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陕西省铜川市HIV感染者/AIDS患者接受抗病毒治疗后生存分析及预测模型构建

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中国热带医学 2024年第5期24卷 598-602页

作者：马龙邓文升时洁巩娟芳赵宇鑫陈小宁封小洁铜川市疾病预防控制中心陕西铜川727031 陕西省地方病防治研究所陕西西安710003

目的分析陕西省铜川市HIV感染者/AIDS患者(HIV/AIDS)接受抗病毒治疗后生存影响因素,为铜川市实行精准化治疗提供科学依据。方法采用回顾性队列研究,收集2005—2023年铜川市接受抗病毒治疗的HIV/AIDS一般人口学特征和生存相关信息,利用... 详细信息

目的分析陕西省铜川市HIV感染者/AIDS患者(HIV/AIDS)接受抗病毒治疗后生存影响因素,为铜川市实行精准化治疗提供科学依据。方法采用回顾性队列研究,收集2005—2023年铜川市接受抗病毒治疗的HIV/AIDS一般人口学特征和生存相关信息,利用寿命表分析累计生存率,Cox回归模型分析生存影响因素,构建列线图模型,预测抗病毒治疗预后。结果410例HIV/AIDS接受抗病毒治疗后生存时间最短观察期0个月,最长222个月,M(P_(25),P_(75))为71(64,106)个月;随访362例,艾滋病相关死亡39例。抗病毒治疗1年、5年和10年累计生存率分别为96.2%、91.3%和83.0%;多因素Cox分析显示抗病毒治疗后,大专以上文化程度(HR=0.349,95%CI:0.159~0.769)和无临床症状(HR=0.357,95%CI:0.178~0.715)的HIV/AIDS死亡风险较低,CD4细胞计数<200 cells/μL组(HR=9.383,95%CI:2.879~30.578)死亡风险较高。基于以上3个影响因素构建列线图模型,内部验证显示模型区分度C-index=0.859(95%CI:0.762~0.956),校准曲线提示模型一致性良好,具有较好的预测能力。结论铜川市应扩大艾滋病防治健康教育,加强HIV监测,在HIV/AIDS中进行抗病毒治疗依从性教育,及时进行CD4细胞计数检测,利用构建的列线图模型辅助临床进行精准化诊疗。

关键词：艾滋病抗病毒治疗生存分析预测模型

Ab Initio Studies on MCH2（OH） and CH3OM（M=H, -, Li, Na）

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Chemical Research in Chinese Universities 2000年第2期 136-140页

作者： WANG Yigui,SUN Changjun,BIAN wensheng ,deng Conghao

MCH 2(OH) and CH 3OM(M=-, Li, Na) were calculated by means of ab initio method at the MP2/631+G* level. The results show that the metals have the ability to localize charge on O in CH 3OM(M= Li, Na). MCH 2(OH)(M=Li, Na) has four possible structures, among which carbonoxygenbridged structure 1 is the most stable and observable kinetically. For MCH 2(OH)(M=Li, Na), the existence of the metal increases the rigidity of the carbon configuration. This may be the reason why MCH 2(OR)(M=Li, Na) is widely used in stereoselective syntheses.

关键词： Carbanion Carbenoid Ether Lithium Sodium

Genome-Wide Association Study of Cooked Rice Textural Attributes and Starch Physicochemical Properties in indica Rice

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Rice science 2024年第3期31卷 300-316,I0018-I0041页

作者： deng Bowen ZHANG Yanni ZHANG Fan WANG wensheng XU Jianlong ZHANG Yu BAO Jinsong Institute of Nuclear Agricultural Sciences Key Laboratory of Nuclear Agricultural Sciences of Ministry of Agriculture and Zhejiang ProvinceCollege of Agriculture and BiotechnologyZhejiang UniversityHangzhou 310058China Hainan Institute Zhejiang UniversitySanya 572025China Institute of Crop Sciences Chinese Academy of Agricultural SciencesBeijing 100081China

Rice cooking and eating qualities(CEQ)are mainly determined by cooked rice textural parameters and starch physicochemical ***,the genetic bases of grain texture and starch properties in rice have not been fully *** conducted a genome-wide association study for apparent amylose content(AAC),starch pasting viscosities,and cooked rice textural parameters using 279 indica rice accessions from the 3000 Rice Genome *** identified 26 QTLs in the whole population and detected single nucleotide polymorphisms(SNPs)with the lowest P-value at the Waxy(Wx)locus for all traits except pasting temperature and ***,we detected significant SNPs at the SUBSTANDARD STARCH GRAIN6(SSG6)locus for AAC,setback(SB),hardness,adhesiveness,chewiness(CHEW),gumminess(GUM),and *** subsequently divided the population using a SNP adjacent to the Waxy locus,and identified 23 QTLs and 12 QTLs in two sub-panels,WxT and WxA,*** these sub-panels,SSG6 was also identified to be associated with pasting parameters,including peak viscosity,hot paste viscosity,cold paste viscosity,and consistency ***,a candidate gene encoding monosaccharide transporter 5(OsMST5)was identified to be associated with AAC,breakdown,SB,CHEW,and *** total,39 QTLs were co-localized with known genes or previously reported *** identified genes and QTLs provide valuable information for genetic manipulation to improve rice CEQ.

关键词： cooking and eating quality genome-wide association study rice Waxy gene

Amphipathic Janus Nanofibers Aerogel for Efficient Solar Steam Generation

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Energy & Environmental Materials 2024年第4期7卷 422-432页

作者： Rui Wang Jinshuo deng Ping Wu Qianli Ma Xiangting Dong wensheng Yu Guixia Liu Jinxian Wang Lei Liu Chongqing Research Institute Changchun University of Science and Technology Key Laboratory of Applied Chemistry and Nanotechnology at Universities of Jilin Province Changchun University of Science and Technology

Solar steam generation is a promising water purification technology due to its low-cost and environmentally friendly applications in water purification and ***,hydrophilic or hydrophobic materials alone are insufficient in achieving necessary characteristics for constructing highquality solar steam generators with good comprehensive properties.

关键词： aerogels electrospinning photothermal materials solar desalination solar steam generation

命题逻辑演算方法在多时相遥感影像专题解译中的应用

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武汉大学学报（信息科学版） 2005年第2期30卷 170-173页

作者：邓文胜关泽群秦昆武汉大学遥感信息工程学院

介绍了命题逻辑演算方法。以武汉地区1993年和2002年的LandsatTM数据为例,应用该方法对近10年武汉城镇建筑的覆盖变化进行了试验,证明了该方法用于土地利用动态变化的可行性。

关键词：命题逻辑演算遥感影像建筑覆盖变化

ENERGIES AND WIDTHS OF HIGH TRIPLY EXCITED STATES OF LITHIUM

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原子与分子物理学报 1998年第S1期15卷 13-14页

作者： Gou Bingcong deng wenshengBeijing Institute of Technology Beijing 100081Kwong T.ChungDepartment of Physics, North Carolina State University, Raleigh, NC27695, USA

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浅谈港口企业如何加强设备管理工作

港口装卸 1999年第1期 32-33页

作者：邓文胜铜陵港务管理局铜陵244000

加强企业设备管理工作旧建立现代企业制度、推进企业改革的需要.建立现代企业制度的四个基本特征之一就是管理科学,而设备管理是现代企业管理的重要组成部分.因此,建立起适应市场经济要求的科学的设备管理体系,对于建立现代企业制度具... 详细信息

加强企业设备管理工作旧建立现代企业制度、推进企业改革的需要.建立现代企业制度的四个基本特征之一就是管理科学,而设备管理是现代企业管理的重要组成部分.因此,建立起适应市场经济要求的科学的设备管理体系,对于建立现代企业制度具有十分重要的意义.

关键词：港口企业设备管理港口机械

Oriented mesoporous nanofibers show nature's wisdom

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National Science Review 2024年第6期11卷 90-91页

作者： Yonghui deng Department of Chemistry State Key Laboratory of Molecular Engineering of Polymers Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials Collaborative Innovation Center of Chemistry for Energy Material (iChEM) Fudan University State Key Lab of Transducer Technology Shanghai Institute of Microsystem and Information Technology Chinese Academy of Sciences

Electrodes assembled with conventional nanoparticulate materials in electrochemical energy devices usually have a random and torturous porous system. To meet ever-increasing demands for higher volumetric energy density at packagelevel, packing more active materials in a limited volume becomes increasingly difficult since transportation of reactants(e.g. electrolyte) and charges through high-tortuosity channels/pathways in thick electrodes meets large impedance[1].

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Filamin A represses RNA polymerase Ⅲ gene transcription

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Filamin A represses RNA polymerase Ⅲ gene transcription