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Genotypic variation in root morphology, cotton subtending leaf physiology and fiber quality against nitrogen

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Journal of Cotton Research 2021年第4期4卷 358-371页

作者： ASIF Iqbal dong qiang WANG Xiangru GUI Huiping ZHANG Hengheng PANG Nianchang ZHANG Xiling SONG Meizhen State Key Laboratory of Cotton Biology Institute of Cotton Research of Chinese Academy of Agricultural SciencesAnyang 455000China Western Agricultural Research Center of Chinese Academy of Agricultural Sciences ChangjiXinjiang 831100China School of Agricultural Sciences Zhengzhou UniversityZhengzhou 450000China

Background:Nitrogen(N)is important for improving various morphological and physiological processes of cotton but their contribution to fiber quality is still ***:The current study aimed to explore the relationship between root morphology,subtending leaf physiology,and fiber quality of contrasting N-efficient cotton genotypes in response to ***:We analyzed the above parameters of CCRI 69(N-efficient)and Xinluzao-30(XLZ-30,N-inefficient)under control(2.5 mmol·L^(-1))and high N(5 mmol·L^(-1))***:The results showed that root morphological traits were increased in CCRI-69 under control conditions than high *** leaf morphology,chlorophyll and carotenoid contents,free amino acids,and soluble proteins were higher under high N as compared with the ***,soluble sugars,fructose,sucrose contents,and sucrose phosphate synthase were higher under control conditions than high N across the growth *** of the N conditions,all morphological and physiological traits of cotton subtending leaf were higher in CCRI-69 than *** for fiber uniformity,fiber quality traits like fiber length,strength,micronaire,and elongation were improved under control conditions than high *** the genotypes,CCRI-69 had significantly higher fiber length,strength,micronaire,and elongation as compared with *** positive correlations were found between root morphology,soluble sugars,sucrose content,and sucrose phosphate synthase activity with fiber quality traits,***:These findings suggest that CCRI-69 performed better in terms of growth and fiber quality under relatively low N condition,which will help to reduce fertilizer use,the cost of production,and environmental pollution.

关键词： Cotton Fiber quality Nitrogen Root morphology Subtending leaf

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Observations on Cardiac Output in Animal Experiments and Clinical Application of Jiuling Bileaflet Mechanical Valve Prosthesis

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Chinese Journal of Biomedical Engineering(English Edition) 2010年第1期19卷 41-46页

作者： LOU Hai-fang dong Ai-qiang The 2nd Affiliated Hospital of Medical College of Zhejiang Unit ersity Hangzhou 310009 China

Objective： To observe the cardiac output （CO） in animals and patients undergone valve replacement with Jiuling bileaflet mechanical valve prosthesis. Methods： 1. Animal experiments： 6 sheep that subjected to mitral replacement with a 2 I-ram-valve prosthesis were measured by open cardiac catheterization intraoperatively. Echocardiographic and open cardiac catheterization under dobutamine stress were performed on 2 sheep survival for 30 months post-operation.2. Patient measurements： CO of 14 cases of aortic valve and 10 cases of mitral valve was measured by open cardiac catheterization,and after 12 months,it was measured by echocardiography. Results： 1. Animal experiments： The mean CO of 6 sheep was 2.5 L/min intraoperatively by catheterization, and that of 2 sheep survival for 30 months post-implant was 3.0 L/min by echocardiography and 2.9 L/min by catheterization, respectively. 2. Patient measurements： The mean cardiac index of 4 patients with 21 mm valve replacement was （2.55 ± 0.27） L/min/m^2by catheterization, and was （2.84 ± 0.13） L/min/m^2 by echocardiography after 12 months. Conclusion： This study demonstrates that cardiac function on animals and patients return to normal activity after undergone the valve replacement, and the newly valve prosthesis shows excellent hemodynamic performance.

关键词： heart valve prosthesis cardiac output (CO) cardiac index hemodynamics

Risk factors for prostatic inflammation extent and infection in benign prostatic hyperplasia

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Asian Journal of Andrology 2006年第5期8卷 621-627页

作者： Fa-Xian Yi qiang Wei Hong Li Xiang Li Ming Shi qiang dong Yu-Ru Yang Department of Urology West China Hospital West China Medical School Sichuan University Chengdu Sichuan 610041 China

Aim： To investigate the risk factors for prostatic inflammation extent and infection in patients with benign prostatic hyperplasia （BPH） so as to manage prostatic inflammation more efficiently. Methods： Sixty patients with BPH undergoing TURP between September 2005 and December 2005 in West China Hospital of Sichuan University were studied. Prostate fluid （PF） was collected for the measurement of secretory IgA （SIgA） and complement 3 （C3）. Prostate tissue were collected for testing bacterial 16S rDNA by real-time PCR, examining SIgA in the tissue and examining the inflammation. The possible clinical and immune risk factors for prostatic inflammation or infection were analyzed by using the logistic regression method. Results： Abnormal white blood cell count in urinalysis, prostatic infection and a high concentration of C3 in PF are the risk factors for prostatic inflammation extent （P = 0.025, 0.034 and 0.035, respectively and odds ratio [OR] = 18.269, 8.284 and 1.508, respectively）. Risk factors for prostatic infection include the C3 concentration and the concentration of SIgA in PF （P = 0.003 and 0.013, respectively, and OR=1.645 and 0.993, respectively）. Conclusion： The present study suggests that prostatic inflammation is associated with urinary tract infection, prostatic infection and the activated complement and that prostatic infection is associated with the activated complement and downregulated mucosal immunity in prostates of the patients with BPH. It is also suggested that individual immune regulation should be considered in the treatment of prostatic inflammation and infection of patients with BPH.

关键词： inflammation infection logistic regression benign prostatic hyperplasia prostate

Fasudil inhibits platelet-derived growth factor-induced human pulmonary artery smooth muscle cell proliferation by up-regulation of p27^kipl via the ERK signal pathway

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Chinese Medical Journal 2011年第19期124卷 3098-3104页

作者： LIU Ai-jun LING Feng WANG dong WANG qiang LU Xiao-dong LIU Ying-long Department of Pediatric Cardiac Surgery Center Fuwai Hospital Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100037 China

Background RhoA/ Rho kinase （ROCK） pathway is involved in pulmonary arterial hypertension （PAH） and pulmonary artery smooth muscle cell （PASMC） proliferation. Inhibition of ROCK has been proposed as a treatment for PAH. But the mechanism of RhoA/ROCK pathway and its downstream signaling in proliferation of human PASMCs is unclear. We investigated the effect of fasudil, a selective ROCK inhibitor, on platelet-derived growth factor （PDGF） induced human PASMC proliferation, and the possible association between RhoA/ROCK and extracellular signal-regulated kinase （ERK）,*** Human PASMCs were cultured with the stimulation of 10 ng/ml PDGF, and different concentrations of fasudil were added before the addition of mitogen. Cell viability and cell cycle were determined with MTT and flow cytometry respectively. ROCK activity, ERK activity and protein expression of proliferating cell nuclear angigen （PCNA） and p27Kip1 were measured by *** By MTT assay, PDGF significantly increased the OD value that represented human PASMC proliferation, and pretreatment with fasudil significantly reversed this effect in a dose-dependent manner. After PDGF stimulation, the percentage of cells in S phase increased dramatically from 15.6% to 24.3%, while the percentage in G0/G1 phase was reduced from 80.6% to 59%. And pretreatment with fasudil reversed the cell cycle effect of PDGF significantly in a dose-dependent manner. PDGF markedly induced ROCK activity and ERK activity with a peak at 15 minutes, which were significantly inhibited by fasudil. In addition, fasudil significantly inhibited PDGF-induced PCNA expression and fasudil also upregulated p27Kip1 expression in human PASMCs, which decreased after PDGF *** RhoA/ROCK is vital for PDFG-induced human PASMC proliferation, and fasudil effectively inhibited PDGF-induced human PASMC proliferation by up-regulation of p27Kip1, which may be associated with inhibition of ERK activity.

关键词： human pulmonary smooth muscle cell proliferation Rho-kinase fasudil extracellular signal-regulated kinase p27^kip1

习近平关于民族工作重要论述的马克思主义政治哲学基础

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民族研究 2020年第6期 18-28,M0002页

作者：董强贵州民族大学民族学与历史学学院贵阳市550025

本文试从马克思主义政治哲学的视角,探析习近平关于民族问题的重要论述所蕴含的马克思主义政治哲学的价值理性和方法论。基于对政治哲学及马克思主义的政治哲学的理论阐释,从马克思主义历史唯物观与尊重中国各民族历史渊源和历史贡献,... 详细信息

本文试从马克思主义政治哲学的视角,探析习近平关于民族问题的重要论述所蕴含的马克思主义政治哲学的价值理性和方法论。基于对政治哲学及马克思主义的政治哲学的理论阐释,从马克思主义历史唯物观与尊重中国各民族历史渊源和历史贡献,马克思主义“民族平等价值观”与坚持民族平等和民族区域自治,马克思主义有机整体观与“石榴籽理论”和“铸牢中华民族共同体意识”,马克思主义人民价值主体观与“以人民为中心”,马克思主义法治观与依法治理民族事务五个维度分别展开论述。探析习近平关于民族问题重要论述所蕴含的政治哲学价值和政治文明理念,可以更好理解习近平关于民族问题重要论述的思想精髓,从而更好地贯彻执行党的民族理论和民族政策。

关键词：政治哲学价值理性民族平等共同体意识人民价值主体

马克思恩格斯“伟大的历史的民族”论说及启示

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民族研究 2023年第5期 1-9,M0002页

作者：董强贵州民族大学民族学与历史学学院贵阳市550025 中华民族共同体与多民族文化繁荣发展高端智库

马克思和恩格斯在19世纪40年代就提出了“伟大的历史的民族”论说,深刻地辨析了“民族”与“国家”的关系。马克思、恩格斯认为,“伟大的历史的民族”也是“革命的民族”,这样的民族在现代社会具有推动人类社会历史进步的革命性,对现代... 详细信息

马克思和恩格斯在19世纪40年代就提出了“伟大的历史的民族”论说,深刻地辨析了“民族”与“国家”的关系。马克思、恩格斯认为,“伟大的历史的民族”也是“革命的民族”,这样的民族在现代社会具有推动人类社会历史进步的革命性,对现代世界体系具有建构性。中国共产党曾使用“伟大的历史的民族抗战”话语。中华民族近代以来自强不息、救亡图存,尤其是在中国共产党的带领下经过艰苦卓绝的革命斗争建立了中华人民共和国,实现了民族独立和人民解放。经过社会主义革命和建设、改革开放及新时代快速发展后,中国已成为改变国际关系对比格局的重要力量。马克思、恩格斯笔下“伟大的历史的民族”的理念之于中华民族,在中国共产党民族工作的百年征程中得到不断实践。新时代以习近平同志为核心的党中央,提出了“建设中华民族共同体”“铸牢中华民族共同体意识”等论断,深化了中华民族作为“伟大的历史的民族”的理论内涵。“伟大的历史的民族”论说对推进中华民族共同体建设具有重要启示意义。

关键词： “伟大的历史的民族” 中华民族民族工作中华民族共同体建设

Analysis of Maize Heterotic Groups and Patterns During Past Decade in China

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Agricultural Sciences in China 2004年第7期3卷 481-489页

作者： TENGWen-tao CAOQing-sheng CHENYan-hui LIUXiang-hui MENShao-dong JINGXi-qiang LIJian-sheng ChinaAgriculturalUniversity／NationalMaizeImprovementCenterofChina Beijing100094P.R.China

In this investigation, maize heterotic groups and patterns were analyzed based on theplanting areas from 1992 to 2001 using 84 parent lines of 71 widely extended hybrids andclassification results by SSR markers, in which these lines were assigned into sevenheterotic groups based on Ni-LIs genetic distances. The results indicated that acertain extent change for major heterotic groups of maize took place during past decadein China. The major heterotic groups were Lancaster, Reid, Tang SPT, Zi330 and E28 in theearly 1990s, while they became Reid, Tem-tropicⅠ, Zi330, Tang SPT and Lancaster in theearly 21st century. Tem-tropicⅠwas a new heterotic group, which contained tropic maizegermplasm. The changes for heterotic patterns also occurred. Some new heterotic patternscombining with Tem-tropicⅠappeared, such as ReidTem-tropicⅠ, Zi330Tem-tropicⅠ,Tang SPTTem-tropicⅠ, etc.. Another change was the order of heterotic patterns. In theearly and middle 1990s, the top five heterotic patterns were ReidTang SPT, Zi330Lancaster, LancasterTang SPT, LancasterE28 and ReidZi330, while they became ReidTem-tropicⅠ, ReidZi330, ReidTang SPT, Zi330Tem-tropicⅠand LancasterTang SPT inthe early 21 century. ReidTem-tropicⅠand Zi330Tem-tropicⅠwere laid on the firstand forth Chinese heterotic patterns respectively in 2001. These results providedsignificant information to understand the maize heterotic groups and patterns in Chinaat molecular level.

关键词： Maize Heterotic group Heterotic pattern SSR

Inhibitory effects of petasin on human colon carcinoma cells mediated by inactivation of Akt/mTOR pathway

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Chinese Medical Journal 2019年第9期132卷 1071-1078页

作者： Xi Lyu Ai-Lin Song Yin-Liang Bai Xiao-dong Xu dong-qiang He You-Cheng Zhang The 5th Department of General Surgery Lanzhou University Second HospitalLanzhouGansu 730030China Department of Pharmacy Lanzhou University Second HospitalLanzhouGansu 730030China The 2nd Department of General Surgery Lanzhou University Second HospitalLanzhouGansu 730030China

Background:Colorectal cancer is the third most common cancer worldwide and still lack of effective therapy so ***,a natural product found in plants of the genus Petasites,has been reported to possess anticancer *** present study aimed to investigate the anticolon cancer activity of petasin both in vitro and in *** molecular mechanism of petasin was also further ***:Caco-2,LoVo,SW-620,and HT-29 cell lines were used to detect the inhibitory effect of petasin on colon cancer *** viability was determined using the MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) *** apoptosis was analyzed by flow *** 33258 staining was used to visualize morphological *** migration was assessed using a wound-healing migration assay,and cell invasion was investigated using Transwell *** blotting assays were employed to evaluate the expression levels of proteins in the protein kinase B/mammalian target of rapamycin (Akt/mTOR) signaling ***,in vivo activity of petasin was evaluated using the SW-620 subcutaneous tumor model established in Balb/c nude *** rats were randomly divided into control group and 10 mg/kg petasin *** tumor volume was calculated every 7 days for 28 *** deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) assay was performed to assess the apoptotic effect of *** between two groups were assessed by analysis of independent-sample t ***:Petasin significantly inhibited the proliferation of human colon carcinoma cell lines,induced apoptosis,and suppressed migration and invasion in SW-620 *** blotting results showed that petasin decreased the phosphorylation of Akt (1.01 ± 0.16 vs.0.74 ± 0.06,P = 0.042),mTOR (0.71 ± 0.12 vs.0.32 ± 0.11,P = 0.013),and P70S6K (1.23 ± 0.21 vs.0.85 ± 0.14,P = 0.008),elevated the expression of caspase-3 (0.41 ± 0.09 vs.0.74 ± 0.12,P = 0.018) and caspas

关键词： Petasin Colon cancer Apoptosis Migration Invasion Akt/mTOR pathway

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高速铁路引入包头枢纽方案研究

铁道工程学报 2017年第2期34卷 5-10页

作者：董志强铁道第三勘察设计院集团有限公司天津300142

研究目的:京包兰、包海两条高速铁路引入包头枢纽,将对枢纽的客运系统布局产生重大影响,需系统研究,重新架构。本文通过对包头区域路网、城市现状及发展规划、综合交通运输体系等进行深入分析,系统研究提出高速铁路引入包头枢纽方案,旨... 详细信息

研究目的:京包兰、包海两条高速铁路引入包头枢纽,将对枢纽的客运系统布局产生重大影响,需系统研究,重新架构。本文通过对包头区域路网、城市现状及发展规划、综合交通运输体系等进行深入分析,系统研究提出高速铁路引入包头枢纽方案,旨在为枢纽总图研究及设计提供实践案例。研究结论:(1)高速铁路宜沿既有客运通道集中引入包头站;(2)为构筑综合交通枢纽,高速铁路宜结合包头市机场综合交通枢纽规划在机场设站;(3)为实现枢纽点线能力的协调,包头站宜按高普速分场布置,并设置必要的立折车疏解线;(4)该研究结论可为高速铁路引入包头枢纽方案提供借鉴。

关键词：铁路枢纽研究