检索结果-南通市图书馆

Development and validation of a novel criterion of histologic healing in ulcerative colitis defined by inflammatory cell enumeration in lamina propria mucosa:A multicenter retrospective cohort in China

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2024年第11期137卷 1316-1323页

作者： Han gao Kangsheng peng Yadi shi shenshen Zhu Ruicong sun Chunjin Xu ping Liu Zhi pang Lanxiang Zhu Weichang Chen Baisui Feng Huili Wu guangxi Zhou Mingsong Li Junxiang Li Baijing ding zhanju Liu Center for IBD Research and Department of gastroenterology Shanghai Tenth People’s HospitalTongji University School of MedicineShanghai 200085China Clinical Medicine Sanquan College of Xinxiang Medical UniversityXinxiangHenan 453003China Department of gastroenterology The First People’s Hospital of Shangqiu City Affiliated to Xinxiang Medical UniversityShangqiuHenan 476100China Department of gastroenterology Wuhu First People’s HospitalWuhuAnhui 241000China Department of gastroenterology Suzhou Municipal Hospital Affiliated to Nanjing Medical UniversitySuzhouJiangsu 215008China Department of gastroenterology The First Affiliated Hospital of Soochow UniversitySuzhouJiangsu 251006China Department of gastroenterology The Second Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan 450014China Department of gastroenterology Zhengzhou Central Hospital Affiliated to Zhengzhou UniversityZhengzhouHenan 450000China Department of gastroenterology The Affiliated Hospital of Jining Medical CollegeJiningShandong 272004China Department of gastroenterology The Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong 510140China Department of gastroenterology Dongfang Hospital of Beijing University of Chinese MedicineBeijing 100078China

Background:Histological healing is closely associated with improved long-term clinical outcomes and lowered relapses in patients with ulcerative colitis(UC).Here,we developed a novel diagnostic criterion for assessing histological healing in UC ***:We conducted a retrospective cohort study in UC patients,whose treatment was iteratively optimized to achieve mucosal healing at shanghai Tenth people’s Hospital of Tongji University from January 2017 to May *** identified an inflammatory cell enumeration index(ICEI)for assessing histological healing based on the proportions of eosinophils,CD177^(+)neutrophils,and CD40L^(+)T cells in the colonic lamina propria under high power field(HpF),and the outcomes(risks of symptomatic relapses)of achieving histological remission *** histological inflammation using Kaplan-Meier *** reliability and inter-reader reliability were evaluated by each *** relationships to the changes in the Nancy index and the geboes score were also assessed for *** ICEI was further validated in a new cohort of UC patients from other nine university ***:We developed an ICEI for clinical diagnosis of histological healing,i.e.,Y=1.701X_(1)+0.758X_(2)+1.347X_(3)-7.745(X_(1),X_(2),and X_(3)represent the proportions of CD177^(+)neutrophils,eosinophils,and CD40L^(+)T cells,respectively,in the colonic lamina propria under HpF).The receiver operating characteristics curve(ROC)analysis revealed that Ys the cutoff value for the diagnosis of histological healing and that an area under the curve(AUC)was 0.942(95%confidence interval[CI]:0.905-0.979)with a sensitivity of 92.5%and a specificity of 83.6%(pss correlation coefficient(ICC)for the intrareader reliability was 0.855(95%CI:0.781-0.909),and ICEI had good inter-reader reliability of 0.832(95%CI:0.748-0.894).During an 18-month follow-up,patients with histological healing had a substantially better outcome com

关键词： Ulcerative colitis Histological healing Inflammatory cell enumeration index prognosis

A probe into the acid deposition mitigation path in China over the last four decades and beyond

在线全文

学校读者我要写书评

暂无评论

National science Review 2024年第4期11卷 84-92页

作者： Qian Yu Xiaodong ge Haotian Zheng Jia Xing Lei Duan Dongwei Lv Dian ding zhaoxin Dong Yisheng sun posch Maximilian Danni Xie Yu zhao Bin zhao shuxiao Wang Jan Mulder Thorj?rn Larssen Jiming Hao state Key Laboratory of Environmental simulation and pollution Control School of EnvironmentTsinghua University state Key Laboratory of pollution Control &Resource Reuse and school of the Environment Nanjing University state Environmental protection Key Laboratory of sources and Control of Air pollution Complex School of EnvironmentTsinghua University International Institute for Applied system Analysis(IIAsA) school of Land Engineering Chang'an University Faculty of Environmental sciences and Natural Resource Management Norwegian University of Life Sciences Norwegian Institute for Water Research

China currently has the highest acid deposition globally, yet research on its status, impacts, causes and controls is lacking. Here, we compiled data and calculated critical loads regarding acid deposition. The results showed that the abatement measures in China have achieved a sharp decline in the emissions of acidifying pollutants and a continuous recovery of precipitation p H, despite the drastic growth in the economy and energy consumption. However, the risk of ecological acidification and eutrophication showed no significant decrease. With similar emission reductions, the decline in areas at risk of acidification in China(7.0%) lags behind those in Europe(20%) or the UsA(15%). This was because, unlike Europe and the UsA, China's abatement strategies primarily target air quality improvement rather than mitigating ecological impacts. given that the area with the risk of eutrophication induced by nitrogen deposition remained at 13%of the country even under the scenario of achieving the dual targets of air quality and carbon dioxide mitigation in 2035, we explored an enhanced ammonia abatement pathway. With a further 27% reduction in ammonia by 2035, China could largely eliminate the impacts of acid deposition. This research serves as a valuable reference for China's future acid deposition control and for other nations facing similar challenges.

关键词： acid deposition critical loads acidification eutrophication ammonia abatement

单、双侧穿刺经皮椎体后凸成形术治疗老年骨质疏松性椎体压缩骨折的疗效比较

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

临床骨科杂志 2024年第2期27卷 153-157页

作者：江帅查正查兴胜安徽医科大学附属安庆第一人民医院骨二科安徽安庆246003

目的比较单、双侧穿刺经皮椎体后凸成形术(pKp)治疗老年骨质疏松性椎体压缩骨折的疗效。方法将62例行pKp治疗的老年骨质疏松性椎体压缩骨折患者按单、双侧穿刺不同分为单侧组(32例)和双侧组(30例)。比较两组骨水泥注入量及渗漏情况、术... 详细信息

目的比较单、双侧穿刺经皮椎体后凸成形术(pKp)治疗老年骨质疏松性椎体压缩骨折的疗效。方法将62例行pKp治疗的老年骨质疏松性椎体压缩骨折患者按单、双侧穿刺不同分为单侧组(32例)和双侧组(30例)。比较两组骨水泥注入量及渗漏情况、术中X线透视时间、手术时间、术后疼痛VAs评分以及影像学指标。结果患者均获得随访,时间6~13个月。骨水泥注入量、术中X线透视时间、手术时间单侧组均少(短)于双侧组(ps评分两组比较差异无统计学意义(p>0.05)。单侧组3例、双侧组7例发生骨水泥渗漏,但均无临床症状。伤椎前缘高度、伤椎中央高度、Cobb角两组术后均较术前改善(pp>0.05)。结论单、双侧穿刺pKp治疗老年骨质疏松性椎体压缩骨折均能改善患者疼痛症状、纠正脊柱后凸畸形,恢复伤椎高度,单侧穿刺术中X线透视时间和手术时间更短、骨水泥注入量更少。

关键词：单侧穿刺经皮椎体后凸成形术双侧穿刺经皮椎体后凸成形术脊柱胸腰段骨质疏松性椎体压缩骨折

高校图书馆员数据素养培育实践及启示——基于国外案例调查

在线全文

学校读者我要写书评

暂无评论

图书情报工作 2024年第7期68卷 46-56页

作者：罗靖琳刘倩秀查颖钟庆虹深圳大学图书馆深圳518061

[目的/意义]数据素养是高校图书馆员当前应必备的专业核心能力,国内外都在持续探索适合的馆员数据素养培育路径。我国在此方面尚处于起步阶段,调查和研究国外开展的高校图书馆员数据素养培育实践案例,归纳经验启示,有利于为我国馆员数... 详细信息

[目的/意义]数据素养是高校图书馆员当前应必备的专业核心能力,国内外都在持续探索适合的馆员数据素养培育路径。我国在此方面尚处于起步阶段,调查和研究国外开展的高校图书馆员数据素养培育实践案例,归纳经验启示,有利于为我国馆员数据素养培育提供借鉴,提升培育质量。[方法/过程]选取国外12个馆员数据素养培育案例,结合3p教育模型和传播学5W理论,从培育前提、过程、结果三个方面进行分析研究并总结启示。[结果/结论]构建普适性的馆员数据素养培育模型,基于此提出思考,从培育主体、对象、内容、方式、结果等方面提出具体建议。

关键词：数据素养高校图书馆员培育模型

FVIT-YOLO v8:基于多尺度融合注意机制的改进YOLO v8小目标检测

在线全文

学校读者我要写书评

暂无评论

红外技术 2024年第8期46卷 912-922页

作者：刘富宽罗素云何佳查超能上海工程技术大学机械与汽车工程学院上海201620

本文研究了遥感与无人机航拍图像中的小目标检测问题。由于这类图像存在目标尺度小、目标分布密集、背景复杂等特点,使得特征提取困难。目前针对小目标检测的算法,为了提升精度,大多忽略了参数量与推理速度的影响,这使得算法缺乏实用性... 详细信息

本文研究了遥感与无人机航拍图像中的小目标检测问题。由于这类图像存在目标尺度小、目标分布密集、背景复杂等特点,使得特征提取困难。目前针对小目标检测的算法,为了提升精度,大多忽略了参数量与推理速度的影响,这使得算法缺乏实用性。针对上述问题,本文提出了一种基于轻量化的多尺度融合注意机制的改进YOLO v8小目标检测算法。算法首先在YOLO v8的FpN结构中加入F算子,设计了多尺度特征的加权融合;然后在网络预测层剔除了p4、p5预测层,加入p2层用于小目标的预测;最后对轻量化自注意力机制进行图像输入网格化分割整合改进,并用它替换了FpN中的C2f模块,使得算法具有更好的全局感知能力,并大幅降低了参数量。与YOLO v8s相比,本文算法在DOTA数据集上的mAp提升了4.4%,网络参数量下降了52%,Fps达到了46帧/s。在VisDrone数据集中,本算法在精度上提升了8.2%。

关键词： YOLO v8 小目标检测 Transformer 轻量化实时性

在线全文

学校读者我要写书评

暂无评论

食品检测中标准化农药残留检测技术研究

中国标准化 2024年第8期 198-201页

作者：查勇姜琛日照市质量检验检测研究院日照市政务服务中心

农药残留引发的食品安全问题日益受到公众重视,建立科学合理的标准化农药残留检测技术,对保障食品安全意义重大。本文以分析当前农药残留问题现状入手,综述研究进展,介绍目前常见的农药残留检测技术,分析各技术特点、适用范围和优缺点,... 详细信息

农药残留引发的食品安全问题日益受到公众重视,建立科学合理的标准化农药残留检测技术,对保障食品安全意义重大。本文以分析当前农药残留问题现状入手,综述研究进展,介绍目前常见的农药残留检测技术,分析各技术特点、适用范围和优缺点,提出实现标准化农药残留检测的设想与创新策略,旨在为我国食品安全工作提供参考。

关键词：食品检测标准化农药残留检测

Organic matter accumulation in lacustrine shale of the permian Jimsar sag,Junggar Basin,NW China

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

petroleum science 2023年第3期20卷 1327-1346页

作者： Xiu-Jian ding Wen-Jun He Hai-Lei Liu Xu-guang guo Ming zha Zhong-Fa Jiang school of geosciences in China University of petroleum QingdaoShandong266580China Research Institute of petroleum Exploration and Development PetroChina Xinjiang Oilfield CompanyKaramayXinjiang841000China

The lacustrine organic-rich shale in the permian Lucaogou(LCg)Formation of the Jimsar sag,Junggar Basin,is one of the main shale oil plays in *** this paper,geological and geochemical research techniques were employed to evaluate the geochemical variability of the lacustrine shale and the pro-duction of organic matter and its preservation *** Lcg Formation is characterized by its complex mineral compositions and a wide range of organic matter richness and *** presence of high proportions ofβ-carotane and C2g steranes,indicates that the organic matter mainly originated from phytoplankton and aquatic algal-bacterial organisms,especially *** study found that the productivity of the Lower LCg Member(p2li)was highest,and the Middle LCg Member(p_(2)l_(2))was the *** the deposition of the Lower LCg Member,the lake's bottom water was predominantly a reducing environment,and the degradation of organic matter was largely a result of bacterial sulfate *** the deposition of the Middle and Upper LCg members,the lake's bottom water was mainly oxidizing,and the degradation of organic matter was likely to be caused by aerobic *** on a comprehensive analysis of the origin and production of organic matter,as well as its depo-sitional environment and preservation conditions,two organic matter accumulation models were pro-posed to explain the distribution of the organic-rich *** model A,the high influx of volcanic ash released nutrients and brought abundant sulfate into the water,the accumulation of organic matter was mainly controlled by the preservation of organic matter,which was mainly controlled by *** the model B,the influx of volcanic ash was small,organic matter was mainly degraded by oxygen and the accumulation of organic matter is mainly determined by the production of organic matter.

关键词： Lucaogou formation Jimsar sag Organic-matter-rich shale Organic matter accumulation Organic matter productivity Bacterial sulfate reduction

Diagnostic efficacy of virtual organ computer-assisted analysis in measuring the volume ratio of subchorionic hematoma with serum progesterone

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第17期12卷 3053-3060页

作者： Lin-Ling shen Jing shi Chang-Wei ding gao-Le Dai Qi Ma Department of Ultrasound The Second Affiliated Hospital of Soochow UniversitySuzhou 215004Jiangsu ProvinceChina Department of Ultrasound Wuxi People’s Hospital of Nanjing Medical UniversityWuxi 211103Jiangsu ProvinceChina

BACKgROUND subchorionic hematoma(sCH)is a common complication in early pregnancy characterized by the accumulation of blood between the uterine wall and the chorionic *** can lead to adverse pregnancy outcomes such as miscarriage,preterm birth,and other *** detection and accurate assessment of sCH are crucial for appropriate management and improved pregnancy *** To evaluate the diagnostic efficacy of virtual organ computer-assisted analysis(VOCAL)in measuring the volume ratio of sCH to gestational sac(gs)combined with serum progesterone on early pregnancy outcomes in patients with *** A total of 153 patients with sCH in their first-trimester pregnancies between 6 and 11 wk were *** patients were followed up until a gestational age of 20 *** parameters of transvaginal two-dimensional ultrasound,including the circumference of sCH(Cs),surface area of sCH(ss),circumference of gs(Cg),and surface area of gs(sg),and the parameters of VOCAL with transvaginal three-dimensional ultrasound,including the three-dimensional volume of sCH(3DVs)and gs(3DVg),were *** size of the sCH and its ratio to the gs size(Cs/Cg,ss/sg,3DVs/3DVg)were recorded and *** Compared with those in the normal pregnancy group,the adverse pregnancy group had higher Cs/Cg,ss/sg,and 3DVs/3DVg ratios(ps/3DVg was 0.220,the highest predictive performance predicted adverse pregnancy outcomes,resulting in an AUC of 0.767,and the sensitivity,specificity were 70.2%,75%*** measuring 3DVs/3DVg combined with serum progesterone gave a diagnostic AUC of 0.824 for early pregnancy outcome in sCH patients,with a high sensitivity of 82.1%and a specificity of 72.1%,which showed a significant difference between *** VOCAL-measured 3DVs/3DVg effectively quantifies the severity of sCH,while combined serum progesterone better predicts adverse pregnancy outcomes.

关键词： subchorionic hematoma Virtual organ computer-assisted analysis gestational sac serum progesterone Ultrasound parameters Adverse pregnancy outcomes

ADC值评估原发性干燥综合征唾液腺淋巴结炎性的应用价值

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

磁共振成像 2024年第5期15卷 68-74页

作者：田曼婷丁长伟中国医科大学附属盛京医院放射科沈阳110004

目的探讨原发性干燥综合征(primary sj?gren’s syndrome,pss)患者治疗前后唾液腺引流区淋巴结的表观扩散系数(apparent diffusion coefficient,ADC)值和形态变化及其在反映pss患者疾病炎性活动程度的潜在可能性。材料与方法收集23例ps... 详细信息

目的探讨原发性干燥综合征(primary sj?gren’s syndrome,pss)患者治疗前后唾液腺引流区淋巴结的表观扩散系数(apparent diffusion coefficient,ADC)值和形态变化及其在反映pss患者疾病炎性活动程度的潜在可能性。材料与方法收集23例pss患者,分别于治疗前、规律治疗12周后行常规头颈部MRI与扩散加权成像(diffusion weighted imaging,DWI)检查,经过后处理得到ADC图像。与15例健康志愿者对照,使用t检验比较pss患者治疗前后、健康志愿者各区淋巴结的形态及ADC值。结果pss患者治疗前Ⅰb、Ⅱa、Ⅱb区淋巴结短径均大于健康志愿者[Ⅰb(t=2.293,p=0.028)、Ⅱa(t=2.397,p=0.022)、Ⅱb(t=1.409,p=0.030)],治疗12周后唾液腺引流各区淋巴结短径均较治疗前减小[Ⅰa(t=4.391,pp=0.002)、Ⅱa(t=3.458,p=0.002)、Ⅱb(t=4.667,p=0.001)]。pss患者治疗前Ⅰb、Ⅱa区淋巴结ADC值小于健康志愿者[Ⅰb(t=3.337,p=0.002)、Ⅱa(t=2.207,p=0.038)],治疗12周后Ⅰa、Ⅰb、Ⅱa区淋巴结ADC值大于治疗前[Ⅰa(t=3.674,p=0.001)、Ⅰb(t=2.198,p=0.039)、Ⅱa(t=2.484,p=0.004)]。结论Ⅰb、Ⅱa、Ⅱb区淋巴结短径在鉴别pss患者与健康志愿者可能具有应用价值,唾液腺引流各区淋巴结短径在鉴别pss患者自身治疗前后可能具有应用价值;Ⅰb、Ⅱa区淋巴结ADC值在鉴别pss患者与健康志愿者可能具有应用价值,Ⅰa、Ⅰb、Ⅱa区淋巴结ADC值在鉴别pss患者自身治疗前后可能具有应用价值。

关键词：自身免疫性疾病原发性干燥综合征疾病炎性活动程度扩散加权成像表观扩散系数磁共振成像