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Continuous variable quantum teleportation and remote state preparation between two space-separated local networks

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Science China(Information Sciences) 2024年第4期67卷 314-322页

作者： Siyu REN Dongmei HAN meihong WANG Xiaolong SU State Key Laboratory of Quantum Optics and Quantum Optics Devices Institute of Opto-ElectronicsShanxi University Collaborative Innovation Center of Extreme Optics Shanxi University

Implementing quantum communication between space-separated local networks is essential for designing global quantum networks. In this study, we propose quantum teleportation and remote state preparation schemes between users of two space-separated local networks established by continuous-variable multipartite entangled states. In the proposed schemes, the quantum nodes belonging to the two distant local networks are first entangled by entanglement swapping, and then quantum communication protocols are realized. We show that quantum teleportation between any two users belonging to space-separated local networks can be realized with the assistance of other users, and squeezed thermal states can be remotely prepared in one local network by performing a homodyne projective measurement on the state in another distant local network. Our results provide a feasible approach for quantum communication between spaceseparated quantum networks with multipartite entangled states.

关键词： quantum communication quantum network quantum teleportation remote state preparation entanglement swapping continuous variable

lncRNA MALAT1调控miR-204表达影响胰腺癌细胞的生物学行为

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中国肿瘤生物治疗杂志 2018年第1期25卷 79-84页

作者：张小路杜梅红河南中医药大学第二附属医院河南省中医院普外二科河南郑州450002 河南中医药大学第二附属医院河南省中医院放射科河南郑州450002

目的:探讨长链非编码RNA(long chain non-coding RNA,lnc RNA)肺腺癌转移相关转录因子1(metastasis-associated lung adenocarcinoma transcript 1,MALAT1)通过调控miR-204的表达影响胰腺癌细胞恶性生物学行为的作用及其可能机制。方法:收集2016年10月至2016年12月在河南省中医院6例胰腺癌手术切除标本及其对应的癌旁组织标本。用实时荧光定量PCR检测胰腺癌组织和癌旁组织、5种胰腺癌细胞(Bx PC-3、HS-7667、PANC-1、As PC-1和SW-1990)中lnc RNA MALAT1的表达,双荧光素酶报告基因检测MALAT1与miR-204的相互作用,流式细胞术分析MALAT-1对胰腺癌细胞的细胞周期及细胞凋亡的影响;划痕愈合实验和Transwell侵袭实验检测MALAT1和miR-204对胰腺癌细胞迁移和侵袭能力的影响,Western blotting检测MALAT1对上皮间质转化相关蛋白的影响。结果:lnc RNA MALAT1在胰腺癌组织中表达水平明显高于癌旁组织(1.85±0.52vs 0.34±0.12,P<0.05),MALAT1在SW-1990细胞中的表达水平最高(P<0.05)。lnc RNA MALAT1能与miR-204的3’UTR特异性结合,调控miR-204的表达活性。抑制MALAT1表达后,可诱导SW-1990细胞G2/M细胞周期停滞、促进细胞凋亡,SW-1990细胞的迁移和侵袭能力减弱(均P<0.05),下调SW-1990细胞N-cadherin、E-cadherin和vimentin的表达。过表达miR-204可促进SW-1990细胞迁移和侵袭。结论:lnc RNA MALAT1通过靶向调控miR-204表达影响胰腺癌细胞的恶性生物学行为,在胰腺癌的发生发展过程中起重要作用。

关键词：胰腺癌 SW-1990细胞 lncRNA MALAT1 微小RNA-214(miR-204) 迁移侵袭

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基于损失平滑的对抗样本攻击方法

北京航空航天大学学报 2024年第2期50卷 663-670页

作者：黎妹红金双杜晔北京交通大学智能交通数据安全与隐私保护技术北京市重点实验室北京100044 北京交通大学计算机与信息技术学院北京100044

深度神经网络(DNNs)容易受到对抗样本的攻击,现有基于动量的对抗样本生成方法虽然可以达到接近100%的白盒攻击成功率,但是在攻击其他模型时效果仍不理想,黑盒攻击成功率较低。针对此,提出一种基于损失平滑的对抗样本攻击方法来提高对抗... 详细信息

深度神经网络(DNNs)容易受到对抗样本的攻击,现有基于动量的对抗样本生成方法虽然可以达到接近100%的白盒攻击成功率,但是在攻击其他模型时效果仍不理想,黑盒攻击成功率较低。针对此,提出一种基于损失平滑的对抗样本攻击方法来提高对抗样本的可迁移性。在每一步计算梯度的迭代过程中,不直接使用当前梯度,而是使用局部平均梯度来累积动量,以此来抑制损失函数曲面存在的局部振荡现象,从而稳定更新方向,逃离局部极值点。在ImageNet数据集上的大量实验结果表明:所提方法与现有基于动量的方法相比,在单个模型攻击实验中的平均黑盒攻击成功率分别提升了38.07%和27.77%,在集成模型攻击实验中的平均黑盒攻击成功率分别提升了32.50%和28.63%。

关键词：深度神经网络对抗样本黑盒攻击损失平滑人工智能安全

Advances of high-performance LiNi_(1-x-y)Co_(x)M_(y)O_(2) cathode materials and their precursor particles via co-precipitation process

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Particuology 2024年第3期86卷 67-85页

作者： Wenbiao Liang Yin Zhao Liyi Shi Zhuyi Wang Yi Wang meihong Zhang Shuai Yuan School of Materials Science and Engineering Shanghai UniversityShanghai200444China Research Center of Nanoscience and Nanotechnology Shanghai UniversityShanghai200444China Emerging Industries Institute Shanghai UniversityJiaxingZhejiang314006China

Layered LiNi_(1-x-y)Co_(x)M_(y)O_(2)(M=Mn or Al)is a promising cathode material for lithium-ion batteries due to its high specific capacity and acceptable manufacturing ***,the polycrystalline LiNi_(1-x-y)Co_(x)M_(y)O_(2) cathode material suffers from disordered orientation of primary particles and poor geometric symmetry of secondary particles,which severely hampers the migration of Lit ***,the resulting anisotropy accelerates the disintegration of the secondary particle structure,significantly affecting the electrochemical performance of the polycrystalline *** spite of less grain boundary,the single-crystal LiNi_(1-x-y)Co_(x)M_(y)O_(2) cathodes still suffer from severe microcracks generated by repeated planar gliding during cycling,which poses a great challenge to the cycling stability of single-crystal ***'s worth noting that the microstructure of the cathode material is mainly inherited from its ***,it is necessary to deeply understand the influence of the microstructure of Ni_(1-x-y)Co_(x)M_(y)(OH)2 on the electrochemical properties of LiNi_(1-x-y)Co_(x)M_(y)O_(2) cathode materials,so as to optimize the production process of preparing high-performance cathode *** this review,we summarize recent advances in the research and development of Ni-rich cathode precursor ***,the challenges faced by the Ni-rich hydroxide precursor materials are presented,including the effect of primary particle morphology and arrangement on the electrochemical performance of cathode materials,the influence of secondary particle morphology on lithium insertion reactions in cathode,and the effect of particle size on the microcracking of single-crystal ***,the presentation of the conventional co-precipitation reactor,the mechanism of precursor particle growth,and the influence of coprecipitation parameters are described in ***,the strategies are systematically discussed to solve the cha

关键词： Lithium-ion batteries Cathode materials Co-precipitation Ni-rich layered oxides Single crystal Precursor particles

Cyanidin-3-O-glucoside alleviates trimethyltin chloride-induced neurodegeneration by maintaining glutamate homeostasis through modulation of the gut microbiota

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Food Science and Human Wellness 2024年第2期13卷 1093-1107页

作者： Yu Xi Wenhui Li Junru Wang meihong Yu Xiangquan Zeng He Li Jian Li Key Laboratory of Green and Low-Carbon Processing Technology for Plant-Based Food of China National Light Industry Council Beijing Advanced Innovation Center for Food Nutrition and Human HealthBeijing Technology and Business UniversityBeijing 100048China

Trimethyltin chloride(TMT)is a potent neurotoxin to cause neurodegeneration,especially in *** study aimed to identify dietary components that can effectively attenuate TMT-induced neurodegeneration in *** predominant anthocyanin in human diets,cyanidin-3-O-glucoside(C3G,5 or 50 mg/kg),was given to mice for 16 days,and TMT(2.7 mg/kg)was injected intraperitoneally once on the eighth day.C3G(50 mg/kg)significantly alleviated TMT-induced seizures and subsequent cognitive impairment by ameliorating hippocampal neurodegeneration and synaptic ***,C3G treatment restored glutamate homeostasis in brain and reversed glutamine synthetase(GS)inhibition in reactive astrogliosis and neuroinflammation,which are critical for C3G's neuroprotective ***,C3G decreased the lipopolysaccharide,tumor necrosis factor-α,interleukin-6,and interleukin-1βlevels in the mice,which potentially by modulating the relative abundance of Atopobiaceae and Lachnospiraceae in the gut.C3G may be a promising and practical dietary component for reducing TMT-induced neurodegeneration.

关键词： Cyanidin-3-O-glucoside Trimethyltin Neurodegeneration Glutamatergic pathway Gut microbiota

Preparation of Immunomagnetic Beads Enrichment Kit for Detection of Aflatoxin B1

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Plant Diseases and Pests 2018年第3期9卷 1-3页

作者： Wu Xiaosheng Wang Zhaoqin Jia Fangfang du meihong Cui Tingting Cui Haifeng Cao Dongshan Wan Yuping Beijing Kwinbon Biotechnology Co. Ltd. Beijing 102206 China Beijing Rapid Detection Engineering Technical Center for Food Safety and Immunization Beijing 102206 China Beijing Physical and Chemical Analysis Testing Center Beijing 100089 China

Immunomagnetic beads enrichment kit for detection of aflatoxin B1(AFB1) was prepared through reaction of AFB1 and p-phenylenediamine. The catches of AFB1 by the kit were 25 ng/mg. Furthermore, AFB1 was conducted specific reaction with competitive drugs with similar structure or function to AFB1, including aflatoxin M1, T-2 toxin, ochratoxin A, zearalenone and patulin, and no cross reaction was observed.

关键词： Aflatoxin B1(AFB1) Monoclonal antibody Immunomagnetic beads enrichment kit

Distribution of polarization squeezed light through a 20 km fiber channel

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Science China(Information Sciences) 2024年第5期67卷 343-344页

作者： Chao LI Siyu REN Yanru YAN Yalin LI meihong WANG Xiaolong SU State Key Laboratory of Quantum Optics and Quantum Optics Devices Institute of Opto-Electronics Shanxi University Collaborative Innovation Center of Extreme Optics Shanxi University

Polarization squeezed light plays a key role in quantum memory by transferring quantum information between atoms and photons [1], and has potential applications in quantum precision measurement [2]. For polarization squeezed light, the quantum variance of at least one Stokes operator is smaller than that of the coherent *** with the quadrature squeezed state, polarization squeezed light has the following advantages: one is that it is a bright beam, and the other is that it can be measured directly without using a local oscillator.

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Preparation of a Salmonella LAMP Detection Kit

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Agricultural Biotechnology 2019年第6期8卷 97-99,103页

作者： Yuping WAN Xiaosheng WU Yu ZHANG meihong du Zhaoqin WANG Caiwei FENG Zhengmiao ZHAO Fangyang HE Beijing Kwinbon Biotechnology Co. Ltd.Beijing 102206China Beijing Engineering Technology Research Center of Food Safety Immune Rapid Detection Beijing 102206China Beijing center for physical&chemical analysis Beijing 100089China

[Objectives] This study was conducted to establish a method for rapid detection of Salmonella at the grassroots level, and a corresponding product was developed. [Methods] By analyzing the invA gene of Salmonella, two pairs of efficient, rapid and specific amplification primers were designed and screened for the six conserved domains of the gene, and the LAMP detection kit for Salmonella based on this method was produced. [Results] The method is simple, sensitive, rapid and specific. The minimum detection concentration is 10~2-10~3 CFU/ml. [Conclusions] It can be used in the self-inspection of food production enterprises and the on-site sampling inspection and rapid detection of large quantities of samples by grassroots food safety inspection and supervision departments.

关键词： LAMP Salmonella Rapid detection

Ginkgo biloba extract alleviates fatty liver hemorrhagic syndrome in laying hens via reshaping gut microbiota

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Journal of Animal Science and Biotechnology 2024年第1期15卷 277-294页

作者： Xinyue Yang Depeng Li meihong Zhang Yuqing Feng Xiaolu Jin Dan Liu Yuming Guo Yongfei Hu State Key Laboratory of Animal Nutrition College of Animal Science and TechnologyChina Agricultural UniversityBeijing 100193China

Background Ginkgo biloba extract(GBE)is evidenced to be effective in the prevention and alleviation of metabolic disorders,including obesity,diabetes and fatty liver ***,the role of GBE in alleviating fatty liver hemorrhagic syndrome(FLHS)in laying hens and the underlying mechanisms remain to be ***,we investigated the effects of GBE on relieving FLHS with an emphasis on the modulatory role of GBE in chicken gut *** The results showed that GBE treatment ameliorated biochemical blood indicators in high-fat diet(HFD)-induced FLHS laying hen model by decreasing the levels of TG,TC,ALT and *** lipid accumulation and pathological score of liver were also relieved after GBE ***,GBE treatment enhanced the antioxidant activity of liver and serum by increasing GSH,SOD,T-AOC,GSH-PX and reducing MDA,and downregulated the expression of genes related to lipid synthesis(FAS,LXRα,GPAT1,PPARγand Ch REBP1)and inflammatory cytokines(TNF-α,IL-6,TLR4 and NF-κB)in the *** profiling analysis revealed that GBE treatment reshaped the HFD-perturbed gut microbiota,particularly elevated the abundance of Megasphaera in the ***,targeted metabolomic analysis of SCFAs revealed that GBE treatment significantly promoted the production of total SCFAs,acetate and propionate,which were positively correlated with the GBE-enriched gut ***,we confirmed that the GBE-altered gut microbiota was sufficient to alleviate FLHS by fecal microbiota transplantation(FMT).Conclusions We provided evidence that GBE alleviated FLHS in HFD-induced laying hens through reshaping the composition of gut *** findings shed light on mechanism underlying the anti-FLHS efficacy of GBE and lay foundations for future use of GBE as additive to prevent and control FLHS in laying hen industry.

关键词： Antioxidation Fecal microbiota transplantation FLHS Ginkgo biloba extract Inflammation Megasphaera