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HVOF-sprayed HAp/S53P4 BG composite coatings on an AZ31 alloy for potential applications in temporary implants

Journal of Magnesium and Alloys 2024年第1期12卷 345-360页

作者： Carlos A.Poblano-Salas John Henao Astrid L.Giraldo-Betancur Paola Forero-Sossa diego German Espinosa-Arbelaez Jorge A.González-Sánchez Luis R.Dzib-Pérez Susana T.Estrada-Moo Idelfonso E.Pech-Pech CIATEQ A.C. Av.Manantiales 23-AParque Industrial Bernardo QuintanaEl MarquésQuerétaro 76246Mexico CONAHCYT-CIATEQ A.C. Av.Manantiales 23-AParque Industrial Bernardo QuintanaEl MarquésQuerétaro 76246Mexico CONAHCYT-Cinvestav Libramiento Norponiente#2000.Fraccionamiento Real de JuriquillaQuerétaro 76230Mexico Universidad Tecnológica de Querétaro Av.Pie de la Cuesta N°2501Querétaro 76148Mexico CIDESI Av.Playa Pie de la Cuesta No 702Col.San PabloQuerétaro 76125Mexico Center for Corrosion Research Autonomous University of CampecheAv.Héroe de Nacozari No.480P.C.24070San Francisco de CampecheCam.Mexico

Bioactive thermal spray coatings produced via high-velocity oxygen fuel spray(HVOF)from hydroxyapatite(HAp)and bioactive glasses(BG)have the potential to be employed on temporary implants due to the ability of both HAp and BG to dissolve and promote osseointegration,considering that both phases have different reaction and dissolution rates under in-vitro *** the present work,75%***-25%wt.S53P4 bioactive glass powders were HVOF-sprayed to obtain HAp/S53P4 BG composite coatings on a bioresorbable AZ31 *** study is focused on exploring the effect of the stand-off distance and fuel/oxygen ratio variation as HVOF parameters to obtain stable structural coatings and to establish their effect on the phases and microstructure produced in those *** characterization techniques,such as scanning electron microscopy,X-ray diffraction,and Fourier transform infrared spectroscopy,were employed to characterize relevant structural and microstructural properties of the composite *** results showed that thermal gradients during coating deposition must be managed to avoid delamination due to the high temperature achieved(max 550℃)and the differences in coefficients of thermal *** was also found that both spraying distance and oxygen/fuel ratio allowed to keep the hydroxyapatite as the main phase in the *** addition,in-vitro electrochemical studies were performed on the obtained HAp/S53P4 BG composite coatings and compared against the uncoated AZ31 *** results showed a significant decrease in hydrogen evolution(at least 98%)when the bioactive coating was applied on the Mg alloy during evaluation in simulated body fluid(SBF).

关键词： Coatings Composites Thermal spray Temporary implants Hydrogen evolution

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A comprehensive look at the psychoneuroimmunoendocrinology of spinal cord injury and its progression: mechanisms and clinical opportunities

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Military Medical Research 2024年第2期11卷 228-267页

作者： Miguel A.Ortega Oscar Fraile-Martinez Cielo García-Montero Sergio Haro Miguel Ángel Álvarez-Mon diego De Leon-Oliva Ana M.Gomez-Lahoz Jorge Monserrat Mar Atienza-Pérez David Díaz Elisa Lopez-Dolado Melchor Álvarez-Mon Department of Medicine and Medical Specialities University of Alcala28801 Alcala de HenaresSpain Ramón y Cajal Institute of Sanitary Research(IRYCIS) 28034 MadridSpain Department of Psychiatry and Mental Health Hospital Universitario Infanta Leonor28031 MadridSpain Service of Rehabilitation National Hospital for Paraplegic PatientsCarr.de la PeraledaS/N45004 ToledoSpain Immune System Diseases‑Rheumatology Service and Internal Medicine University Hospital Príncipe de Asturias(CIBEREHD)28806 Alcala de HenaresSpain

Spinal cord injury(SCI)is a devastating and disabling medical condition generally caused by a traumatic event(primary injury).This initial trauma is accompanied by a set of biological mechanisms directed to ameliorate neural damage but also exacerbate initial damage(secondary injury).The alterations that occur in the spinal cord have not only local but also systemic consequences and virtually all organs and tissues of the body incur important changes after SCI,explaining the progression and detrimental consequences related to this ***(PNIE)is a growing area of research aiming to integrate and explore the interactions among the different systems that compose the human organism,considering the mind and the body as a *** initial traumatic event and the consequent neurological disruption trigger immune,endocrine,and multisystem dysfunction,which in turn affect the patient's psyche and *** the present review,we will explore the most important local and systemic consequences of SCI from a PNIE perspective,defining the changes occurring in each system and how all these mechanisms are ***,potential clinical approaches derived from this knowledge will also be collectively presented with the aim to develop integrative therapies to maximize the clinical management of these patients.

关键词： Spinal cord injury(SCI) Psychoneuroimmunoendocrinology(PNIE) Secondary injury Immunoinflammatory dysfunction Gut microbiota Translational opportunities

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寻文化之根,叹汉语之美

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初中生 2024年第11期 4-17页

作者： Juan-diego Garcia 不详

主题语境:人与社会——人文历史,文化传承仓颉观天地万物而造字。一片甲骨,一些符号,让我们触摸到汉字的源头。正因为有了文字,我们才能从中窥见古人的智慧,感受中华民族几千年来的灿烂文化。联合国新闻部将中国二十四节气之“谷雨”(4... 详细信息

主题语境:人与社会——人文历史,文化传承仓颉观天地万物而造字。一片甲骨,一些符号,让我们触摸到汉字的源头。正因为有了文字,我们才能从中窥见古人的智慧,感受中华民族几千年来的灿烂文化。联合国新闻部将中国二十四节气之“谷雨”(4月20日)这一天定为联合国中文日。如今,越来越多来自世界各地的人们,为一部《论语》传递的“谦恭礼让”而折服,被汉语蕴藏的文化魅力所吸引。

关键词：文化传承二十四节气文化魅力天地万物汉语之美人文历史文化之根联合国

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超声辅助乙醇提取富硒金花葵花朵中的硒及抗氧化活性分析

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食品工业科技 2024年第16期45卷 201-208页

作者：张文开鲍征宇 diego Armando PINZON NUNEZ 邵玲玲徐峰张宏宇赵月华田欢中国地质大学(武汉)材料与化学学院湖北武汉430000 安康国硒源科技有限公司陕西安康725000 紫阳中地大硒科技有限公司陕西安康725000 西北大学地质学系陕西西安710000 武汉测绘研究院湖北武汉430000

为促进优质天然富硒植物资源的科学开发利用,本文选取富硒金花葵为研究对象,采用氢化物发生-原子荧光光谱法(Hydride Generation-Atomic Fluorescence Spectrometry,HG-AFS)检测不同植物器官样品中的硒含量,超声波辅助乙醇提取金花葵花... 详细信息

为促进优质天然富硒植物资源的科学开发利用,本文选取富硒金花葵为研究对象,采用氢化物发生-原子荧光光谱法(Hydride Generation-Atomic Fluorescence Spectrometry,HG-AFS)检测不同植物器官样品中的硒含量,超声波辅助乙醇提取金花葵花朵中的含硒有机活性组分并使用响应面法优化获得最佳提取工艺,同时对含硒提取物开展抗氧化活性研究。结果显示,金花葵各器官中硒含量从高到低依次为叶、果、花、根和茎,分别为21.99、14.29、12.93、10.90和10.23 mg/kg。响应面优化结果表明,含硒有机活性成分最佳提取参数为提取温度40℃、固液比1:60、提取时间40 min、超声功率350 W、乙醇浓度50%(V/V)和提取次数1次。在最佳提取参数下,硒的提取率为35.65%±0.65%。DPPH抗氧化活性测定结果显示,含硒有机活性成分的半抑制浓度(IC_(50))为0.048 mg/mL(硒元素浓度为0.79μg/mL),羟基自由基清除实验显示样品浓度为8 mg/mL时达到最大清除率97%,IC_(50)为0.56 mg/mL,还原力实验表明样品的还原能力随样品浓度的增大而增强。证明金花葵的含硒乙醇提取物具有良好的抗氧化能力。本研究可以为合理利用富硒金花葵和研发加工富硒农副作物提供一些理论依据。

关键词：金花葵硒含硒活性成分提取工艺优化响应面抗氧化活性

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Sensorial Evaluation and Physical Chemical Characterization of a Beverage Based on Whey and β-Glucans as a Potential Prevention of Nonalcoholic Steatohepatitis

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Food and Nutrition Sciences 2024年第8期15卷 770-789页

作者： Adriana hernandez Santana Andrea Jimena Valdés Alvarado Sandra Karina Espinoza Stephany Bernardeth Lanza Aguilar Food Science Department Zamorano Pan-American Agricultural School Tegucigalpa Honduras

Whey and B-glucans are functional food ingredients that contribute to the prevention of non-communicable diseases. The objective of the study was to develop a functional beverage based on whey, B-glucans, and blackberry concentrate for the prevention of nonalcoholic steatohepatitis, determining its sensory, physicochemical, and nutritional qualities. The following phases were developed: 1) formulation with 75%, 85%, and 90% whey and 25%, 15%, and 10% blackberry concentrate, with a fixed amount of 0.243 g β-glucans in 100 ml;2) microbiological analysis to ensure the safety of the beverage;3) sensory analysis with untrained panelists to assess the degree of preference (appearance, color, odor, flavor, viscosity, acidity, sweetness), and general acceptance, with a seven-point hedonic scale to rate the level of acceptability;4) physicochemical and nutritional characterization of the beverage with the highest acceptance. An experimental design using complete random blocks was employed. Data analysis was performed with variance (ANDEVA) and mean DUNCAN separation at a 95% confidence level, using SAS®. A correlation study was conducted on acceptance analysis. A nutritional label was developed for the control beverage and the treatment with the highest acceptance. The formulation with 75% whey, 25% blackberry concentrate, and 0.243 g of β-glucan obtained the highest acceptance, with flavor and sweetness being the attributes that contributed to its acceptance. Nutritionally, the beverage with 80 cal, would be considered fortified with fiber (2 g), free of cholesterol, sodium, and saturated fat, according to the Central American Technical Regulation on Nutritional Labeling (Version 67.01.60:10). It is recommended that the effect of this beverage be measured to determine the benefits.

关键词： Fatty Acids Fatty Liver Glucans Whey

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Austrian syndrome:Resurgence of an old and deadly triad

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Journal of Intensive Medicine 2024年第2期4卷 261-264页

作者： Kristian Rivera Dolors Viles Marta Zielonka Carlos Izurieta Tania Ramírez Martínez diego Menéndez Department of Cardiology University Hospital Arnau de VilanovaInstitut de Recerca Biomèdica de Lleida(IRBLleida)LleidaSpain

Introduction The Gram-positive bacterium,Streptococcus pneumoniae(***),often colonizes the nasopharynx;however,it is one of the major microorganisms that cause pneumonia and meningitis.[[1],[2],[3]]It presents several virulence factors,such as surface proteins and enzymes,pneumolysin toxin,and a polysaccharide capsule,which is mainly responsible for the immune response;the capsule also facilitates classification of the bacterium into several serotypes.[1,2]In vulnerable individuals,the bacterium may lead to the development of invasive pneumococcal disease(IPD),which is defined as an infection of normally sterile locations.

关键词： capsule sterile infection

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American tegumentary leishmaniasis mimicking myiasis and granulomatous vasculitis:A case report

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Asian Pacific Journal of Tropical Medicine 2024年第10期17卷 473-476,I0001,I0002页

作者： Victoria J Arrieta Gastón Morea Leticia M Tennerini María VSanchez Esteban S Lozano diego E Cargnelutti Instituto de Medicina y Biología Experimental de Cuyo(IMBECU) Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)Universidad Nacional de Cuyo(UNCuyo)MendozaArgentina Hospital Luis C.Lagomaggiore MendozaArgentina Facultad de Ciencias Médicas(FCM) Universidad Nacional de Cuyo(UNCuyo)MendozaArgentina

Rationale:American tegumentary leishmaniasis comprises cutaneous and mucocutaneous manifestations caused by parasitic infections by various Leishmania *** report details the clinical interventions for a patient with American tegumentary leishmaniasis in Mendoza,Argentina,a non-endemic *** concerns:A 43-year-old male was admitted to a tertiary care hospital in Mendoza,Argentina Republic with a history of progressive nasal discharge,septal perforation,facial pain,and *** treatment for presumed nasal myiasis and vasculitis with granulomatosis,symptoms ***:American tegumentary ***:Intravenous liposomal amphotericin ***:Follow-up at 30 days showed no recurrence of symptoms with a remarkable clinical improvement of the nasal ***:This case sheds light on the necessity of accurate identification for timely intervention and the need to recognize the diverse manifestations of American tegumentary leishmaniasis to avoid misdiagnosis.

关键词： Leishmania American tegumentary leishmaniasis Diagnosis methods Myasis Vasculitis and granulomatosis Case report

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A new implementation of FLEXPART with Enviro-HIRLAM meteorological input,and a case study during a heavy air pollution event

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Big Earth Data 2024年第2期8卷 397-434页

作者： Benjamin Foreback Alexander Mahura Petri Clusius Carlton Xavier Metin Baykara Putian Zhou Tuomo Nieminen Victoria Sinclair Veli-Matti Kerminen Tom V.Kokkonen Simo Hakala diego Aliaga Risto Makkonen Alexander Baklanov Roman Nuterman Men Xia Chenjie Hua Yongchun Liu Markku Kulmala Pauli Paasonen Michael Boy Aerosol and Haze Laboratory Beijing Advanced Innovation Center for Soft Matter Science and EngineeringBeijing University of Chemical TechnologyBeijingChina Institute for Atmospheric and Earth System Research/Physics Faculty of ScienceUniversity of HelsinkiHelsinkiFinland Division of Nuclear Physics Department of PhysicsLund UniversityLundSweden Swedish Meteorological and Hydrological Institute(SMHI) Research DepartmentUnit of Meteorology/Environment and ClimateNorrköpingSweden Climate and Marine Sciences Department Eurasia Institute of Earth SciencesIstanbul Technical UniversityIstanbulTurkey Department of Physics Faculty of ScienceUniversity of HelsinkiHelsinkiFinland Department of Meteorology(MISU)and Bolin Centre for Climate Research Stockholm UniversityStockholmSweden Climate System Research Unit Finnish Meteorological InstituteHelsinkiFinland Science and Innovation Department World Meteorological Organization(WMO)GenevaSwitzerland Niels Bohr Institute University of CopenhagenCopenhagenDenmark Joint International Research Laboratory of Atmospheric and Earth System Sciences School of Atmospheric SciencesNanjing UniversityNanjingChina School of Engineering Science Lappeenranta-Lahti University of Technology(LUT)LappeenrantaFinland Atmospheric Modelling Centre Lahti Lahti University CampusLahtiFinland

We integrated Enviro-HIRLAM(Environment-High Resolution Limited Area Model)meteorological output into FLEXPART(FLEXible PARTicle dispersion model).A FLEXPART simulation requires meteorological input from a numerical weather prediction(NWP)*** publicly available version of FLEXPART can utilize either ECMWF(European Centre for Medium-range Weather Forecasts)Integrated Forecast System(IFS)forecast or reanalysis NWP data,or NCEP(*** Center for Environmental Prediction)Global Forecast System(GFS)forecast or reanalysis NWP *** primary benefits of using Enviro-HIRLAM are that it runs at a higher resolution and accounts for aerosol effects in meteorological *** compared backward trajectories gener-ated with FLEXPART using Enviro-HIRLAM(both with and without aerosol effects)to trajectories generated using NCEP GFS and ECMWF IFS meteorological inputs,for a case study of a heavy haze event which occurred in Beijing,China in November *** found that results from FLEXPART were considerably different when using different meteorological *** aerosol effects were included in the NWP,there was a small but noticeable differ-ence in calculated ***,when looking at potential emission sensitivity instead of simply expressing trajectories as lines,additional information,which may have been missed when looking only at trajectories as lines,can be inferred.

关键词： Atmospheric and chemical transport modelling trajectory and particle dispersion modelling severe air pollution episode FLEXPART Enviro-HIRLAM

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竹构坦普尔酒店

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世界建筑导报 2024年第1期39卷 118-120,F0003页

作者： Pacha Mother(摄影) Adrian hernandez(摄影) 不详

Arquitectura Mixta为“女人岛秘密印象”酒店开发的结构受到该项目独特的自然和地理环境的启发。该酒店位于墨西哥女人岛南端,靠近卡拉风自然礁公园,项目两侧可欣赏加勒比海全景,是墨西哥唯一可以观赏加勒比海日落的地方之一。Arquitec... 详细信息

Arquitectura Mixta为“女人岛秘密印象”酒店开发的结构受到该项目独特的自然和地理环境的启发。该酒店位于墨西哥女人岛南端,靠近卡拉风自然礁公园,项目两侧可欣赏加勒比海全景,是墨西哥唯一可以观赏加勒比海日落的地方之一。Arquitectura Mixta设计的4座竹结构彰显了墨西哥加勒比海的鲜艳色彩及其繁茂的生活。尽管它们的形状和规模不同,但这些结构在它们之间创造了一种对话,使它们成为单一概念和单一家庭的一部分。

关键词：竹结构坦普尔地理环境加勒比海酒店墨西哥 quite Mix

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Unusual Case of Unilateral Neonatal Eyeball Luxation: A Case Report

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Open Journal of Ophthalmology 2024年第1期14卷 69-75页

作者： Abdullah S. Alghamdi Muhammed S. Alrajeh Ahmad S. Alsalem Silvana Schellini Azzah Maktabi Amal Alhumaidan diego Strianese Prince Sultan Military Medical City Riyadh Saudi Arabia King Abdulaziz Medical City Riyadh Saudi Arabia King Khalid Eye Specialist Hospital Riyadh Saudi Arabia University of Naples Federico II Naples Italy

The newborn infant presented with severe proptosis. Data on clinical history, presentation, photos, radiological imaging, and laboratory results were presented. A literature review was conducted for the case and relevant treatment modalities. The surgical technique and the outcome were also discussed. The mass was present since birth in a full term neonate, causing complete globe dislocation of the left eye. Imaging showed a large cystic retro-bulbar mass completely occupying the orbital cavity and causing anterior dislocation of the left globe. Surgical excision of the tumor was carried out with globe preservation and Histopathology examination confirmed the diagnosis of optic nerve glioma. This was an atypical presentation of an optic nerve glioma causing globe dislocation in a neonate. The resection of such a large orbital tumor made globe preservation possible and resulted in an excellent cosmetic outcome. .

关键词： Neonatal Proptosis Optic Nerve Glioma Globe Dislocation Globe Preservation Cosmetic Surgery

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