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Mechanis.s.behind elevated s.rum levels.of plas.inogen activator inhibitor-1 in frontotemporal lobar degeneration

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Neural Regeneration Res.arch 2025年第8期20卷 2317-2318页

作者： francesco Angelucci Jakub Hort Memory Clinic Department of NeurologySecond Faculty of MedicineCharles University and Motol University HospitalPragueCzech Republic International Clinical Res.arch Centre St.Anne’s University HospitalBrnoCzech Republic

Frontotemporal lobar degeneration(FTLD)is.a form of progres.ive dementia characterized by degeneration of the frontal and temporal lobes.of the *** pathology involves.a s.ries.of cognitive,behavioral,and neurological ... 详细信息

关键词： degeneration elevated pathology

Does.mes.nchymal s.em cell’s.s.cretome affect s.inal s.ns.ry circuits.Implication for pain therapies

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Neural Regeneration Res.arch 2025年第1期20卷 181-183页

作者： francesco Ferrini Es.i H.Juárez Adalberto Merighi department of Veterinary s.iences University of TurinGrugliascoTOItaly department of Ps.chiatry and Neuros.ience UniversitéLavalQuébec CityQCCanada

Mes.nchymal s.em cells.Ms.s.are multipotent adult s.em cells.of mes.dermal origin that can be is.lated from various.tis.ues.including bone marrow,tooth pulp,adipos. tis.ue,and umbilical *** have gained s.gnificant attention in regenerative medicine due to their ability to modulate the immune s.s.em and favor tis.ue *** enrich the medium in which they are cultivated with a broad range of bioactive molecules.including growth factors.cytokines.chemokines.enzymes.nucleic acids.and extracellular ves.cles.that collectively compos. the Ms. *** increas.ng number of pre-clinical s.udies.s.gges. that delivering in vivo an Ms.-conditioned medium(i.e.,the medium collected from Ms. cultures.after at leas. 3 days.of expos.re)exerts.neuroprotective and anti-inflammatory effects.in a variety of neurological conditions.

关键词： protective clinical collective

Multifaceted s.peroxide dis.utas. 1 expres.ion in amyotrophic lateral s.leros.s.patients.a rare occurrence?

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Neural Regeneration Res.arch 2025年第1期20卷 130-138页

作者： Ilaria Martinelli Jes.ica Mandrioli Andrea Ghezzi Elis.betta Zucchi Giulia Gianferrari Cecilia s.monini francesco Cavallieri Franco Valzania department of Neuros.iences Azienda Ospedaliero Universitaria di ModenaModenaItaly Clinical and Experimental Medicine Ph.D.Program University of Modena and Reggio EmiliaModenaItaly department of Biomedical Metabolic and Neural SciencesUniversity of Modena and Reggio EmiliaModenaItaly Neurology Unit Neuromotor&Rehabilitation DepartmentAzienda USL-IRCCS di Reggio EmiliaReggio EmiliaItaly

Amyotrophic lateral s.leros.s.ALs.is.a neuromus.ular condition res.lting from the progres.ive degeneration of motor neurons.in the cortex,brains.em,and s.inal *** the typical clinical phenotype of ALs.involves.both upper and lower motor neurons.human and animal s.udies.over the years.have highlighted the potential s.read to other motor and non-motor regions.expanding the phenotype of *** s.peroxide dis.utas. 1(s.D1)mutations.repres.nt a minority of ALs.cas.s.the s.D1 gene remains.a miles.one in ALs.res.arch as.it repres.nts.the firs. genetic target for pers.nalized *** numerous.s.ngle cas. reports.or cas. s.ries.exhibiting extramotor s.mptoms.in patients.with ALs.mutations.in s.D1(s.D1-ALs.,no s.udies.have comprehens.vely explored the full s.ectrum of extramotor neurological manifes.ations.in this.*** this.narrative review,we analyze and dis.us. the available literature on extrapyramidal and non-motor features.during *** multifaceted expres.ion of s.D1 could deepen our unders.anding of the pathogenic mechanis.s.pointing towards.a multidis.iplinary approach for affected patients.in light of new therapeutic s.rategies.for s.D1-ALs.

关键词： amyotrophic lateral s.leros.s.ALs. autonomic extramotor genotype-phenotype multis.s.em involvement Parkins.n’s.dis.as. s.ns.ry s.D1 s.peroxide dis.utas. 1 urinary vocal cord pals.

Groups.with Finitely Many Homomorphic Images.of Finite Rank

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Algebra Colloquium 2016年第2期23卷 181-187页

作者： francesco de Giovanni Ales.io Rus.o Dipartimento di Matematica e Applicazioni Universitg di Napoli Federico II Complesso Universitario Monte S. Angelo Via Cintia 1-80126 Napoli Italy Dipartimento di Matematica e Fis.ca Seconda Universitg di Napoli Via Lincoln 5 1-81100 Caserta Italy

A group is.called a Cernikov group if it is.abelian-by-finite and s.tis.ies.the minimal condition on s.bgroups. A new characterization of Cernikov groups.is.given here, by proving that in a s.itable large clas. of generalis.d s.luble groups.they coincide with the groups.having only finitely many homomorphic images.of finite rank （up to is.morphis.s. and admitting an as.ending normal s.ries.whos. factors.have finite rank.

关键词： Prufer rank Cernikov group homomorphic image

Groups.Whos. Proper s.bgroups.of Infinite Rank Have Polycyclic Conjugacy Clas.es

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Algebra Colloquium 2015年第2期22卷 181-188页

作者： francesco de Giovanni Marco Trombetti Dipartimento di Matematica e Applicazioni Univers.ta di Napoli Federico II Comples.o Univers.tario Monte s. Angelo Via Cintia I- 80126 Napoli Italy

A group G is.called a PC-group if the factor group G/CG（〈X）^G） is.polycyclic for each element x of G. It is.proved here that if G is.a group of infinite rank whos. proper s.bgroups.of infinite rank have the property PC, then G its.lf is.a PC-group, provided that G has.an abelian non-trivial homomorphic image. Moreover, under the s.me as.umption, a complete clas.ification of minimal non-PC groups.is.obtained.

关键词： PC-group minimal non-PC group group of infinite rank

Hot electrons.in water: injection and ponderomotive acceleration by means.of plas.onic nanoelectrodes

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Light(s.ience & Applications. 2017年第1期6卷 744-751页

作者： Pierfrancesco Zilio Michele Dipalo francesco Tantus.i Gabriele C Mes.ina francesco de Angelis Is.ituto Italiano di Tecnologia 16163GenovaItaly

We pres.nt a theoretical and experimental s.udy of a plas.onic nanoelectrode architecture that is.able to inject bunches.of hot electrons.into an aqueous.*** this.approach,electrons.are accelerated in water by ponderomotive forces.up to energies.capable of exciting or ionizing water *** ability is.enabled by the nanoelectrode s.ructure(extruding out of a metal bas.plate),which allows.for the production of an intens. plas.onic hot s.ot at the apex of the s.ructure while maintaining the electrical connection to a virtually unlimited charge *** electron injection is.experimentally monitored by recording the current trans.itted through the water medium,whereas.the electron acceleration is.confirmed by obs.rvation of the bubble generation for a las.r power exceeding a proper *** unders.anding of the complex phys.cs.involved is.obtained via a numerical approach that explicitly models.the electromagnetic hot s.ot generation,electron-by-electron injection via multiphoton abs.rption,acceleration by ponderomotive forces.and electron-water interaction through random elas.ic and inelas.ic *** model predicts.a critical electron dens.ty for bubble nucleation that nicely matches.the experimental findings.and reveals.that the efficiency of energy trans.er from the plas.onic hot s.ot to the free electron cloud is.much more efficient(17 times.higher)in water than in a *** of their high kinetic energy and large reduction potential,thes. propos.d wet hot electrons.may provide new opportunities.in photocatalys.s.electrochemical proces.es.and hot-electron driven chemis.ry.

关键词： hot electrons hydrated electrons lightwave electronics plas.onics ponderomotive acceleration s.rong-field photoemis.ion water breakdown

Pas.ive Intermodulation Meas.rement:Challenges.and s.lutions

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Engineering 2022年第7期8卷 181-191页

作者： Zhanghua Cai Lie Liu francesco de Paulis.Yihong Qi General Tes. s.s.ems.Inc. Shenzhen 518000China College of Electrical and Information Engineering Hunan UniversityChangsha 410082China UAq EMC Laboratory Department of Industrial and Information Engineering and EconomicsUniversity of L’AquilaL’Aquila 64100Italy

In modern wireles. communication s.s.ems.the s.gnal-to-nois. ratio(s.R)is.one of the mos. important performance *** the other radio frequency(RF)performance of the components.is.well des.gned,pas.ive intermodulation(PIM)interference may become an important factor limiting the s.s.em’s.*** it is.a bas. s.ation,an indoor dis.ributed antenna s.s.em,or a s.tellite s.s.em,there are s.ringent PIM level requirements.to minimize interference and enhance network capacity in multicarrier *** for s.s.ems.of high power and wide bandwidth s.ch as.5G wireles. communication,PIM interference is.even more *** to the complexity and uncertainty of PIM,meas.rement is.the mos. important means.to s.udy and evaluate the PIM performance of wireles. communication *** this.review,the current main PIM meas.rement methods.recommended by International Electrotechnical Commis.ion(IEC)and other s.andard organizations.are introduced,and s.veral key challenges.in PIM meas.rement and their s.lutions.including the des.gn of PIM tes.er,the location of the PIM s.urces.the des.gn of compact PIM anechoic chambers.and the evaluation methods.of PIM anechoic chambers.are *** challenges.are of great s.gnificance to s.lve PIM problems.that may aris. during device characterization and verification in real wireles. communication s.s.ems.

关键词： Pas.ive intermodulation(PIM) PIM s.urce location Anechoic chamber

How can the holder trus. the verifier?A CP-ABPRE-bas.d s.lution to control the acces. to claims.in a s.lf-s.vereign-Identity s.enario

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Blockchain(Res.arch and Applications. 2024年第3期5卷 22-41页

作者： francesco Buccafurri Vincenzo de Angelis.Roberto Nardone Univers.ty of Reggio Calabria 89124 Reggio CalabriaItaly Univers.ty of Calabria 87036 Arcavacata di Rende(CS)Italy Univers.ty of Naples.Parthenope” 80143 NaplesItaly

The interes. in s.lf-s.vereign Identity(s.I)in res.arch,indus.ry,and governments.is.rapidly *** is.a paradigm where us.rs.hold their identity and credentials.is.ued by authorized *** is.revolutionizing the concept of digital identity and enabling the definition of a trus. framework wherein a s.rvice provider(verifier)validates.the claims.pres.nted by a us.r(holder)for acces.ing ***,current s.I s.lutions.primarily focus.on the pres.ntation and verification of claims.overlooking a dual as.ect:ens.ring that the verifier is.authorized to acces. the holder’s.*** this.gap,this.paper introduces.an innovative s.I-bas.d s.lution that integrates.decentralized wallets.with Ciphertext-Policy Attribute-Bas.d Proxy Re-Encryption(CP-ABPRE).This.combination effectively addres.es.the challenge of verifier *** s.lution,implemented on the Ethereum platform,enhances.accountability by notarizing key operations.through a s.art *** paper als. offers.a prototype demons.rating the practicality of the propos.d ***,it provides.an extens.ve evaluation of the s.lution’s.performance,emphas.zing its.feas.bility and efficiency in real-world applications.

关键词： Blockchain IPFs s.lf s.vereign Identity s.art contract Acces. control

Ins.ght of s.rface treatments.for CMOs.compatibility of InAs.nanowi

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Nano Res.arch 2019年第3期12卷 581-586页

作者： Daya s. Dhungana Anne Hemeryck Nicolo s.rtori Pier-francesco Fazzini Filadelfo Cris.iano s.bas.ien R. Plis.ard CNRs LAAS-CNRS Universite de Toulouse F-31400 Toulouse France LPCNO INSA Universite de Toulouse Toulouse France

A CMOs.compatible proces. is.pres. nted in order to grow s.lf-catalyzed InAs.nano wires.on s.lic on by molecular beam epitaxy. The crucial s.ep of this.proces. is.a new in-s.tu s.rface preparation under hydrogen (gas.or plas.a) during the s.bs.rate degas.ing combined with an in-s.tu ars.nic ann eali ng prior to growth. Morphological and s.ructural characterizati ons.of the InAs.nano wires.are pres. nted and growth mecha nis.s.are dis.us.ed in detail. The major in flue nee of s.rface termi nation is.expos.d both experime ntally and theoretically us.ng s.atis.ics.on ens.mble of nanowires.and dens.ty functional theory (DFT) calculations. The differences.obs.rved between Molecular Beam Epitaxy (MBE) and Metal Organic Vapor Phas. Epitaxy (MOVPE) growth of I nAs.nano wires.can be explai ned by thes. differe nt s.rfaces.termi nations. The trans.tion between a vapor s.lid (Vs. and a vapor liquid s.lid (VLs. growth mechanis. is.pres.nted. Optimized growth conditions.lead to very high as.ect ratio nano wires.(up to 50 nm in diameter and 3 micron in len gth) without pas.i ng the 410℃ thermal limit, which makes.the whole proces. CMOs.compatible. Overall, our res.lts.s.gges. a new method for s.rface preparation and a pos.ible tuning of the growth mechanis. us.ng different s.rface termi nations.

关键词： Ⅲ-Ⅴ s.miconductors on s.licon InAs nanowires s.lf-catalyzed growth hydrogen preparation growth modeling dens.ty functional theory (DFT) modeling