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Optimization of territorial space layout in China

Journal of Geographical Sciences 2024年第9期34卷 1719-1738页

作者： dong yin JIN Gui DENG Xiangzheng Key Laboratory for Humid Subtropical Eco-Geographical Processes of the Ministry of Education Fujian Normal UniversityFuzhou 350007China School of Geographical Sciences Fujian Normal UniversityFuzhou 350007China School of Economics and Management China University of GeosciencesWuhan 430079China Key Laboratory of Land Surface Pattern and Simulation Institute of Geographic Sciences and Natural Resources ResearchCASBeijing 100101China College of Resources and Environment University of Chinese Academy of SciencesBeijing 101408China

The evolution of territorial space is intrinsically linked to economic growth, societal welfare, and ecological preservation. In the context of escalating spatial conflicts and stringent resource limitations, resource efficiency has emerged as a fundamental pillar for the scientific optimization of territorial space layout. Drawing upon resource efficiency metrics from cities nationwide, this study constructs scenarios for territorial space development and conservation, assesses developmental capacity under varying preferences, and subsequently delineates strategic blueprints using an integrated “point-axis-area” approach. The findings reveal the following:(1) Resource efficiency in China has witnessed a consistent uptick, yet remains modest overall, with marked regional disparities.(2) Throughout the investigation period, developmental capacity has seen progressive enhancement, with a pronounced capacity in scenarios favoring development, radiating axially from urban conglomerates.(3) The layout of pivotal points and developmental axes has transitioned from a “tri-pillar” to a diamond configuration, with the coastal corridor, Harbin-Beijing-Guangzhou corridor, and the corridor along the Yangtze River standing out.(4) Strategic points progressively converge along key axes, whereas dominant regions exhibit clear differentiation on either side of the Hu Huanyong Line. By integrating elements of the territorial spatial structure,this paper proposes blueprints for “five horizontal and three vertical zones with eight cores and three areas,” “four horizontal and three vertical zones with six cores and three areas,”and “three horizontal and four vertical zones with five cores and three areas,” corresponding to scenarios of prioritizing development, status quo maintenance, and prioritizing conservation, respectively. The outcomes of this research offer a technical foundation and theoretical guidance for the pursuit of high-quality territorial space development and a vision

关键词： territorial space resource efficiency development and conservation developmental capacity territorial space blueprints China

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The evolution analysis of agricultural global value chains

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Ecological Economy 2024年第2期20卷 178-187页

作者： dong yin-guo ZHOU Xin-yi DU Jian School of Business East China University of Science and TechnologyShanghai 200237CHINA

With the Uruguay Round bringing agricultural trade into multilateral regulation,the major countries have actively participated in agricultural global value chains(AGVC)and occupied an important position according to their comparative *** bilateral agricultural trade data of 66 countries based on the OECD Inter-Country-Input-Output Tables(OECD ICIO)from 2010 to 2018,this study applies social network analysis indicators to measure each country’s eigenvector centrality within AGVC and to examine the current global agricultural trade patterns,with particular attention to the changes in the status of world powers within *** main findings are as follows:first,with the multilateral and regional trade liberalization,growing numbers of developing nations,including China and India,are engaging in international agricultural trade,which contributes to its diversification;second,as AGVC develops,the structure of global agricultural trade networks has become more decentralized and *** is evidenced by the emergence of additional central nodes,and large nations like the United States,which formerly held the most central position as indicated by a drop in its centrality,are becoming less dominant.

关键词： agricultural global value chains centrality indicators world powers

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中国国土空间布局优化研究

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地理学报 2024年第3期79卷 672-687页

作者：董寅金贵邓祥征福建师范大学湿润亚热带生态地理过程教育部重点实验室福州350007 福建师范大学地理科学学院福州350007 中国地质大学(武汉)经济管理学院武汉430074 中国科学院地理科学与资源研究所中国科学院陆地表层格局与模拟重点实验室北京100101 中国科学院大学资源与环境学院北京101408

国土空间发展格局事关经济发展、社会福祉与生态安全,而资源效率成为空间冲突加剧、资源约束趋紧背景下科学优化国土空间布局的基础支撑。本文基于全国市域国土资源效率值设计国土空间开发保护情景方案并评价不同偏好下的国土空间发展潜... 详细信息

国土空间发展格局事关经济发展、社会福祉与生态安全,而资源效率成为空间冲突加剧、资源约束趋紧背景下科学优化国土空间布局的基础支撑。本文基于全国市域国土资源效率值设计国土空间开发保护情景方案并评价不同偏好下的国土空间发展潜力,进而定量刻画“点—轴—面”一体化的国土空间布局蓝图。结果表明:(1)中国国土资源效率稳步上升但整体水平偏低,区域间发展不均衡。(2)研究期内中国国土空间发展潜力持续提升,开发导向下潜力水平相较更高,且不同情景下潜力高值区围绕城市群地区向外轴向扩散。(3)中心点与发展轴线的分布格局经历了由“三足鼎立”向菱形结构演化的过程,其中沿海通道、京哈—京广通道及沿江通道的主体地位突出。(4)战略点向关键轴线有序集聚,优势区在胡焕庸线两侧呈明显分化。组合国土空间结构要素分别形成开发优先、维持现状与保护优先3类情景下“五横三纵,八核三区”“四横三纵,六核三区”与“三横四纵,五核三区”的国土空间布局蓝图。本文研究结果可为实现高质量国土空间发展格局与美丽国土愿景提供技术依据和理论支撑。

关键词：国土空间资源效率开发保护发展潜力布局蓝图中国

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Embryo Transfer Strategies for Women with Recurrent Implantation Failure During the Frozen-thawed Embryo Transfer Cycles:Sequential Embryo Transfer or Double-blastocyst Transfer?

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Current Medical Science 2024年第1期44卷 212-222页

作者： Qiao-hang ZHAO Yu-wei SONG Jian CHEN Xiang ZHOU Ji-lai XIE Qiu-ping YAO Qi-yin dong Chun FENG Li-ming ZHOU Wei-ping FU Min JIN The Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou 310052China Jiaxing Maternity and Child Health Care Hospital Jiaxing 314051China Huzhou Maternity and Child Care Hospital Huzhou 313002China Ningbo Women and Children's Hospital Ningbo 315000China

Objective Both sequential embryo transfer(SeET)and double-blastocyst transfer(DBT)can serve as embryo transfer strategies for women with recurrent implantation failure(RIF).This study aims to compare the effects of SeET and DBT on pregnancy *** Totally,261 frozen-thawed embryo transfer cycles of 243 RIF women were included in this multicenter retrospective *** to different embryo quality and transfer strategies,they were divided into four groups:group A,good-quality SeET(GQ-SeET,n=38 cycles);group B,poor-quality or mixed-quality SeET(PQ/MQ-SeET,n=31 cycles);group C,good-quality DBT(GQ-DBT,n=121 cycles);and group D,poor-quality or mixed-quality DBT(PQ/MQ-DBT,n=71 cycles).The main outcome,clinical pregnancy rate,was compared,and the generalized estimating equation(GEE)model was used to correct potential confounders that might impact pregnancy *** GQ-DBT achieved a significantly higher clinical pregnancy rate(aOR 2.588,95%CI 1.267–5.284,P=0.009)and live birth rate(aOR 3.082,95%CI 1.482–6.412,P=0.003)than PQ/***,the clinical pregnancy rate was significantly higher in GQ-SeET than in PQ/MQ-SeET(aOR 4.047,95%CI 1.218–13.450,P=0.023).The pregnancy outcomes of GQ-SeET were not significantly different from those of GQ-DBT,and the same results were found between PQ/MQ-SeET and PQ/*** SeET relative to DBT did not seem to improve pregnancy outcomes for RIF patients if the embryo quality was comparable between the two *** clinical pregnancy outcomes could be obtained by transferring good-quality embryos,no matter whether in SeET or *** quality plays a more important role in pregnancy outcomes for RIF patients.

关键词： recurrent implantation failure sequential embryo transfer frozen-thawed embryo transfer embryo transfer strategies

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Transcription factor EHF interacting with coactivator AJUBA aggravates malignancy and acts as a therapeutic target for gastroesophageal adenocarcinoma

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Acta Pharmaceutica Sinica B 2024年第5期14卷 2119-2136页

作者： Li Peng Yanyi Jiang Hengxing Chen Yongqiang Wang Qiusheng Lan Shuiqin Chen Zhanwang Huang Jingyuan Zhang Duanqing Tian Yuntan Qiu Diankui Cai Jiangyun Peng Daning Lu Xiaoqing Yuan Xianzhu Yang dong yin Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation Guangdong-Hong Kong Joint Laboratory for RNA MedicineSun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China Medical Research Center Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China Hefei Institutes of Physical Science Chinese Academy of SciencesHefei 230031China Department of Gastrointestinal Surgery Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China Department of Hepatobiliary Surgery Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China School of Biomedical Sciences and Engineering South China University of TechnologyGuangzhou International CampusGuangzhou 511442China

Transcriptional dysregulation of genes is a hallmark of tumors and can serve as targets for cancer drug ***,it is extremely challenging to develop small-molecule inhibitors to target abnormally expressed transcription factors(TFs)except for the nuclear receptor family of *** is known about the interaction between TFs and transcription cofactors in gastroesophageal adenocarcinoma(GEA)or the therapeutic effects of targeting TF and transcription cofactor *** this study,we found that ETS homologous factor(EHF)expression is promoted by a core transcriptional regulatory circuitry(CRC),specifically ELF3-KLF5-GATA6,and interference with its expression suppressed the malignant biological behavior of GEA ***,we identified Ajuba LIM protein(AJUBA)as a new coactivator of EHF that cooperatively orchestrates transcriptional network activity in ***,we identified KRAS signaling as a common pathway downstream of EHF and ***,dual targeting of EHF and AJUBA by lipid nanoparticles cooperatively attenuated the malignant biological behaviors of GEA in vitro and in *** conclusion,EHF is upregulated by the CRC and promotes GEA malignancy by interacting with AJUBA through the KRAS *** of both EHF and its coactivator AJUBA through lipid nanoparticles is a novel potential therapeutic strategy.

关键词： EHF AJUBA KRAS pathway Enhancer Core transcriptional regulatory circuitry Gastroesophageal adenocarcinoma Gastric adenocarcinoma Esophageal adenocarcinoma Transcription factor Coactivator Lipid nanoparticles

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Dynamic prediction of landslide life expectancy using ensemble system incorporating classical prediction models and machine learning

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Geoscience Frontiers 2024年第2期15卷 202-219页

作者： Lei-Lei Liu Hao-dong yin Ting Xiao Lei Huang Yung-Ming Cheng Key Laboratory of Metallogenic Prediction of Nonferrous Metals and Geological Environment Monitoring Ministry of EducationSchool of Geosciences and Info-PhysicsCentral South UniversityChangsha 410083China College of Civil Engineering and Architecture Wenzhou UniversityWenzhou 325035China Key Laboratory of Engineering and Technology for Soft Soil Foundation and Tideland Reclamation of Zhejiang Province Wenzhou 325035China Wenzhou Key Laboratory of Traffic Piezoelectric Engineering Technology Wenzhou 325035China Zhejiang International Science and Technology Cooperation Base of Ultra-soft Soil Engineering and Smart Monitoring Wenzhou 325035China School of Civil Engineering Qingdao University of TechnologyQingdao 266033China

With the development of landslide monitoring system,many attempts have been made to predict landslide failure-time utilizing monitoring data of *** models(e.g.,Verhulst,GM(1,1),and Saito models)that consider the characteristics of landslide displacement to determine the failuretime have been investigated *** practice,monitoring is continuously implemented with monitoring data-set updated,meaning that the predicted landslide life expectancy(i.e.,the lag between the predicted failure-time and time node at each instant of conducting the prediction)should be re-evaluated with *** manner is termed“dynamic prediction”.However,the performances of the classical models have not been discussed in the context of the dynamic prediction *** this study,such performances are investigated firstly,and disadvantages of the classical models are then reported,incorporating the monitoring data from four real ***,a more qualified ensemble model is proposed,where the individual classical models are integrated by machine learning(ML)-based *** evaluate the quality of the models under the dynamic prediction,a novel indicator termed“discredit index(b)”is proposed,and a higher value of b indicates lower prediction *** is found that Verhulst and Saito models would produce predicted results with significantly higher b,while GM(1,1)model would indicate results with the highest mean absolute ***,the ensemble models are found to be more accurate and qualified than the classical ***,the performance of decision tree regression-based ensemble model is the best among the various ML-based ensemble models.

关键词： Dynamic prediction Landslide life expectancy Machine learning Ensemble system

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The effect of fasting plasma glucose on in-hospital mortality after acute myocardial infarction in patients with and without diabetes:findings from a prospective,nationwide,and multicenter registry

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Journal of Geriatric Cardiology 2024年第5期21卷 523-533页

作者： Rui FU ying-Xuan ZHU Kong-Yong CUI Jin-Gang YANG Hai-Yan XU dong yin Wei-Hua SONG Hong-Jian WANG Cheng-Gang ZHU Lei FENG Wei WU Kai-HongCHEN Yan-Yan ZHAO Ye LU Ke-Fei DOU Yue-Jin YANG on behalf of the CAMI Registry Investigators Cardiometabolic Medicine Center Fuwai HospitalNational Center for Cardiovascular DiseasesState Key Laboratory of Cardiovascular DiseaseNational Clinical Research Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Medical Research&Biometrics Center Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Coronary Heart Disease Center Fuwai HospitalNational Center for Cardiovascular DiseasesState Key Laboratory of Cardiovascular DiseaseNational Clinical Research Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Cardiology Guangzhou Traditional Chinese Medical College First Affiliated HospitalGuangdong ProvinceChina Department of Cardiology Longyan Hospital First HospitalFujian ProvinceChina 不详

OBJECTIVES To evaluate the predictive value of fasting plasma glucose(FPG)for in-hospital mortality in patients with acute myocardial infarction(AMI)with different glucose metabolism *** We selected 5,308 participants with AMI from the prospective,nationwide,multicenter CAMI registry,of which 2,081 were diabetic and 3,227 were *** were divided into high FPG and low FPG groups according to the optim-al cutoff values of FPG to predict in-hospital mortality for diabetic and nondiabetic cohorts,*** primary endpoint was in-hospital *** Overall,94 diabetic patients(4.5%)and 131 nondiabetic patients(4.1%)died during hospitalization,and the optimal FPG thresholds for predicting in-hospital death of the two cohorts were 13.2 mmol/L and 6.4 mmol/L,*** with individuals who had low FPG,those with high FPG were significantly associated with higher in-hospital mortality in diabet-ic cohort(10.1%vs.2.8%;odds ratio[OR]=3.862,95%confidence interval[CI]:2.542-5.869)and nondiabetic cohort(7.4%vs.1.7%;HR=4.542,95%CI:3.041-6.782).After adjusting the potential confounders,this significant association was not ***-more,FPG as a continuous variable was positively associated with in-hospital mortality in single-variable and multivariable models regardless of diabetic *** FPG to the original model showed a significant improvement in C-statistic and net reclassification in diabetic and nondiabetic *** This large-scale registry indicated that there is a strong positive association between FPG and in-hospital mor-tality in AMI patients with and without *** might be useful to stratify patients with AMI.

关键词： patients fasting infarction

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饱和吸收体恢复时间对正交偏振耗散孤子的影响

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中国光学（中英文） 2024年第3期17卷 714-723页

作者：何晓颖张川张银东饶岚北京邮电大学电子工程学院天地互联与融合北京市重点实验室北京100876

偏振在脉冲锁模时,对其塑形和稳定起着至关重要的作用。本研究开发了一种用于产生正交偏振耗散孤子的被动锁模石墨烯光纤激光器的正交偏振数值模拟。重点是分析由偏振依赖的石墨烯微光纤饱和吸收体引起的净正常色散双折射腔对正交偏振... 详细信息

偏振在脉冲锁模时,对其塑形和稳定起着至关重要的作用。本研究开发了一种用于产生正交偏振耗散孤子的被动锁模石墨烯光纤激光器的正交偏振数值模拟。重点是分析由偏振依赖的石墨烯微光纤饱和吸收体引起的净正常色散双折射腔对正交偏振孤子的影响。研究结果表明,这种饱和吸收体的恢复时间显著影响正交偏振耗散脉冲的特性,如能量、脉宽、时间带宽乘积和啁啾。结果显示,其恢复时间为120飞秒时最佳,产生两个具有大啁啾的正交偏振的窄耗散孤子脉冲,分别约为7.47 ps和8.06 ps。这对于开发紧凑、高功率、偏振耗散孤子光纤激光系统具有重要意义。

关键词：正交偏振光被动锁模净正常色散腔恢复时间

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科技企业进驻促进共同富裕了吗?——来自工商企业注册的证据

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求是学刊 2024年第2期51卷 69-80页

作者：董康银刘洋王辉对外经济贸易大学国际经济贸易学院北京100029 湖南大学经济与贸易学院长沙410006

国之称富者,在乎丰民。党的十八大以来,逐步实现全体人民共同富裕被摆在了更加重要的位置。在扎实推动共同富裕的历史新阶段,探索实现共同富裕的新途径,推动改革发展成果更多更公平惠及全体人民,以实现全体人民共同富裕具有重大意义。... 详细信息

国之称富者,在乎丰民。党的十八大以来,逐步实现全体人民共同富裕被摆在了更加重要的位置。在扎实推动共同富裕的历史新阶段,探索实现共同富裕的新途径,推动改革发展成果更多更公平惠及全体人民,以实现全体人民共同富裕具有重大意义。在此背景下,本文利用2006—2020年全国295个城市数据,构建了共同富裕指标体系并进行了测算,发现我国全体人民共同富裕水平不断提升。在此基础上,本文利用全国工商注册企业数据库,进一步探究了科技企业进驻对共同富裕的影响,并得出以下结论:科技企业进驻能够显著促进共同富裕,这一结论在一系列稳健性检验仍旧成立;异质性分析表明,科技企业进驻对东部、中部地区和高共同富裕地区效果更显著;机制分析表明,科技企业进驻通过促进产业结构升级和科技创新等途径对共同富裕产生影响。本文的研究为深入了解科技企业进驻与共同富裕之间的内在关联提供了经验证据,对深化共同富裕目标的实现提供了有力的理论支持和实践指导。

关键词：共同富裕科技企业进驻创新发展

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北京西山岩溶地下水化学特征及成因分析

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环境科学 2024年第2期45卷 802-812页

作者：郭高轩代垠东许亮朱琳欧志亮戚琦辛宝东北京市地质环境监测所北京100195 城市地下水安全防控技术创新基地北京100195 首都师范大学水资源安全北京实验室北京100048

岩溶地下水是北京市重要的供水水源,西山岩溶水系统地处北京西部上游地区,绝大多数属于生态涵养区,区内分布有多个集中供水水源地,在城市供水安全和生态环境保护中发挥着难以替代的作用.以西山岩溶水系统为研究对象,开展系统地下水水化... 详细信息

岩溶地下水是北京市重要的供水水源,西山岩溶水系统地处北京西部上游地区,绝大多数属于生态涵养区,区内分布有多个集中供水水源地,在城市供水安全和生态环境保护中发挥着难以替代的作用.以西山岩溶水系统为研究对象,开展系统地下水水化学组分调查,综合运用统计分析法、离子比例法以及主成分分析法(PCA)等方法,对研究区120件岩溶地下水样品进行了分析研究,探讨了地下水水化学空间分布特征及其形成机制.结果表明:①西山系统地下水水质整体状况较好,属中性、低盐度的优质淡水,84.17%水样属于硬水,地下水化学类型以HCO_(3)-Ca·Mg为主;②地下水化学组分主要受到水-岩石相互作用控制,岩石风化源类型由蒸发岩、硅酸盐和碳酸盐共同控制,以碳酸盐风化为主要控制因素.③主成分分析结果表明,系统地下水化学形成的34.41%归因于碳酸盐岩的溶解,27.33%来源于岩盐、蒸发岩溶解,11.76%来自于含水层沉积物的溶解,10.30%来自于人类活动生活污水的排放.由补给区到径流区再到排泄区,地下水TH、TDS逐渐升高.采煤活动和人类活动是引起山前地带地下水劣变和水化学类型多变的主要因素.未来应进一步加强环境治理,做好点源和面源污染治理,对重点部位持续监测,为生态环境保护提供科学支撑.

关键词：北京西山岩溶水系统水化学特征主成分分析(PAC) 成因分析

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