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Genome-wide development of interspecific microsatellite markers for Saccharum officinarum and Saccharum spontaneum

Journal of Integrative Agriculture 2022年第11期21卷 3230-3244页

作者： LIU Lei WANG Heng-bo LI Yi-han CHEN Shu-qi WU Ming-xing dou mei-jie QI Yi-yin FANG Jing-ping ZHANG Ji-sen Center for Genomics and Biotechnology Fujian Provincial Key Laboratory of Haixia Applied Plant Systems BiologyKey Laboratory of GeneticsFujian Agriculture and Forestry UniversityFuzhouFujian 350002P.R.China State Key Lab for Conservation and Utilization of Subtropical Agro-Biological Resources&Guangxi Key Lab for Sugarcane Biology Guangxi UniversityNanning 530004P.R.China College of Life Sciences Fujian Normal UniversityFuzhou 350007P.R.China

Sugarcane has a large,complex,polyploid genome that has hindered the progress of genomic research and molecular marker-assisted *** user-friendly SSR markers have attracted considerable attention owing to their ideal genetic ***,these markers were not characterized and developed at the genome-wide scale due to the previously lacking high-quality chromosome-level assembled sugarcane *** this present study,744305and 361638 candidate SSRs were identified from the genomes of *** and ***,*** verified the reliability of the predicted SSRs by using 1200 interspecific SSR primer pairs to detect polymorphisms among 11 representative accessions of Saccharum,including ***,***,***,and modern sugarcane *** results showed that 660 SSR markers displayed interspecific polymorphisms among these ***,100 SSRs were randomly selected to detect the genetic diversity for 39 representative Saccharum accessions.A total of 320 alleles were generated using 100 polymorphic primers,with each marker ranging from two to seven *** genetic diversity analysis revealed that these accessions were distributed in four main groups,including group I(14 *** accessions),group II(two *** accessions),group III(18 modern sugarcane hybrid accessions),and group IV(five *** accessions).Experimental verification supported the reliability of the SSR markers based on genome-wide *** development of a large number of SSR markers based on wet experiments is valuable for genetic studies,including genetic linkage maps,comparative genome analysis,genome-wide association studies,and marker-assisted selection in Saccharum.

关键词： Saccharum genome-wide simple repeat sequences(SSR) microsatellite molecular markers

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Computed tomography enterography-based radiomics for assessing mucosal healing in patients with small bowel Crohn's disease

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World Journal of Gastroenterology 2025年第3期31卷 62-72页

作者： Hao Ding Yuan-Yuan Fang Wen-jie Fan Chen-Yu Zhang Shao-Fei Wang Jing Hu Wei Han Qiao mei Department of Gastroenterology The First Affiliated Hospital of Anhui Medical UniversityHefei 230022Anhui ProvinceChina Department of Radiation Oncology The First Affiliated Hospital of Anhui Medical UniversityHefei 230022Anhui ProvinceChina Department of Gastroenterology Suzhou First People's HospitalSuzhou 234099Anhui ProvinceChina

BACKGROUND Mucosal healing(MH)is the major therapeutic target for Crohn's disease(CD).As the most commonly involved intestinal segment,small bowel(SB)assessment is crucial for CD ***,it poses a significant challenge due to its limited accessibility through conventional endoscopic *** To establish a noninvasive radiomic model based on computed tomography enterography(CTE)for MH assessment in SBCD *** Seventy-three patients diagnosed with SBCD were included and divided into a training cohort(n=55)and a test cohort(n=18).Radiomic features were obtained from CTE images to establish a radiomic *** demographics were analysed to establish a clinical model.A radiomic-clinical nomogram was constructed by combining significant clinical and radiomic *** diagnostic efficacy and clinical benefit were evaluated via receiver operating characteristic(ROC)curve analysis and decision curve analysis(DCA),*** Of the 73 patients enrolled,25 patients achieved *** radiomic-clinical nomogram had an area under the ROC curve of 0.961(95%confidence interval:0.886-1.000)in the training cohort and 0.958(0.877-1.000)in the test cohort and provided superior clinical benefit to either the clinical or radiomic models alone,as demonstrated by *** These results indicate that the CTE-based radiomic-clinical nomogram is a promising imaging biomarker for MH and serves as a potential noninvasive alternative to enteroscopy for MH assessment in SBCD patients.

关键词： Crohn’s disease Computed tomography enterography Mucosal healing Nomogram Radiomics

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老年COPD合并肺部细菌性感染外周血STING、TBK1、STAT6表达

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中华医院感染学杂志 2023年第2期33卷 166-170页

作者：王娟谷席娟豆美洁杨永霞吕清林聊城大学医院老干部科山东聊城252000 聊城大学医院西校门诊部山东聊城252000 聊城大学医院体检科山东聊城252000 聊城大学医院医技彩超室山东聊城252000

目的探讨老年慢性阻塞性肺疾病(COPD)合并肺部细菌性感染外周血干扰素基因刺激因子(STING)、TANK结合激酶1(TBK1)、信号转导和转录激活因子6(STAT6)的表达。方法选取2019年2月-2021年2月聊城大学医院诊治的96例老年COPD合并肺部细菌性... 详细信息

目的探讨老年慢性阻塞性肺疾病(COPD)合并肺部细菌性感染外周血干扰素基因刺激因子(STING)、TANK结合激酶1(TBK1)、信号转导和转录激活因子6(STAT6)的表达。方法选取2019年2月-2021年2月聊城大学医院诊治的96例老年COPD合并肺部细菌性感染患者为感染组,同期96例老年COPD未合并肺部细菌性感染患者为非感染组,实时荧光聚合酶链式反应(PCR)检测外周血STING、STAT6、TBK1表达及其诊断COPD合并肺部细菌性感染的临床价值。结果感染组外周血STING、TBK1、STAT6表达分别为(25.21±4.69)、(7.06±3.02)、(2.68±0.85)均高于非感染组(P<0.05);重度感染组患者外周血STING、TBK1、STAT6表达均高于轻中度感染组(P<0.05);受试者工作特征(ROC)曲线分析显示,STING、TBK1、STAT6联合预测COPD合并肺部细菌性感染的曲线下面积为0.902,敏感度为89.66%,特异度为74.63%。结论老年COPD合并肺部细菌性感染患者外周血STING、TBK1、STAT6表达升高,三者联合预测肺部感染的诊断效能较好,对临床诊断和治疗有一定的指导价值。

关键词：老年慢性阻塞性肺疾病细菌性感染外周血干扰素基因刺激因子 TANK结合激酶1 信号转导和转录激活因子6 诊断价值

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Asymptotic Behaviors for Critical Branching Processes with Immigration

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Acta Mathematica Sinica,English Series 2019年第4期35卷 537-549页

作者： dou dou LI mei ZHANG School of Mathematical Sciences Laboratory of Mathematics and Complex SystemsBeijing Normal University

In this paper, we investigate the asymptotic behaviors of the critical branching process with immigration {Z_n, n ≥ 0}. First we get some estimation for the probability generating function of Zn. Based on it, we get a large deviation for Z_(n+1)/Z_n. Lower and upper deviations for Zn are also studied. As a by-product, an upper deviation for max_(1≤i≤n) Z_i is obtained.

关键词： Critical branching process immigration large deviations

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MOFs in Emerging Solar Cells

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Chinese Journal of Chemistry 2023年第6期41卷 695-709页

作者： jie dou Qi Chen Beijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications Experimental Centerof Advanced MaterialsSchool of Materials Science&EngineeringBeijing Institute of TechnologyBeijing100081China Bejing Instituteof Technology Chongqing Innovation Center Chongqing 404100China

Metal-organic framework(MOF)materials have attracted intense scientific interest in the solar cell research community owing to their unique physiochemical properties and various preparation *** photovoltaic performance and stability of resultant optoelectronic devices can also be improved by adopting MOF *** review pays close attention to the summary and generalization of recent representative achievements in solar cells by utilizing MOFs,including dye-sensitized solar cells,perovskite solar cells,organic solar cells,and so on.

关键词： MOFs Synthetic methods Solar cells Photochemistry Sustainable chemistry Green chemistry

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Zinc Stannate Nanostructures for Energy Conversion

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Chinese Journal of Chemistry 2021年第2期39卷 367-380页

作者： jie dou Qi Chen Beijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications Experimental Center of Advanced MaterialsSchool of Materials Science&EngineeringBeijing Institute of TechnologyBeijing100081 China Beijing Institute of Technology Chongqing Innovation Center Chongqing 4004100Beijing100081 China

To date,ternary metal oxide semiconductor materials have attracted extensive attention worldwide due to their unique optoelectronic *** a classical ternary oxide,Zn2SnO4 is featured with the high electron mobility,wide band gap,negligible visible light absorption and tailorable electronic band ***,it is an ideal material for practical use in solar cells,lithium batteries,sensors,and *** this review,we summarize the recent research progress of this material with the focus on the synthesis methods,nanostructures,and the resulting effects on the crystal structure,optical properties,and photoelectrochemical ***,their potential applications in different devices are highlighted and carefully discussed.

关键词： Zinc stannate Synthesis design Nanostructures Applications Energy conversion

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Limit Theorems for Critical Galton-Watson Processes with Immigration Stopped at Zero

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Acta Mathematica Sinica,English Series 2024年第2期40卷 435-450页

作者： dou dou LI mei ZHANG Xian Yu ZHANG College of Statistics and Data Science Faculty of ScienceBeijing University of TechnologyBeijing 100124P.R.China Laboratory of Mathematics and Complex Systems(Ministry of Education) School of Mathematical SciencesBeijing Normal UniversityBeijing 100875P.R.China

In this paper,we consider a critical Galton-Watson branching process with immigration stopped at zero *** precise estimation on the probability generating function of the n-th population are obtained,and the tail prob... 详细信息

关键词： Branching immigration critical life period limit theorems

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Multi-Objective Cooperative Salvo Attack Against Group Target

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Journal of Systems Science & Complexity 2018年第1期31卷 244-261页

作者： ZENG jie dou Lihua XIN Bin School of Automation State Key Laboratory of Intelligent Control and Decision of Complex SystemsBeijing Advanced Innovation Center for Intelligent Robots and Systems Beijing Institute of Technology

This paper proposes a solution for the problem of cooperative salvo attack of multiple cruise missiles against targets in a group. Synchronization of the arrival time of missiles to hit their common target, minimizing the time consumption of attack and maximizing the expected damage to group targets are taken into consideration simultaneously. These operational objectives result in a hierarchical mixed-variable optimization problem which includes two types of subproblems, namely the multi-objective missile-target assignment（MOMTA） problem at the upper level and the time-optimal coordinated path planning（TOCPP） problems at the lower level. In order to solve the challenging problem, a recently proposed coordinated path planning method is employed to solve the TOCPP problems to achieve the soonest salvo attack against each target. With the aim of finding a more competent solver for MOMTA, three state-of-the-art multi-objective optimization methods（MOMs）,namely NSGA-II, MOEA/D and DMOEA-εC, are adopted. Finally, a typical example is used to demonstrate the advantage of the proposed method. A simple rule-based method is also employed for comparison. Comparative results show that DMOEA-εC is the best choice among the three MOMs for solving the MOMTA problem. The combination of DMOEA-εC for MOMTA and the coordinated path planning method for TOCPP can generate obviously better salvo attack schemes than the rule-based method.

关键词： Coordinated path planning missile-target assignment multi-missile salvo attack multiobjective optimization

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A joint mid-course and terminal course cooperative guidance law for multi-missile salvo attack

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Chinese Journal of Aeronautics 2018年第6期31卷 1311-1326页

作者： jie ZENG Lihua dou Bin XIN School of Automation Beijing Institute of Technology Beijing 100081 China State Key Laboratory of Intelligent Control and Decision of-Complex Systems Beijing 100081 China

Salvo attacking a surface target by multiple missiles is an effective tactic to enhance the lethality and penetrate the defense system. However, existing cooperative guidance laws in the midcourse or terminal course are not suitable for long-and medium-range missiles or stand-off attacking. Because the initial conditions of cooperative terminal guidance that are generally generated from the mid-course flight may not lead to a successful cooperative terminal guidance without proper mid-course flight adjustment. Meanwhile, cooperative guidance in the mid-course cannot solely guarantee the accuracy of a simultaneous arrival of multiple missiles. Therefore, a joint mid-course and terminal course cooperative guidance law is developed. By building a distinct leader-follower framework, this paper proposes an efficient coordinated Dubins path planning method to synchronize the arrival time of all engaged missiles in the mid-course flight. The planned flight can generate proper initial conditions for cooperative terminal guidance, and also benefit an earliest simultaneous arrival. In the terminal course, an existing cooperative proportional navigation guidance law guides all the engaged missiles to arrive at a target accurately and *** integrated guidance law for an intuitive application is summarized. Simulations demonstrate that the proposed method can generate fast and accurate salvo attack.

关键词： Cooperative systems Dubins path Mid-course flight Missile guidance Salvo attack

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Study on carbon emission calculation method and carbon reduction indexes of urban building stock

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Science China(Technological Sciences) 2024年第9期67卷 2706-2726页

作者： YANG Liu ZHANG Nan LU mei LUO ZhiXing dou mei State Key Laboratory of Green Building Xi’an University of Architecture and TechnologyXi’an 710055China School of Architecture Xi’an University of Architecture and TechnologyXi’an 710055China School of Language Literature and LawXi’an University of Architecture and TechnologyXi’an 710055China School of Management Xi’an University of Architecture and TechnologyXi’an 710055China China Southwest Architectural Design and Research Institute Corp.Ltd. Chengdu 610041China

Carbon emissions associated with buildings are a major source of urban emissions. To put forward the methods and strategies to curb carbon emissions from urban building stock, it is not only necessary to establish a carbon emission calculation method for fine statistical analysis, but also to evaluate carbon emissions of urban planning schemes with applicable indexes. Currently,researches mainly focus on carbon emissions of individual buildings. When expanded to urban building stock, the calculation faces the lack of basic data, inadequate spatial analysis and unspecific carbon reduction indexes. Therefore, this study proposes a bottom-up calculation method for urban building stock, conducts spatial analysis based on carbon balance of urban grids, reveals the coupling mechanism between urban carbon reduction indexes and grid carbon emissions, and systematically establishes a carbon-reduction-oriented urban planning method that comprises calculation, analysis and evaluation, which is applied to Xi'an,China. This study provides a theoretical reference for cities to formulate carbon reduction targets and implement planning strategies by evaluating and predicting carbon emissions from urban building stock.

关键词： carbon emissions urban building stock calculation method carbon reduction index

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