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Predictive performance of the variation rate of the driving pressure on the outcome of invasive mechanical ventilation in patients with acute respiratory distress syndrome

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Chinese Journal of Traumatology 2024年第2期27卷 107-113页

作者： Hui-Dan Jing Jun-Ying Tian Wei Li Bing-Ling He Hong-Chao Li Fu-xia Jian cui Shang Feng Shen Department of Intensive Care Unit The Affiliated Hospital of Guizhou Medical UniversityGuiyang 550004China Department of Intensive Care Unit Army Medical Center of PLAChongqing400042China College of Foreign Languges Chongqing Medical UniversityChongqing400016China

Purpose:To assess the value of the driving pressure variation rate(ΔP%)in predicting the outcome of weaning from invasive mechanical ventilation in patients with acute respiratory distress ***:In this case-control study,a total of 35 patients with moderate-severe acute respiratory distress syndrome were admitted to the intensive care unit between January 2022 and December 2022 and received invasive mechanical ventilation for at least 48 h were *** were divided into successful weaning group and failed weaning group depending on whether they could be removed from ventilator support within 14 *** measures including driving pressure,PaO2:FiO2,and positive end-expiratory pressure,*** assessed every 24 h from day 0 to day 14 until successful weaning was *** measurement data of non-normal distribution were presented as median(Q1,Q3),and the differences between groups were compared by Wilcoxon rank sum *** categorical data use the Chi-square test or Fisher's exact test to *** predictive value ofΔP%in predicting the outcome of weaning from the ventilator was analyzed using receiver operating characteristic ***:Of the total 35 patients included in the study,17 were successful vs.18 failed in weaning from a ventilator after 14 days of mechanical *** cut-off values of the medianΔP%measured by Operator 1 *** 2 in the first 4 days were≥4.17%and 4.55%,respectively(pdifference in mechanical ventilation duration between the successful weaning group and the failure weaning group(8(6,13)vs.12(7.5,17.3),p=0.043).The incidence of ventilator-associated pneumonia in the successful weaning group was significantly lower than in the failed weaning group(0.2‰vs.2.3‰,p=0.001).There was a significant difference noted between these

关键词： Driving pressure Driving pressure variation rate Acute respiratory distress syndrome Mechanical ventilation

被扭曲的史观与史实——评大英博物馆展览《中国的隐秘世纪(1796-1912)》

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近代史研究 2024年第2期 4-12,M0003页

作者：夏春涛崔志海中国社会科学院近代史研究所

在花旗银行赞助下,大英博物馆数月前推出展览《中国的隐秘世纪(1796-1912)》和同名书籍,在西方引起不小关注。然而,该展览和同名书籍持错误的历史观,回避甚或美化罪恶的帝国主义侵华史,片面强调西方冲击对中国产生的所谓“正面”作用,... 详细信息

在花旗银行赞助下,大英博物馆数月前推出展览《中国的隐秘世纪(1796-1912)》和同名书籍,在西方引起不小关注。然而,该展览和同名书籍持错误的历史观,回避甚或美化罪恶的帝国主义侵华史,片面强调西方冲击对中国产生的所谓“正面”作用,同时深受“新清史”影响,在涉及中国边疆和民族问题时,曲解中华民族多元一体格局和中华文明统一性的突出特性,多有荒谬之言。在论及具体史实时,也多有常识性错误。史观与史实被严重扭曲,该展览及书籍对这段历史的解读自然也就不可靠、不可信。

关键词：史观史实大英博物馆 19世纪中国《晚清百态》

头胎儿童的同胞接纳与人际信任、心理韧性的关系

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中国心理卫生杂志 2024年第8期38卷 699-705页

作者：崔诣晨夏琪张丽琴广东技术师范大学教育科学学院广州510665 南京大学社会学院南京210023 扬州高等职业技术学校江苏扬州225003 南京晓庄学院学报编辑部南京210017

目的:考察头胎儿童的同胞接纳与人际信任、心理韧性的关系。方法:选取715名12~14岁头胎儿童,采用同胞接纳度量表(SAS)、儿童普遍信任量表(CGTS)、心理韧性量表(CD-RISC)和情绪调节问卷(ERQ)分别评估同胞接纳与人际信任、心理韧性、情绪... 详细信息

目的:考察头胎儿童的同胞接纳与人际信任、心理韧性的关系。方法:选取715名12~14岁头胎儿童,采用同胞接纳度量表(SAS)、儿童普遍信任量表(CGTS)、心理韧性量表(CD-RISC)和情绪调节问卷(ERQ)分别评估同胞接纳与人际信任、心理韧性、情绪调节策略,采用多重线性回归分析探讨各变量之间的关系。结果:多重线性回归分析显示,头胎儿童CGTS得分通过心理韧性得分间接关联同胞接纳得分(β=0.34,P<0.01);ERQ认知重评得分在人际信任得分的作用下与心理韧性得分负向关联(β=-0.23,P<0.001),ERQ表达抑制得分在心理韧性得分作用下与同胞接纳得分正向关联(β=0.29,P<0.001)。结论:头胎儿童的同胞接纳在心理韧性的中介作用下与人际信任产生间接关联;情绪调节策略在心理韧性的作用下间接影响头胎儿童的人际信任与同胞接纳。

关键词：头胎儿童同胞接纳人际信任心理韧性情绪调节策略

不同微生物制剂对土壤中结合态Zn稳定性的影响

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上海交通大学学报（农业科学版） 2017年第3期32卷 70-75,89页

作者：张宗迪崔夏倩杨延斌奥岩松上海交通大学农业与生物学院上海200240

为了探索修复Zn污染土壤的有效途径,在4种含Zn量分别为97.4、300、600、900mg/kg的土壤中分别添加木霉菌(40g/kg)和AB菌(40mL/kg)后种植苋菜。测定结果显示,添加木霉的4种土壤中有效态Zn含量比对照分别减少了1.75%、13.9%、19.47%、14.8... 详细信息

为了探索修复Zn污染土壤的有效途径,在4种含Zn量分别为97.4、300、600、900mg/kg的土壤中分别添加木霉菌(40g/kg)和AB菌(40mL/kg)后种植苋菜。测定结果显示,添加木霉的4种土壤中有效态Zn含量比对照分别减少了1.75%、13.9%、19.47%、14.86%,苋菜中Zn的富集量比对照分别提高了56.4%、37.4%、25.23%和47.06%;添加AB菌的4种土壤中有效态Zn含量比对照分别提高了15.79%、31.02%、26.55%和17.75%,苋菜中Zn的富集量比对照分别提高了47.73%、33.8%、29.99%、41.17%。这些结果表明AB菌和木霉菌对土壤中有效态Zn含量的影响存在差异,不同微生物菌剂对土壤重金属有效态的影响不同,选择合适的微生物菌剂,对重金属污染土壤的微生物修复具有重要意义。

关键词：木霉 AB菌 Zn污染土壤生物修复

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新媒体时代高校网络思政教育探析

广州城市职业学院学报 2024年第1期18卷 54-57页

作者：崔霞广东轻工职业技术学院大学生心理健康教育与咨询中心广东广州510300

新媒体时代,高校网络思政教育面临理论脱离现实削弱思政教育心理认同感、“单一事件”处理不当影响受教育主体三观形成、传统教学方式难以提供情绪价值、第二课堂难以实现行为养成、网络舆情误引导不力造成学生信任危机等挑战。应对这... 详细信息

新媒体时代,高校网络思政教育面临理论脱离现实削弱思政教育心理认同感、“单一事件”处理不当影响受教育主体三观形成、传统教学方式难以提供情绪价值、第二课堂难以实现行为养成、网络舆情误引导不力造成学生信任危机等挑战。应对这些挑战,提出六个应对策略:一是学用结合,增强网络思政教育的实用性;二是直面社会热点问题,淡化“单一事件”负面影响;三是增强新媒体思维,提升第一课堂吸引力;四是构建第二课堂新媒体阵地,提高师生互动性;五是加快建设网络舆情引导处理机制;六是坚持网络思政教育教师引领者地位。

关键词：新媒体时代高校网络思政教育

An overview of prostate diseases and their characteristics specific to Asian men

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Asian Journal of Andrology 2012年第3期14卷 458-464,I0008页

作者： Shu-Jie xia di cui Qi Jiang Department of Urology The First People's Hospital Affiliated to Shanghai Jiao Tong UniversityShanghai 200080China

In this paper, we reviewed the features of common prostate diseases, such as benign prostatic hyperplasia （BPH）, prostate cancer （PCa） and chronic prostatitis （CP） that are specific to Asian men. Compared to the Westerners, Asians exhibit particular characteristics of prostate diseases. Through summarizing the epidemiology, symptomatology, diagnostics and therapeutics of these diseases, we find that Asians have a lower incidence of PCa than whites, but the incidences of BPH and CP are similar. Asian men with CP often suffer from fewer disease sites, but have a higher frequency of pain during urination rather than after sexual climax. Prostate-specific antigen （PSA） is a widely used marker for the diagnosis of PCa in both Asian and Western countries. Although the PSA level may be lower in Asians, the threshold used is based on whites. After reviewing the treatments available for these diseases, we did not find a fundamental difference between Asians and whites. Furthermore, the selection for the most appropriate treatment based on the individual needs of patients remains a challenge to urologists in Asia. After considering the traits of prostate diseases that are specific to Asian men, we hope to pave the way for the development of specific diagnostic and therapeutic strategies targeted specifically to Asian men.

关键词： Asians benign prostatic hyperplasia chronic prostatitis prostate cancer

Screening antimicrobial peptides and probiotics using multiple deep learning and directed evolution strategies

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Acta Pharmaceutica Sinica B 2024年第8期14卷 3476-3492页

作者： Yu Zhang Li-Hua Liu Bo Xu Zhiqian Zhang Min Yang Yiyang He Jingjing Chen Yang Zhang Yucheng Hu Xipeng Chen Zitong Sun Qijun Ge Song Wu Wei Lei Kaizheng Li Hua cui Gangzhu Yang Xuemei Zhao Man Wang Jiaqi xia Zhen Cao Ao Jiang Yi-Rui Wu Tidetron Bioworks Technology(Guangzhou)Co. Ltd.Guangzhou Qianxiang Bioworks Co.Ltd.Guangzhou 510000China Biology Department and Institute of Marine Sciences College of ScienceShantou UniversityShantou 515063China School of Basic Medical Sciences Hubei University of Science and TechnologyXianning 437100China School of Education Jianghan UniversityWuhan 430056China Yeasen Biotechnology(Shanghai)Co. Ltd.Shanghai 200000China School of Basic Medicine Jiamusi UniversityJiamusi 154000China

Owing to their limited accuracy and narrow applicability,current antimicrobial peptide(AMP)prediction models face obstacles in industrial *** address these limitations,we developed and improved an AMP prediction model using Comparing and Optimizing Multiple DEep Learning(COMDEL)algorithms,coupled with high-throughput AMP screening method,finally reaching an accuracy of 94.8%in test and 88%in experiment verification,surpassing other state-of-the-art *** conjunction with COMDEL,we employed the phage-assisted evolution method to screen Sortase in vivo and developed a cell-free AMP synthesis system in vitro,ultimately increasing AMPs yields to a range of 0.5-2.1 g/L within ***,by multi-omics analysis using COMDEL,we identified Lactobacillus plantarum as the most promising candidate for AMP generation among 35 edible *** this,we developed a microdroplet sorting approach and successfully screened three *** mutants,each showing a twofold increase in antimicrobial ability,underscoring their substantial industrial application values.

关键词： Antimicrobial peptide Deep learning Cell-free synthesis Probiotics L.plantarum

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混杂纤维高强轻骨料混凝土单轴受压试验研究

材料导报 2024年第2期38卷 126-131页

作者：崔涛涛宁宝宽郜殿伟夏旭东沈阳工业大学建筑与土木工程学院沈阳110870

为了改善高强轻骨料混凝土(HSLC)的脆性破坏特征,采用钢纤维(SF)和聚丙烯纤维(PF)对HSLC进行增强,通过单轴受压试验研究两种纤维对HSLC单轴受压性能的影响。结果表明:SF和PF的体积掺量分别为2.0%和0.2%时具有最优的混杂效应,应力-应变... 详细信息

为了改善高强轻骨料混凝土(HSLC)的脆性破坏特征,采用钢纤维(SF)和聚丙烯纤维(PF)对HSLC进行增强,通过单轴受压试验研究两种纤维对HSLC单轴受压性能的影响。结果表明:SF和PF的体积掺量分别为2.0%和0.2%时具有最优的混杂效应,应力-应变曲线拐点处应力和收敛点处应变较单掺SF时分别提高了10.0%和56.5%,较单掺PF时分别提高了99.1%和150%;混杂纤维使HSLC的峰值应力、峰值应变和弹性模量最高分别提升了19.0%、1.20%和16.9%。最后,基于试验数据,提出了考虑两种纤维混杂效应的峰值应力、峰值应变和弹性模量的计算公式,建立了双参数混杂纤维增强HSLC的单轴受压本构模型,并且其与试验曲线吻合较好。该研究结果可为纤维增强HSLC的结构设计提供理论参考。

关键词：混杂纤维高强轻骨料混凝土应力-应变曲线混杂效应本构模型

Corrosion Resistance Enhancement of Pure Zirconium in Various Environments via Microstructure Tailoring

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稀有金属材料与工程 2024年第8期53卷 2109-2122页

作者： xia Chaoqun Li Ke cui Ziyao Song Tianshuo Wu Xinyu Liu Shuguang Zouxianrui Zhang Shiliang Yang Tai Li Qiang Tianjin Key Laboratory of Materials Laminating Fabrication and Interface Control Technology School of Materials Science and EngineeringHebei University of TechnologyTianjin 300401China Industrial Technology Research Institute Hebei University of TechnologyTianjin 300401China Engineering Research Center for Electrophysical Apparatus and Application Technology Beijing Research Institute of Automation for Machinery Industry Co.LtdBeijing 100120China

The corrosion properties of pure zirconium(Zr)with different grain sizes in acid,alkali,and salt environments were *** microstructures of pure Zr were observed by optical microscope,X-ray diffractometer,and electron backscattered diffraction *** corrosion resistance of pure Zr was analyzed by electrochemical corrosion test and immersion *** show that pure Zr with grain size of 4–32μm can be obtained after annealing at 800°C for different durations,and the relationship between grain size and annealing duration is D^(3)−D_(0)^(3)=*** electrochemical corrosion and immersion corrosion test results show that the pure Zr with grain size of about 24μm(annealing at 800°C for 20 h)possesses the optimal corrosion resistance.

关键词： pure zirconium grain size various environments corrosion resistance