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Sliding behaviors of the trapezoidal roof rock block under a lateral dynamic disturbance

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第3期16卷 741-760页

作者： feng dai Wancheng Zhu Min Ren Shunchuan Wu Leilei Niu Faculty of Land Resources Engineering Kunming University of Science and TechnologyKunming650093China Center for Rock Instability and Seismicity Research Department of Mining EngineeringSchool of Resource and Civil EngineeringNortheastern UniversityShenyang110819China

The surrounding rock of underground space is always affected by external dynamic disturbance from the side position,such as blasting vibration from a stope at the same level or seismic waves from adjacent strata.A series of laboratory tests,numerical simulations and theoretical analyses were carried out in this study to disclose the sliding mechanism of roof rock blocks under lateral ***,the experiments on trapezoidal key block under various clamping loads and disturbance were conducted,followed by numerical simulations using the fast Lagrangian analysis of continua(FLAC3D).Then,based on the conventional wave propagation model and the classical shear-slip constitutive model,a theoretical model was proposed to capture the relative displacement between blocks and the sliding displacement of the key *** results indicate that the sliding displacement of the key block increased linearly with the disturbance energy and decreased exponentially with the clamping load when the key block was disturbed to slide(without instability).Meanwhile,when the key block was disturbed to fall,two types of instability process may appear as immediate type or delayed *** addition,the propagation of stress waves in the block system exhibited obvious low-velocity and lowfrequency characteristics,resulting in the friction reduction effect appearing at the contact interface,which is the essential reason for the sliding of rock *** results can be applied to practical underground engineering and provide valuable guidance for the early detection and prevention of rockfalling disasters.

关键词： Lateral dynamic disturbance Trapezoidal rock block system Low-velocity and low-frequency wave Friction reduction effect Instability mode

Fangji Fuling Decoction Alleviates Sepsis by Blocking MAPK14/FOXO3A Signaling Pathway

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Chinese Journal of Integrative Medicine 2024年第3期30卷 230-242页

作者： WANG Yi CHEN Ming-qi dai Lin-feng ZHANG Hai-dong WANG Xing Department of Critical Care Medicine Changzhou Hospital of Traditional of Chinese Medicine Affiliated to Nanjing University of Chinese MedicineChangzhouJiangsu Province213000China Department of Critical Care Medicine Jiangsu Province Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese MedicineNanjing210029China

Objective:To examine the therapeutic effect of Fangji Fuling Decoction(FFD) on sepsis through network pharmacological analysis combined with in vitro and in vivo ***:A sepsis mouse model was constructed through intraperitoneal injection of 20 mg/kg lipopolysaccharide(LPS).RAW264.7 cells were stimulated by 250 ng/m L LPS to establish an in vitro cell *** pharmacology analysis identified the key molecular pathway associated with FFD in *** ectopic expression and depletion experiments,the effect of FFD on multiple organ damage in septic mice,as well as on cell proliferation and apoptosis in relation to the mitogen-activated protein kinase 14/Forkhead Box O 3A(MAPK14/FOXO3A) signaling pathway,was ***:FFD reduced organ damage and inflammation in LPS-induced septic mice and suppressed LPS-induced macrophage apoptosis and inflammation in vitro(P<0.05).Network pharmacology analysis showed that FFD could regulate the MAPK14/FOXO signaling pathway during *** confirmed by in vitro cell experiments,FFD inhibited the MAPK14 signaling pathway or FOXO3A expression to relieve LPS-induced macrophage apoptosis and inflammation(P<0.05).Furthermore,FFD inhibited the MAPK14/FOXO3A signaling pathway to inhibit LPS-induced macrophage apoptosis in the lung tissue of septic mice(P<0.05).Conclusion:FFD could ameliorate the LPS-induced inflammatory response in septic mice by inhibiting the MAPK14/FOXO3A signaling pathway.

关键词： sepsis Fangji Fuling Decoction mitogen-activated protein kinase 14/Forkhead Box O 3A signaling pathway inflammatory response apoptosis lung injury Chinese medicine

铁磁性电极条件下T形双量子点结构中马约拉纳束缚态的解耦现象

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物理学报 2024年第5期73卷 304-315页

作者：代雪峰贡同东北大学理学院沈阳110819

通过将马约拉纳束缚态侧耦合到主通道中的量子点,从理论上研究了T形双量子点体系的输运性质.结果表明,调整侧耦合量子点能级和量子点-马约拉纳束缚态耦合方式,可以在线性输运区观察到马约拉纳束缚态与T形双量子点解耦的现象.引入铁磁性... 详细信息

通过将马约拉纳束缚态侧耦合到主通道中的量子点,从理论上研究了T形双量子点体系的输运性质.结果表明,调整侧耦合量子点能级和量子点-马约拉纳束缚态耦合方式,可以在线性输运区观察到马约拉纳束缚态与T形双量子点解耦的现象.引入铁磁性电极后,电导平台的出现或损坏明显依赖于体系中磁场与电极极化方向的差异,而马约拉纳束缚态的解耦现象仍然稳固.本工作有助于进一步诠释T形双量子点体系中马约拉纳束缚态的解耦现象,为深入认知以及探测马约拉纳束缚态提供理论支持.

关键词： Andreev反射马约拉纳束缚态量子点解耦

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A seismic elastic moduli module for the measurements of low-frequency wave dispersion and attenuation of fluid-saturated rocks under different pressures

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Petroleum Science 2024年第1期21卷 162-181页

作者： Yan-Xiao He Shang-Xu Wang Gen-Yang Tang Chao Sun Hong-Bing Li San-Yi Yuan Xian Wei Li-Deng Gan Xiao-feng dai Qiang Ge Peng-Peng Wei Hui-Qing Zhang National Key Laboratory of Petroleum Resources and Engineering CNPC Key Lab of Geophysical ExplorationCollege of GeophysicsChina University of Petroleum(Beijing)Beijing102249China School of Resources and Geosciences China University of Mining and TechnologyXuzhou221116JiangsuChina Research Institute of Petroleum Exploration and Development CNPCBeijing100083China Beijing Vocational College of Labour and Social Security Beijing100029China PetroChina Dagang Oilfield Exploration and Development Research Institute CNPCTianjin300280China

Knowledge about the seismic elastic modulus dispersion,and associated attenuation,in fluid-saturated rocks is essential for better interpretation of seismic observations taken as part of hydrocarbon identification and time-lapse seismic surveillance of both conventional and unconventional reservoir and overburden performances.A Seismic Elastic Moduli Module has been developed,based on the forced-oscillations method,to experimentally investigate the frequency dependence of Young's modulus and Poisson's ratio,as well as the inferred attenuation,of cylindrical samples under different confining pressure *** with three standard samples showed that the measured elastic moduli were consistent with the published data,indicating that the new apparatus can operate reliably over a wide frequency range of f∈[1-2000,10^(6)]*** Young's modulus and Poisson's ratio of the shale and the tight sandstone samples were measured under axial stress oscillations to assess the frequency-and pressure-dependent *** dry condition,both samples appear to be nearly frequency independent,with weak pressure dependence for the shale and significant pressure dependence for the *** particular,it was found that the tight sandstone with complex pore microstructure exhibited apparent dispersion and attenuation under brine or glycerin saturation conditions,the levels of which were strongly influenced by the increased effective *** addition,the measured Young's moduli results were compared with the theoretical predictions from a scaled poroelastic model with a reasonably good agreement,revealing that the combined fluid flow mechanisms at both mesoscopic and microscopic scales possibly responsible for the measured dispersion.

关键词： Low-frequency measurements Dispersion and attenuation Rock physics Fluid flow

钢铁企业除尘用涤纶滤料在复杂烟气环境下的老化行为分析

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东北大学学报（自然科学版） 2024年第6期45卷 883-889页

作者：代峰柳静献东北大学资源与土木工程学院辽宁沈阳110819

为研究高温烟气中酸碱耦合作用对滤料性能的影响,在3种不同温度(45,75和130℃)下对涤纶滤料进行酸碱交互老化试验.发现涤纶滤料在高温酸碱耦合环境下的耐水解性能较差,且先受到碱再受到酸腐蚀对滤料产生巨大影响.在130℃下,经碱性环境... 详细信息

为研究高温烟气中酸碱耦合作用对滤料性能的影响,在3种不同温度(45,75和130℃)下对涤纶滤料进行酸碱交互老化试验.发现涤纶滤料在高温酸碱耦合环境下的耐水解性能较差,且先受到碱再受到酸腐蚀对滤料产生巨大影响.在130℃下,经碱性环境和酸性环境的交互老化后,滤料的拉伸断裂强力和面层剥离强力分别为由1638.8,143.1 N下降到1100.8,19.1 N,FT-IR(Fourier transform infrared spectroscopy)显示,C-O吸收峰减弱,表明水解过程中的聚对苯二甲酸乙二醇大分子链断裂,这也是发生水解和性能下降的主要原因.

关键词：涤纶针刺毡钢铁行业废气高温酸碱交互机械性能表面形貌化学结构

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东北全面振兴的关键:融入全国统一大市场

经济纵横 2024年第5期 79-86页

作者：戴枫刘志彪南京大学商学院江苏南京210008

融入全国统一大市场是新一轮东北全面振兴的关键,其中解决对内开放不足问题是东北融入全国统一大市场的重点。当前,推动东北全面振兴面临新的重大机遇,东北要以对内开放为抓手,以构建新发展格局为契机,重塑产业竞争优势。在宏观层面,建... 详细信息

融入全国统一大市场是新一轮东北全面振兴的关键,其中解决对内开放不足问题是东北融入全国统一大市场的重点。当前,推动东北全面振兴面临新的重大机遇,东北要以对内开放为抓手,以构建新发展格局为契机,重塑产业竞争优势。在宏观层面,建立区域协调机制,搭建东北地区一体化平台;在中观层面,整合区内价值链,打造跨区域产业联动系统;在微观层面,加大对民营企业发展的支持力度,提升资源要素的流动性和竞争性。通过深入推进对内开放,实现与全国统一大市场的有效对接,在充分的经济循环中实现东北的全面振兴。

关键词：东北振兴全国统一大市场对内开放市场化

以建设全国统一大市场增强国内外大循环的动力和活力

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金融市场研究 2024年第6期 72-81页

作者：戴枫南京林业大学经济管理学院

构建新发展格局,迫切需要加快建设高效规范、公平竞争、充分开放的全国统一大市场,建立全国统一的市场制度规则,促进商品要素资源在更大范围内畅通流动。目前,打造统一的要素和资源市场是全国统一大市场建设的关键。在要素和资源市场中... 详细信息

构建新发展格局,迫切需要加快建设高效规范、公平竞争、充分开放的全国统一大市场,建立全国统一的市场制度规则,促进商品要素资源在更大范围内畅通流动。目前,打造统一的要素和资源市场是全国统一大市场建设的关键。在要素和资源市场中,技术和数据市场的建设和完善应该先行。在市场基础制度与规则建设中,建立和完善与国际接轨的知识产权保护制度应该是眼下的重点制度建设领域。

关键词：全国统一大市场内循环外循环动力

基于3种新型群体智能算法优化正则化极限学习机的三峡水库入库日径流预测

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长江科学院院报 2024年第7期41卷 16-24页

作者：张代凤崔东文云南省文山州水利电力勘察设计院云南文山663000 云南省文山州水务局云南文山663000

准确预测的入库日径流在水库优化调度中发挥着重要作用。为提高预测精度,提出一种基于小波包变换(WPT)和蜣螂优化(DBO)算法、珍鲹优化(GTO)算法、泥环算法(MRA)优化正则化极限学习机(RELM)的预测模型,并将其应用于三峡水库入库日径流预... 详细信息

准确预测的入库日径流在水库优化调度中发挥着重要作用。为提高预测精度,提出一种基于小波包变换(WPT)和蜣螂优化(DBO)算法、珍鲹优化(GTO)算法、泥环算法(MRA)优化正则化极限学习机(RELM)的预测模型,并将其应用于三峡水库入库日径流预测研究。首先,利用WPT将三峡水库入库日径流时间序列分解为1个周期项分量和1个波动项分量;其次,利用DBO、GTO、MRA分别优化RELM输入层权值和隐含层偏差,建立WPT-DBO-RELM、WPT-GTO-RELM、WPT-MRA-RELM模型;最后,利用所建立的3种模型分别对入库日径流周期项分量和波动项分量进行预测和重构,并构建基于极限学习机(ELM)的WPT-DBO-ELM、WPT-GTO-ELM、WPT-MRA-ELM模型、基于BP神经网络的WPT-DBO-BP、WPT-GTO-BP、WPT-MRA-BP模型、未经优化的WPT-RELM、WPT-ELM、WPT-BP模型和未经分解的DBO-RELM、GTO-RELM、MRA-RELM模型作对比分析模型。结果表明:①WPT-DBO-RELM、WPT-GTO-RELM、WPT-MRA-RELM模型对三峡水库入库日径流预测的平均绝对百分比误差MAPE分别为0.512%、0.519%、0.762%,平均绝对误差MAE分别为54.05、55.97、86.76 m^(3)/s,均方根误差RMSE分别为84.99、84.81、128.18 m^(3)/s,决定系数DC≥0.9994,希尔不等系数TIC≤0.00517,预测效果优于其他12种模型,具有更高的预测精度和更好的泛化能力。②DBO、GTO、MRA能有效优化RELM网络参数,显著提高RELM预测性能。③引入正则化项的RELM可有效防止预测模型过拟合,提高模型的泛化能力,预测性能优于ELM、BP网络。④所构建的3种模型预测精度高、计算规模小,是一种有效的入库日径流时间序列预测模型。

关键词：日径流预测正则化极限学习机蜣螂优化算法珍鲹优化算法泥环算法小波包变换三峡水库

基于“互联网+智慧医疗”的医疗信息化平台的构建探索

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计算机应用文摘 2024年第8期40卷 75-77,81页

作者：代丰烟台市烟台山医院山东烟台264008

随着经济快速增长和技术进步,“互联网+”技术在医疗领域得到广泛应用,为传统医疗行业开辟了新的发展路径。文章对基于“互联网+智慧医疗”的医疗信息化平台进行了深入探索。首先,从智能化技术的角度分析了医院信息化建设,包括智慧医疗... 详细信息

随着经济快速增长和技术进步,“互联网+”技术在医疗领域得到广泛应用,为传统医疗行业开辟了新的发展路径。文章对基于“互联网+智慧医疗”的医疗信息化平台进行了深入探索。首先,从智能化技术的角度分析了医院信息化建设,包括智慧医疗案例分析、物联网在医疗信息化平台中的应用以及医疗信息化平台建设面临的挑战。其次,详细介绍了基于“互联网+智慧医疗”的医疗信息化平台的总体框架,包括医疗信息化平台的业务架构与流程优化以及技术支撑和安全保障。最后,探讨了基于“互联网+智慧医疗”的医疗信息化平台应用,涉及网上诊疗、医患服务和数据驱动的医疗决策与管理。研究结果表明,借助先进的信息技术和互联网手段,可以有效提高医疗服务的质量和效率,为实现智慧医疗提供了有力支撑。

关键词：互联网+ 智慧医疗医院信息化物联网业务架构数据驱动医疗决策