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The non-destructive analysis of ancient jade artifacts unearthed from the Liangzhu sites at Yuhang,zhejiang

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Science china.Technological Sciences) 2010年第12期53卷 3404-3419页

作者： GAN FuXi1,3, CAO JingYan2, CHENG HuanSheng3, Gu dongHong1, RUI GuoYao2, FANG XiangMing2, dong JunQing1 & ZHAO HongXia1 1Scientific Archeology Center, shanghai institute of Optics and Fine Mechanics, Chinese Academy of Sciences, shanghai 201800, china.2 Research institute of Cultural Relics and Archeology of zhejiang, hangzhou 310014, china.3 fudan university, shanghai 200433, china 1. Scientific Archeology Center Shanghai Institute of Optics and Fine Mechanics Chinese Academy of Sciences Shanghai 201800 China3. Fudan University Shanghai 200433 China2. Research Institute of Cultural Relics and Archeology of Zhejiang Hangzhou 310014 China

Samples of the jade artifacts unearthed from the Liangzhu sites at Yuhang (Fanshan,Yaoshan, Huiguanshan and Tangshan) of zhejiang province were described. The chemical composition, phase and jade structure of a hundred and more intact samples were analyzed by the non-destructive techniques of PIXE, XRD and laser Raman spectroscopy. Results showed that the minerals of the jade artifacts mostly belonged to tremolite and tremolite-actinolite. Relationship of the civilization development in the Neolithic age and the application of tremolite type mineral in jade artifacts was discussed. The contents of rare and trace elements in tremolite jade artfacts and in mineral samples were measured for the first time. The possible mineral sources of these tremolite type jade artifacts were discussed.

关键词： Liangzhu culture non-destructive analysis ancient jade artifacts essence and source

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Observation of transition from superfluorescence to polariton condensation in CsPbBr3 quantum dots film

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Light(Science & Applications) 2024年第2期13卷 316-324页

作者： Danqun Mao Linqi Chen zheng Sun Min Zhang zhe-Yu Shi Yongsheng Hu Long Zhang Jian Wu Hongxing dong Wei Xie Hongxing Xu State Key Laboratory of Precision Spectroscopy East China Normal UniversityShanghai 200241China Key Laboratory of Materials for High-Power Laser Shanghai Institute of Optics and Fine MechanicsChinese Academy of Sciences201800 ShanghaiChina Collaborative Innovation Center of Extreme Optics Shanxi UniversityTaiyuanShanxi 030006China Chongqing Key Laboratory of Precision Optics Chongqing Institute of East China Normal UniversityChongqing 401121China CAS Center for Excellence in Ultraintense Laser Science Shanghai 201800China School of Physics and Technology Center for Nanoscience and NanotechnologyWuhan UniversityWuhan 430072China

The superfluorescence effect has received extensive attention due to the many-body physics of quantum correlation in dipole gas and the optical applications of ultrafast bright radiation field based on the cooperative quantum ***,we demonstrate not only to observe the superfluorescence effect but also to control the cooperative state of the excitons ensemble by externally applying a regulatory dimension of coupling light fields.A new quasi-particle called cooperative exciton-polariton is revealed in a light-matter hybrid structure of a perovskite quantum dot thin film spin-coated on a Distributed Bragg *** the nonlinear threshold,polaritonic condensation occurs at a nonzero momentum state on the lower polariton branch owning to the vital role of the synchronized *** phase transition from superfluorescence to polariton condensation exhibits typical signatures of a decrease of the linewidth,an increase of the macroscopic coherence as well as an accelerated radiation decay *** findings are promising for opening new potential applications for super-brightness and unconventional coherent light sources and could enable the exploitation of cooperative effects for quantum optics.

关键词： quantum condensation polar

TGF-β1-promoted epithelial-to-mesenchymal transformation and cell adhesion contribute to TGF-β1-enhanced cell migration in SMMC-7721 cells

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Cell Research 2003年第5期13卷 343-350页

作者： zheN XU, MIN XIONG SHEN, dong ZHU MA, LI YING WANG, XI LIANG ZHA Key Laboratory of Glycoconjugate Research, Ministry of Public Health, Department of Biochemistry and Molecular Biology, shanghai Medical College, fudan university, shanghai 200032, china.2 Medical School, Huzhou Teacher’s College, Huzhou zhejiang 313000, china 1Key Laboratory of Glycoconjugate Research Ministry of Public Health Department of Biochemistry and Molecular Biology Shanghai Medical College Fudan University Shanghai 200032 China. Email: xlzha@*** 2Medical School Huzhou Teacher s College Huzhou Zhejiang 313000 China 1Key Laboratory of Glycoconjugate Research Ministry of Public Health Department of Biochemistry and Molecular Biology Shanghai Medical College Fudan University Shanghai 200032 China. Email: xlzha@*** 1Key Laboratory of Glycoconjugate Research Ministry of Public Health Department of Biochemistry and Molecular Biology Shanghai Medical College Fudan University Shanghai 200032 China. Email: xlzha@*** 1Key Laboratory of Glycoconjugate Research Ministry of Public Health Department of Biochemistry and Molecular Biology Shanghai Medical College Fudan University Shanghai 200032 China. Email: xlzha@***

Transforming growth factor-b 1 (TGF-β1), a multi-function polypeptide, is a double-edged sword in cancer. For some tumor cells, TGF-β1 is a potent growth inhibitor and apoptosis inducer. More commonly, TGF-β1 loses its growth-inhibitory and apoptosis-inducing effects, but stimulates the metastatic capacity of tumor cells. It is currently little known about TGF-β1-promoted cell migration in hepatocellular carcinoma (HCC) cells, let alone its mechanism. In this study, we found that TGF-β1 lost its tumor-suppressive effects, but significantly stimulated cell migration in SMMC-7721 human HCC cells. By FACS and Western blot analysis, we observed that TGF-β1 enhanced the expression of α5β1 integrin obviously, and subsequently stimulated cell adhesion onto fibronectin (Fn). Furthermore, we observed that TGF-β1 could also promote SMMC-7721 cells adhesion onto laminin (Ln). Our data also provided evidences that TGF-β1 induced epithelial-to-mesenchymal transformation (EMT) in SMMC-7721 cells. First, SMM

关键词： TGF-β1 cell migration epitheIial-to-mesenchymal transformation α5β1 integrin.

CPT: a pre-trained unbalanced transformer for both Chinese language understanding and generation

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Science china.Information Sciences) 2024年第5期67卷 43-55页

作者： Yunfan SHAO Zhichao GENG Yitao LIU Junqi DAI Hang YAN Fei YANG zhe LI Hujun BAO Xipeng QIU School of Computer Science Fudan University shanghai Key Laboratory of Intelligent Information Processing Fudan University zhejiang Lab

In this paper, we take the advantage of previous pre-trained models(PTMs) and propose a novel Chinese pre-trained unbalanced transformer(CPT). Different from previous Chinese PTMs, CPT is designed to utilize the shared knowledge between natural language understanding(NLU) and natural language generation(NLG) to boost the performance. CPT consists of three parts: a shared encoder, an understanding decoder, and a generation decoder. Two specific decoders with a shared encoder are pretrained with masked language modeling(MLM) and denoising auto-encoding(DAE) tasks, *** the partially shared architecture and multi-task pre-training, CPT can(1) learn specific knowledge of both NLU or NLG tasks with two decoders and(2) be fine-tuned flexibly that fully exploits the potential of the model. Moreover, the unbalanced transformer saves the computational and storage cost, which makes CPT competitive and greatly accelerates the inference of text generation. Experimental results on a wide range of Chinese NLU and NLG tasks show the effectiveness of CPT.

关键词： pre-trained model transformer language model generation unified model

Dimensionality-driven metal to Mott insulator transition in two-dimensional 1T-TaSe2

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National Science Review 2024年第3期11卷 108-118页

作者： Ning Tian zhe Huang Bo Gyu Jang Shuaifei Guo Ya-Jun Yan Jingjing Gao Yijun Yu Jinwoong Hwang Cenyao Tang Meixiao Wang Xuan Luo Yu Ping Sun Zhongkai Liu dong-Lai Feng Xianhui Chen Sung-Kwan Mo Minjae Kim Young-Woo Son Dawei Shen Wei Ruan Yuanbo Zhang State Key Laboratory of Surface Physics New Cornerstone Science Laboratory and Department of PhysicsFudan University shanghai Qi Zhi institute shanghai Research Center for Quantum Sciences institute for Nanoelectronic Devices and Quantum Computing Fudan University Zhangjiang fudan International Innovation Center Fudan University State Key Laboratory of Functional Materials for Informatics Shanghai Institute of Microsystem and Information Technology(SIMIT)Chinese Academy of Sciences School of Physical Science and Technology ShanghaiTech University Korea institute for Advanced Study School of Emerging Technology and Department of Physics University of Science and Technology of China Advanced Light Source Lawrence Berkeley National Laboratory shanghaiTech Laboratory for Topological Physics Key Laboratory of Materials Physics Institute of Solid State Physics Hefei Institutes of Physical ScienceChinese Academy of Sciences High Magnetic Field Laboratory Hefei Institutes of Physical Science Chinese Academy of Sciences Collaborative Innovation Centre of Advanced Microstructures Nanjing University Department of Physics University of Science and Technology of China and Key Laboratory of Strongly Coupled Quantum Matter Physics Chinese Academy of Sciences National Synchrotron Radiation Laboratory University of Science and Technology of China

Two-dimensional materials represent a major frontier for research into exotic many-body quantum phenomena. In the extreme two-dimensional limit, electron-electron interaction often dominates over other electronic energy scales, leading to strongly correlated effects such as quantum spin liquid and unconventional *** dominance is conventionally attributed to the lack of electron screening in the third dimension. Here, we discover an intriguing metal to Mott insulator transition in 1T-TaSe2that defies conventional wisdom. Specifically, we find that dimensionality crossover, instead of reduced screening, drives the transition in atomically thin 1T-TaSe2. A dispersive band crossing the Fermi level is found to be responsible for the bulk metallicity in the material. Reducing the dimensionality,however, effectively quenches the kinetic energy of these initially itinerant electrons, and drives the material into a Mott insulating *** dimensionality-driven metal to Mott insulator transition resolves the long-standing dichotomy between metallic bulk and insulating surface of 1T-TaSe2. Our work further reveals a new pathway for modulating two-dimensional materials that enables exploring strongly correlated systems across uncharted parameter space.

关键词： two-dimensional materials 1T-TaSe2 dimensionality crossover metal to Mott insulator transition

A new formula for estimation fetal of weights less than 2500g by using ultrasound scanning

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A new formula for estimation fetal of weights less than 2500...

Quantitative evaluation of contrast-enhanced ultrasonography in the diagnosis of chronic ischemic renal disease in a dog model

第二届长三角超声医学论坛暨2009年浙江省超声医学学术年会

作者： Department of Ultrasound,The First Maternity and Infant Health Hospital,shanghai 200040,china.Department of Electronic Engineering,fudan university,shanghai 200032,china.Center for Disease Control and Prevention,shanghai 201204,china.Department of Ultrasound,Cancer Hospital,fudan university,shanghai 200032,china.Ping CHEN Jin-hua YU Yuan-yuan WANG Guo-dong TIAN Cai CHANG

Objective To develop a new formula to estimate fetal weight in fetuses of less than 2500g. Methods A new formula was developed from 220 low weight(≤2500g) fetuses,singleton fetuses, examined within 3 days before birth *** regression analysis was used to develop the new formula with BPD HC AC and FL *** another 94 fetuses whose birth weight were lower than 2500g the new

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Quantitative evaluation of contrast-enhanced ultrasonography...

Multifunctional RGD coated a single-atom iron nanozyme:A highly selective approach to inducing ferroptosis and enhancing immunotherapy for pancreatic cancer

第二届长三角超声医学论坛暨2009年浙江省超声医学学术年会

作者： Department of Ultrasound,Huashan Hospital,fudan university,shanghai 200040,china.Yi dong Department of Diagnostic Ultrasound,Zhongshan Hospital,fudan university,shanghai 200032,china.Wen-ping WANG Hong DING Jia-ying CAO Pei-li FAN Xi-yuan LIN

Objective Chronic ischemic renal disease(CIRD) is very common in clinical medicine,which is very complicated in its pathological *** of perfusion is an early event in the course of renal dysfunction and usually preced...

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Nano Research 2024年第6期17卷 5469-5478页

作者： Haoqi Pan Xu Chen Mingming Xiao He Xu Jiansheng Guo Zhiyi Lu dong Cen Xianjun Yu Si Shi Department of Pancreatic Surgery Fudan University Shanghai Cancer CenterShanghai 200032China Department of Oncology Shanghai Medical CollegeFudan UniversityShanghai 200032China shanghai Pancreatic Cancer institute Shanghai 200032China Pancreatic Cancer institute Fudan UniversityShanghai 200032China Key Laboratory of Advanced Fuel Cells and Electrolyzers Technology of zhejiang Province Qianwan Institute of CNITECHNingbo Institute of Materials Technology and EngineeringChinese Academy of SciencesNingbo 315201China Department of Pathology of Sir Run Run Shaw Hospital Zhejiang University School of MedicineHangzhou 310016China Key Laboratory of Laparoscopic Technology of zhejiang Province Department of General SurgerySir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China

Nanozyme is a new promising approach to cancer therapy for its ability to induce ferroptosis by activating H_(2)O_(2)via a traditional radical pathway and enhance cancer ***,short half-life period of hydroxyl radical(·OH)results in unsatisfied ***,we synthesized a single-atom iron nanozyme(Fe-SAzyme),which can activate H_(2)O_(2)via a non-radical pathway to generate Fe-based reactive oxygen species(ROS)(O=FeO_(3)=O)for promoting the ferroptosis of pancreatic cancer *** Fe-SAzyme could be specifically phagocytosed by pancreatic cancer cells,increasing ROS levels and inhibiting glutathione(GSH)synthesis,which activates *** magnetic resonance imaging(MRI)showed decreased T2 signal after intravenous injection of RGD@Fe-AC(AC=activated carbon).Moreover,RGD@Fe-AC promoted dendritic cell(DC)maturation,overcame Treg-mediated immunosuppression,activated T cells to trigger adaptive immune responses,and enhanced the efficacy ofα-PD-L1 *** research demonstrated that RGD@Fe-AC provided a straightforward,easily implemented,and selective approach for pancreatic cancer treatment and immunotherapy.

关键词： single-atom iron nanozyme pancreatic cancer immunotherapy ferroptosis

Influence of sex on outcomes of liver transplantation for hepatocellular carcinoma:a multicenter cohort study in china

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Cancer Biology & Medicine 2024年第4期21卷 347-362页

作者： Jian Chen zhe Yang Fengqiang Gao Zhisheng Zhou Junli Chen Di Lu Kai Wang Meihua Sui zhengxin Wang Wenzhi Guo Guoyue Lyu Haizhi Qi Jinzhen Cai Jiayin Yang Shusen zheng Xiao Xu zhejiang university School of Medicine Hangzhou 310030China institute of Organ Transplantation Zhejiang UniversityHangzhou 310030China Department of Hepatobiliary and Pancreatic Surgery Shulan Hospital of HangzhouHangzhou 310006China National Center for Healthcare Quality Management in Liver Transplant Hangzhou 310003China Department of General Surgery Huashan HospitalFudan UniversityShanghai 200040China Department of Hepatobiliary and Pancreatic Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China Department of Hepatobiliary and Pancreatic Surgery The First Hospital of Jilin UniversityChangchun 130021China Department of Liver Transplantation Second Xiangya HospitalCentral South UniversityChangsha 410008China Department of Organ Transplantation Center The Affiliated Hospital of Qingdao UniversityQingdao 266003China Department of Liver Surgery and Liver Transplantation Center West China HospitalSichuan UniversityChengdu 610044China NHC Key Laboratory of Combined Multi-organ Transplantation Hangzhou 310003China Department of Hepatobiliary and Pancreatic Surgery The First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China

Objective:Sex-specific differences are observed in various liver diseases,but the influence of sex on the outcomes of hepatocellular carcinoma(HCC)after liver transplantation(LT)remains to be *** study is the first Chinese nationwide investigation of the role of sex in post-LT outcomes in patients with ***:Data for recipients with HCC registered in the china.Liver Transplant Registry between January 2015 and December 2020 were *** associations between donor,recipient,or donor-recipient transplant patterns by sex and the post-LT outcomes were studied with propensity score matching(PSM).The survival associated with different sex-based donor-recipient transplant patterns was further ***:Among 3,769 patients enrolled in this study,the 1-,3-,and 5-year overall survival(OS)rates of patients with HCC after LT were 96.1%,86.4%,and 78.5%,respectively,in female recipients,and 95.8%,79.0%,and 70.7%,respectively,in male recipients after PSM(P=0.009).However,the OS was comparable between recipients with female donors and male *** analysis indicated that male recipient sex was a risk factor for post-LT survival(HR=1.381,P=0.046).Among the donor-recipient transplant patterns,the male-male donor-recipient transplant pattern was associated with the poorest post-LT survival(P<0.05).Conclusions:Our findings highlighted that the post-LT outcomes of female recipients were significantly superior to those of male recipients,and the male-male donor-recipient transplant pattern was associated with the poorest post-LT *** from male donors may provide the most benefit to female *** results indicate that sex should be considered as a critical factor in organ allocation.

关键词： Sex liver transplantation hepatocellular carcinoma outcome recipient donor

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