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A PCA-based method for ancestral informative markers selection in structured populations

science china(Life sciences) 2009年第10期52卷 972-976页

作者： ZHANG feng1,3, ZHANG Lei1,3 & DENG Hong-Wen1,2,3 1 Key Laboratory of Biomedical Information engineering of Ministry of Education, institute of molecular Genetics, School of Life science and technology, Xi’an Jiaotong university, Xi’an 710049, china 2 institute of Bioscience and Biotechnology, School of science, Beijing Jiaotong university, Beijing 100044, china 3 Departments of Orthopedic surgery and Basic Medical science, School of Medicine, university of Missouri-Kansas City, Kansas City, MO 64108, USA 1. Key Laboratory of Biomedical Information engineering of Ministry of Education Institute of Molecular Genetics School of Life Science and Technology Xi’an Jiaotong University Xi’an 710049 China 3. Departments of Orthopedic surgery and Basic Medical science School of Medicine University of Missouri-Kansas City Kansas City MO 64108 USA 2. institute of Bioscience and Biotechnology School of Science Beijing Jiaotong University Beijing 100044 China

Identification of population structure can help trace population histories and identify disease genes. Structured association (SA) is a commonly used approach for population structure identification and association mapping. A major issue with SA is that its performance greatly depends on the informa-tiveness and the numbers of ancestral informative markers (AIMs). Present major AIM selection meth-ods mostly require prior individual ancestry information, which is usually not available or uncertain in practice. To address this potential weakness, we herein develop a novel approach for AIM selection based on principle component analysis (PCA), which does not require prior ancestry information of study subjects. Our simulation and real genetic data analysis results suggest that, with equivalent AIMs, PCA-based selected AIMs can significantly increase the accuracy of inferred individual ancestries compared with traditionally randomly selected AIMs. Our method can easily be applied to whole genome data to select a set of highly informative AIMs in population structure, which can then be used to identify potential population structure and correct possible statistical biases caused by population stratification.

关键词： population structure principle component analysis ancestral informative markers

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PREPARATION OF A NOVEL CPE THERMOPLASTIC ELASTOMER VIA IN-SITU CHLORINATING GRAFT COPOLYMERIZATION

PREPARATION OF A NOVEL CPE THERMOPLASTIC ELASTOMER VIA IN-SI...

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40th IUPAC Congress

作者： Xuezhen Zhu 1 Jiruo Zhao 1.2* Ying feng 1 and Qingming Yin 1 1 Key Laboratory of Rubber-Plastics Ministry of Education School of Polymer science and engineering qingdao university of science & technology qingdao 266042 china 2 State Key Laboratory of Polymer Physics and chemistry Changchun institute of Applied chemistry Chinese Academy of sciences Changchun 130022 china

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ANHYDRIDE FUNCTIONALIZATION RESEARCH OF PVC VIA IN-SITU CHLORINATING GRAFT COPOLYMERIZATION

ANHYDRIDE FUNCTIONALIZATION RESEARCH OF PVC VIA IN-SITU CHLO...

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40th IUPAC Congress

作者： Qifu Qin1 Jiruo Zhao1.2 Ying feng1 and Runxin Zhang1 1Key Laboratory of Rubber-Plastics Ministry of Education School of Polymer science and engineering qingdao university of science & technology qingdao 266042 china 2State Key Laboratory of Polymer Physics and chemistry Changchun institute of Applied chemistry Chinese Academy of sciences Changchun 130022 china

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Meroterpenes from endophytic fungus of Scyphiphora hydrophyllacea

Meroterpenes from endophytic fungus of Scyphiphora hydrophyl...

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中国化学会第9届天然有机化学学术会议

作者： Wen-li Mei~(1,+),Bo Zheng~(1,2,+),You-Xing Zhao~1,Hui-Ming Zhong~2,Yan-Bo Zeng~1,Wen-Hua Dong~1,Hao-Fu Dai~(1*) 1 Key Laboratory of Biology and Genetic Resources of Tropical Crops,Ministry of Agriculture,institute of Tropical Bioscience and Biotechnology,Chinese Academy of Tropical Agriculture sciences, Haikou 571101,People''s Republic of china 2 College of chemistry and molecular engineering,qingdao university of science and technology, qingdao,266042,People''s Republic of china.

＜正＞Four new meroterpenes,guignardones F-I（1-4）,together with two known compounds guignardones A（5） and B（6）,were isolated from the endophytic fungus Al {Guignardia sp.) of mangrove plant Scyphiphora *** 2-4 have similar tricyclic skeleton to tricycloalternarene series isolated from some phyto-pathogenic fungi,mainly Alternaria *** A（5） and B（6） with an additional tetrahydrofuran ring in their structure have been isolated from a fungus Guignardia mangiferae associated with Ilex cornuta ***,compound 1 possessed a novel structure,beside an additional

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钢筋混凝土电化学脱盐影响因素的研究

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武汉理工大学学报 2009年第7期31卷 19-21,34页

作者：丁铸邢锋李伟华深圳大学土木工程学院深圳市土木工程耐久性重点实验室深圳518060 中国科学院海洋研究所青岛266071

采用双层钢筋混凝土试件、电流密度2 mA/cm2、饱和氢氧化钙溶液为电介质溶液,研究了脱盐处理过程中水灰比对电化学脱盐效果的影响,以及对混凝土中钢筋腐蚀状态的影响。结果表明,随着脱盐时间延长,混凝土中的氯离子浓度逐渐降低;混凝土... 详细信息

采用双层钢筋混凝土试件、电流密度2 mA/cm2、饱和氢氧化钙溶液为电介质溶液,研究了脱盐处理过程中水灰比对电化学脱盐效果的影响,以及对混凝土中钢筋腐蚀状态的影响。结果表明,随着脱盐时间延长,混凝土中的氯离子浓度逐渐降低;混凝土的水灰比越大,脱盐的效果相对越好。脱盐处理后可使得混凝土中钢筋半电池电位逐渐正移,可使得已经处于锈蚀活化状态的钢筋恢复到非锈蚀活化状态。

关键词：混凝土耐久性电化学脱盐钢筋腐蚀粘结强度

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Identification of Porphyra cell lines (Rhodophyta) by a novel molecular marker system:Sequence-Related Amplified Polymorphism (SRAP)

Identification of Porphyra cell lines (Rhodophyta) by a nove...

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中国海洋湖沼学会藻类学分会第七届会员大会暨第十四次学术讨论会

作者： LX Qiao~(1,2) HY Liu~2 BT Guo~3 YB feng~2 ML Weng~2 JX Dai~1 DL duan~(4*) B Wang~(2*) 1 Department of Life science & technology,Ocean university of china,qingdao 266003,china, 2 The State Key Laboratory of Plant Genomics,institute of Genetics and Developmental Biology Chinese Academy of sciences,Beijing 100101,china 3 College of Life science,Laiyang Agricultural university,qingdao 266109,china 4 institute of Oceanology,Chinese Academv of sciences,qingdao 266071,china.

Sequence-Related Amplified Polymorphism(SRAP)is a newly developed molecular marker technique aimed for the amplification of open reading flames(ORFs).Here in our study,SRAP analytic system was successfully applied in ...

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A new prenylated xanthone from the branches of Calophyllum inophyllum

A new prenylated xanthone from the branches of Calophyllum i...

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海南省药学会二○一○年学术年会

作者： Dai-Jing Wei~(a,b),Wen-Li Mei~a,Hui-Ming Zhong~b,Yan-Bo Zeng~a,Xu-Dong Wu~a,Hao-Fu Dai~(a*) a Key Laboratory of Tropical Crop Biotechnology,Ministry of Agriculture,institute of Tropical Bioscience and Biotechnology,Chinese Academy of Tropical Agricultural sciences,Haikou 571101,china b College of chemistry and molecular engineering,qingdao university of science and technology,qingdao 266042,china

The investigation of chemical constituents from the branches of Calophyllum inophyllum Linn led to the isolation of a new prenylated xanthone,named caloxanthone Q(1),together with three known compounds,2-deprenylrheediaxanthone B(2),jacareubin(3),and 6-deoxyjacareubin(4).Their structures were completely elucidated on the basis of spectroscopic methods(UV,IR,HR-ESI-MS,1D and 2D NMR).

关键词： Clusiaceae Calophyllum inophyllum Linn Prenylated xanthone Caloxanthone Q

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Magnetostratigraphy and paleoenvironmental record of late Cenozoic sediments in the Taiyuan Basin,North china

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Journal of Palaeogeography 2024年第4期13卷 971-992页

作者： Zhi-Qiang feng Qian LI Wei Han Kun-Yuan Ma Yong-Jiang Liu Rong-Zhu Wei Yan-Wei du Yong Lei Guang-Hui Li College of Geoscience and Geomatics engineering Taiyuan University of Technology Shanxi institute of Geological survey Frontiers science Center for Deep Ocean Multispheres and Earth System Key Lab of Submarine Geoscience and Prospecting TechniquesCollege of Manine GeosciencesOcean University of China Laboratory for Marine Mineral Resources Qingdao National Laboratory for Marine Science and Technology College of Resources and Environment Shanxi Agricultural University Department of Information engineering Shanxi University

The Taiyuan Basin is of importance for intraplate tectonic deformation in North china and contains Cenozoic strata with a maximum thickness of 3800 m.A～853.5-m-deep borehole (ZK01) with an overall core recovery rate of 85.09%was drilled at Yuci (37°35'37?N,112°39'47?E) in the central Taiyuan Basin,to obtain high-resolution records of paleomagnetism,paleoclimatic and paleoenvironmental conditions,and depositional environment of the *** obtained magnetic polarity sequence consists of 13 normal and 12 reverse zones,which correspond to C1n-C4An.2n of the geomagnetic polarity time *** data show that the evolution of ZK01 core covers the interval from 8.1 Ma to the present,and the bottoms of Pliocene,Quaternary,and Middle Pleistocene were identified in Taiyuan Basin,with a sedimentary accumulation rate ranging from 62.5 m/Ma to 175.9 m/*** data reveal that the source rocks in the study area underwent intense weathering and the sediments mainly formed in a semi-arid and oxygen-rich *** addition,paleoclimatic changes occurred at～7 Ma,3.8 Ma,and 1.7 Ma,which can be closely related to the tectonic uplift of the Loess Plateau and Tibetan Plateau,as well as the variations in the Asian monsoon and associated regional and global climatic change.

关键词： Taiyuan Basin Core sediment Magnetostratigraphy Climate change Paleoenvironment Quaternary

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一种类Spreadsheet结构的信息汇聚方法

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计算机科学 2010年第5期37卷 134-138页

作者：魏永山韩燕波孙忠林张峰陈欣山东科技大学信息科学与工程学院青岛266510 中国科学院计算技术研究所北京100083

SpreadSheet样式的数据操作具有很好的可用性,但在SpreadSheet结构中如何表示并操纵XML数据以及如何使用复制、粘贴、移动等简单操作表示复杂的XQuery查询是两个难点问题。提出一种基于XML模式的操作表示方法,将复杂的XQuery查询语句分... 详细信息

SpreadSheet样式的数据操作具有很好的可用性,但在SpreadSheet结构中如何表示并操纵XML数据以及如何使用复制、粘贴、移动等简单操作表示复杂的XQuery查询是两个难点问题。提出一种基于XML模式的操作表示方法,将复杂的XQuery查询语句分解为XML模式上的粘贴节点、移动节点等操作,从而可以表示XQuery语言的核心语句FLOWR。在Spreadsheet结构中将XML模式显示为嵌套表格,用户在嵌套表格上的操作转换为XML模式上的操作。使用该方法可以构造多数据源的XQuery查询,并实现了概念验证的原型系统。与当前流行的XQuery查询构造工具相比较,原型系统更适合于无编程经验的最终用户构造XQuery查询。

关键词： Spread Sheet XQuery 信息集成信息资源汇聚

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ISOLATION AND FRACTIONATION OF HEMICELLULOSES FROM SALIX PSAMMOPHILA

ISOLATION AND FRACTIONATION OF HEMICELLULOSES FROM SALIX PSA...

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第十六届木材、纤维及制浆化学国际会议

作者： feng Peng~(1,2),Ning Jia~1,Jing Bian~1,Pai Peng~2, feng Xu~1,and Runcang sun~(1,2*) 1.institute of Biomass chemistry and technology,Beijing Forestry university,Beijing 100083,china 2.State Key Laboratory of Pulp and Paper engineering, South china university of technology,Guangzhou 510640,china.

Water- and alkali-soluble hemicelluloses were isolated with hot water and 10%KOH at 25 CC from dewaxed and delignified Salix psammophila,*** alkali-soluble hemicelluloses were then successively sub-fractioned by neutralization and graded precipitation at final ethanol concentrations of 15%,30%,45%,60%,75%and 90%, *** composition,physico-chemical properties,and structures of eight precipitated hemicellulosic fractions were elucidated by a combination of sugar analysis,molecular determination,FT-IR,H,C 2D HSQC *** was found that water-soluble hemicelluloses were more branched,and had low molecular weights（6060 g/mol）,whereas the alkali-soluble hemicelluloses were less branched,and had high molecular weights（17110-85540 g/mol）,in which xylose and uronic acid are the main sugar *** addition,the less branched hemicelluloses with large molecules were precipitated in lower ethanol percentages,while with the increasing ethanol concentrations,more branched hemicelluloses with low molecular weights were obtained. That is,linear hemicelluloses could be recovered at lower ethanol concentrations,and more branched hemicelluloses could be obtained at the higher ethanol concentrations. Based on the FT-IR,H,C and 2D HSQC NMR studies, the alkali-soluble hemicelluloses had a main structure composed of the（1→4）-linked β-D-xylopyranosyl backbone with 4-O-methyl-α-D-glucuronic acid attached to O-2 of the xylose residues.

关键词： Salix psammophila hemicelluloses alkali fractionation xylans

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