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Dynamics of Entanglement in the Cavity with Nonlinear Medium

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Journal of Modern Physics 2013年第5期4卷 604-607页

作者： shaojiang du Hairan Feng Physics and Information Engineering Department Jining University Qufu China

We investigate the evolution of initial entangled two-atom in cavity with single-mode light field. Using the method of negative eigenvalue of partially transposed matrix we analysis the evolution of the entanglement of the two-atom in a field of number state and Kerr-media environment and find that entanglement sudden death phenomenon occurs in the number of particles field. When the atoms interact with the Kerr medium, we obtain that the phenomenon of sudden death can be eliminated in the particle-number field, and the entanglement of two-atom oscillates around a high-value.

关键词： Quantum Optics Kerr Medium Negativity Entanglement Sudden Death

Loss of GATA6-mediated up-regulation of UTX promotes pancreatic tumorigenesis and progression

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Genes & Diseases 2024年第2期11卷 921-934页

作者： Hui-Qing Zhang Fanyang Kong Xiangyu Kong Tingting Jiang Muyuan Ma shaojiang Zheng Junli Guo Keping Xie The Third Department of Medical Oncology Jiangxi Cancer HospitalNanchangJiangxi 330006China Departments of Gastroenterology Changhai HospitalSecond Military Medical UniversityShanghai 200433China Center for Pancreatic Cancer Research The South China University of Technology School of MedicineGuangzhouGuangdong 510006China Hainan Clinical Medical Research Center of the First Affiliated Hospital Hainan Women and Children's Medical CenterHainan Medical UniversityHaikouHainan 570102China Key Laboratory of Tropical Cardiovascular Diseases Research of Hainan Province Key Laboratory of Emergency and Trauma of Ministry of EducationHainan Medical UniversityHaikouHainan 571199China

Ubiquitously transcribed tetratricopeptide repeat on chromosome X(UTX),also known as lysine(K)-specific demethylase 6A(KDM6A),functions as a tumor suppressor gene or oncogene depending on the tumor type and ***,its tumor-suppressive mechanisms remain largely ***,we investigated the clinical significance and biological effects of UTX expression in pancreatic ductal adenocarcinoma(PDA)and determined the potential mechanisms of its *** expression and its association with clinicopathologic characteristics of PDA patients were analyzed using *** mRNA and protein expression and their regulation in PDA cell lines were measured using quantitative polymerase chain reaction and Western blot *** biological functions of UTX in PDA cell growth,migration,and invasion were determined using gain-and loss-of-function assays with both in vitro and in vivo animal *** expression was reduced in human PDA cell lines and *** UTX expression was associated with poor differentiation and prognosis in *** UTX expression inhibited PDA proliferation,migration,and invasion in vitro and PDA growth and metastasis in vivo,whereas knockdown of UTX expression did the ***,UTX expression was trans-activated by GATA6 ***6-mediated PDA progression could be blocked,at least partially,by silencing UTX *** conclusion,loss of GATA6-mediated UTX expression was evident in human PDA and restored UTX expression suppressed PDA growth and ***,UTX is a tumor suppressor in PDA and may serve as a prognostic biomarker and therapeutic target.

关键词： Growth Invasion Metastasis Pancreatic cancer UTX

Haploids can be induced in knockout mutants of OsPLA1,but not OsDMP3 or OsDMP6,in rice

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The Crop Journal 2024年第1期12卷 213-221页

作者： Zongkai Liu Yu Zhong Xiaolong Qi Tai An Shuwei Guo Dong Wang Yuwen Wang Bin Feng Zuofeng Zhu shaojiang Chen Chenxu Liu National Maize Improvement Center Engineering Research Center of Ministry of EducationChina Agricultural UniversityBeijing 100193China National Center for Evaluation of Agricultural Wild Plants(Rice) Department of Plant Genetics and BreedingChina Agricultural UniversityBeijing 100193China

Doubled haploid(DH)technology is an important tool in crop breeding because it can significantly accelerate the breeding ***1/MATL/NLD and ZmDMP are two key genes controlling haploid induction(HI)in maize,exhibiting a synergistic ***,it is unknown whether knock out of ZmDMP orthologs can stimulate HI in *** this study,a ZmPLA1 ortholog(OsPLA1)and two ZmDMP orthologs(OsDMP3 and OsDMP6)were identified in *** three genes encode plasma membrane-localized proteins and were highly expressed in mature *** of OsPLA1 in both Minghui 63 and Nipponbare resulted in reduced seed setting rate(SSR)and caused *** osdmp3,osdmp6 and the double mutant failed to trigger HI independently,nor increased the haploid induction rate(HIR)when combined with *** pollinations operations of QX654A with the ospla1 mutant significantly improve SSR,while reducing ***-seq profiling of mature ospla1 mutant anthers indicated that a large number of differentially expressed genes(DEGs)were enriched in redox homeostasis and lipid metabolic GO terms,plant hormone signal transduction,and MAPK signaling *** findings provide important insights towards construction of an efficient DH breeding technology and study of the molecular mechanism of HI in rice.

关键词： Doubled haploid breeding Haploid induction Mutation anlaysis Rice

Network pharmacology to decipher the mechanism of Danggui Longhui Wan against chronic myeloid leukemia

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Asian Journal of Traditional Medicines 2024年第4期19卷 177-191页

作者： Xuehan Ma Qiulin Yan shaojiang Song Guodong Yao Key Laboratory of Computational Chemistry Based Natural Antitumor Drug Research&Development Liaoning ProvinceSchool of Traditional Chinese Materia MedicaShenyang Pharmaceutical UniversityShenyang 110016China

Chronic myeloid leukemia(CML)is a hematopoietic myeloproliferative *** Chinese prescription Danggui Longhui Wan(DGLHW)has been utilized in CML treatment,but its underlying mechanisms remain *** this study,we gathered 794 constituents,1249 drug targets,1654 disease genes and 129 intersection *** and KEGG were used to analyze the function of these *** of prescription study showed that monarch drug,minister drug,assistant and guide drug played a synergistic role in the treatment of *** addition,we obtained 20 hub genes and 12 key *** docking indicated that the main compounds and core proteins had good binding *** results of this study also showed that DGLHW might play a role in the treatment of CML by affecting MAPK,PI3K/AKT,FoxO and p53 signaling pathways.

关键词： chronic myeloid leukemia Danggui Longhui Wan network pharmacology compatibility analysis

基于改进多尺度卷积循环神经网络的滚动轴承故障研究

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振动与冲击 2024年第20期43卷 94-105页

作者：董绍江黄翔夏宗佑邹松重庆交通大学机电与车辆工程学院重庆400074

针对传统卷积神经网络故障诊断方法提取特征不丰富,容易丢失故障敏感信息,且在单一尺度处理方法限制实际复杂工况下故障特性的深度挖掘问题,提出了注意力机制的多尺度卷积神经网络和双向长短期记忆(bi-directional long short-term memo... 详细信息

针对传统卷积神经网络故障诊断方法提取特征不丰富,容易丢失故障敏感信息,且在单一尺度处理方法限制实际复杂工况下故障特性的深度挖掘问题,提出了注意力机制的多尺度卷积神经网络和双向长短期记忆(bi-directional long short-term memory,BiLSTM)网络融合的迁移学习故障诊断方法。该方法首先应用不同尺寸池化层和卷积核捕获振动信号的多尺度特征;然后引入多头自注意力机制自动地给予特征序列中的不同部分不同的权重,进一步加强特征表示的能力;其次利用BiLSTM结构引入双向性质提取特征前后之间的内部关系实现信息的逐层传递;最后利用多核最大均值差异减小源域和目标域在预训练模型中各层上的概率分布差异并利用少量标记的目标域数据再对模型进行训练。试验结果表明,所提方法在江南大学(JNU)、德国帕德博恩大学(PU)公开轴承数据集上平均准确率分别为98.43%和97.66%,该方法在重庆长江轴承股份有限公司自制的轴承故障数据集上也表现出了极高的准确率和较快的收敛速度,为有效诊断振动旋转部件故障提供了实际依据。

关键词：故障诊断多尺度卷积神经网络双向长短期记忆(BiLSTM)网络多头自注意力多核最大均值差异

基于改进相变方程的形状记忆合金弹性耦合系统特性分析

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机械工程学报 2024年第14期60卷 194-205页

作者：朱孙科闵旭董绍江重庆交通大学机电与车辆工程学院重庆400074

为准确描述形状记忆合金(Shape memory alloy,SMA)弹性耦合系统的驱动特性,考虑模型复杂程度与工程实际需求,提出了一种基于Brinson本构方程和SMA相变原理的改进相变模型。针对Brinson相变模型SMA马氏体正相变过程中马氏体分数不连续的... 详细信息

为准确描述形状记忆合金(Shape memory alloy,SMA)弹性耦合系统的驱动特性,考虑模型复杂程度与工程实际需求,提出了一种基于Brinson本构方程和SMA相变原理的改进相变模型。针对Brinson相变模型SMA马氏体正相变过程中马氏体分数不连续的问题,将孪晶马氏体相转化为孪晶马氏体相和非孪晶马氏体相相混合相终点时各晶体体积分数,作为马氏体正相变终点时的晶体体积分数,视马氏体正相变为一个连续的过程,对原Brinson相变模型中马氏体正相变方程进行修正。以偏置式SMA丝驱动器为研究对象,建立了SMA弹性耦合系统模型,采用改进的Brinson相变模型分别对具有不同偏置弹簧的系统进行仿真分析,并与相应试验结果比较。结果表明,改进相变模型的计算结果与试验吻合较好,且在相变过程中马氏体相和奥氏体相体积分数和为1,符合实际情况。分析发现,对于SMA弹性耦合系统,偏置弹簧的刚度越大,驱动器响应速度越慢,相变温度区间和完全马氏体逆相变所需的加热电流越大,驱动应变先增加后减小。研究结果可更准确地描述SMA驱动器的作动过程,为偏置式SMA丝驱动器的设计提供参考。

关键词：形状记忆合金驱动特性相变方程偏置弹簧

改进YOLOv5s的弱光水下生物目标检测算法

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北京航空航天大学学报 2024年第2期50卷 499-507页

作者：陈宇梁董绍江孙世政闫凯波重庆交通大学机电与车辆工程学院重庆400074

针对水下光学图像目标检测过程中由于水中光线衰弱严重、图像环境复杂和拍摄设备移动等造成的生物识别精度低的问题,提出了基于改进YOLOv5s的弱光水下生物目标实时检测算法YOLOv5s-underwater。针对弱光水下光线衰弱的问题,引入了限制... 详细信息

针对水下光学图像目标检测过程中由于水中光线衰弱严重、图像环境复杂和拍摄设备移动等造成的生物识别精度低的问题,提出了基于改进YOLOv5s的弱光水下生物目标实时检测算法YOLOv5s-underwater。针对弱光水下光线衰弱的问题,引入了限制对比度自适应直方图均衡(CLAHE)算法对输入图像进行预处理,解决了颜色失真和图像毛糙的问题。针对复杂的弱光水下图像环境,提出了快速空间金字塔池化(SPPF)模块,解决了水下物体区分度低和特征损失严重的问题。针对拍摄设备移动带来的场景和形态变化问题,提出了一种基于旋转窗口的Swin-Transformer模块,提高了模型的泛化能力。针对水下小目标,修改了网络模型结构,提高了小目标的检测能力。仿真和实验结果表明:所提算法相较于YOLOv5s检测精度提高30.7%,证明了算法的有效性。

关键词：弱光水下生物目标 YOLOv5s 限制对比度自适应直方图均衡快速空间金字塔池化旋转窗口

基于TCN和残差自注意力的变工况下滚动轴承剩余寿命迁移预测

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振动与冲击 2024年第1期43卷 145-152页

作者：潘雪娇董绍江朱朋周存芳宋锴重庆交通大学交通运输学院重庆400074 重庆交通大学机电与车辆工程学院重庆400074 重庆大学机械与运载工程学院重庆400044 重庆长安汽车股份有限公司重庆401120

针对变工况环境下采集到的滚动轴承寿命状态数据存在特征分布差异,深度神经网络模型泛化能力差的问题,结合时间卷积网络(temporal convolutional neural network,TCN)和残差自注意力机制提出了一种端到端的滚动轴承剩余寿命(remaining u... 详细信息

针对变工况环境下采集到的滚动轴承寿命状态数据存在特征分布差异,深度神经网络模型泛化能力差的问题,结合时间卷积网络(temporal convolutional neural network,TCN)和残差自注意力机制提出了一种端到端的滚动轴承剩余寿命(remaining useful life,RUL)迁移预测方法。首先,将传感器采集到的一维时域信号利用短时傅里叶变换转换为频域信号;其次,剩余寿命迁移预测网络通用特征提取层采用残差自注意力TCN网络,该网络在较好提取时间序列信息的同时,进一步通过残差自注意力机制捕获轴承局部退化特征,增强模型的迁移特征提取能力;再次,采用提出的联合领域自适应策略匹配变工况下滚动轴承寿命状态数据特征分布差异,实现不同工况下轴承寿命状态知识的迁移预测;最后,在公开的滚动轴承全寿命数据集上进行试验验证,结果表明所提方法能有效实现变工况下的滚动轴承RUL预测,并获得较好的预测性能。

关键词：剩余寿命(RUL) 滚动轴承时间卷积网络(TCN) 残差自注意力迁移学习

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改进YOLOv5s的桥梁表观病害检测方法

重庆大学学报 2024年第9期47卷 91-100页

作者：董绍江谭浩刘超胡小林重庆交通大学机电与车辆工程学院重庆400074 重庆工业大数据创新中心有限公司重庆404100

针对已有目标检测方法在混凝土桥梁表观病害检测的应用中识别精度低且伴随较多误检和漏检的问题,提出了一种改进的YOLOv5s桥梁表观病害检测方法。针对目前桥梁表观病害特征成分较复杂的问题,为了更有效地利用不同尺度的缺陷特征,在主干... 详细信息

针对已有目标检测方法在混凝土桥梁表观病害检测的应用中识别精度低且伴随较多误检和漏检的问题,提出了一种改进的YOLOv5s桥梁表观病害检测方法。针对目前桥梁表观病害特征成分较复杂的问题,为了更有效地利用不同尺度的缺陷特征,在主干网中添加修改后的空间金字塔池化模块,提高了整体网络对缺陷特征信息的获取能力,同时减少了运算工作量;针对由病害图像中不同缺陷特征交叉分布导致的误检率、漏检率高的问题,在YOLOv5s网络中加入轻量化注意力模块;针对桥梁缺陷尺寸差异大、分类困难和数据集小而导致的边界回归不匹配的问题,采用考虑了向量角度的损失函数。实验证明,改进后的YOLOv5s检测器在桥梁表观病害目标检测识别任务中能够有效提高精度、降低误检率和漏检率。

关键词：病害检测 YOLOv5s 特征融合平均精度

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