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Global status and trends of metabolomics in diabetes: A literature visualization knowledge graph study

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World Journal of Diabetes 2024年第5期15卷 1021-1044页

作者： hong Li Liu Li Qiu-Qing Huang Si-Yao Yang Jun-Ju Zou Fan Xiao Qin xiang Xiu Liu Rong Yu College of Chinese Medicine Hunan University of Chinese MedicineChangsha 410208Hunan ProvinceChina College of International Education Hunan University of Chinese MedicineChangsha 410208Hunan ProvinceChina Department of Science and Technology Hunan University of Chinese MedicineChangsha 410208Hunan ProvinceChina Hunan Key Laboratory of TCM Prescription and Syndromes Translational Medicine Hunan University of Chinese MedicineChangsha 410208Hunan ProvinceChina College of Graduate Hunan University of Chinese MedicineHunan ChangshaHunan ProvinceChina

BACKGROUND Diabetes is a metabolic disease characterized by hyperglycemia,which has increased the global medical burden and is also the main cause of death in most *** To understand the knowledge structure of global development status,research focus,and future trend of the relationship between diabetes and metabolomics in the past 20 *** The articles about the relationship between diabetes and metabolomics in the Web of Science Core Collection were retrieved from 2002 to October 23,2023,and the relevant information was analyzed using CiteSpace6.2.2R(CiteSpace),VOSviewer6.1.18(VOSviewer),and Bibliometrix software under R *** A total of 3123 publications were included from 2002 to *** the past two decades,the number of publications and citations in this field has continued to *** United States,China,Germany,the United Kingdom,and other relevant funds,institutions,and authors have significantly contributed to this *** Reports and PLoS One are the journals with the most publications and the most *** keyword co-occurrence and cluster analysis,the closely related keywords are"insulin resistance","risk","obesity","oxidative stress","metabolomics","metabolites"and"biomarkers".Keyword clustering included cardiovascular disease,gut microbiota,metabonomics,diabetic nephropathy,molecular docking,gestational diabetes mellitus,oxidative stress,and insulin *** detection analysis of keyword depicted that"Gene","microbiota","validation","kidney disease","antioxidant activity","untargeted metabolomics","management",and"accumulation"are knowledge frontiers in recent *** The relationship between metabolomics and diabetes is receiving extensive *** nephropathy,diabetic cardiovascular disease,and kidney disease are key diseases for future research in this *** microbiota,molecular docking,and untargeted metabolomics are key research directions in the *** a

关键词： Diabetes Metabolomics Bibliometric CiteSpace VOSviewer

Three-dimensional interconnected graphene network-based high-performance air electrode for rechargeable zinc‒air batteries

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SusMat 2024年第3期4卷 192-203页

作者： Jia-Xing An Yu Meng hong-Bo Zhang Yuanzhi Zhu Xiaohua Yu Ju Rong Peng-xiang Hou Chang Liu Hui-Ming Cheng Jin-Cheng Li Faculty of Chemical Engineering Yunnan Provincial Key Laboratory of Energy Saving in Phosphorus Chemical Engineering and New Phosphorus MaterialsKunming University of Science and TechnologyKunmingChina Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyangChina Faculty of Materials Science and Engineering Kunming University of Science and TechnologyKunmingChina

Although zinc-air batteries(ZABs)are regarded as one of the most prospective energy storage devices,their practical application has been restricted by poor air electrode ***,we developed a free-standing air electrode that is fabricated on the basis of a multifunctional three-dimensional interconnected graphene ***,a three-dimensional interconnected graphene network with fast mass and electron transport ability,prepared by catalyzing growth of graphene foam on nickel foam and then filling reduced graphene oxide into the pores of graphene foam,is used to anchor iron phthalocyanine molecules with atomic Fe-N_(4)sites for boosting the oxygen reduction during discharging and nanosized FeNi hydroxides for accelerating the oxygen evolution during *** a result,the obtained air electrode exhibited an ultra-small electrocatalytic overpotential of 0.603 V for oxygen reactions,a high peak power density of 220.2mWcm^(-2),and a small and stable charge-discharge voltage gap of 0.70 V at 10mA cm^(-2)after 1136 ***,in situ Raman spectroscopy together with theoretical calculations confirmed that phase transformation of FeNi hydroxides takes place fromα-Ni(OH)_(x)toβ-Ni(OH)_(x)toγ-Ni^((3+δ)+)OOH for the oxygen evolution reaction and Ni is the active center while Fe enhances the activity of Ni active sites.

关键词： in situ Raman interconnected graphene network iron phthalocyanine NiFe hydroxide zinc‒air battery

对投资者权益保护的监管问题研究——基于行为法经济学的视角

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企业技术开发 2008年第10期27卷 56-58页

作者：杜湘红王菁湖南师范大学商学院湖南长沙410081 湖南工业大学经济管理学院湖南株洲412008

在社会主义市场经济体系中,中小投资者与经营者和控股股东相比处于弱势地位,需要对其权益进行保护,在法律不完备与不健全的背景下,投资者权益的保护在很大程度上依赖于行政监管的有效性。文章引入行为经济学的观点,认为只有认识到中小... 详细信息

在社会主义市场经济体系中,中小投资者与经营者和控股股东相比处于弱势地位,需要对其权益进行保护,在法律不完备与不健全的背景下,投资者权益的保护在很大程度上依赖于行政监管的有效性。文章引入行为经济学的观点,认为只有认识到中小投资者和监管者存在的诸如过度自信,反应不足等行为偏差,并且在经济活动中进行有效纠正才可能更好地保护投资者权益,同时提出了应加强对投资者的教育以及改善行政监管的有效措施。

关键词：投资者监管者行为法经济学

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抗毒合剂提取工艺的优选

中国药学杂志 2016年第14期51卷 1252-1255页

作者：杜向红张伟李国峰刘伟李鹏远陈宁杜云锋河南省人民医院郑州450008 河南中医学院分析测试中心郑州450046

目的运用L9(34)正交试验设计,考察各影响因素显著性,筛选抗毒合剂的最佳制备工艺。方法应用正交试验法考察加水量、提取时间和提取次数对抗毒合剂提取工艺的影响,通过高效液相色谱法测定绿原酸的含量和浸膏得率,用综合加权评分法对提取... 详细信息

目的运用L9(34)正交试验设计,考察各影响因素显著性,筛选抗毒合剂的最佳制备工艺。方法应用正交试验法考察加水量、提取时间和提取次数对抗毒合剂提取工艺的影响,通过高效液相色谱法测定绿原酸的含量和浸膏得率,用综合加权评分法对提取工艺进行评价,并进行验证。结果抗毒合剂的最佳水提醇沉工艺为A3B2C2,即饮片回流提取3 h,加10倍量的水,提取2次。结论经正交设计优化的抗毒合剂的制备工艺合理可行,该方法简便、精度高、重现性好。

关键词：抗毒合剂提取工艺最佳工艺

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基于校企深度合作的专硕培养模式探索

企业技术开发 2015年第8期34卷 65-66页

作者：张涛杜湘红中南大学信息科学与工程学院湖南长沙410083 湖南师范大学商学院湖南长沙410081

理论与实践证明,校企合作是培养创新应用人才最重要的途径。基于校企深度合作积极探索产学研结合的培养模式,推动高等教育与就业的关联性建设,全面提高学生的创新能力与职业能力,是目前专硕培养的关键问题,也是我国专业学位研究生教育... 详细信息

理论与实践证明,校企合作是培养创新应用人才最重要的途径。基于校企深度合作积极探索产学研结合的培养模式,推动高等教育与就业的关联性建设,全面提高学生的创新能力与职业能力,是目前专硕培养的关键问题,也是我国专业学位研究生教育改革和发展的重要内容,是新时期高素质技术与技能应用型人才培养的必由之路。

关键词：校企深度合作培养模式专业学位硕士

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长株潭城市群交通运输节能降碳初探

科教文汇 2016年第34期 187-189页

作者：龙村杜湘红湖南师范大学附属中学湖南长沙410006 湖南师范大学湖南长沙410006

新型城市化进程伴随交通运输行业的飞速发展,随之带来能源消耗和碳排放居高不下,近年交通运输行业节能降碳面临着艰巨的挑战。作为国家两型社会改革试验区,长株潭地区大力发展绿色交通,建设长株潭地区节能和低碳城市群意义重大。本文研... 详细信息

新型城市化进程伴随交通运输行业的飞速发展,随之带来能源消耗和碳排放居高不下,近年交通运输行业节能降碳面临着艰巨的挑战。作为国家两型社会改革试验区,长株潭地区大力发展绿色交通,建设长株潭地区节能和低碳城市群意义重大。本文研究表明长株潭区域构建节能低碳型交通系统具备较为优越的地理环境和基础设施,新能源车辆应用推广等降碳举措取得了一定效果。但能源消耗和碳排放仍然居于较高水平,节能低碳交通系统建设任重道远。政府应高度重视交通运输行业节能降碳问题,推广绿色交通工具,引导人们选择低碳出行方式。

关键词：交通运输两型社会节能降碳

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基于利益相关者理论的校企深度合作问题探讨

企业技术开发 2015年第12期34卷 74-75,78页

作者：张涛杜湘红中南大学信息科学与工程学院湖南长沙410083 湖南师范大学商学院湖南长沙410081

促进高等教育可持续和谐发展,从利益相关者的角度探析提升校企合作人才培养问题,对实现高等教育培养模式的组织创新具有一定的理论和现实意义。校企合作培养"卓越人才"要想取得实质性的效果,需要各利益相关者密切配合,建立以政府为主导... 详细信息

促进高等教育可持续和谐发展,从利益相关者的角度探析提升校企合作人才培养问题,对实现高等教育培养模式的组织创新具有一定的理论和现实意义。校企合作培养"卓越人才"要想取得实质性的效果,需要各利益相关者密切配合,建立以政府为主导,高校、学生、企业和社会各方协同参与的保障机制。

关键词：校企合作利益相关者利益诉求

Cardiac Piezo1 Exacerbates Lethal Ventricular Arrhythmogenesis by Linking Mechanical Stress with Ca^(2+) Handling After Myocardial Infarction

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Research 2024年第1期2023卷 583-594页

作者： Sheng-an Su Yuhao Zhang Wudi Li Yutao Xi Yunrui Lu Jian Shen Yuankun Ma Yaping Wang Yimin Shen Lan Xie hong Ma Yao Xie Meixiang xiang Department of Cardiology Cardiovascular Key Laboratory of Zhejiang ProvinceThe Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009China Department of Endocrinology The Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009China Texas Heart Institute HoustonTX 77030USA

Ventricular arrhythmogenesis is a key cause of sudden cardiac death following myocardial infarction(MI).Accumulating data show that ischemia,sympathetic activation,and inflammation contribute to ***,the role and mechanisms of abnormal mechanical stress in ventricular arrhythmia following MI remain *** aimed to examine the impact of increased mechanical stress and identify the role of the key sensor Piezo1 in ventricular arrhythmogenesis in *** with increased ventricular pressure,Piezo1,as a newly recognized mechano-sensitive cation channel,was the most up-regulated mechanosensor in the myocardium of patients with advanced heart ***1 was mainly located at the intercalated discs and T-tubules of cardiomyocytes,which are responsible for intracellular calcium homeostasis and intercellular communication.

关键词： ventricular homeostasis Ventricular

Classification of spin Hall effect in two-dimensional systems

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Frontiers of physics 2024年第3期19卷 103-114页

作者： Longjun xiang Fuming Xu Luyang Wang Jian Wang College of Physics and Optoelectronic Engineering Shenzhen UniversityShenzhen 518060China Quantum Science Center of Guangdong-hongkong-Macao Greater Bay Area(Guangdong) Shenzhen 518045China Department of Physics The University of Hong KongPokfulam RoadHong KongChina

Physical properties such as the conductivity are usually classified according to the symmetry of the underlying system using Neumann’s principle, which gives an upper bound for the number of independent components of the corresponding property tensor. However, for a given Hamiltonian, this global approach usually can not give a definite answer on whether a physical effect such as spin Hall effect (SHE) exists or not. It is found that the parity and types of spin-orbit interactions (SOIs) are good indicators that can further reduce the number of independent components of the spin Hall conductivity for a specific system. In terms of the parity as well as various Rashba-like and Dresselhaus-like SOIs, we propose a local approach to classify SHE in two-dimensional (2D) two-band models, where sufficient conditions for identifying the existence or absence of SHE in all 2D magnetic point groups are presented.

关键词： spin Hall effect symmetry two-dimensional system