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Expert consensus on irrigation and intracanal medication in root canal therapy

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International Journal of Oral Science 2024年第1期16卷 26-35页

作者： Xiaoying Zou Xin Zheng Yuhong Liang Chengfei Zhang Bing Fan Jingping Liang Junqi ling Zhuan Bian Qing Yu Benxiang Hou Zhi Chen Xi Wei Lihong Qiu Wenxia Chen Wenxi He Xin Xu Liuyan Meng Chen Zhang Liming Chen Shuli deng Yayan Lei Xiaoli Xie Xiaoyan Wang Jinhua Yu Jin Zhao Song Shen Xuedong Zhou Lin Yue Department of Cariology and Endodontology Peking University School and Hospital of Stomatology&National Center of Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Laboratory for Digital and Material Technology of Stomatology&Beijing Key Laboratory of Digital Stomatology&Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health&NMPA Key Laboratory for Dental MaterialsBeijingChina Center of Stomatology Peking University HospitalBeijingChina State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&West china Hospital of Stomatology Sichuan UniversityChengduChina Department of Emergency Peking University School and Hospital of Stomatology&National Center of Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Laboratory for Digital and Material Technology of Stomatology&Beijing Key Laboratory of Digital Stomatology&Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health&NMPA Key Laboratory for Dental MaterialsBeijingChina Restorative Dental Sciences EndodonticsFaculty of DentistryThe University of Hong KongPok Fu LamHong Kong SARChina State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration Key Laboratory of Oral Biomedicine Ministry of EducationHubei Key Laboratory of StomatologySchool&Hospital of StomatologyWuhan UniversityWuhanChina Department of Endodontics Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineCollege of StomatologyShanghai Jiao Tong UniversityNational Clinical Research Center for Oral DiseasesNational Center for StomatologyShanghai Key Laboratory of StomatologyShanghaiChina Department of Operative Dentistry and Endodontics Hospital of StomatologyGuanghua School of StomatologySun Yat-Sen University&Guangdong Provincial Key Laboratory of StomatologyGuangzhouChina State Key Laboratory of Oral&Maxillofacial Reconstruction and R

chemical cleaning and disinfection are crucial steps for eliminating infection in root canal treatment. However, irrigant selection or irrigation procedures are far from clear. The vapor lock effect in the apical region has yet to be solved, impeding irrigation efficacy and resulting in residual infections and compromised treatment outcomes.

关键词： treatment irrigation Expert

Establishment of an oligoasthenospermia mouse model based on TAp73.gene suppression

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Animal Models and Experimental Medicine 2021年第4期4卷 351-358页

作者： Hong-Juan Liu Meng-Yun deng Yan-Yan Zhu De-ling Wu Xiao-Hui {2. Li Li Lei Wang Fei Xu {2.-Sheng Wang School of Integrated Traditional chinese and Western Medicine Anhui University of Chinese MedicineHefeiChina Anhui Province Key Laboratory of chinese Medical Formula School of PharmacyAnhui University of Chinese MedicineHefeiChina

Background:Oligoasthenospermia is one of the main causes of male *** usually use chemical drugs to directly damage germ cells to prepare oligoasthenospermia models,which disregards the adhesion and migration between spermatogenic cells and Sertoli ***73.is a critical regulator of the adhesin of germ cell;thus,we sought to explore a novel oligoasthenospermia model based on TAp73.gene ***:Mice in the Pifithrin-αgroup were injected intraperitoneally with 2.5 mg/kg Pifithrin-α(TAp73.inhibitor)daily for 3. consecutive *** hormone levels and epididymal sperm quality,as well as the network morphology of Sertoli cells were ***:Sperm density,motility,and the relative protein and mRNA expression of TAp73.and Nectin 2.were obviously decreased in the Pifithrin-αgroup compared with the normal control *** significant distinction was observed in the relative mRNA and protein expression of ***,the tight junctions(TJs)and api-cal ectoplasmic specialization(ES)were destroyed in the Pifithrin-α***:The above results indicate that we successfully established a new oli-goasthenospermia mouse *** study provides a foundation for further explo-ration of the roles of TAp73.genes during spermatogenesis and provides new research objects for further oligospermia research and future drug discovery.

关键词： ectoplasmic specialization Nectin 2 oligoasthenospermia TAp73 ZO-1

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紫藤根及含紫藤根经验方的初步药效研究

江西化工 2024年第1期40卷 78-83页

作者：罗健菱胡家震唐娟邓斌马彬焰邰通芝胡成刚贵州中医药大学贵州贵阳550025

目的:探讨紫藤根及含紫藤根经验方的抗炎、镇痛作用及其药效动力学规律。方法:通过小鼠棉球肉芽肿炎症实验研究紫藤根及含紫藤根经验方的慢性增生性抗炎作用,同时通过小鼠扭体实验探索紫藤根及含紫藤根习用经验方的镇痛作用。结果:紫藤... 详细信息

目的:探讨紫藤根及含紫藤根经验方的抗炎、镇痛作用及其药效动力学规律。方法:通过小鼠棉球肉芽肿炎症实验研究紫藤根及含紫藤根经验方的慢性增生性抗炎作用,同时通过小鼠扭体实验探索紫藤根及含紫藤根习用经验方的镇痛作用。结果:紫藤根及含紫藤根经验方3.剂量组均能不同程度地抑制肉芽的生长,对于棉球肉芽肿所引起的慢性炎症有抑制作用;同时,此方各剂量组均有极显著的镇痛作用。结论:验证了紫藤根及含紫藤根经验方的抗炎、镇痛效果,同时诠释了其经验方所占配伍比例偏少会使整个经验方的抗炎、镇痛效果更好,此研究能为紫藤根的质量标准与临床应用提供参考。

关键词：紫藤根及含紫藤根经验方抗炎作用镇痛作用药理研究

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乙烯裂解装置混合石脑油原料的模拟与优化

石化技术与应用 2024年第1期42卷 31-34,51页

作者：陈梦君崔登科刘亭亭赵涛才力毛玲娟童佳馨浙江石油化工有限公司研究院浙江舟山316000 浙江省绿色石化技术创新中心浙江宁波315048 华北电力大学能源动力与机械工程学院北京102208

利用SPYRO流程模拟软件建立了140万t/a乙烯裂解装置的裂解炉机理模型,考察了混合石脑油原料掺炼芳烃抽余油,对乙烯裂解装置乙烯收率及运行周期的影响。结果表明:该模型可应用于乙烯裂解装置的原料模拟与优化;偏重混合石脑油或偏轻混合... 详细信息

利用SPYRO流程模拟软件建立了140万t/a乙烯裂解装置的裂解炉机理模型,考察了混合石脑油原料掺炼芳烃抽余油,对乙烯裂解装置乙烯收率及运行周期的影响。结果表明:该模型可应用于乙烯裂解装置的原料模拟与优化;偏重混合石脑油或偏轻混合石脑油中,掺炼芳烃抽余油后,对乙烯收率影响不大;当m(偏重混合石脑油)/m(芳烃抽余油)为1∶1时,原料在炉管内停留时间最短,预计1个运行周期内,较偏重混合石脑油单独裂解的工况,可多运行2.d,1 a预计多运行8 d;而偏轻石脑油原料则无需掺炼芳烃抽余油。

关键词：乙烯裂解裂解炉模拟优化混合石脑油芳烃抽余油

SynBioEcoli： a comprehensive metabolism network of engineered E. coil in three dimensional visualization

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Frontiers of Electrical and Electronic Engineering in china 2017年第1期5卷 99-104页

作者： Weizhong Tu Shaozhen Ding ling Wu Zhe deng Hui Zhu Xiao{2. Xu Chen Lin Chaonan Ye Minlu Han Mengna Zhao Juan Liu Zixin deng Junni Chen Dong-Qing Wei Qian-Nan Hu Tianjin Institute of Industrial Biotechnology Chinese Academy of Sciences Tianjin 300308 China Wuhan LifeSynther Cooperation Limited Wuhan 430078 China Ministry of Education Key Laboratory of Combinatorial Biosynthesis and Drug Discovery and School of Pharmaceutical Sciences Wuhan University Wuhan 430071 China State Key Laboratory of Software Engineering and School of Computer Sciences Wuhan University Wuhan 430072 China State Key Laboratory of Microbial Metabolism Shanghai Jiao Tong University Shanghai 200240 China

Background： A comprehensive metabolism network of engineered E. coli is very important in systems biology and metabolomics studies. Many tools focus on two-dimensional space to display pathways in metabolic network. However, the usage of three-dimensional visualization may help to understand better the intricate topology of metabolic and regulatory networks. Methods： We manually curated large amount of experimental data （including pathways, reactions and metabolites） from literature related with different types of engineered E. coli and then utilized a novel technology of three dimensional visualization to develop a comprehensive metabolic network named SynBioEcoll. Results： SynBioEoli contains 740 biosynthetic pathways, 3.889 metabolic reactions, 2.2.5 chemical compounds manually curated from about 11,000 metabolism publications related with different types of engineered E. coil Furthermore, SynBioEcoli integrates with various informatics techniques. Conclusions： SynBioEcoli could be regarded as a comprehensive knowledgebase of engineered E. coli and represents the next generation cellular metabolism network visualization technology. It could be accessed via web browsers （such as Google Chrome） supporting WebGL, at http：//***/synbioecoli/.

关键词： engineered E. coli three dimensional metabolic network biosynthetic ability

核磁共振谱研究PAA-F108-PAA嵌段共聚物的胶束化行为

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高等学校化学学报 2012年第7期33卷 1624-1630页

作者：孟令敏黄庆荣邓静吴亦洁石彤非中国科学院长春应用化学研究所高分子物理与化学国家重点实验室长春130022 中国科学院研究生院北京100049 Department of Food Science Rutgers UniversityNew Jersey08901USA 四Jll理工学院生物工程系自贡643000

采用原子转移自由基聚合伴随水解的方法合成了聚丙烯酸-聚醚嵌段共聚物(PAA-F108-PAA),并通过氢核磁共振波谱和二维核Overhauser效应谱(2. NOE)研究了温度、羧酸基团中和度(α)及盐浓度对PAA-F108-PAA嵌段共聚物在水溶液中胶束化行为的... 详细信息

采用原子转移自由基聚合伴随水解的方法合成了聚丙烯酸-聚醚嵌段共聚物(PAA-F108-PAA),并通过氢核磁共振波谱和二维核Overhauser效应谱(2. NOE)研究了温度、羧酸基团中和度(α)及盐浓度对PAA-F108-PAA嵌段共聚物在水溶液中胶束化行为的影响.结果表明,PAA-F108-PAA分子的临界胶束化温度受α影响较小,受盐的种类和浓度影响较大.当α=0.14(0.01 mol/L KCl)时,在6℃条件下,PAA-F108-PAA分子处于塌缩状态,而在60℃条件下,聚氧化丙烯(PPO)链段发生疏水聚集形成胶束的核,PAA链段与PEO链段相互作用形成胶束的壳;当α=0.80(0.01 mol/L KCl)时,在6℃条件下,PAA-F108-PAA分子处于相对伸展状态,而在60℃条件下,PPO链段仍发生疏水聚集形成胶束的核,PEO与PAA彼此分离形成胶束的壳.增加KCl的浓度至1 mol/L,PAA-F108-PAA分子的临界胶束化温度显著降低,KCl对PPO和PEO链段都表现出脱水作用.但KI的浓度增加至1 mol/L时,PAA-F108-PAA分子的临界胶束化温度仅略微增加,KI对PPO链段表现出脱水作用,而对PEO链段表现出增溶作用.

关键词：聚丙烯酸聚醚嵌段共聚物胶束化行为氢核磁共振波谱二维核Overhauser效应谱

Determination of Fe and Zn contents and distributions in natural sphalerite/marmatite by various analysis methods

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Transactions of Nonferrous Metals Society of china 2020年第5期30卷 1364-1374页

作者： Hao LAI Jiu-shuai deng Zi-long LIU Shu-ming WEN ling-yun HUANG State Key Laboratory of Complex Nonferrous Metal Resources Clean Utilization Faculty of Land Resource EngineeringKunming University of Science and TechnologyKunming 650093China School of chemical&Environmental Engineering China University of Mining and Technology(Beijing)Beijing 100083China Tibet Huatailong Mining Development Co. Ltd.Lhasa 850200China

The contents of Fe and Zn in natural sphalerite samples were determined by chemical titration and spectroscopic techniques(portable X-ray fluorescence(P-XRF) spectrometry, electron probe microanalysis with energy dispersive spectroscopy(EPMA-EDS), electron probe microanalysis with wavelength dispersive spectroscopy(EPMA-WDS), and time-of-flight secondary ion mass spectrometry(To F-SIMS)). Besides, the distribution of Fe and Zn in sphalerite samples was analyzed by imaging EPMA-WDS and imaging To F-SIMS. The results show that Fe and Zn contents determined by each spectroscopic technique have good linearity with those determined by chemical titration(R^2.0.77), and the R^2.values of Fe are generally greater than those of Zn. The imaging analysis results revealed that Fe and Zn are not uniformly distributed in the sphalerite.

关键词： sphalerite marmatite Fe Zn analysis methods imaging

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石油污染土壤修复技术的进展

化工环保 2012年第4期32卷 311-315页

作者：童玲陈伟胜郑西来邓建绵华北水利水电学院环境与市政工程学院河南郑州450011 中国海洋大学海洋环境与生态教育部重点实验室山东青岛266100

综述了石油污染土壤修复技术的发展现状及存在的瓶颈,分析了石油污染对油-水-土界面性质、土-水关系和土壤渗透性等水理性质的影响。对石油污染土壤再利用于工程建设进行了探讨,并总结了石油污染土壤主要的力学性质变化,为石油污染土壤... 详细信息

综述了石油污染土壤修复技术的发展现状及存在的瓶颈,分析了石油污染对油-水-土界面性质、土-水关系和土壤渗透性等水理性质的影响。对石油污染土壤再利用于工程建设进行了探讨,并总结了石油污染土壤主要的力学性质变化,为石油污染土壤修复技术的工程实践和机理研究提供参考。

关键词：石油污染土壤修复再利用水理特性力学性质

基于SEM-EDS的大气降尘特征及来源解析——以荒漠草原区井工开采煤炭基地为例

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中国环境科学 2021年第12期41卷 5512-5521页

作者：邓雅元赵廷宁张艳史常青岳丽玲陈童吴红璇胡平北京林业大学水土保持学院北京100083 国家能源集团宁夏煤业有限责任公司枣泉煤矿宁夏灵武751114

利用场发射扫描电子显微镜-配能谱分析系统(SEM-EDS)于2.19年3.5月对荒漠草原区煤炭基地及其周边5个功能区(煤炭工业区、煤炭运输道路、电力工业区、商住区和沙区)共计2.个大气降尘样品的粒径特征、微观形貌、单颗粒能谱图进行检测分析... 详细信息

利用场发射扫描电子显微镜-配能谱分析系统(SEM-EDS)于2.19年3.5月对荒漠草原区煤炭基地及其周边5个功能区(煤炭工业区、煤炭运输道路、电力工业区、商住区和沙区)共计2.个大气降尘样品的粒径特征、微观形貌、单颗粒能谱图进行检测分析.结果表明,各功能区大气降尘中颗粒物总体形貌基本相似,均包括近球状、类椭球状、颗粒状、块状和柱状/片状颗粒物以及烟尘集合体.此外,煤炭运输道路、电力工业区和商住区还存在球状颗粒物.各功能区大气降尘以>10μm颗粒物为主,其中,电力工业区、商住区、沙区和煤炭工业区大气降尘平均粒径均>100μm,且总量超过65%,煤炭运输道路大气降尘平均粒径为67.59μm,粒径>50μm的颗粒物量占53..大气降尘主要由细粉砂、粗粉砂和细砂组成.大气降尘中颗粒物的类型包括存在于各功能区中的硅酸盐矿物(石英、钾长石和斜长石)、碳酸盐矿物(方解石和白云石)、硫酸盐矿物(石膏)和高岭石,存在于煤炭运输道路、煤炭工业区和电力工业区中的富铁颗粒,存在于煤炭工业区中的铁镁颗粒,存在于煤炭运输道路、煤炭工业区、电力工业区和商住区中的烟尘集合体和燃煤飞灰.大气降尘来源主要为本地源,包括各功能区中均存在的地表扬尘、工业扬尘、建筑扬尘和大气中二次化学反应产物,煤炭运输道路、煤炭工业区和电力工业区中存在的机动车零件磨损产物,以及煤炭运输道路、煤炭工业区、电力工业区和商住区中存在的机动车尾气排放和燃煤产物.

关键词：大气降尘扫描电镜(SEM) 能谱分析(EDS) 形貌特征粒径特征来源