检索结果-南通市图书馆

Fifth International Conference on Surface Engineering

作者： Jiang-Bo Cheng1 2 Bin-Shi Xu2 Yi-Xiong Wu1 zheng-Jun Liu3 Xiu-Bing Liang2 1 school of materials science and Engineering Shanghai Jiao Tong university Shanghai china 2 National Key Laboratory for Remanufacturing beijing china 3 school of materials science and Engineering Shenyang university of technology Shenyang china

A series of iron-based composite coatings were fabricated by using plasma transferred arc weld surfacing process with externally longitudinal magnetic *** microstructure,microhardness of these coatings were characterized by using optical micrograph（OM）,scanning electron micrograph（SEM）,energy dispersive X-ray analysis（EDS）,X-ray diffraction（XRD）,Rockwell microhardness *** wear resistance of the coatings was evaluated by using wet sand rubber wheel abrasion *** results showed that,when the magnetic filed was not applied,the strip-like and hexagonal-like（Fe,Cr）7C3 carbides with a small volume fraction were non-uniformly distributed in the ***,when the magnetic filed was applied,the microstructure of the coating was mainly γ-Fe as the matrix which was reinforced by strip-like or hexagonal-like（Fe,Cr）7C3 and Cr7C3 *** increasing the magnetic current,the amount of hexagonal-like（Fe,Cr）7C3 carbide reinforced phase increased firstly,reached a local maximum,and then *** local maximum of reinforced phase was found when the magnitude of the magnetic current was *** such a case,the hard phases in the coatings were uniformly distributed and the excellent abrasive wear resistance would be *** further increasing the magnetic current,it was interesting to find that many agglomerated particles existed in the *** main constituent phase of the agglomerated particles was（Fe,Cr）7C3 *** existence of the agglomerated microstructure was harmful to the mechanical properties of the coatings,resulting in increment of the wear weight loss.

关键词： plasma transferred arc weld surfacing electromagnetic stirring microstructure wear resistance

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Improvement in hydrogen storage performance of MgH_(2) by vanadium doped with ZIF-8 derived a single-atom catalyst V-N-C

引用

Rare Metals 2024年第6期43卷 2623-2635页

作者： Fei-Fan Hong Wei-Tao Shi Ruo-Lin Zhao Yi Fan Zi-Qi Liu Si-Zhi ding Hai-Zhen Liu Wen-zheng Zhou Jin Guo Zhi-Qiang Lan Guangxi Novel Battery materials Research Center of Engineering technology and Center on Nanoenergy Research Guangxi Colleges and Universities Key Laboratory of Blue Energy and Systems IntegrationCarbon Peak and Neutrality Science and Technology Development InstituteSchool of Physical Science and TechnologyGuangxi UniversityNanning 530004China Nanning Engineering technology Research Center for Power Transmission System of New Energy Vehicle Transportation CollegeNanning UniversityNanning 530200China

Herein,the successful preparation of a singleatom catalyst V-N-C using vanadium-doped zeolitic imidazolate framework(ZIF)-8 as a precursor is *** experimental results showed that the V-N-C had a good promoting effect on the hydrogen storage performance of MgH_(2),and the optimal addition amount of V-N-C was 10wt%.The hydrogenation and dehydrogenation apparent activation energies of 10 wt%V-N-C-catalyzed MgH_(2)were reduced by 44.9 and 53.5 kJ·mol^(-1),respectively,compared to those of additive-free MgH_(2).The 10 wt%V-N-C-catalyzed MgH_(2)could reabsorb 5.92 wt%of hydrogen in 50 min at 150℃,with a capacity retention rate of 99.1%after 30 cycles of hydrogen absorption and *** analysis showed that V-N-C was partially transformed into VN and metallic V when it was milled with MgH_(2);the in-situ-formed VN and metallic V played an important role in improving the hydrogen storage performance of MgH_(2).This approach provides a potential solution for obtaining high-performance Mg-based hydrogen storage materials through synergistic interactions between V,N and C.

关键词： MgH_(2) Hydrogen storage materials Catalyst Hydrogen storage perormance

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Enhancing immunotherapy efficacy against MHC-I deficient triple-negative breast cancer using LCL161-loaded macrophage membranedecorated nanoparticles

引用

Acta Pharmaceutica Sinica B 2024年第7期14卷 3218-3231页

作者： Wen Zhang Yihui Zhai Ying Cai Xiang Gong Yunxuan Jiang Rong Rong Chao zheng Binyu Zhu Helen He Zhu hao Wang Yaping Li Pengcheng Zhang china State Institute of Pharmaceutical Industry Shanghai 201203China State Key Laboratory of Drug Research&Center of Pharmaceutics Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China school of Biomedical Engineering&State Key Laboratory of Advanced Medical materials and Devices ShanghaiTech UniversityShanghai 201210China school of Chinese Materia Medica Nanjing University of Chinese MedicineNanjing 210023China Yantai Institute of Materia Medica Shandong 264000China State Key Laboratory of Oncogenes and Related Genes Renji-Med-X Stem Cell Research CenterDepartment of UrologyRen Ji HospitalSchool of Medicine and School of Biomedical EngineeringShanghai Jiao Tong UniversityShanghai 200127China university of Chinese Academy of sciences Beijing 100049China

Current cytotoxic T lymphocyte(CTL)activating immunotherapy requires a major histocompatibility complex I(MHC-I)-mediated presentation of tumor-associated antigens,which malfunctions in around half of patients with triple-negative breast cancer(TNBC).Here,we create a LCL161-loaded macrophage membrane decorated nanoparticle(LMN)for immunotherapy of MHC-I-deficient *** on the macrophage membrane helps LMNs recognize CD47-expressing cancer cells for targeted delivery of LCL161,which induces the release of high mobility group protein 1 and proinflammatory cytokines from cancer *** released cytokines and high mobility group protein 1 activate antitumor immunity by increasing the intratumoral density of the phagocytic macrophage subtype by 15 times and elevating the intratumoral concentration of CTL lymphotoxin by 4.6 *** also block CD47-mediated phagocytosis *** inhibit the growth of MHC-I-deficient TNBC tumors,as well as those resistant to combined therapy of anti-PDL1 antibody and albumin-bound paclitaxel,and prolong the survival of animals,during which process CTLs also play important *** macrophage membrane-decorated nanoparticle presents a generalizable platform for increasing macrophagemediated antitumor immunity for effective immunotherapy of MHC-I-deficient cancers.

关键词： MHC-I deficiency Macrophage CD47 Immunotherapy Triple-negative breast cancer Phagocytosis Immune checkpoint Innate immunity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Microscopic phase-field simulation including elastic strain energy for early precipitation process of Ni-Al alloys with medium Al content

引用

Progress in Natural science:materials International 2005年第12期15卷 1104-1109页

作者： LU Yanli,CHEN zheng,LI Yongsheng,WANG Yongxin and CHU Zhong State Key Laboratory of Solidification Processing,school of materials science and Engineering,Northwestern Polytechnical university,Xi’an 710072,china State Key Laboratory of Solidification Processing School of Materials Science and Engineering Northwestern Polytechnical University Xi'an 710072 China

The early precipitation process of Ni-Al alloy was studied on the atomic scale based on the microscopic phase-field kinetic *** investigated the effect of elastic strain energy on precipitation mechanism and morphological evolution of the *** results show that at the early stage of precipitation,γ’ ordered phase presents non-directional and irregular shape during the process of aging,the γ’ ordered phases change into the quadrate shape and their orientations become more obvious; at the later stage,the γ’ precipitates present quadrate shape with round corner and align along the [100] and [010] *** mechanism of early precipitation for Ni-13at.%A1 alloy is the mixed mechanism of non-classical nucleation growth and spinodal decomposition and near to non-classical nucle-ation growth,and the mechanism of early precipitation for Ni-15.8at.% Al alloy is the mixed mechanism of non-classical nucleation growth and spinodal decomposition and near to spinodal decomposition.

关键词： Ni-Al alloy early precipitation microscopic phase-field simulation elastic strain energy

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Formation and evolution mechanisms of large-clusters during rapid solidification process of liquid metal Al

引用

science china(Physics,Mechanics & Astronomy) 2005年第1期48卷 101-112页

作者： LIU Rangsu, DONG Kejun, LIU Fengxiang, zheng Caixing, LIU Hairong & LI Jiyong Department of Applied Physics, Hunan university, Changsha 410082, china College of materials science and Engineering, Hunan university, Changsha 410082, china College of Chemistry and Chemical Engineering, Hunan university, Changsha 410082, china Department of Applied Physics Hunan University Changsha 410082 China College of materials science and Engineering Hunan University Changsha 410082 China College of Chemistry and Chemical Engineering Hunan University Changsha 410082 China

A molecular dynamics simulation study has been performed for the formation and evolution characteristics of nano-clusters in a large-scale system consisting of 400000 atoms of liquid metal Al. The center-atom method combined with pair-bond analysis technique and cluster-type index method (CTIM) has been applied here to describe the structural configurations of various basic clusters. It is demonstrated that both the 1551 bond-type and the icosahedral cluster (12 0 12 0) constructed by 1551 bond-types are dominant among all the bond-types and cluster-types, respectively, in the system and play a critical role in the microstructure transitions of liquid metal Al. The nano-clusters (containing up to 150 atoms) are formed by the combination of some middle and small clusters with distinctly different sizes, through mutual competition by unceasing annex and evolution in a seesaw manner (in turn of obtaining and losing),which do not occur as the multi-shell structures accumulated with an atom as the center and the surrounding atoms are arranged according to a certain rule. This is the essential distinction of nano-cluster in liquid metal from those obtained by gaseous deposition, ionic spray methods, and so on. Though the nano-clusters differ from each other in shape and size, all of them possess protruding corners that could become the starting points of various dendrite structures in the solidification processes of liquid metals.

关键词： liquid metal, solidification process, large-cluster configuration, evolution mechanism, computer simulation.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Key points on temperature change of the past 2000 years in china

引用

Progress in Natural science:materials International 2004年第8期 82-89页

作者： GE Quansheng 1, zheng Jingyun 1*, MAN Zhimin 2, FANG Xiuqi 3,1 and ZHANG Piyuan 1(1. Institute of Geographic sciences and Natural Resources Research, Chinese Academy of sciences, beijing 100101, china 2. Institute of Chinese History Geography, Fudan university, Shanghai 200433, china 3. school of Geography, beijing Normal university, beijing 100875, china) Institute of Geographic sciences and Natural Resources Research，Chinese Academy of sciences，beijing 100101，china Institute of Chinese History Geography，Fudan university，Shanghai 200433，china school of Geography，beijing Normal university，beijing 100875，china Institute of Geographic sciences and Natural Resources Research，Chinese Academy of sciences，beijing 100101，china

Temperature change of the past 2000 years in china is discussed based on the winter half-year temperature series of the past 2000 years in eastern china reconstructed recently, and other related studies. The main conclusions are as follows: (1) The Little Ice Age (LIA) in china began in the early of the 14th century (1320s) and ended in the beginning of the 20th century (1910s), which was composed of four evident cold stages and three short warming stages. The cold period in the Wei, Jin and South-North dynasties (210s～560s) was the only one comparable with LIA for the past 2000 years. (2) The Medieval Warm Period (MWP) in china began in the 930s and ended in the 1310s, which was composed of two warm stages over 100 years and a cold stage less than 100 years. (3) The climate in the Sui and Tang dynasties should be divided into two stages: the climate in the 570s～770s was as warm as that in the 20th century; while the temperature in the 780s～920s was lower than that in the 1950s～1970s. (4) In eastern china as a whole, winter half-year temperature variation with over 1 ℃ occurred between the cold and warm stages on centennial scale, while the changing rate exceeded 1.0 ℃ per century. (5) There exists an about 1350-year periodicity in the historical temperature change. Inferred from the periodicity, the most likely historical analogue for the warming in the 20th century is the warm stage of the Sui and Tang dynasties (570s～770s), instead of the Medieval Warm Period. (6) Although it was critically warm, the temperature of the 20th century in eastern china is still within the threshold of the variability of the last 2000 years.

关键词： eastern china past 2000 years temperature change.

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Microglial glutaminase 1 mediates chronic restraint stress-induced depression-like behaviors and synaptic damages

引用

Signal Transduction and Targeted Therapy 2024年第1期9卷 40-43页

作者： Huili Chen Shengyang Fu Xiangyu Li Meng Shi Jiazhen Qian Shu Zhao Ping Yuan Lu ding Xiaohuan Xia Jialin C.zheng Center for Translational Neurodegeneration and Regenerative Therapy Tongji Hospital affiliated to Tongji University School of Medicine200065 ShanghaiChina Department of Cardio-Pulmonary Circulation Shanghai Pulmonary HospitalSchool of MedicineTongji UniversityShanghaiChina Translational Research Institute of Brain and Brain-Like Intelligence Shanghai Fourth People’s Hospital affiliated to Tongji University School of Medicine200434 ShanghaiChina

Dear Editor,Major depressive disorder(MDD)is one of the most common psychiatric illnesses that significantly increase the risk of suicide.1 Stress-triggered dysfunctions of microglia have been identified as a commonly occurred pathological feature of MDD.1–3 Microglial dysfunction contributes to the pathogenesis of MDD via immunoresponses/neuroinflammation-mediated neural damage and pathological synapse loss-mediated neural circuit disruption.1 Although the involvement of microglia in MDD has been widely investigated,the molecular mechanisms underlying microglial dysfunction remain largely ***,we identified glutaminase 1(Gls1)as one key protein that participates in microglial dysfunction.4–6 Gls1 catalyzes the hydrolysis of glutamine to produce glutamate in the brain.4 Besides its well-known role in excitatory neurotoxicity,we found Gls1 up-regulation in microglia in animal models of Alzheimer’s disease and ischemic stroke.4,7 Gls1 activates microglia to overproduce cytokines and release inflammatory extracellular vesicles,therefore leading to neuroinflammation in animal models of Alzheimer’s disease and ischemic stroke.4–6 More importantly,Gls1 has been found to be up-regulated in the brains of MDD patients,and microglial Gls1 deficiency mitigated LPS-induced depression-like behaviors.8 However,LPS exposure is not an appropriate model to mimic MDD phenotypes,leaving the involvement of Gls1 in MDD an undetermined question.

关键词： involvement inflammation media

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hydrogen peroxide sulfenylates and inhibits the photorespiratory enzyme PGLP1 to modulate plant thermotolerance

引用

Plant Communications 2024年第6期5卷 139-153页

作者： zheng-Wei Fu Feng ding Bing-Lei Zhang Wen-Cheng Liu Zi-Hong Huang Shi-Hang Fan Yu-Rui Feng Ying-Tang Lu Wei Hua Key Laboratory of Biology and Genetic Improvement of Oil Crops Ministry of Agriculture and Rural AffairsOil Crops Research Institute of the Chinese Academy of Agricultural SciencesWuhan 430062China State Key Laboratory of Hybrid Rice College of Life SciencesWuhan UniversityWuhan 430072China school of Landscape and Ecological Engineering Hebei University of EngineeringHandan 056038China State Key Laboratory of Crop Stress Adaptation and Improvement School of Life SciencesHenan UniversityKaifeng 475004China Hubei Hongshan Laboratory Wuhan 430070China

Climate change is resulting in more frequent and rapidly changing temperatures at both extremes that severely affect the growth and production of plants,particularly *** stress caused by high temperatures is one of the most damaging factors for ***,the role of hydrogen peroxide(H_(2)O_(2))in modulating plant thermotolerance is largely unknown,and the regulation of photorespiration essential for C3 species remains to be fully ***,we report that heat stress promotes H2O2 accumulation in chloroplasts and that H2O2 stimulates sulfenylation of the chloroplast-localized photorespiratory enzyme 2-phosphoglycolate phosphatase 1(PGLP1)at cysteine 86,inhibiting its activity and promoting the accumulation of the toxic metabolite *** also demonstrate that PGLP1 has a positive function in plant thermotolerance,as PGLP1 antisense lines have greater heat sensitivity and PGLP1-overexpressing plants have higher heat-stress tolerance than the wild ***,our results demonstrate that heat-induced H2O2 in chloroplasts sulfenylates and inhibits PGLP1 to modulate plant ***,targeting CATALASE2 to chloroplasts can largely prevent the heatinduced overaccumulation of H2O2 and the sulfenylation of PGLP1,thus conferring thermotolerance without a plant growth *** findings reveal that heat-induced H2O2 in chloroplasts is important for heat-caused plant damage.

关键词： heat stress photorespiration hydrogen peroxide PGLP1 2-phosphoglycolate

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

(Sr_(1-x)M_x)Al_2O)4(M=Ca,Ba)∶Eu发光材料的研究

引用

稀土 2004年第6期25卷 45-47,59页

作者：顾玉芬靳正国田勃然天津大学材料学院

以SrAl2O4∶Eu发光材料为基础,通过对基质的部分修饰,合成了(Sr1-xMx)Al2O4(M=Ca,Ba)∶Eu磷光体,并利用XRD对其晶体结构进行了研究,结果表明:加入Ca后,原来在室温下稳定存在的属于单斜晶系的鳞石英结构SrAl2O4相逐渐变成六方晶系,证明C... 详细信息

以SrAl2O4∶Eu发光材料为基础,通过对基质的部分修饰,合成了(Sr1-xMx)Al2O4(M=Ca,Ba)∶Eu磷光体,并利用XRD对其晶体结构进行了研究,结果表明:加入Ca后,原来在室温下稳定存在的属于单斜晶系的鳞石英结构SrAl2O4相逐渐变成六方晶系,证明Ca有稳定六方相的作用,而加入Ba晶形则不发生改变。同时研究了该发光粉的发射光谱,讨论了Ca和Ba的引入对发光性能的影响。

关键词： SrAl2O4 晶形转变磷光体

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Experimental Research on Nb bearing X60 Pipeline Steel Produced by CSP Process

Experimental Research on Nb bearing X60 Pipeline Steel Produ...

引用

2006年薄板坯连铸连轧国际研讨会

作者： LIU Ya-zheng1, HE Jian-zhong2, WANG Xue-lian2, LIU Li-bin1, LI Yang1 (1. school of materials science and Engineering, university of science and technology beijing, beijing 100083, china 2. Baotou Iron & Steel (Group) Co. Ltd., Baotou 014010, china)

Nb bearing X60 pipeline steel has been successfully developed on the CSP line in Baogang Group. With the mixed grain structure, the strengthening and toughening mechanism of X60 pipeline steel has bee

关键词： Nb bearing X60 pipeline steel CSP dynamic recrystallization precipitation

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：