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Genes & Diseases 2023年第1期10卷 239-253页

作者： Kun Zhang Xian Qin Juhui Qiu Tong Sun Kai Qu ahmad Ud din Wenhua Yan Tianhan Li Yidan Chen Wei Gu Xiancai Rao Guixue Wang Key Laboratory for Biorheological Science and Technology of Ministry of Education State and Local Joint Engineering Laboratory for Vascular ImplantsCollege of BioengineeringChongqing UniversityChongqing 400044China College of Information and Management Sciences Henan Agricultural UniversityZhengzhouHenan 450046China School of Medicine Chongqing UniversityChongqing 400030China Department of Microbiology College of Basic Medical SciencesArmy Medical University(Third Military Medical University)Chongqing 400037China

It is increasingly aware that gut microbiota is closely associated with ***,which and how specific gut bacteria regulate the progression of atherosclerosis is still poorly *** this study,modified linear discriminant analysis was performed in comparing the gut microbiota structures of atherosclerotic and non-atherosclerotic mice,and Desulfovibrio desulfuricans(***)was found to be associatedwith ***-treated Apoe^(-/-) mice showed significantly aggravated *** proatherogenic effect of *** was attributed to its ability to increase intestinal permeability and subsequent raise in the transit of lipopolysaccharide(LPS)from the intestine to the *** LPS in the blood can elicit local and systemic inflammation and activate Toll-like receptor 4(TLR4)/nuclear factor-kB(NF-kB)signaling of endothelial ***-242,a specific inhibitor of TLR4,can ameliorate the development of *** atherosclerosis by blocking the LPS-induced activation of TLR4/NF-kB signaling.

关键词： Atherosclerosis Desulf ovibrio desulfuricans Gut microbiota Linear discriminant analysis TAK-242

Distinctive Bullet Impact Holes by 9‑mm Caliber Projectile on Sheet Metal Surfaces

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Journal of Forensic Science and Medicine 2022年第3期8卷 97-103页

作者： Syamsul Anuar Abd Malik Farah Ad‑din Nordin Saiful Fazamil Mohd Ali ahmad Fahmi Lim Abdullah Kah Haw Chang Forensic Science Programme School of Health SciencesHealth CampusUniversiti Sains MalaysiaKubang KerianKelantan Department of Chemistry Division of CriminalisticsForensic Science Analysis CentrePetaling JayaMalaysia

Introduction:A comprehensive scene reconstruction requires forensic investigators to examine the impact marks left on various surfaces to identify whether a projectile produces a specific ***,it is further necessary to determine whether a particular ammunition has caused the *** history,designs of ammunition have evolved with the intended effects,which could leave different impact marks on a target surface,especially by ammunition with a nonconventional *** examination on impact marks and determination of their specific characteristics on sheet metal of vehicle would provide crucialforensic ***:This study was aimed to physically characterize bullet impact holes made by 11 types of 9-mm caliber *** and Methods:Two automotive doors were shot with different ammunitionsfrom the same firearm,and the morphological features of bullet impact holes were observed and ***:Bullet impact holes produced by the various ammunitions could be differentiated through careful observation of bullet hole circumferences,presence of petalling effect,metallic ring and triangular peak at the edge,and deposition of residue at the peripheral area of bullet impact *** with nonconventional design such as Inceptor‑Polycase and GECO Hexagon showed observable morphological differences and discriminated them from bullet impact holes made by conventional ***:A thorough physical examination could aid in distinguishing bullet impact holes and predicting the possible types of ammunition that had made an impact hole on a surface.

关键词： Forensic science bullet hole physical examination Introduction projectile sheet metal

Dermatomal Somatosensory Evoked Potentials: An Indicator of Improvement of Breast Sensibility after Reduction Mammaplasty

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Neuroscience & Medicine 2016年第3期7卷 106-113页

作者： Mohammad Abu-Hegazy Wael Gabr Hossam El-din A. Ismail ahmad A. Khalil Department of Neurology Mansoura University Mansoura Egypt Department of Plastic and Reconstructive Surgery Mansoura University Mansoura Egypt

Introduction: Many women think about reduction mammaplasty for different reasons. The effect of surgery on the beast sensibility is one of the greatest concerns after reconstructive reductive breast surgery through its affect on patient’s social life and psychological health. The dermatomal somatosensory evoked potential (D-SEP) is a new method to quantitatively evaluate breast sensibility. Patients and Methods: Twenty-five women enrolled in this study presenting with breast enlargement, underwent mammary reduction by using the inferior pyramidal breast reduction technique using the same operative technique described by Robbins with some modifications. All D-SEP amplitudes and latencies were calculated preoperatively and then were reassessed six and twelve months post-surgery in each breast. Result: The results revealed that there is a significant difference in the D-SEP latency pre- and post-operatively. The statistically significant decrease in latency and the breast size demonstrated indicates that the sensibility improved after breast reduction surgery both at six and twelve months. There is also a significant increase in the D-SEP amplitude pre- and post-operatively. The negative and statistically significant increase in amplitude with the decrease in breast size demonstrated indicates that the sensibility improved after breast reduction surgery both at six and twelve months. Conclusion: This study concluded that breast sensibility will improve after breast reduction as indicated by significant reduction of D-SEP latencies and increase of its amplitudes. Our results confirm an inverse relationship between breast size and sensibility, with improvement in sensibility after breast reduction.

关键词： Breast Sensibility Reduction Mammoplasty Dermatomal Somatosensory Evoked Potentials

Investigation on the pre-compensation and post-compensation cascaded multi-channel-chirped fiber Bragg gratings for a repeaterless transmission system

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Chinese Optics Letters 2018年第4期16卷 45-50页

作者： K.Khairi H.Fong Kok Z.Lambak M.I.Abdan M.A.Farhan M.H.Othman M.L.H.Jamaluddin S.A.Mohamad Rofie Tee din Chai K.Chia Ching A.Mohd.Ramli M.A.Mokhtar S.A.Syed ahmad M.Mokhtar S.B.ahmad Anas M.A.Mahdi TM Research & Development Sdn.Bhd. Lingkaran Teknokrat Timur Wireless and Photonics Network Research Center Department of Computer & Communication Systems EngineeringFaculty of Engineering Universiti Putra Malaysia

We experimentally designed dispersion-managed repeaterless transmission systems with a pre-compensation and post-compensation technique using multi-channel-chirped fiber Bragg gratings. The repeaterless transmission link supports a single channel（1548.51 nm） with a 10 Gbps repeaterless transmission system over 300 km standard single-mode fiber（SSMF）. In the system design, two distributed Raman amplifiers（DRAs） were used to improve the signal level propagated along the 300 km SSMF. The co-propagating DRA provided 15 dB on–off gain and the counter-propagating produced 32 dB on–off gain at the signal wavelength. The experiment results show that the post-compensation configuration achieves an optimal performance with a bit error rate at 1 × 10-9.

关键词： MC DRA Investigation on the pre-compensation and post-compensation cascaded multi-channel-chirped fiber Bragg gratings for a repeaterle WDM NRZ

The Assessment of Carbon Stocks in the Oak Scrub Forest of Sheringal Valley Dir Kohistan

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Open Journal of Forestry 2015年第5期5卷 510-517页

作者： Alamgir Khan Adnan ahmad Ziaur Rahman Siraj-ud-din Rahmatullah Qureshi Juma Muhammad Department of Forestry Shaheed Benazir Bhutto University Sheringal Dir Upper Pakistan Department of Botany University of Peshawar Peshawar Pakistan Department of Botany PMAS-Arid Agriculture University Rawalpindi Rawalpindi Pakistan Department of Environmental Sciences Shaheed Benazir Bhutto University Sheringal Dir Upper Pakistan

The present study estimates carbon stocks (C-stocks) of the Oak scrub forest of Sheringal valley through field inventory. Stem density (haǃ), tree height (m), basal area (m2·haǃ), stem volume (m2·haǃ), stem biomass (t·haǃ), total biomass (t·haǃ), and total C-stock (t·haǃ), were calculated. Stem density varied between 80±8.16 to 510 ± 42 trees haǃ, with a mean value of 226 ± 7 tress haǃ. The average tree height, basal area and stem volume were 5.47 ± 0.76 m, 12.82 ± 0.25 m2·haǃ and 46.37 ± 0.85 m3·haǃ respectively. The total calculated stem biomass was 32.46 ± 0.60 t·haǃ and total tree biomass was 51.61 ± 0.60 t·haǃ. The calculated C-stocks in the Oak scrub forest ranged from 2.005 ± 1.32 t·haǃ to 63.1 ± 3.34 t·haǃ and the mean C stocks was 25.80 ± 0.47 t·haǃ. The results of the study confirmed that the Oak scrub forest acts as a valuable sink of carbon, but this valuable storage factory of carbon faced the problems of excess uses for fuel wood, forage, domestic uses (mostly for construction) and unscientific management. Proper scientific management and proper utilization of the forest can be significant measures to enhance the potential of the forest to stored and sink more carbon and can be included for CDM and REED++ under Keyto protocol.

关键词： Sheringal Oak Scrub Forest Biomass and Carbon Stocks

Etiologies of tropical acute febrile illness in West Pahang, Malaysia: A prospective observational study

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Asian Pacific Journal of Tropical Medicine 2020年第3期13卷 115-122页

作者： Alif Adlan Mohd Thabit Mohd Hatta Abdul Mutalip Wan Mohd Rasis Wan ahmad Kamil Mohd RamadhanMohd din Mohan Arumugam Siti Sanaa Wan Azman Roslinda Jaafar Sathvinder Singh Gian Singh RafidahAbdullah Eida Nurhadzira Muhammad Nor Asiah Muhamad Department of Medicine Hospital Bentong BentongPahangMalaysia Institute for Public Health National Institute of HealthMalaysiaMinistry of Health MalaysiaSelangorMalaysia Department of Medicine Hospital Sultan Haji ahmad Shah TemerlohPahangMalaysia Department of Pathology Hospital Sultan Haji ahmad Shah TemerlohPahangMalaysia Department of Medicine Hospital Kuala Lipis Kuala LipisPahangMalaysia

Objective: To determine the etiologies of tropical acute febrile illness(TAFI) in West Pahang, Malaysia and to investigate morbidity and mortality factors in relation to TAFI. Methods: A multicenter prospective cohort study was conducted between January and June 2016 in six district hospitals throughout the western part of Pahang State in Peninsular Malaysia. A total of 336 patients answered a standardized questionnaire and blood samples were collected for laboratory confirmation of infectious etiology. Descriptive analysis and logistic regression were performed to identify factors associated with TAFI. Results: A total of 336 patients were included. The patients were mainly Malays(70.2%), males(61.3%), aged(44.6±17.4) years, with more than half(58.9%) presenting with gastrointestinal symptoms. The majority were diagnosed with dengue(35.7%) while malaria(4.5%) was the least frequent. The in-hospital mortality due to TAFI was 9.2%. Patients with meliodosis had five times higher mortality [Adjusted OR: 5.002, 95% CI:(1.233, 20.286)]. Patients with comorbidities such as cardiovascular symptoms(P<0.001) and renal replacement therapy initiation(P<0.001) were significantly associated with in-hospital mortality in all TAFI. Conclusions: The etiology of TAFI in the western Pahang includes dengue, leptospirosis, malaria and melioidosis, which carry the highest risk of in-hospital mortality. The presence of cardiovascular symptoms may be used to assess the disease severity in TAFI, but more studies are needed in the future.

关键词： Comorbidities Mortality Tropical acute febrile illness

Analysis of Bifenthrin Degrading Bacteria from Rhizosphere of Plants Growing at Tannery Solid Waste

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American Journal of Plant Sciences 2015年第13期6卷 2042-2050页

作者： Mukhtar Ahmed Farkhanda Jabeen Muhammad Ali Zarnab ahmad Fayyaz Ahmed Muhammad Bilal Sarwar Salah ud din Mubbashir Hassan Shah Jahan Centre of Excellence in Molecular Biology University of the Punjab Lahore Pakistan Department of Botany University of the Punjab Lahore Pakistan

Bifenthrin is an insecticide which is used to control insects, mites, and ticks. It poses a solemn en-vironmental threat and health risk to living organisms. It may be bioaccumulated or biomagnified at different trophic levels in the food chain by biota. Microbes are hidden creature of earth’s biodiversity. For isolation of bifenthrin degrading bacteria, rhizospheric soil samples of plants like Pisum sativum, Triticun aestvum, Chenopodium album were taken from tannery solid waste, Kasur, Pakistan. Enrichment culture techniques were used for the isolation of bacterial strains that showed luxurious growth on minimal growth media with bifenthrin dose was selected for biodegradation study. Bacteria were further screened out based on their morphological, biochemical parameters and degradation efficiency. Furthermore the effect of different growth factors like temperature, pH, inoculum concencentration, minimal inhibitory concentration of heavy metals and antibiotics were also studied. Bacterial strains of Xanthomonas and Bacillus sp. were identified as efficient degrading microbes. Maximum bifenthrin utilization were observed at 25°C (pH 7), with 500 μL inoculum of Bacillus sp., while Xanthomonas sp. gave optimm utilization at 30°C (pH 7) at the same inoculum volume of bacteria. The Rf values of Bacillus sp. and Xanthomonas sp. were 0.91 and 0.90 respectively, which indicated their potential to metabolize bifenthrin into nontoxic forms. These strains can be used to clean up the sites polluted with pesticides and tannery wastes when present in rhizosphere of plants.

关键词： Bifenthrin Biodegradation Tannery Solid Waste Rhizosphere

Ethnobotanical Study of Medicinal Plants of Semi-Tribal Area of Makerwal &Gulla Khel (Lying between Khyber Pakhtunkhwa and Punjab Provinces), Pakistan

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American Journal of Plant Sciences 2013年第1期4卷 98-116页

作者： Amin Shah Sarfaraz Khan Marwat Faryal Gohar Ameer Khan Khizar Hayat Bhatti Muhammad Amin Noor Ud din Mushtaq ahmad Muhammad Zafar Department of Biological Sciences University of Sargodha Sargodha Pakistan Department of Botany Institute of Chemical and Biological Sciences University of Gujrat Gujrat Pakistan Department of Chemistry University of Sargodha Sargodha Pakistan Department of Plant Sciences Quaid-i-Azam University Islamabad Pakistan University Wensam College Gomal University Dera Imail Khan Pakistan

This paper is based on the results of an ethnomedicinal research work conducted in the semi-tribal mountainous area lying between District Mianwali (PunjabProvince) and District Karak (KhyberPakhtunkhwaProvince),Pakistanduring June 2009-July 2011. During field survey, questionnaires were used to interview the local inhabitants of the area. The ethnomedicinal data consists of 131 plant species (2 Pteridophytes, 7 Monocots, 122 Dicots) belonging to 48 families (2 Pteridophytes, 4 Monocots, 42 Dicots). The most commonly represented families were Amaranthaceae (9 spp.), Mimosaceae (8 spp.), Asteraceae and Papilionaceae (7 spp.) each;Solanaceae, Euphorbiaceae and Scrophulariaceae (6 spp.) each, followed by Boraginaceae, Brassicaceae, Lamiaceae and Polygonaceae (5 spp.) each. Plant specimens were identified, preserved and vouchers were deposited in the Plant Taxonomy Lab. of Department of Biological Sciences,University of Sargodha,Pakistanfor future reference. The data collected through interviews with the local people indicates that these species are mostly used in respiratory tract infections (RTI), urinary tract infections (UTI), digestive disorders, sexual problems, skin diseases, liver ailments, wound healing, blood vomiting, malaria, piles, epilepsy, jaundice, gummosis, round worms, hepatitis etc. in the area. Due to lack of scientific approach regarding harvesting and utilization of this valuable medicinal flora, many plants are quickly going towards extinction;therefore, further work is needed to create awareness in the community conservation of the precious medicinal plants.

关键词： Ethnobotanical Study Medicinal Plants Makerwal & Gulla Khel Pakistan

Response of Fodder Maize to Various Levels of Nitrogen and Phosphorus

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American Journal of Plant Sciences 2014年第15期5卷 2323-2329页

作者： Aziz Khan Fazal Munsif Kashif Akhtar Muhammad Zahir Afridi Zahoor Zahoor ahmad Shah Fahad Rizwan Ullah Faheem Ahmed Khan Mairaj din Crop Physiology and Production Center (CPPC) National Key Laboratory of Crop Genetic Improvement MOA Key Laboratory of Crop Eco-Physiology and Cultivation Huazhong Agricultural University Wuhan China Department of Agronomy The University of Agriculture Peshawar Pakistan Key Lab of Vegetable and Plant Diseases Hubei Province Wuhan China Key Laboratory of Animal Genetics Breeding and Reproduction Huazhong Agricultural University Wuhan China Key Laboratory of Horticulture Plant Biology (MOE) Huazhong Agricultural University Wuhan China MOA Key Laboratory of Crop Eco-Physiology and Farming System in the Mid-dle Reaches of the Yangtze River Hauzhong Agricultural University Wuhan China Moecular Biology Lab College of Plant Science and Technology Huazhong Agricultural University Wuhan China National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural University Wuhan China

Nitrogen (N) and Phosphorus (P) are of the most important and complex nutrients for the crop plants in particular for grain yield and quality. The field trials were laid out in randomized complete block design having three replications. Research trial plots were located at Agricultural Research Farm of Agricultural University Peshawar (Ameer Mohammad Khan Campus Mardan) during kharif season in 2012 to investigate the response of maize variety (Jalal) to three phosphorus rates (60, 90 and 120 kg·ha-1) and four nitrogen rates (90, 120, 150, 180 kg·ha-1) for agronomical traits. These traits investigated included number of plant per m2 (NP m2), plant height (PH), number of leaves plant-1 (NLP), leaf area plant-1·cm2 (LAP), fresh weight of plants kg·ha-1 (FW) and dry weight of plant kg·ha-1 (DW), were investigated. Results of the study showed that application of N @ 180 and P @ 120 kg·ha-1 significantly increased fodder yield of maize. The linear increase in biomass yield clearly indicated that N was a limiting nutrient factor and that N demand along with P has a positive response. At higher application rates, N fertilizer significantly increased biomass component, improved N uptake with increasing nitrogen use efficiency and decreased its losses to the environment and below plant zone. So this study showed that the phosphorus and nitrogen fertilizers have a positive effect on the fodder yield of maize.

关键词： Fodder Maize Nitrogen Phosphorus

Standardization of Famacha? system for natural parasites infected goat by comparing mucosa color

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Standardization of Famacha? system for natural parasites inf...