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Delineating the role of phytocompounds against anti-bacterial drug resistance–An update

BIOCELL 2021年第6期45卷 1465-1477页

作者： REKHA GAHTORI MOSLEH MOHAMMAD ABOMUGHAID NIDHI NEGI SARAVANAN KRISHNAN SUGAPRIYA DHANASEKARAN SOUMYA PANDIT KANU PRIYA dillip kumar bishi RAM PRASAD PIYUSH kumar GUPTA Department of Biotechnology Sir J.C.Bose Technical CampusKumaun UniversityNainitalIndia Department of Medical Laboratory Sciences University of BishaBishaSaudi Arabia Department of Chemistry Kumaun UniversityNainitalIndia Dhanvantari Nano Ayushadi Pvt. Ltd.ChennaiIndia Department of Medical Laboratory Sciences(Pathology) College of Applied Medical SciencesPrince Sattam Bin Abdulaziz UniversityRiyadhSaudi Arabia Department of Life Sciences School of Basic Sciences and ResearchSharda UniversityGreater NoidaIndia Department of Biotechnology Rama Devi Women’s UniversityBhubaneswarIndia Department of Botany Mahatma Gandhi Central UniversityMotihariIndia

Antibacterial resistance developed by bacteria due to the unlimited use of antibiotics has posed a challenge for human *** kind of problem is not limited to India only,but it is a global ***,many treatments and medicines for bacterial diseases have been ***,they possess some ***,the alternative medicine has been used to target the drug resistant mechanisms and such medicines have less side effects which is becoming *** products have traditionally or historically been of importance for the development of antibacterial agents and are also known to overcome bacterial drug resistance by directly targeting the drug resistance mechanisms in *** recent years,researchers have also focused on new drug discovery from plant-based *** have looked on various phytocompounds as antibacterial *** the current review,we report various classes of secondary metabolites such as phenolic compounds,flavonoids,alkaloids,saponins,terpenes,quinones,and some essential oils that have been used as an antibacterial *** addition,we also discuss several mechanisms behind bacterial multi-drug resistance that are used during bacterial pathogenesis.

关键词： Drug-resistance Phytocompounds Antibacterial Mechanisms Medicinal plants Natural products

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