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新型炭材料 2003年第4期18卷 265-270页

作者：陆安慧 Jan-Henrik Smtt mika Lindn Ferdi Schüth max-Planck-Institut für Kohlenforschung Kaiser-Wilhelm-Platz 1D-45470 Mülheim an der Ruhr max-Planck-Institut für Kohlenforschung Kaiser-Wilhelm-Platz 1 D-45470 Mülheim an der Ruhr

　以多孔块状硅体为模板,通过一步浸渍、炭化、酸处理工艺,制备出结构可控、孔隙联通且具有多重孔隙的铸型炭体。分别采用氮吸附技术、高分辨透射电镜和扫描电镜对模板硅、硅碳复合物及相应炭体进行了结构表征。从微米尺度分析,该炭体... 详细信息

　以多孔块状硅体为模板,通过一步浸渍、炭化、酸处理工艺,制备出结构可控、孔隙联通且具有多重孔隙的铸型炭体。分别采用氮吸附技术、高分辨透射电镜和扫描电镜对模板硅、硅碳复合物及相应炭体进行了结构表征。从微米尺度分析,该炭体是由高度联接的枝状结构单元为骨架构筑而成。与模板硅相比较,此炭体是硅体的正复本。从纳米尺度分析,这种炭体枝状骨架是由分布均匀且相互连接的中孔构成,此中孔及其孔壁对应于模板硅的孔壁及中孔,是多孔硅的负复本。此外构成中孔的炭骨架本体又含有大量炭化过程产生的微孔。因此该法合成的铸型炭具有孔隙高度发达和结构层层嵌套的特点。

关键词：铸型炭体一步浸渍法合成多重孔隙结构表征

Detection of Human Papillomavirus DNA and E6/E7 mRNA from HPV Genotypes 16, 18, 31 and 33 in Histologically Confirmed Cases of Cervical Cancer and Precancerous Lesions in Burkina Faso

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American Journal of molecular Biology 2023年第4期13卷 276-290页

作者： théodora mahoukèdè Zohoncon Shoukrat Ohuwa Toyin Bello Prosper Bado Rogomenoma Alice Ouédraogo Estelle Ouédraogo Ina marie Angèle Traoré Abdoul Karim Ouattara Florencia Wenkunni Djigma Albert théophane Yonli Assita Sanou-Lamien Olga mélanie Lompo Jacques Simpore Laboratoire de Biologie moléculaire et de Génétique (LABIOGENE) Université Joseph KI-ZERBO Ouagadougou Burkina Faso Centre de Recherche Biomoléculaire Pietro Annigoni (CERBA) Ouagadougou Burkina Faso Faculté des Sciences de la Santé Université Saint Thomas d’Aquin (USTA) Ouagadougou Burkina Faso Centre Hospitalo-Universitaire Yalgado Ouedraogo Ouagadougou Burkina Faso Pathological Anatomy and Cytology Laboratory Université Joseph Ki-Zerbo Ouagadougou Burkina Faso

Introduction: Cervical cancer, caused by persistent high-risk human papillomavirus (HPV) infection, remains a global public health problem. the cellular transformation and maintenance of the malignant phenotype of these HPVs are attributed to the viral oncoproteins E6 and E7. Objective: this study aims to detect the presence of human papillomavirus DNA and E6/E7 oncoprotein mRNA of HPV genotypes 16, 18, 31 and 33 in cases of cervical cancer and precancerous lesions, histologically confirmed in Burkina Faso. methods: this descriptive cross-sectional study focused on cases of cervical cancer and high-grade intraepithelial neoplasia (CIN) and was conducted from June to December 2022. One hundred (100) samples of fixed and paraffin-embedded tissues were collected from the pathological anatomy and cytology laboratories of hospitals in the capital of Burkina Faso. High-risk human papillomavirus (HR-HPV) DNA was detected using multiplex real-time PCR, while the presence of E6 and E7 mRNA in cervical cancer and high-grade CIN samples was determined using real-time Reverse Transcriptase-PCR (RT-PCR) with Taqman probes. Results: the mean age of women diagnosed with cervical cancer and high-grade CIN was 50.81 ± 13.65 years, ranging from 22 to 82 years. Cervical cancer and high-grade CIN were positive for at least one high-risk human papillomavirus (HR-HPV) in 80% of cases. the most prevalent genotypes observed were HPV16, 18, 31, and 33, collectively accounting for 70.08% of cases. Of the 89 samples that tested positive for HR-HPV genotypes 16, 18, 31, and 33, 88 (98.88%;95% CI: [94.58 - 99.94]) were also positive for the presence of mRNA encoding the E6 and E7 oncoproteins of HPV16, 18, 31, and 33. Conclusion: In the presence of HPV DNA, testing for E6 and E7 oncoprotein mRNA could serve as a promising biomarker and valuable tool for improved assessment of the progression to cervical cancer.

关键词： HPV E6/E7 Cervical Cancer Precancerous Lesions Burkina Faso

轮对用万向轴驱动的二轴转向架上作用力的分析

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国外铁道机车与动车 1964年第1期 27-33+21页

作者： C.th.müller 万德立

现在,用万向轴联接的轮对,广泛地用于铁道机车制造中,因而可以理解,为什么万向轴的载荷问题,特别是其扭转载荷的问题,在铁路上面成了研究和试验的对象。这种驱动中存在的问题,与多轴驱动汽车上的基本上相同。由于汽车制造中比铁路上早... 详细信息

现在,用万向轴联接的轮对,广泛地用于铁道机车制造中,因而可以理解,为什么万向轴的载荷问题,特别是其扭转载荷的问题,在铁路上面成了研究和试验的对象。这种驱动中存在的问题,与多轴驱动汽车上的基本上相同。由于汽车制造中比铁路上早采用这种驱动,所以在西德和国外汽车制造的

关键词：万向轴符号摩擦功打滑率

2.9mm Series Phase adjustable Connectors

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2.9mm Series Phase adjustable Connectors

1996年第四届毫米波和远红外科学与技术国际会议

作者： 40th Rescarch Institute of mEI Li mingde

＜正＞this paper describes design concept of UPT 2.9 series phase adjustable connectors and adapters with operating frequency up to 40GHz （usable to 46GHz） and low VSWR characteristic,the measures to extend frequency *** relating problems are discussed such as phase adjusting precision,phase adjusting range and upper frequency limit, and the measuring curves are also given.

关键词：

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由低速支路合成的高速扰码和解扰码

通信学报 1991年第1期12卷 74-77页

作者：李秉钧邮电部第五研究所

在原理上虽然高速数字通信扰码同低速扰码相同,但由于工程实现中的困难必须考虑新的高速系统。本文讨论的系统,在低速支路速率下产生一套m序列,用来对支路码流扰码或解扰;在群路中,扰码后的码流通过复接合成高速码流,该码流等效于在群... 详细信息

在原理上虽然高速数字通信扰码同低速扰码相同,但由于工程实现中的困难必须考虑新的高速系统。本文讨论的系统,在低速支路速率下产生一套m序列,用来对支路码流扰码或解扰;在群路中,扰码后的码流通过复接合成高速码流,该码流等效于在群路扰码产生的码流,这个码流在接收侧群路被分解为支路。在保证等效性的前提下此系统中多数部分工作在支路速率,降低了工程实现的困难。为保证这种等效性本文分析了在设计中必须保证满足的三个条件。组合逻辑是本系统的关键。表1中给出支路组合逻辑的一些设计结果,这些基于理论推导又被计算机模拟证明其正确性的结果在设计中可直接采用。本系统还兼有定时系统的功能。

关键词：扰码解扰码数字通信

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水肿之疗法

中华医学杂志 1933年第1期19卷 77-78页

作者： J.A.m.A., June, 18th, 1932

Barker氏谓水肿老食无盐食品而获裨益者,不在不会氯,而在不食钠。氏用狗作实验,见其患人工水肿者若不食钠则水肿能渐次消退,若以钾代钠则水肿之消退较速。病者另食重炭酸钠或含枸机酸钠之水果,则虽禁绝氯化钠亦无用。氏调若将食品内之...

Barker氏谓水肿老食无盐食品而获裨益者,不在不会氯,而在不食钠。氏用狗作实验,见其患人工水肿者若不食钠则水肿能渐次消退,若以钾代钠则水肿之消退较速。病者另食重炭酸钠或含枸机酸钠之水果,则虽禁绝氯化钠亦无用。氏调若将食品内之氯化钠代以氯化钾(每日五克),则病人中

关键词：

therapy of multiple myeloma

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the Chinese-German Journal of Clinical Oncology 2002年第3期1卷 141-144页

作者： H.Goldschmidt F.W.Crmer th.möhler A.Krämer m.Görner G.Egerer A.D.Ho Department of Internal medicine V University of Heidelberg Hospitalstr.3 D-68115Germany

Summary multiple myeloma(mm)is characterised by the accumulation of malignant plasma cells in the bone marrow producing a monoclonal *** standard conventional therapy is the combination of melphalan and prednisone resulting in a response rate of 40%-60%and in a median survival time of approximately 3 *** order to improve the therapeutic efficacy various combination regimens have been *** randomized trials have frailed to show a significant improvement in survival time when combination chemotherapy is used instead of melphalan with or without *** benefit of maintenance therapy with interferon-alpha has been *** toxicity of interferon-alpha,which may reduce the quality of life,should be ***,myeloma-treatment has been ***-dose chemotherapy accompanied by hematopoietic stem-cell support via autologous transplant is recommended up to the age of 65-70 *** results from a French study comparing single versus double autologous transplantation have shown a benefit in terms of event-free survival for the sequential *** as an adoptive immuntherapy to treat minimal residual disease are under *** mortality rale of allogeneic transplantation of hematopoietic stem cells has been reduced in the last 5 *** use of reduced conditioning regimens or the partial depletion of T cells in peripheral blood stem cell transplants in an effort to decrease transplant related mortality are promising ***-omide and its derivates are a new class of agents with independent anti-tumour activity in *** results with this antian-giogenic therapy in phase II trials have been *** therapies,such as the treatment of anaemia with erythropoietin,the management of renal failure and the use of bisphosphonates,improve the life quality of mm patients.

关键词： multiple myeloma treatment transplantation angiogenesis

“畸变工程”:从系统的角度探讨零件的畸变现象

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金属热处理 2004年第11期29卷 43-50页

作者： Klaus-Dieterthoben DieterKlein th.Luebben B.Clausen Chr.Prinz A.Schulz R.Rentsch R.Kusmierz L.Nowag H.Surm F.Frerichs m.Hunkel P.mayr BremenInstituteofIndustrialTechnologyandAppliedWorkScience（BIBA） BremenGermany InstituteformaterialScience（IWT） BremenGermany

在产品的最终加工过程中用精磨去除零件中的畸变是一个既费钱又费时的事情。例如 ,仅在 (车辆 )传动技术领域 ,1995年德国用于最后精磨以消除工件的畸变而增加的成本已达 8 5亿欧元。迄今为止 ,行业人士认为在最后的产品加工过程中导致... 详细信息

在产品的最终加工过程中用精磨去除零件中的畸变是一个既费钱又费时的事情。例如 ,仅在 (车辆 )传动技术领域 ,1995年德国用于最后精磨以消除工件的畸变而增加的成本已达 8 5亿欧元。迄今为止 ,行业人士认为在最后的产品加工过程中导致零件产生畸变的主要原因在于淬火过程 ,而今大家普遍认为这个观点不是很对 ,认为淬火过程只是释放了在各个加工环节中积累在工件中的畸变潜能 ,如铸造、车削加工、铣削、淬火、磨削。由不来梅大学创立及DeutscheForschungsgemeinschaft资助的合作研究中心SFB 5 70“畸变工程”的研究方针是从系统导向着手 ,分析零件的畸变。合作研究中心由 12个子项目组成 ,涉及 2 0多位来自材料科学、制造技术、数学及过程控制工程的研究人员。根据系统导向的方法 ,合作研究中心SFB 5 70“畸变工程”认为 ,与优化零件整个生产过程 (工序链 )相比 ,对零件生产过程中的单个过程的优化是第二位的。为了推广系统导向的方法 ,保证SFB 5 70“畸变工程”中集中在不同工序和技术的这 12个子项目间的一个连续、协调的知识和信息交换 ,已成立了一个系统模式工作组。这个工作组的焦点在于详细阐述和进一步发展系统导向的方法以及协调应用于这些子项目中的工序和方法。和其它方法相比较 ,整体方法包?

关键词：变现工程项目系统欧元协调行业导向潜能数学

Geoelectric Investigation for Groundwater Exploration in YaoundéArea, Cameroon

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International Journal of Geosciences 2012年第3期3卷 640-649页

作者： William Assatsé. Teikeu Philippe Nouck Njandjock théophile Ndougsa-mbarga Tabod Charles Tabod Department of Physics Advanced Teachers’ Training College University of Yaounde I P.O. Box 47 Yaounde Cameroon Department of Physics Faculty of Science University of Yaounde I P.O. Box 812 Yaounde Cameroon

Yaounde zone is originally characterized by the small number of aquifers and bad renewal capacity. Within the frame-work of the emergency program which aims at supplying the city with drinking water, seventeen Vertical Electrical Soundings (VES) were carried out using Schlumberger configuration in parts of Yaounde (latitude 3o- 5oN and longi- tude 11o-13oE) to determine the nature and thickness of aquifer zone and necessary geoelectrical parameters. Four to five geoelectric layers were delineated from the survey area. the first layer is the topsoil and has resistivity values ranging from 13 - 216 Ω·m and thickness is between 0.1 - 6 m. the second layer made up of clay sand and laterite has resistivity values ranging between 23 and 923 Ω·m and thickness ranged from 1 and 40 m. the third and fourth geoelectric layers consisting of clay and gneiss/migmatite with thickness varying from 1.7 - 63.3 m correspond to an aquifer horizon. Resistivity values of the aquifer ranges from 4 to 9215 Ω·m. the study indicates that average depth of the aquifer is 20 m and average thickness of the aquifer is 55 m. Soundings curves suggest several four layered geoelectrical sections KH, KQ, HK type and some five layered sections of the HKH, KHK types. KH type is dominant and can be used as reference for future studies. the resistivity survey reveals that the parameters obtained through interpretation of VES curves corroborate the litho logs of boreholes from the area.

关键词： Aquifer Geoelectrical Section Vertical Electrical Sounding (VES) Yaoundé