检索结果-南通市图书馆

Multilevel analysis of the central-peripheral-target organ pathway:contributing to recovery after peripheral nerve injury

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2807-2822页

作者： Xizi Song Ruixin Li Xiaolei Chu Qi Li Ruihua Li Qingwen Li Kai-Yu Tong Xiaosong Gu dong ming Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjinChina Haihe Laboratory of Brain-Machine Interface and Human-Machine Fusion TianjinChina Department of Rehabilitation Tianjin University Tianjin HospitalTianjinChina Department of Hand Microsurgery Tianjin University Tianjin HospitalTianjinChina School of Exercise and Health Tianjin University of SportTianjinChina Department of Biomedical Engineering the Chinese University of Hong KongHong Kong Special Administrative RegionChina

Peripheral nerve injury is a common neurological condition that often leads to severe functional limitations and *** on the pathogenesis of peripheral nerve injury has focused on pathological changes at individual injury sites,neglecting multilevel pathological analysis of the overall nervous system and target *** has led to restrictions on current therapeutic *** this paper,we first summarize the potential mechanisms of peripheral nerve injury from a holistic perspective,covering the central nervous system,peripheral nervous system,and target *** peripheral nerve injury,the cortical plasticity of the brain is altered due to damage to and regeneration of peripheral nerves;changes such as neuronal apoptosis and axonal demyelination occur in the spinal *** nerve will undergo axonal regeneration,activation of Schwann cells,inflammatory response,and vascular system regeneration at the injury *** damage to target organs can occur,including skeletal muscle atrophy and sensory receptor *** then provide a brief review of the research advances in therapeutic approaches to peripheral nerve *** main current treatments are conducted passively and include physical factor rehabilitation,pharmacological treatments,cell-based therapies,and physical ***,most treatments only partially address the problem and cannot complete the systematic recovery of the entire central nervous system-peripheral nervous system-target organ ***,we should further explore multilevel treatment options that produce effective,long-lasting results,perhaps requiring a combination of passive(traditional)and active(novel)treatment methods to stimulate rehabilitation at the central-peripheral-target organ levels to achieve better functional recovery.

关键词： central nervous system central peripheral target organ multilevel pathological analysis nerve regeneration peripheral nerve injury peripheral nervous system target organs therapeutic approach

双进气道结构下带凹腔补燃室燃烧特性数值研究

在线全文

学校读者我要写书评

暂无评论

大连理工大学学报 2025年第1期65卷 38-47页

作者：王彦红姚弘悦东明东北电力大学能源与动力工程学院吉林吉林132012 大连理工大学能源与动力学院辽宁大连116024

针对导弹应用固体冲压发动机补燃室的掺混燃烧问题,通过一次燃气的气相燃烧模型和硼燃料的KING燃烧模型,探究了双侧90°和双侧180°进气条件下带凹腔补燃室(后倾角范围为90°~150°)的温度场和流场分布情况.阐述了凹腔旋流效应及其对燃... 详细信息

针对导弹应用固体冲压发动机补燃室的掺混燃烧问题,通过一次燃气的气相燃烧模型和硼燃料的KING燃烧模型,探究了双侧90°和双侧180°进气条件下带凹腔补燃室(后倾角范围为90°~150°)的温度场和流场分布情况.阐述了凹腔旋流效应及其对燃烧过程和燃烧产物的影响,进行了燃烧性能量化分析.数值结果表明:双侧180°进气条件下凹腔增大了燃料和空气的掺混空间,凹腔截面出现4个大对冲旋涡,掺混更加均匀,有利于燃烧组织,有效燃烧空间更大,补燃室出口总燃烧效率达到85%.双侧90°进气条件下凹腔截面形成逆时针单向旋涡,燃烧集中在狭小空间,对燃烧过程不利,补燃室出口总燃烧效率仅为55%.凹腔后倾角由90°提高到120°时,燃料和空气的掺混空间增大,促进了燃烧过程.凹腔后倾角继续提高到150°,凹腔空间增大改善燃烧的作用微弱.

关键词：双进气道结构凹腔补燃室硼颗粒燃烧过程

Turbulent Agglomeration of Microparticles in a Cylinder Wake Flow Using LES-DEM:Focusing on the Effect of the Reynolds Number

在线全文

学校读者我要写书评

暂无评论

Journal of Thermal Science 2025年第1期 34-49页

作者： WANG Shuang MU Lin LI Xue XIE Jun dong ming School of Energy and Power Engineering Dalian University of Technology School of Optical Information and Energy Engineering Wuhan Institute of Technology School of Energy and Environment Shenyang Aerospace University

Turbulent agglomeration is viewed as a promising technology for enhancing fine particle removal *** better understand particle transport,agglomeration behaviors,and fluid-particle interactions,we numerically explored these phenomena under cylindrical vortex wake influence using a coupled large eddy simulation and discrete element method（LES-DEM） *** validity of the LES approach was verified by comparison with available direct numerical simulation（DNS） *** adopted the Johnson-Kendall-Roberts（JKR） contact model for particle-particle *** particle dispersion and agglomeration characteristics of particles with different diameters（dp=2-20 μm） in the laminar and transition of shear layer（TrSL） flow regimes were *** particles were concentrated at the vortex centers,while larger particles accumulated around the *** agglomeration efficiency exhibited an M-shaped profile spanwise（y-direction）.With increasing Reynolds number,the agglomeration efficiency and turbulence intensity *** particle agglomeration efficiency peaks at a certain Reynolds ***,at higher Reynolds numbers,reducing the residence time of particles in the flow field decreases the agglomeration efficiency.

关键词：

Scattering of Tollmien-Schlichting waves by localized roughness in transonic boundary layers

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2020年第7期41卷 1105-1124页

作者： ming dong Department of Mechanics Tianjin UniversityTianjin 300072China Laboratory for High-Speed Aerodynamics Tianjin UniversityTianjin 300072China

The laminar-turbulent transition in boundary-layer flows is often affected by wall imperfections, because the latter may interact with either the freestream perturbations or the oncoming boundary-layer instability modes, leading to a modification of the accumulation of the normal modes. The present paper particularly focuses on the latter mechanism in a transonic boundary layer, namely, the effect of a two-dimensional(2 D) roughness element on the oncoming Tollmien-Schlichting(T-S) modes when they propagate through the region of the rapid mean-flow distortion induced by the roughness. The wave scattering is analyzed by adapting the local scattering theory developed for subsonic boundary layers(WU, X. S. and dong, M. A local scattering theory for the effects of isolated roughness on boundary-layer instability and transition: transmission coefficient as an eigenvalue. Journal of Fluid Mechanics, 794, 68–108(2006)) to the transonic regime, and a transmission coefficient is introduced to characterize the effect of the roughness. In the sub-transonic regime, in which the Mach number is close to, but less than, 1, the scattering system reduces to an eigenvalue problem with the transmission coefficient being the eigenvalue;while in the super-transonic regime, in which the Mach number is slightly greater than 1, the scattering system becomes a high-dimensional group of linear equations with the transmission coefficient being solved afterward. In the largeReynolds-number asymptotic theory, the K′arm′an-Guderley parameter is introduced to quantify the effect of the Mach number. A systematical parametric study is carried out,and the dependence of the transmission coefficient on the roughness shape, the frequency of the oncoming mode, and the K′arm′an-Guderley parameter is provided.

关键词： boundary layer scattering instability Tollmien-Schlichting(T-S)wave triple deck

Interpretation of gas-film cooling against aero-thermal heating for high-speed vehicles

在线全文

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2016年第12期37卷 1615-1630页

作者： ming dong Department of Mechanics Tianjin UniversityTianjin 300072China Tianjin Key Laboratory of Modern Engineering Mechanics Tianjin 300072China

The possible application of the film-cooling technique against aero-thermal heating for surfaces of high-speed flying vehicles is discussed. The technique has been widely used in the heat protection of gas turbine blades. It is shown in this paper that, by applying this technique to high-speed flying vehicles, the working principle is fundamentally different. Numerical simulations for two model problems axe performed to support the argument. Besides the heat protection, the appreciable drag reduction is found to be another favorable effect. For the second model problem, i.e., the gas cooling for an optical window on a sphere cone, the hydrodynamic instability of the film is studied by the linear stability analysis to observe possible occurrence of laminar-turbulent transition.

关键词： film cooling aero-thermal heating numerical simulation laminar-turbulenttransition linear stability analysis

Near-wall behaviors of oblique-shock-wave/turbulent-boundary-layer interactions

在线全文

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2017年第10期38卷 1357-1376页

作者： mingsheng YE ming dong Department of Mechanics Tianjin University Tianjin Key Laboratory of Modern Engineering Mechanics

A direct numerical simulation （DNS） on an oblique shock wave with an incident angle of 33.2° impinging on a Mach 2.25 supersonic turbulent boundary layer is performed. The numerical results are confirmed to be of high accuracy by comparison with the reference data. Particular efforts have been made on the investigation of the near-wall behaviors in the interaction region, where the pressure gradient is so significant that a certain separation zone emerges. It is found that, the traditional linear and loga- rithmic laws, which describe the mean-velocity profiles in the viscous and meso sublayers, respectively, cease to be valid in the neighborhood of the interaction region, and two new laws of the wall are proposed by elevating the pressure gradient to the leading order. The new laws are inspired by the analysis on the incompressible separation flows, while the compressibility is additionally taken into account. It is verified by the DNS results that the new laws are adequate to reproduce the mean-velocity profiles both inside and outside the interaction region. Moreover, the normalization adopted in the new laws is able to regularize the Reynolds stress into an almost universal distribution even with a salient adverse pressure gradient （APG）.

关键词： shock wave turbulent boundary layer direct numerical simulation (DNS),adverse pressure gradient (APG) separation

Scattering of Tollmien-Schlichting waves as they pass over forward-/backward-facing steps

在线全文

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2018年第10期39卷 1411-1424页

作者： ming dong Anyong ZHANG Department of Mechanics Tianjin UniversityTianjin 300072China Tianjin Key Laboratory of Modern Engineering Mechanics Tianjin 300072China

Forward-/backward-facing steps in boundary-layer flows are often seen in engineering applications, and they have potential impacts on laminar-turbulent transition through scattering of the oncoming instability modes(e.g., Tollmien-Schlichting(T-S) waves). This issue is studied in the present paper by applying a local scattering framework, which is a rather generic mathematical framework on describing the mode scattering process. In this framework, a high-Reynolds-number triple-deck formalism is employed, and a transmission coefficient, defined as the ratio of the asymptotic amplitude of the instability mode downstream of the step to that upstream, is introduced. Through the systematical study, it has been found that both the forward-and backward-facing steps have a destabilizing effect on the oncoming T-S waves in subsonic boundary layers, this effect increases with the height of the step and/or the frequency of the T-S wave, and a backward-facing step(BFS) always has a greater impact than a forward-facing step(FFS). These facts agree with most of the previous ***, one numerical study(WORNER, A., RIST, U., and WAGNER, S. Humps/steps influence on stability characteristics of two-dimensional laminar boundary layer. AIAA Journal, 41, 192–197(2003)), which was based on an ad-hoc configuration, showed an opposite impact of an FFS. Through the investigation on the specific configuration, it is revealed that the wrong conclusion was drawn by misinterpreting the numerical results.

关键词： boundary layer scattering instability Tollmien-Schlichting(T-S) wave triple deck

A Class of Finite-Dimensional Representations of U_q(sl_2)

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2013年第9期29卷 1703-1712页

作者： dong ming CHENG dong SU Department of Mathematics and Applied Mathematics He'nan University of Science and Technology

In order to study a class of finite-dimensional representations of Uq（sl2）, we deal with the quotient algebra Uq （m, n, b） of quantum group Uq（sl2） with relations Kr=1, Emr=b, Fnr=0 in this paper, where q is a root of unity. The algebra Uq（m, n, b） is decomposed into a direct sum of indecomposable （left） ideals. The structures of indecomposable projective representations and their blocks are determined.

关键词： Quantum group representation root of unity

Boundary-layer disturbances subjected to free-stream turbulence and simulation on bypass transition

在线全文

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2016年第8期37卷 967-986页

作者： Hong QIN ming dong Department of Mechanics Tianjin University Tianjin 300072 China Tianjin Key Laboratory of Modern Engineering Mechanics Tianjin 300072 China

The phenomena associated with the entrainment of free-stream turbulence （FST） into boundary-layer flows are relevant for a number of subjects. It has been be- lieved that the continuous spectra of the Orr-Sommerfeld （O-S）/Squire equations describe the entrainment process, and thus they are used to specify the inlet condition in simulation of bypass transition. However, dong and Wu （dong, M. and Wu, X. On continuous spectra of the Orr-Sommerfeld/Squire equations and entrainment of free-stream vortical disturbances. Journal of Fluid Mechanics, 732, 616-659 （2013）） pointed out that continuous spectra exhibit several non-physical features due to neglecting the non-parallelism. They further proposed a large-Reynolds-number asymptotic approach, and showed that the non-parallelism is a leading-order effect even for the short-wavelength disturbance, for which the response concentrates in the edge layer. In this paper, the asymptotic solution is verified numerically by studying its evolution in incompressible boundary layers. It is found that the numerical results can be accurately predicted by the asymptotic solution, implying that the latter is adequate for moderate Reynolds numbers. By introducing a series of such solutions as the inflow perturbations, the bypass transition is investigated via the direct numerical simulation （DNS）. The transition processes, including the evolution of streaks, the amplification of secondary-instability modes, and the emergence of turbulent spots, agree with the experimental observations.

关键词： free-stream turbulence (FST) bypass transition boundary layer asymptotic direct numerical simulation (DNS)