz Institute of Polymer Research DresdenHohe Strasse 601069 DresdenGermany The Key Laboratory of Biomedical Imaging Science and System Chinese Academy of SciencesShenzhen 518055China GuangZhou nanchuang Mount Everest Company for Medical Science and Technology Guangzhou 510670China

Universal coatings with versatile surface adhesion,good mechanochemical robustness,and the capacity for secondary modification are of great scientific ***,incorporating these advantages into a system is still a great ***,we report a series of catechol-decorated polyallylamines(CPAs),denoted as pseudo-Mytilus edulis foot protein 5(pseudoMefp-5),that mimic not only the catechol and amine groups but also the backbone of *** can fabricate highly adhesive,robust,multifunctional polyCPA(PCPA)coatings based on synergetic catechol-polyamine chemistry as universal building *** to the interpenetrating entangled network architectures,these coatings exhibit high chemical robustness against harsh conditions(HCl,pH 1;NaOH,pH 14;H2O2,30%),good mechanical robustness,and wear *** addition,PCPA coatings provide abundant grafting sites,enabling the fabrication of various functional surfaces through secondary ***,the versatility,multifaceted robustness,and scalability of PCPA coatings indicate their great potential for surface engineering,especially for withstanding harsh conditions in multipurpose biomedical applications.

关键词： wear catechol versatile

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Transformer and GAN-Based Super-Resolution Reconstruction Network for Medical Images

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Tsinghua Science and Technology 2024年第1期29卷 197-206页

作者： Weizhi du Shihao Tian Arts&Sciences College Washington University in St.LouisSt.LouisMO 63130USA Department of Electric and Computing Engineering Cornell UniversityIthacaNY 14850USA

Super-resolution reconstruction in medical imaging has become more demanding due to the necessity of obtaining high-quality images with minimal radiation dose,such as in low-field magnetic resonance imaging(MRI).However,image super-resolution reconstruction remains a difficult task because of the complexity and high textual requirements for diagnosis *** this paper,we offer a deep learning based strategy for reconstructing medical images from low resolutions utilizing Transformer and generative adversarial networks(T-GANs).The integrated system can extract more precise texture information and focus more on important locations through global image matching after successfully inserting Transformer into the generative adversarial network for picture ***,we weighted the combination of content loss,adversarial loss,and adversarial feature loss as the final multi-task loss function during the training of our proposed model *** comparison to established measures like peak signal-to-noise ratio(PSNR)and structural similarity index measure(SSIM),our suggested T-GAN achieves optimal performance and recovers more texture features in super-resolution reconstruction of MRI scanned images of the knees and belly.

关键词： super-resolution image reconstruction Transformer generative adversarial network(GAN)

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Energy consumption simulations of rural residential buildings considering differences in energy use behavior among family members

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Building Simulation 2024年第8期17卷 1335-1358页

作者： Xi Luo Lina du School of Building Services Science and Engineering Xi'an University of Architecture and Technology(XAUAT)Xi'an 710055China State Key Laboratory of Green Building Xi'an 710055China

The“average occupant”methodology is widely used in energy consumption simulations of residential buildings;however,it fails to consider the differences in energy use behavior among family *** on a field survey on the Central Shaanxi Plain,to identify the energy use behavior patterns of typical families,a stochastic energy use behavior model considering differences in energy use behavior among family members was proposed,to improve the accuracy of energy consumption simulations of residential *** results indicated that the surveyed rural families could be classified into the following four types depending on specific energy use behavior patterns:families of one elderly couple,families of one middle-aged couple,families of one elderly couple and one child,and families of one couple and one ***,on typical summer days,the results of daily building energy consumption simulation obtained by the“average occupant”methodology were 25.39%and 28%lower than the simulation results obtained by the model proposed in this study for families of one elderly couple and families of one middle-aged couple,and 13.05%and 23.05%higher for families of one elderly couple and one child,and families of one couple and one *** typical winter days,for the four types of families,the results of daily building energy consumption simulation obtained by the“average occupant”methodology were 21.69%,10.84%,1.21%,and 8.39%lower than the simulation results obtained by the model proposed in this study,respectively.

关键词： typical energy use behavior pattern differences in occupant behavior building energy consumption simulation stochastic energy use behavior simulation

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Reversible Mn^(2+)/Mn^(4+)double-electron redox in P3-type layer-structured sodium-ion cathode

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Journal of Energy Chemistry 2024年第2期89卷 79-88,I0004页

作者： Jie Zeng Jian Bao ya Zhang Xun-Lu Li Cui Ma Rui-Jie Luo Chong-Yu du Xuan Xu Zhe Mei Zhe Qian Yong-Ning Zhou Department of Materials Science Fudan UniversityShanghai 200433China Shanghai Xuanyi New Energy Development Co. LtdShanghai 201800China Global Institute of Future Technology Shanghai Jiao Tong UniversityShanghai 200240China

The balance between cationic redox and oxygen redox in layer-structured cathode materials is an important issue for sodium batteries to obtain high energy density and considerable cycle *** redox can contribute extra capacity to increase energy density,but results in lattice instability and capacity fading caused by lattice oxygen gliding and oxygen *** this work,reversible Mn^(2+)/Mn^(4+)redox is realized in a P3-Na_(0.65)Li_(0.2)Co_(0.05)Mn_(0.75)O_(2)cathode material with high specific capacity and structure stability via Co *** contribution of oxygen redox is suppressed significantly by reversible Mn^(2+)/Mn^(4+)redox without sacrificing capacity,thus reducing lattice oxygen release and improving the structure *** X-ray techniques reveal that P3 phase is well maintained in a wide voltage window of 1.5-4.5 V ***^(+)/Na even at 10 C and after long-term *** is disclosed that charge compensation from Co/Mn-ions contributes to the voltage region below 4.2 V and O-ions contribute to the whole voltage *** synergistic contributions of Mn^(2+)/Mn^(4+),Co^(2+)/Co^(3+),and O^(2-)/(O_n)^(2-)redox in P3-Na_(0.65)Li_(0.2)Co_(0.05)Mn_(0.75)O_(2)lead to a high reversible capacity of 215.0 m A h g^(-1)at 0.1 C with considerable cycle *** strategy opens up new opportunities for the design of high capacity cathode materials for rechargeable batteries.

关键词： Sodium batteries Cathode materials Layered structure Co substitution

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PSRDP:A Parallel Processing Method for Pulsar Baseband Data

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Research in Astronomy and Astrophysics 2024年第1期24卷 300-310页

作者： ya-Zhou Zhang Hai-Long Zhang Jie Wang Xin-Chen Ye Shuang-Qiang Wang Xu du Han Wu Ting Zhang Shao-Cong Guo Meng Zhang Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Radio Astronomy Chinese Academy of SciencesNanjing 210008China National Astronomical Data Center Beijing 100101China Southeast University Nanjing 211189China School of Cyber Science and Engineering Qufu Normal UniversityQufu 273165China

To address the problem of real-time processing of ultra-wide bandwidth pulsar baseband data,we designed and implemented a pulsar baseband data processing algorithm(PSRDP)based on GPU parallel computing *** can perform operations such as baseband data unpacking,channel separation,coherent dedispersion,Stokes detection,phase and folding period prediction,and folding integration in GPU *** tested the algorithm using the J0437-4715 pulsar baseband data generated by the CASPSR and Medusa backends of the Parkes,and the J0332+5434 pulsar baseband data generated by the self-developed backend of the nan Shan Radio *** obtained the pulse profiles of each baseband *** experimental analysis,we have found that the pulse profiles generated by the PSRDP algorithm in this paper are essentially consistent with the processing results of Digital Signal Processing Software for Pulsar Astronomy(DSPSR),which verified the effectiveness of the PSRDP ***,using the same baseband data,we compared the processing speed of PSRDP with DSPSR,and the results showed that PSRDP was not slower than DSPSR in terms of *** theoretical and technical experience gained from the PSRDP algorithm research in this article lays a technical foundation for the real-time processing of QTT(Qi Tai radio Telescope)ultra-wide bandwidth pulsar baseband data.

关键词： (stars:)pulsars:general methods:data analysis techniques:miscellaneous

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