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Low-intensity pulsed ultrasound reduces alveolar bone resorption during orthodontic treatment via Lamin A/C-Yes-associated protein axis in stem cells

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World Journal of Stem Cells 2024年第3期16卷 267-286页

作者： Tong Wu Fu zheng Hong-Yi Tang Hua-Zhi Li Xin-Yu Cui Shuai ding duo Liu Cui-Ying Li Jiu-Hui Jiang Rui-Li Yang Department of Orthodontics Peking University School and Hospital of StomatologyNational Engineering Laboratory for Digital and Material Technology of StomatologyBeijing Key Laboratory of Digital StomatologyBeijing 100081China Department of Central Laboratory Peking University School and Hospital of StomatologyNational Clinical Research Center for Oral Diseases&National Engineering Laboratory for Digital and Material Technology of StomatologyBeijing Key Laboratory of Digital StomatologyBeijing 100081China

BACKGROUND The bone remodeling during orthodontic treatment for malocclusion often requires a long duration of around two to three years,which also may lead to some complications such as alveolar bone resorption or tooth root ***-intensity pulsed ultrasound(LIPUS),a noninvasive physical therapy,has been shown to promote bone fracture *** is also reported that LIPUS could reduce the duration of orthodontic treatment;however,how LIPUS regulates the bone metabolism during the orthodontic treatment process is still *** To investigate the effects of LIPUS on bone remodeling in an orthodontic tooth movement(OTM)model and explore the underlying *** A rat model of OTM was established,and alveolar bone remodeling and tooth movement rate were evaluated via micro-computed tomography and staining of tissue *** vitro,human bone marrow mesenchymal stem cells(hBMSCs)were isolated to detect their osteogenic differentiation potential under compression and LIPUS stimulation by quantitative reverse transcription-polymerase chain reaction,Western blot,alkaline phosphatase(ALP)staining,and Alizarin red *** expression of Yes-associated protein(YAP1),the actin cytoskeleton,and the Lamin A/C nucleoskeleton were detected with or without YAP1 small interfering RNA(siRNA)application via *** The force treatment inhibited the osteogenic differentiation potential of hBMSCs;moreover,the expression of osteogenesis markers,such as type 1 collagen(COL1),runt-related transcription factor 2,ALP,and osteocalcin(OCN),*** could rescue the osteogenic differentiation of hBMSCs with increased expression of osteogenic marker inhibited by ***,the expression of LaminA/C,F-actin,and YAP1 was downregulated after force treatment,which could be rescued by ***,the osteogenic differentiation of hBMSCs increased by LIPUS could be attenuated by YAP siRNA ***,LIPUS increased alveolar

关键词： Low-intensity pulsed ultrasound Bone resorption Osteogenesis Cytoskeleton-Lamin A/C-Yes-associated protein axis Bone marrow mesenchymal stem cells Orthodontic tooth movement

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非晶丝材料磁阻抗特性测量系统研制

实验技术与管理 2011年第11期 280-285页

作者：王立锦周毛毛龚占双丁毅寿李希胜于广华北京科技大学材料科学与工程学院北京科技大学信息工程学院

将幅频/相频分析专用集成电路芯片AD8302用于非晶丝磁阻抗特性的测量中,结合磁场自动扫描技术、计算机自动数据采集技术设计制作了磁阻抗特性测试系统,实现了非晶丝磁阻抗特性的自动化测量。该系统集样品信号驱动调理、数据采样、数据... 详细信息

将幅频/相频分析专用集成电路芯片AD8302用于非晶丝磁阻抗特性的测量中,结合磁场自动扫描技术、计算机自动数据采集技术设计制作了磁阻抗特性测试系统,实现了非晶丝磁阻抗特性的自动化测量。该系统集样品信号驱动调理、数据采样、数据处理、参数计算等功能于一体,测试范围宽、精度高、用户界面友好。数据采集控制软件还能在计算机屏幕、打印机上绘出被测样品的磁阻抗特性曲线,并生成标准数据文件供ORIGIN等数据处理软件调用。对实际非晶丝样品进行了测试分析,效果良好。

关键词：非晶丝磁阻抗 VB语言计算机辅助测试幅/相分析技术

Numerical Investigation on Heat Transfer Characteristics of Microencapsulated Phase Change Material Slurry in a Rectangular Minichannel

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Journal of Thermal science 2024年第2期33卷 564-577页

作者： WANG Zhibin LI Zilong JIA Lisi ding Bin CHEN Ying school of materials and Energy Guangdong University of TechnologyGuangzhou510006China Guangdong Provincial Key Laboratory of Functional Soft Condensed Matter Guangzhou510006China College of New Energy China University of Petroleum(East China)Qingdao266580China

Microencapsulation phase change material slurry(MEPCMS) becomes a potential working fluid for cooling high energy density miniaturized components,thanks to the latent heat absorption of particles in the heat transfer *** this work,the Discrete Phase Model(DPM) based on the Euler-Lagrangian method is used to numerically investigate the convective heat transfer characteristics of MEPCMS flowing through a rectangular minichannel with constant heat *** results show that particles of MEPCMS are mainly subjected to drag force during the *** so,they can migrate from the high-temperature region to the low-temperature region driven by the thermophoretic force,affecting the particle distribution and phase change ***,the Nux of the MEPCMS fluctuates due to particle phase change with varying specific heat ***,the value increases first,then decreases,and eventually increases again until it approaches the fully developed value of the pure base fluid as the particles gradually ***,the heat transfer performance of the MEPCMS is influenced by the combination of fluid inlet temperature fluid inlet velocity(v),and mass concentration(c_(m)) of MEPCM *** result shows that the maximum reduction of the maximum bottom wall temperature difference(ΔT_(w)) is 23.98% at T_(in)=293.15 K,v=0.15 m·s^(-1),c_(m)=10%.

关键词： Microencapsulated Phase Change Material Slurry(MPCMS) Discrete Phase Model(DPM) particle-fluid interaction force minichannel heat sink thermophoresis

Steric hindrance modulation of hexaazatribenzanthraquinone isomers for high-capacity and wide-temperature-range aqueous proton battery

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National science Review 2024年第4期11卷 271-282页

作者： Mingsheng Yang Yuxin hao Bei Wang Yan Wang Liping zheng Rui Li Huige Ma Xinyu Wang Xiaoming Jing Hongwei Li Mengxiao Li Zhihui Wang Yujie Dai Guangcun Shan Mingjun Hu Jun Luo Jun Yang school of materials science and Engineering Beihang University beijing Institute of Nanoenergy &Nanosystems Chinese Academy of Sciences Center on Nanoenergy Research School of Physical Science & TechnologyGuangxi University school of Chemistry and Chemical Engineering Center on Nanoenergy Research Guangxi University school of Instrumentation science and Opto-electronics Engineering Beihang University ShenSi Lab Shenzhen Institute for Advanced StudyUniversity of Electronic Science and Technology of China

Organic materials with rich active sites are good candidates of high-capacity anodes in aqueous batteries,but commonly low utilization of active sites limits their ***,two isomers,symmetric and asymmetric hexaazatribenzanthraquinone（s-HATBAQ and a-HATBAQ）,with rich active sites have been synthesized in a controllable *** has been revealed for the first time that a sulfuric acid catalyst can facilitate the stereoselective formation of *** to the reduced steric hindrance in favor of proton insertion as well as the amorphous structure conducive to electrochemical dynamics,s-HATBAQ exhibits 1.5 times larger specific capacity than ***,the electrode of s-HATBAQ with50% reduced graphene oxide（s-HATBAQ-50%rGO） delivers a record high specific capacity of405 mAh g-1in ***,the assembled MnO2//s-HATBAQ-50%rGO aqueous proton full batteries show an exceptional cycling stability at 25℃ and can maintain ～92% capacity after1000 cycles at 0.5 A g-1at-80℃.This work demonstrates the controllable synthesis of isomers,showcases a wide-temperature-range prototype proton battery and highlights the significance of precise mole cular structure modulation in organic energy storage.

关键词： stereoisomers steric effect aqueous battery super cycling stability ultra-low temperature proton battery

Tectonic evolution of the Qinling-Tongbai orogenic belt

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Tectonic evolution of the Qinling-Tongbai orogenic belt

An effective catalyst carrier SiO_(2):Enhancing catalytic and combustion properties of CuFe_(2)O_(4)on energetic components

中国矿物岩石地球化学学会第13届学术年会

作者： WU Yuan-bao~1,zheng Yong-fei~2 1.State Key Laboratory of Geological Processes and Mineral Resources,Faculty of Earth sciences,china university of geosciences, Wuhan 430074,china 2.CAS Key Laboratory of Crust-Mantle materials and Environments,school of Earth and Space sciences,university of science and technology of china,Hefei 230026,china

＜正＞The Qinling-Tongbai-Dabie-Sulu orogenic belt marks the suture between the North and South china Blocks in Central china,forming one of the most important orogens in the eastern *** are hot controversies about the location and number of sutures and the timing of arc-continent and continent-continent collisions during the convergence between the North and South china *** Dabie-Sulu orogenic belt is characterized by the occurrence of Triassic UHP eclogite-facies metamorphic rocks due to the Triassic continental deep subduction. Thus,the Triassic continent-continent collision is evident in east-central *** the other hand,there are Paleozoic events of arc-continent collision in the Qinling-Tongbai orogenic belt that were overprinted by the Triassic process of continental *** has caused much complexity on the time and location of arc-continent and continent-continent collisions between the North and South china *** present an

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Defence technology（防务技术） 2024年第2期32卷 383-392页

作者： Li ding Chong Wan Suhang Chen Zhao Qin Kangzhen Xu school of Chemical Engineering/Xi'an Key Laboratory of Special Energy materials Northwest UniversityXi'an710069China Xi’an Modern Chemistry Research Institute Xi'an710065China

To enhance the catalytic activity of copper ferrite(CuFe_(2)O_(4))nanoparticle and promote its application as combustion catalyst,a low-cost silicon dioxide(SiO_(2))carrier was employed to construct a novel CuFe_(2)O_(4)/SiO_(2)binary composites via solvothermal *** phase structure,morphology and catalytic activity of CuFe_(2)O_(4)/SiO_(2)composites were studied firstly,and thermal decomposition,combustion and safety performance of ammonium perchlorate(AP)and 1,3,5-trinitroperhydro-1,3,5-triazine(RDX)with it affecting were then systematically *** results show that CuFe_(2)O_(4)/SiO_(2)composite can remarkably either advance the decomposition peak temperature of AP and RDX,or reduce the apparent activation energy at their main decomposition ***,the flame propagation rate of RDX was promoted by about 2.73 times with SiO_(2)content of 3 wt%,and safety property of energetic component was also improved greatly,in which depressing the electrostatic discharge sensitivity of pure RDX by about 1.89 *** addition,the effective range of SiO_(2)carrier content in the binary catalyst is found to be 3 to 5 wt%.Therefore,SiO_(2)opens a new insight on the design of combustion catalyst carrier and will promote the application of CuFe_(2)O_(4)catalyst in solid propellant.

关键词： Copper ferrite Silicon dioxide Combustion catalyst Thermal decomposition Laser ignition

Evidence for reversible oxygen ion movement during electrical pulsing:enabler of emerging ferroelectricity in binary oxides

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materials Futures 2024年第3期3卷 195-205页

作者： Huan Liu Fei Yu Bing Chen zheng-Dong Luo Jiajia Chen Yong Zhang Ze Feng Hong Dong Xiao Yu Yan Liu Genquan Han Yue hao State Key Discipline Laboratory of Wide Band Gap Semiconductor technology School of MicroelectronicsXidian UniversityXi’an 710071People’s Republic of China Research Center for Intelligent Chips and Devices Zhejiang LabHangzhou 311121People’s Republic of China Engineering Research Center of Thin Film Optoelectronics technology Ministry of EducationNankai UniversityTianjin 300350People’s Republic of China

Ferroelectric HfO_(2)-based materials and devices show promising potential for applications in information technology but face challenges with inadequate electrostatic control,degraded reliability,and serious variation in effective oxide thickness *** demonstrate a novel interface-type switching strategy to realize ferroelectric characteristics in atomic-scale amorphous binary oxide films,which are formed in oxygen-deficient conditions by atomic layer deposition at low *** approach can avoid the shortcomings of reliability degradation and gate leakage increment in scaling polycrystalline doped HfO_(2)-based *** theoretical modeling and experimental characterization,we show the following.(1)Emerging ferroelectricity exists in ultrathin oxide systems as a result of microscopic ion migration during the switching process.(2)These ferroelectric binary oxide films are governed by an interface-limited switching mechanism,which can be attributed to oxygen vacancy migration and surface defects related to electron(de)trapping.(3)Transistors featuring ultrathin amorphous dielectrics,used for non-volatile memory applications with an operating voltage reduced to±1 V,have also been experimentally *** findings suggest that this strategy is a promising approach to realizing next-generation complementary metal-oxide semiconductors with scalable ferroelectric materials.

关键词： ferroelectric binary oxide mobile ion amorphous dielectric nonvolatile memory

Case Report:Lance-Adams syndrome:a report of two cases

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Journal of Zhejiang university-science B(Biomedicine & Biotechnology) 2007年第10期8卷 715-720页

作者： ZHANG Yan-xing1,2, LIU Jian-ren1, JIANG biao3, LIU Hui-qin1, ding Mei-ping1, SONG Shui-jiang1, ZHANG Bao-rong1, ZHANG Hong4, XU Bin5, CHEN Huai-hong6, WANG Zhong-jin1, HUANG Jian-zheng1 (1Department of Neurology, the Second Affiliated Hospital, school of Medicine, Zhejiang university, Hangzhou 310009, china) (2Department of Neurology, Shaoxing People’s Hospital, Shaoxing 312000, china) (3Department of Radiology, the Second Affiliated Hospital, school of Medicine, Zhejiang university, Hangzhou 310009, china) (4Department of Nuclear Medicine, the Second Affiliated Hospital, school of Medicine, Zhejiang university, Hangzhou 310009, china) (5Department of Neurology, the Second Affiliated Hospital, Zhejiang university of Traditional Chinese Medicine, Hangzhou 310005, china) (6Department of Geratology, the Second Affiliated Hospital, school of Medicine, Zhejiang university, Hangzhou 310009, china) Department of Neurology the Second Affiliated Hospital School of Medicine Zhejiang University Department of Neurology Shaoxing People’s Hospital Department of Radiology the Second Affiliated Hospital School of Medicine Zhejiang University

Chronic post-hypoxic myoclonus, also known as Lance-Adams syndrome (LAS), is a rare complication of successful cardiopulmanry resuscitation often accompanied by action myoclonus and cerebellar ataxia. It is seen in patients who have un-dergone a cardiorespiratory arrest, regained consciousness afterwards, and then developed myoclonus days or weeks after the event. Worldwide, 122 cases have been reported in the literature so far, including 1 case of Chinese. Here we report 2 Chinese LAS patients with detailed neuroimagings. Cranial single photon emission computed tomography (SPECT) of patient 1, a 52-year-old woman, showed a mild hypoperfusion in her left temporal lobe, whereas patient 2, a 54-year-old woman, manifested a mild bilateral decrease of glucose metabolism in the frontal lobes and a mild to moderate decrease of the N-acetyl aspartate (NAA) peak in the bilateral hippocampi by cranial [18F]-fluorodeoxyglucose positron emission tomographic (PET) scan and cranial magnetic resonance spectroscopy (MRS), respectively. We also review the literature on the neuroimaging, pathogenesis, and treatment of LAS.

关键词： Lance-Adams syndrome Chronic post-hypoxic myoclonus Action myoclonus Cerebellar ataxia Single photon emission computed tomography Positron emission tomography Magnetic resonance spectroscopy

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新的非比例加载低周疲劳寿命估算方法

同济大学学报（自然科学版） 2004年第12期32卷 1637-1641页

作者：何国求陈成澍丁向群徐瑞萱同济大学材料科学与工程学院

利用对 316L不锈钢多轴非比例加载低周疲劳的试验结果 ,对现有的多轴低周疲劳寿命估算方法进行了讨论 ,基于 316L不锈钢非比例加载低周疲劳的微观机理 ,选择最大剪应变以及应变路径的非比例度作为损伤参量 ,建立了基于临界面方法的新的... 详细信息

利用对 316L不锈钢多轴非比例加载低周疲劳的试验结果 ,对现有的多轴低周疲劳寿命估算方法进行了讨论 ,基于 316L不锈钢非比例加载低周疲劳的微观机理 ,选择最大剪应变以及应变路径的非比例度作为损伤参量 ,建立了基于临界面方法的新的非比例加载低周疲劳寿命估算公式 ,利用新的非比例加载低周疲劳寿命估算公式对寿命的预测结果表明 :新的寿命估算公式对剪切型破坏的 316L与 316LN不锈钢及拉伸型破坏的 30 4不锈钢非比例加载低周疲劳寿命预言能力比现有的临界面方法精确 .

关键词：金属材料非比例加载低周疲劳寿命估算