检索结果-南通市图书馆

Adaptive sampling algorithm for detection of superpoints

在线全文

学校读者我要写书评

暂无评论

Science in China(Series F) 2008年第11期51卷 1804-1821页

作者： CHENG Guang GONG Jian ding wei WU hua QIANG ShiQiang Key Lab of Jiangsu Computer Network School of Computer Science and Engineering Southeast University Nanjing 210096 China

The superpoints are the sources （or the destinations） that connect with a great deal of destinations （or sources） during a measurement time interval, so detecting the superpoints in real time is very important to network security and management. Previous algorithms are not able to control the usage of the memory and to deliver the desired accuracy, so it is hard to detect the superpoints on a high speed link in real time. In this paper, we propose an adaptive sampling algorithm to detect the superpoints in real time, which uses a flow sample and hold module to reduce the detection of the non-superpoints and to improve the measurement accuracy of the superpoints. We also design a data stream structure to maintain the flow records, which compensates for the flow Hash collisions statistically. An adaptive process based on different sampling probabilities is used to maintain the recorded IP addresses in the limited memory. This algorithm is compared with the other algorithms by analyzing the real network trace data. Experiment results and mathematic analysis show that this algorithm has the advantages of both the limited memory requirement and high measurement accuracy.

关键词： superpoints detection adaptive process flow sample and hold collision compensation

Oxidative cyclization of allyl compounds and isocyanide: A facile entry to polysubstituted 2-cyanopyrroles

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第4期35卷 330-335页

作者： Yaping Zhang wei Zhou Mingchun Gao Tianqi Liu Bingxin Liu Chang-hua ding Bin Xu Department of Chemistry Affiliated Nantong Hospital of Shanghai University(The Sixth People's Hospital of Nantong)Shanghai Engineering Research Center of Organ RepairInnovative Drug Research CenterSchool of MedicineShanghai UniversityShanghai 200444China State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032China

A facile Tf OH-catalyzed oxidative cyclization of allyl compounds and isocyanide has been developed with the assistance of DDQ, where isocyanide is used as the crucial "N" and "CN" sources. Highly functionalized 2-cyanopyrroles are constructed efficiently through a new formal [3 + 2] mode, demonstrating diverse reactivity and synthetic utility in organic chemistry. 2-Cyanopyrrole is converted into a nucleobase analogue of Remdesivir and 5H-pyrrolo[2,1-a]isoindole through a three-step or a two-step sequence, respectively. This protocol features broad substrate scope, operational simplicity and good functional group tolerance.

关键词： Isocyanide Cyanopyrrole Insertion Allyl compound Bronsted acid catalysis

Optimized Benzalkonium Chloride Gel: A Potential Vaginal Microbicides

在线全文

学校读者我要写书评

暂无评论

Journal of Reproduction and Contraception 2007年第2期18卷 89-92页

作者： Xun-cheng ding wei-hua LI Jie-fei LI Qiang-yi WANG Shanghai Institute of Planned Parenthood Research Shanghai 200032 China

Objective To develop an optimized BZK gel with good pharmaceutical effect and less toxicity to vaginal mucosa. Methods Four methods as below were used to research the spermicidal activity of BZK gel： 1） in vitro spermicidal test; 2） in vivo spermicidal test in rabbits; 3） anti-fertility test in rabbits; 4） contraceptive test in rabbits. Mucosal irritation test was used in rats to evaluate the safety of optimized BZK gel. Microbiological assessments were used to research anti-STI pathogens （including treponema pallidum, neisseria gonorrhoeae, trichomona vaginalis, candida albicans, ureaplama urealyticum, herpes simplex virus type-2, chlamydiae trachomatis） effect of optimized BZK gel. Results In vitro spermicidal test, EC50 of BZK gel was 0.029mg/ml, a little higher than that of N-9 （0.019mg/ml）. The MIC of BZK gel was 0.25mg/ml, similar to that of N-9 （0.20mg/ml）. The vaginal mucosal irritation test in rats showed that 0.429% BZK gel showed only minimal vaginal irritation, and did not damage the vaginal epithelium or cause local inflammation in rats. Microbiological assessments showed that optimized BZK gel could inhibit or inactivate common ST1 pathogens even after 3-fold or 5-fold dilution. Conclusion Optimized BZK gel was an effective microbicides.

关键词： Benzalkonium Chloride microbicides contraception HIV/AIDS

Climate services for addressing climate change: Indication of a climate livable city in China

在线全文

学校读者我要写书评

暂无评论

Advances in Climate Change Research 2021年第5期12卷 744-751页

作者： WANG Yu-Jie CHEN Yu Chris HEWITT ding wei-hua SONG Lian-Chun AI Wan-Xiu HAN Zhen-Yu LI Xiu-Cang huaNG Zi-Li Key Laboratory of Meteorological Disaster Ministry of Education/International Joint Research Laboratory on Climate and Environment Change/Collaborative Innovation Center on Forecast and Evaluation of Meteorological DisastersNanjing University of Information Science and TechnologyNanjing210044China School of Atmospheric Sciences Nanjing University of Information Science and TechnologyNanjing210044China Laboratory for Climate Change National Climate CenterChina Meteorological AdministrationBeijing100081China Met Office ExeterEX13BPUK University of Southern Queensland ToowoombaQld4350Australia Jiande Meteorological Service Zhejiang Meteorological BureauHangzhou311600China

China, like many countries, is under great pressure to reduce climate change and adapt to current situations while simultaneously undertaking economic development and transformation. This study takes advantage of climate opportunities and provides a new concept and mode of urban climate services in order to address climate change. Eighteen indicators based on climate and climate-related variables were used to provide an assessment, in the form of an index, of how livable a city is depending on prevailing climatic conditions. The resulting index can also be used to investigate how recent and future changes in the climatic conditions could affect livability. All Chinese cities and regions share the common goals of promoting low-carbon development, improving resilience against climate change, and integrating economic growth with climate actions. Climate services have been developed in China to provide decision-makers this measure of livability. Such a move facilitates sustainable development alongside economic growth by aiding government efforts in climate adaptation and low-carbon development. Our approach represents multidisciplinary and demand-driven research on adaptation to and the impacts of regional climate change, thereby transforming climate science into a climate service and ensuring that climate information can be provided in a scientific, practical, and customized way for policy-makers. The outputs can be used locally to take concrete climate actions and integrate climate services into decision-making processes.

关键词： Climate services Addressing climate change Climate livable city China

The crosstalk between enteric nervous system and immune system in intestinal development,homeostasis and diseases

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2024年第1期67卷 41-50页

作者： Xindi Wang Chenbo ding hua-Bing Li Shanghai Institute of Immunology State Key Laboratory of Oncogenes and Related GenesShanghai Jiao Tong University School of MedicineShanghai 200025China Shanghai Jiao Tong University School of Medicine-Yale Institute for Immune Metabolism Shanghai Jiao Tong University School of MedicineShanghai 200025China

The gut is the largest digestive and absorptive organ,which is essential for induction of mucosal and systemic immune responses,and maintenance of metabolic-immune *** intestinal components contain the epithelium,stromal cells,immune cells,and enteric nervous system(ENS),as well as the outers,such as gut microbiota,metabolites,and *** dyshomeostasis of intestinal microenvironment induces abnormal intestinal development and functions,even colon diseases including dysplasia,inflammation and *** recent studies have identified that ENS plays a crucial role in maintaining the immune homeostasis of gastrointestinal(GI)*** crosstalk between ENS and immune cells,mainly macrophages,T cells,and innate lymphoid cells(ILCs),has been found to exert important regulatory roles in intestinal tissue programming,homeostasis,function,and *** this review,we mainly summarize the critical roles of the interactions between ENS and immune cells in intestinal homeostasis during intestinal development and diseases progression,to provide theoretical bases and ideas for the exploration of immunotherapy for gastrointestinal diseases with the ENS as potential novel targets.

关键词： enteric nervous system macrophages T cells innate lymphoid cells neuro-immune interactions

Optical system for extremely large spectroscopic survey telescope

在线全文

学校读者我要写书评

暂无评论

Science China(Physics,Mechanics & Astronomy) 2024年第7期67卷 158-174页

作者： ding-qiang Su hua Bai Xiangyan Yuan Xiangqun Cui Key Laboratory of the Ministry of Education School of Astronomy and Space ScienceNanjing UniversityNanjing 210023China Nanjing Institute of Astronomical Optics and Technology(NIAOT) Chinese Academy of SciencesNanjing 210042China University of Chinese Academy of Sciences Nanjing 211135China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 101408China

This article presents research work on a spectroscopic survey *** idea is as follows:for such a telescope,a pure reflecting optical system is designed,which should have an aperture and a field of view(FOV)both as large as possible and excellent image quality,and then a strip lensm(lens-prism)atmospheric dispersion corrector(S-ADC)is added,only for correcting the atmospheric *** the fund limitation and the simplicity of scaling up,some 12-m telescopes are designed as ***,Korsch,and Meinel put forward the four-mirror Nasmyth systems I and II,which are used in this *** of 1.5°,2°,and 2.5°are *** all systems,the image qualities are *** the S-ADC relaxes the optical glass size restriction,this 12-m telescope with a FOV of 2.5°can be magnified in proportion to a 16-m *** etendue(from Frenchétendue)and focal surface will now be the largest in the *** such a telescope,a pure reflecting optical system can also be obtained.A subsequent coudésystem is designed with excellent image quality.

关键词： telescopes spectroscopic survey

Honeycomb-like MoCo alloy on 3D nitrogen-doped porous graphene for efficient hydrogen evolution reaction

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2024年第3期43卷 1072-1082页

作者： Lin-Ping Wang Kuang Li hua-Long ding Le Xu Chen huang Jiao-Jiao Zhou Cong-TaoWen Pei-Lin Zhang wei-wei Wang Lu-Yang Chen Key Laboratory for Ultrafine Materials of Ministry of Education School of Materials Science and EngineeringEast China University of Science and TechnologyShanghai200237China State Key Laboratory of High-Performance Ceramics and Superfine Microstructure Shanghai Institute of Ceramics Chinese Academy of SciencesShanghai200050China State Key Laboratory of Chemical Engineering and School of Chemistry and Molecular Engineering East China University of Science and TechnologyShanghai200237China

An efficient electrocatalyst is indispensable to significantly reduce energy consumption and accelerate the conversion efficiency of water *** this work,the honeycomb-like porous MoCo alloy on nitrogen-doped three-dimensional(3D)porous graphene substrate(Mo_(0.3)Co_(0.7)@NPG)has been synthesized from the annealing of layered double hydroxide(MoCo-LDH@NPG).Especially,the Mo_(0.3)Co_(0.7)@NPG exhibits low hydrogen evolution overpotential of 75 mV(10 mA·cm^(-2))and a Tafel slope of 69.9 mV·dec^(-1),which can be attributed to highly conductive NPG substrate,the unique nanostructure and the synergistic effect of Mo and ***,the Mo_(0.3)Co_(0.7)@NPG can maintain the original morphology and high catalytic activity after 50-h stability *** work proposes a general strategy to synthesize a multi-element alloy on conductive substrates with high porosity for electrocatalytic reaction.

关键词： MoCo alloy Three-dimensional nitrogen-doped porous graphene Hydrogen evolution reaction(HER)

Wireless multisite sensing systems for continuous physiological monitoring

在线全文

学校读者我要写书评

暂无评论

Science China Materials 2024年第6期67卷 2045-2047页

作者： Ruilai wei Qilin hua Guozhen Shen School of Integrated Circuits and Electronics Beijing Institute of TechnologyBeijing 100081China Institute of Flexible Electronics Beijing Institute of TechnologyBeijing 102488China

Respiratory diseases rank as the third leading cause of adult mortality[1],while cardiopulmonary and gastrointestinal issues are the primary cause of death within the first five years of a child’s life[2].The monitoring of cardiac,respiratory,and gastrointestinal sounds plays a vital role in routine care,as alterations or absence of these body sounds can serve as indicators of underlying diseases.

关键词： routine continuous monitoring

An improved interval model updating method via adaptive Kriging models

在线全文

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2024年第3期45卷 497-514页

作者： Sha wei Yifeng CHEN Hu ding Liqun CHEN Shanghai Key Laboratory of Mechanics in Energy Engineering Shanghai Frontier Science Center of MechanoinformaticsShanghai Institute of Applied Mathematics and MechanicsSchool of Mechanics and Engineering ScienceShanghai UniversityShanghai 200072China Shanghai Institute of Aircraft Mechanics and Control Shanghai 200092China

Interval model updating(IMU)methods have been widely used in uncertain model updating due to their low requirements for sample ***,the surrogate model in IMU methods mostly adopts the one-time construction *** makes the accuracy of the surrogate model highly dependent on the experience of users and affects the accuracy of IMU ***,an improved IMU method via the adaptive Kriging models is *** method transforms the objective function of the IMU problem into two deterministic global optimization problems about the upper bound and the interval diameter through universal grey *** optimization problems are addressed through the adaptive Kriging models and the particle swarm optimization(PSO)method to quantify the uncertain parameters,and the IMU is *** the construction of these adaptive Kriging models,the sample space is gridded according to sensitivity *** sampling is then performed in key subspaces based on the maximum mean square error(MMSE)*** interval division coefficient and random sampling coefficient are adaptively adjusted without human interference until the model meets accuracy *** effectiveness of the proposed method is demonstrated by a numerical example of a three-degree-of-freedom mass-spring system and an experimental example of a butted cylindrical *** results show that the updated results of the interval model are in good agreement with the experimental results.

关键词： interval model updating(IMU) non-probabilistic uncertainty adaptive Kriging model surrogate model grey number