检索结果-南通市图书馆

Chemical Research in Chinese Universities 2010年第3期26卷 443-448页

作者： KE Xi deng lu-lu SHEN Pei-kang CUI Guo-feng State Key Laboratory of Optoelectronic Materials and Technologies School of Physics and Engineering School of Chemistry and Chemical Engineering Sun Yat-Sen University Guangzhou 510275 P. R. China

Pd was electrochemically deposited on gold-coated quartz crystals at nanogram-level. The coulombic efficiency and initial nucleation and growth mechanism of potentiostatic Pd deposition were investigated via in situ electrochemical quartz crystal microbalance（EQCM）. The coulombic efficieneies are 84%, 93% and 95% for Pd deposition at 0.3, 0.2 and 0.1 V（vs. SCE）, respectively. The results of chronoamperometric measurements show that the Pd deposition proceeded by an instantaneous nucleation（at 0.3 V） or progressive nucleation（at 0.2 and 0.1 V） in a three-dimensional（3D） growth mode. The catalytic activity of Pd-based electrocatalyst for ethanol oxidation was characterized in an alkaline solution. It was found that the highest mass activity for ethanol oxidation on Pd-based electrocatalyst is 1.8× 10^4 A/（g Pd） deposited at 0.3 V for 5 s.

关键词： Coulombic efficiency Nucleation and growth mechanism Electrochemical quartz crystal microbalance Palladium Ethanol oxidation

Ru doping triggering reconstruction of cobalt phosphide for coupling glycerol electrooxidation with seawater electrolysis

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Journal of Energy Chemistry 2025年第1期100卷 317-326页

作者： Binglu deng Jie Shen Jinxing lu Chuqiang Huang Zhuoyuan Chen Feng Peng Yunpeng Liu School of Materials Science and Hydrogen Energy Foshan University School of Chemistry and Chemical Engineering Guangzhou University Guangdong Key Laboratory for Hydrogen Energy Technologies

Seawater electrolysis is a promising approach for sustainable energy without relying on precious ***,the large-scale seawater electrolysis is hindered by low catalytic efficiency and severe anode corrosion caused by the harmful *** contrast to the oxygen evolution reaction （OER）and chlorin ion oxidation reaction （ClOR）,glycerol oxidation reaction （GOR） is more thermodynamically and kinetically favorable ***,a Ru doping cobalt phosphide （Ru-CoP2） is proposed as a robust bifunctional electrocatalyst for seawater electrolysis and GOR,for the concurrent productions of hydrogen and value-added *** in situ and ex situ characterization analyses demonstrated that Ru doping featured in the dynamic reconstruction process from Ru-CoP2to Ru-CoOOH,accounting for the superior GOR *** coupling GOR with hydrogen evolution was realized by employing Ru-CoP2as both anode and cathode,requiring only a low voltage of 1.43 V at 100 mA cm-2,which was 250 m V lower than that in alkaline *** work guides the design of bifunctional electrocatalysts for energy-efficient seawater electrolysis coupled with biomass resource upcycling.

关键词： Anodes

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我国国有森工企业融资分析

税务与经济 2011年第1期 52-54页

作者：邓露露东北林业大学经济管理学院吉林长春130025

我国经营开发国有林的主体是具有特殊的政企合一体制特征的国有森工企业,其以森林资源为主要经营对象,经营的既是一项产业,又是一项社会公益事业,兼有经济效益、生态效益和社会效益目标。资本是国有森工企业生产经营的经济基础,一直以... 详细信息

我国经营开发国有林的主体是具有特殊的政企合一体制特征的国有森工企业,其以森林资源为主要经营对象,经营的既是一项产业,又是一项社会公益事业,兼有经济效益、生态效益和社会效益目标。资本是国有森工企业生产经营的经济基础,一直以来其资本的主要来源是依靠政府的投资和配套政策的支持以及国有银行的金融信贷,而近年来资本市场等融资方式也逐渐被我国国有森工企业所采用。

关键词：国有森工企业融资结构资本市场

金融消费者保护:信息不对称、双重道德风险的防范

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湖南大学学报（社会科学版） 2015年第6期29卷 156-160页

作者：崔金珍邓露露天津财经大学法学院天津300222

对金融消费者进行保护的最根本原因是金融交易中的金融机构处于信息优势地位而引发的道德风险问题损害了处于弱势地位的金融消费者的合法权益。然而,通常容易被忽视的是当金融消费者处于信息优势地位及过度的金融消费者保护而引发的道... 详细信息

对金融消费者进行保护的最根本原因是金融交易中的金融机构处于信息优势地位而引发的道德风险问题损害了处于弱势地位的金融消费者的合法权益。然而,通常容易被忽视的是当金融消费者处于信息优势地位及过度的金融消费者保护而引发的道德风险问题。通过运用经济学当中的信息不对称理论、委托代理理论对金融交易中产生的双重道德风险进行分析,更好地防范双重道德风险的产生,保护金融消费者的权益。

关键词：金融消费者道德风险信息不对称

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国有森工企业融资对策研究

吉林农业大学学报 2011年第4期33卷 469-472页

作者：邓露露耿玉德东北林业大学经济管理学院哈尔滨150000 吉林财经大学会计学院长春130000

我国国有森工企业负债融资比例较高,资本结构单一,企业融资较为困难。文中在分析了我国国有森工企业融资中存在问题的基础上,积极地提出融资对策,旨在解决我国国有森工企业的融资困境,进而促进国有森工企业及林业建设的快速发展。

关键词：国有森工企业融资融资模式

A new bufadienolide with cytotoxic activity from the Chinese traditional drug Ch'an Su

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Chinese Journal of Natural Medicines 2014年第8期12卷 623-627页

作者： XU Ran XIE Hai-Qin deng lu-lu ZHANG Jian-Xin YANG Fu-Mei LIU Jian-Hua HAO Xiao-Jiang ZHANG Yuan-Hu The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences

AIM: To study the bufadienolides in the Chinese traditional drug "Ch'an Su" and their cytotoxic activity. METHOD: Various chromatographic techniques were used to isolate the constituents, and their structures were elucidated through physical and spectroscopic data. RESULTS: Twenty compounds were isolated, and eighteen were evaluated in vitro for their cytotoxic activity against A-549 and K-562 cells. CONCluSION: Compound 1(bufalin 3β-acrylic ester) was a new bufadienolide and exhibited the most potent activity against the two tumor cell lines with IC50 values of 7.16 and 6.83 nmol·L–1. The relationships between structure and activity are discussed.

关键词： "Ch'an Su" New bufadienolide Bufalin 3fi-acrylic ester Cytotoxicity

巧克力专用油脂在烘焙和冰淇淋涂层食品中的应用与发展

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食品工业科技 2017年第1期38卷 391-394,400页

作者：梁军邓璐璐益海嘉里食品营销有限公司上海200120

巧克力涂层与烘焙类、冰淇淋类等食品的复合型产品一直以来都广受消费者欢迎。而不同的食品类别对涂层巧克力专用油脂的性能和品质要求不同。本文分别对巧克力专用油脂在烘焙和冰淇淋两大涂层类食品中的应用进行分析和探讨,并展望了巧... 详细信息

巧克力涂层与烘焙类、冰淇淋类等食品的复合型产品一直以来都广受消费者欢迎。而不同的食品类别对涂层巧克力专用油脂的性能和品质要求不同。本文分别对巧克力专用油脂在烘焙和冰淇淋两大涂层类食品中的应用进行分析和探讨,并展望了巧克力涂层专用油脂未来的发展趋势。

关键词：巧克力涂层专用油脂

西吡氯铵修饰的脂质体用于氯诺昔康的经皮局部递送

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中国医院药学杂志 2023年第4期43卷 376-382页

作者：胡熙曦邓璐璐陈倩宜昌市第二人民医院药学部·三峡大学第二人民医院湖北省老年胃肠癌精准防治临床医学研究中心湖北宜昌443000 宜昌市优抚医院药学部湖北宜昌443000 宜昌市第三人民医院皮肤科湖北宜昌443000

目的:研究一种可用于氯诺昔康局部递送的经皮给药系统。方法:比较不同处方脂质体(普通脂质体和传递体)的理化性质,优选最佳处方;将该给药系统应用于猪皮肤,通过Franz扩散池进行离体皮肤渗透研究。结果:以0.8%的磷脂酰胆碱制备的囊泡具... 详细信息

目的:研究一种可用于氯诺昔康局部递送的经皮给药系统。方法:比较不同处方脂质体(普通脂质体和传递体)的理化性质,优选最佳处方;将该给药系统应用于猪皮肤,通过Franz扩散池进行离体皮肤渗透研究。结果:以0.8%的磷脂酰胆碱制备的囊泡具有较高的包封率和载药量,粒径小于200 nm,粒径分布均匀(PDI<0.3);比较囊泡通量值发现,传递体具有最高的渗透系数,沉积在表皮层和真皮层中的药物量也观察到类似的结果。结论:传递体的形变能力使其能更好地渗透到更深的皮肤层;阳离子表面活性剂对角质层脂质组织的破坏增强了药物在皮肤中的递送能力。传递体有效增强了活性成分的吸收,在治疗作用上将表现得更好。

关键词：传递体脂质体离体皮肤渗透氯诺昔康

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滇产两面针中抗肿瘤活性生物碱成分研究

天然产物研究与开发 2020年第8期32卷 1370-1378页

作者：邓颖沈晓华邓璐璐郝小江穆淑珍贵州大学药学院贵阳550025 贵州医科大学省部共建药用植物功效与利用国家重点实验室贵州省中国科学院天然产物化学重点实验室贵阳550014

从滇产两面针的干燥根中分离得到12个化合物,通过其一维或二维核磁共振谱、质谱和理化性质的解析并结合文献鉴定了它们的结构,分别为9-去甲氧基两面针碱(1)、8-dehydroxyl-buesgenine(2)、6β-hydroxymenthyldihydronitidine(3)、花椒木... 详细信息

从滇产两面针的干燥根中分离得到12个化合物,通过其一维或二维核磁共振谱、质谱和理化性质的解析并结合文献鉴定了它们的结构,分别为9-去甲氧基两面针碱(1)、8-dehydroxyl-buesgenine(2)、6β-hydroxymenthyldihydronitidine(3)、花椒木精(4)、rhoifoline B(5)、两面针碱(6)、白屈菜红碱(7)、博落回碱(8)、白鲜碱(9)、γ-崖椒碱(10)、茵芋碱(11)和鹅掌楸碱(12)。其中,化合物1和2为新结构化合物。通过MTT法,首次评价了化合物1~12对黑色素瘤细胞WM9增殖的抑制活性,并发现化合物3和6对WM9细胞的增殖表现出较强的活性,半数抑制浓度(IC50)值分别为1.936μM和0.880μM,研究结果为抗肿瘤药物候选药物分子的发现提供了科学依据。

关键词：滇产两面针芸香科生物碱苯骈菲啶类黑色素瘤

High-dose dexamethasone regulates microglial polarization via the GR/JAK1/STAT3 signaling pathway after traumatic brain injury

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Neural Regeneration Research 2025年第9期20卷 2611-2623页

作者： Mengshi Yang Miao Bai Yuan Zhuang Shenghua lu Qianqian Ge Hao Li Yu deng Hongbin Wu Xiaojian Xu Fei Niu Xinlong Dong Bin Zhang Baiyun Liu Beijing Tiantan Hospital Capital Medical UniversityBeijingChina Department of Neurology The First Hospital of Tsinghua UniversityBeijingChina Department of Neurotrauma and Beijing Key Laboratory of Central Nervous System Injury Beijing Neurosurgical InstituteCapital Medical UniversityBeijingChina Department of Critical Care Medicine Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Center for Nerve Injury and Repair Beijing Institute of Brain DisordersChina National Clinical Research Center for Neurological DiseasesBeijingChina

Although microglial polarization and neuroinflammation are crucial cellular responses after traumatic brain injury,the fundamental regulatory and functional mechanisms remain insufficiently *** potent anti-inflammato ry agents,the use of glucoco rticoids in traumatic brain injury is still controversial,and their regulatory effects on microglial polarization are not yet *** the present study,we sought to determine whether exacerbation of traumatic brain injury caused by high-dose dexamethasone is related to its regulatory effects on microglial polarization and its mechanisms of *** vitro cultured BV2 cells and primary microglia and a controlled cortical impact mouse model were used to investigate the effects of dexamethasone on microglial ***,dexamethasone,RU486(a glucocorticoid receptor antagonist),and ruxolitinib(a Janus kinase 1 antagonist)were ***-sequencing data obtained from a C57BL/6 mouse model of traumatic brain injury were used to identify potential targets of *** Morris water maze,quantitative reverse transcription-polymerase chain reaction,western blotting,immunofluorescence and confocal microscopy analysis,and TUNEL,Nissl,and Golgi staining were performed to investigate our ***-throughput sequencing results showed that arginase 1,a marker of M2 microglia,was significantly downregulated in the dexamethasone group compared with the traumatic brain injury group at3 days post-traumatic brain *** dexamethasone inhibited M1 and M2 microglia,with a more pronounced inhibitory effect on M2microglia in vitro and in *** receptor plays an indispensable role in microglial polarization after dexamethasone treatment following traumatic brain ***,glucocorticoid receptor activation increased the number of apoptotic cells and neuronal death,and also decreased the density of dendritic spines.A possible downstream receptor signaling mechanism is th

关键词： apoptosis BV2 microglia dexamethasone glucocorticoid receptor glucocorticoids innate immune system microglial polarization neuroinflammation primary microglia traumatic brain injury