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Opto-Electronic Advances 2022年第4期5卷 48-68页

作者： Alexey wolf Alexander dostovalov Kirill Bronnikov Mikhail Skvortsov Stefan Wabnitz Sergey Babin Novosibirsk State University Novosibirsk 630090Russia Institute of Automation and Electrometry of the SB RAS Novosibirsk 630090Russia department of Information Electronics and Telecommunications EngineeringSapienza University of RomeRome 00184Italy

In this article,we review recent advances in the technology of writing fiber Bragg gratings(FBGs)in selected cores of multicore fibers(MCFs)by using femtosecond laser *** writing technology of such a key element as the FBG opens up wide opportunities for the creation of next generation fiber lasers and sensors based on *** advantages of the technology are shown by using the examples of 3d shape sensors,acoustic emission sensors with spatially multiplexed channels,as well as multicore fiber Raman lasers.

关键词： multicore fiber fiber Bragg grating femtosecond laser micromachining fiber laser fiber sensor

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Albrecht dürer

Albrecht Dürer

Three-dimensional analysis of the physiological foramen geometry of maxillary and mandibular molars by means of micro-CT

作者： (author..1949-)wolf Norbert (1471-1528.)dürer Albrecht

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International Journal of Oral Science 2017年第3期9卷 151-157页

作者： Thomas Gerhard.wolf Frank Paqué Michael Sven Patyna Brita Willershausen Benjamín Briseno-Marroquín department of Operative dentistry University Medical Center of the Johannes Gutenberg University Mainz department of Endodontology Division of Preventive DentistryPeriodontologyand CariologyCenter of Dental MedicineUniversity of Zürich

The aim of this study was to investigate the physiological foramen diameter, shape and distance between physiological and anatomical apex of maxillary and mandibular first and second molars. Accurate knowledge of the physiological foramina morphology; thus, inherent mechanical shaping technical hindrances, is decisive when taking the corresponding root canal final preparation decision. The morphological dimensions of a total of 1 727 physiological foramina were investigated by means of micro-computed tomography. Mean narrow and wide （to a high number, oval） diameters of the physiological foramen were 0.24, 0.22 and 0.33 mm and 0.33, 0.31 and 0.42 mm in mesiobuccal （MB）, distobuccal （dB） and palatal （P） roots in maxillary first molars; 0.24, 0.22 and 0.33 mm and 0.41, 0.33 and 0.44 in MB, dB, and P roots in maxillary second molars. Mandibular first molars showed mean narrow and wide diameters of 0.24 and 0.30 mm and of 0.39 and 0.46 mm in mesial （M） and distal （d） roots; second mandibular molars showed 0.25 and 0.31 mm and 0.47 mm in M and d roots. The mean distance between the physiological foramina and anatomical apex was 0.82, 0.81 and 1.02 mm and 0.54, 0.43 and 0.63 mm in MB, dB and P roots of the maxillary first and second molars, respectively. A mean distance of 0.95 mm （M） and 1.05 mm （d） in the first and 0.78 mm （M） and 0.81 mm （d） in the second mandibular molars was observed. Based on the results obtained, assumable recommendations for final preparation size of the physiological foramen were calculated. However, when taking into consideration, the resulting standard deviations of marginal errors must be cautiously considered when taking a final decision in clinical endodontic treatment.

关键词： apical constriction final apical file maxillary and mandibular molars morphology micro-computed tomography physiological foramen

Root canal morphology and configuration of 123 maxillary second molars by means of micro-CT

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International Journal of Oral Science 2017年第1期9卷 33-37页

作者： Thomas Gerhard.wolf Frank Paqué Anja-Christin Woop Brita Willershausen Benjamín Briseno-Marroquín department of Operative dentistry Johannes Gutenberg University Medical CenterMainzGermany division of Endodontology Department of Preventive DentistryPeriodontology and CariologyUniversity of ZurichZurichSwitzerland

The aim of this study was to investigate the root canal configuration, accessory canals and number of main foramina of 123 maxillary second molars by means of micro-computed tomography. The teeth were scanned and reproduced with 3d software imaging. The root canal configuration and number of main foramina were evaluated by means of a four-digit system. The morphological complexity of human maxillary second molars is depicted by the number of accessory and connecting canals. The most frequently observed root canal configurations in the mesiobuccal root were 2-2-2/2 （19.5%）, 2-2-1/1 （14.6%） and 2-1-1/1 （13.0%）. A 1-1-1/1 configuration was observed in 93.5% and in 96.7% in the distobuccal and palatal roots, respectively. The MB1 mot canal had one accessory canal （18.7%）, and 8.9% of the MB2 root canal had one or two accessory canals. The distobuccal （11.3%） and palatal （14.6%） root canals had at least one accessory canal, and connecting canals were observed in 16.3% of mesiobuccal roots. The MB1, MB2, distobuccal and palatal root canals had one main foramen in 99.2%, 43.1%, 98.4% and 99.2% of samples, respectively. In the mesiobuccal root, one accessory foramen was detected in 14.6%, two were detected in 7.3%, and three were detected in 5.7%. The distobuccal root showed one or two accessory foramina in 9.1% of samples. The root canal configuration of maxillary second molars is quite heterogeneous; the mesiobuccal root has predominantly two root canal entrances （58.4%, 1 in 41.1%） with one main foramen （54.4%）. Two main foramina were observed in 43.0%. Morphological variations, connecting and accessory canals were observed in all apical thirds.

关键词： accessory and connecting canals apical foramina maxillary second molar micro-CT morphology root canal configuration

Value of three-dimensional reconstructions in pancreatic carcinoma using multidetector CT:Initial results

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World Journal of Gastroenterology 2009年第46期15卷 5827-5832页

作者： Miriam Klauβ Max Schbinger Ivo wolf Jens Werner Hans-Peter Meinzer Hans-Ulrich Kauczor Lars Grenacher department of diagnostic and Interventional Radiology University of Heidelberg department of Medical and Biological Informatics German Cancer Research Center(DKFZ) Surgical Clinic University of Heidelberg

AIM:To evaluate the use of three-dimensional imaging of pancreatic carcinoma using multidetector computed tomography(CT)in a prospective ***:Ten patients with suspected pancreatic tumors were examined prospectively using multidetec-tor CT(Somatom Sensation 16,Siemens,Erlangen,Germany).The images were evaluated for the pres-ence of a pancreatic carcinoma and invasion of the peripancreatic vessels and surrounding *** the isotropic CT data sets,a three-dimensional image was created with automatic vascular analysis and semi-automatic segmentation of the organs and pancreatic tumor by a *** CT examinations and the three-dimensional images were presented to the sur-geon directly before and during the patient's operation using the Medical Imaging Interaction Toolkit-based software "ReLiver".Immediately after surgery,the value of the two images was judged by the *** operation and the histological results served as the gold ***:Nine patients had a pancreatic carcinoma(all pT3),and one patient had a serous *** tumor inf iltrated the superior mesenteric *** inf iltration was correctly *** carcinomas were *** comparison to the CT image with axial and coronal reconstructions,the three-dimensional image was judged by the surgeons as better for operation planning and consistently described as ***:A 3d-image of the pancreas repre-sents an invaluable aid to the ***,the 3d-software must be further developed in order to be integrated into daily clinical routine.

关键词： Pancreatic carcinoma 3d-reconstruction Multidetector computed tomography Pancreatic carcinomainvasion Segmentation

Liver biochemistry profile,significance and endoscopic management of biliary tract complications post orthotopic liver transplantation

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World Journal of Gastroenterology 2007年第20期13卷 2819-2825页

作者： Yogesh M Shastri Nicolas M Hoepffner Bora Akoglu Christina Zapletal wolf O Bechstein wolfgang F Caspary dominik Faust department of Medicine I J.W. Goethe-University HospitalTheodor-Stern-Kai 7D -60590 Frankfurt am MainGermany department of Surgery Theodor-Stern-Kai 7D-60590J.W. Goethe University HospitalFrankfurt am MainGermany

AIM： To correlate the significance of liver biochemical tests in diagnosing post orthotopic liver transplantation （OLT） biliary complications and to study their profile before and after endoscopic therapy.METHOdS： Patients who developed biliary complications were analysed in detail for the clinical information, laboratory tests, treatment offered, response to it, follow up and outcomes. The profile of liver enzymes was determined. The safety, efficacy and outcomes of endoscopic retrograde cholangiography （ERC） were also analysed. RESULTS： 40 patients required ERC for 70 biliary complications. GGT was found to be 〉 3 times （388.1 ± 70.9 U/mL vs 168.5 4± 34.2 U/L, P = 0.007） and SAP 〉 2 times （345.1 ± 59.1 U/L vs 152.7 ± 21.4 U/L, P = 0.003） the immediate post OLT values. Most frequent complication was isolated anastomotic res in 28 （40%）. Sustained success was achieved in 26 （81%） patients. CONCLUSION： Biliary complications still remain an important problem post OLT. SAP and GGT can be used as early, non-invasive markers for diagnosis and also to assess the adequacy of therapy. Endoscopic management is usually effective in treating the majority of these biliary complications.

关键词： Liver biochemistry Biliary lesion Ischemic type biliary lesions Endoscopic therapy Orthotopic liver transplantation

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柳枝稷种子休眠的回复与破除

种子 1997年第1期16卷 57-59页

作者：谢正苗 d.J.Parrish d.d.wolf 浙江农业大学环境与资源学院 VPI&SU.Virginia24061.USA

本文提出了经湿润冷冻层化处理后的柳枝稷种子再干燥后的休眠回复现象,探讨了氧气浓度、高温贮藏，干湿交替对休眠回复的影响。在湿润冷冻层化过程中。3次干湿交替处理可克服休眠回复．使发芽率达到85％以上。

关键词：柳枝稷种子休眠回复破除

Vertical-cavity surface-emitting lasers for data communication and sensing

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Photonics Research 2019年第2期7卷 121-136页

作者： ANJIN LIU PHILIP wolf JAMES A.LOTT dIETER BIMBERG Laboratory of Solid-State Optoelectronics Information Technology Institute of SemiconductorsChinese Academy of Sciences State Key Laboratory on Integrated Optoelectronics Institute of SemiconductorsChinese Academy of Sciences Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of Sciences Institute of Solid State Physics and Center of Nanophotonics Technische Universitat Berlin Bimberg Chinese-German Center for Green Photonics of the Chinese Academy of Sciences at CIOMP

Vertical-cavity surface-emitting lasers(VCSELs) are the ideal optical sources for data communication and *** data communication, large data rates combined with excellent energy efficiency and temperature stability have been achieved based on advanced device design and modulation formats. VCSELs are also promising sources for photonic integrated circuits due to their small footprint and low power consumption. Also, VCSELs are commonly used for a wide variety of applications in the consumer electronics market. These applications range from laser mice to three-dimensional(3 d) sensing and imaging, including various 3 d movement detections, such as gesture recognition or face recognition. Novel VCSEL types will include metastructures, exhibiting additional unique properties, of largest importance for next-generation data communication, sensing, and photonic integrated circuits.

关键词： Vertical-cavity surface-emitting communication

Sodium alendronate loaded poly(L-lactideco-glycolide)microparticles immobilized on ceramic scaffolds for local treatment of bone defects

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Regenerative Biomaterials 2020年第3期7卷 293-302页

作者： Lucja Rumian Cornelia wolf-Brandstetter Sina Roβler Katarzyna Reczynska Hanna Tiainen Havard J.Haugen dieter Scharnweber Elzbieta Pamula Faculty of Materials Science and Ceramics Department of Biomaterials and CompositesAGH University of Science and TechnologyAl.A.Mickiewicza 30Krakow 30-059Poland Technische Universitat dresden Institute of Materials ScienceMax Bergmann Center of BiomaterialsBudapester Str.27Dresden 01-069Germany department of Biomaterials Institute for Clinical DentistryUniversity of OsloGeitmyrsveien 71BlindernP.O.Box 1109Oslo NO-0317Norway

Bone tissue regeneration in critical-size defects is possible after implantation of a 3d scaffold and can be additionally enhanced once the scaffold is enriched with drugs or other factors supporting bone remodelling and *** alendronate(Aln),a widely used anti-osteoporosis drug,exhibits strong inhibitory effect on bone resorption performed by ***,we propose a new approach for the treatment of bone defects in craniofacial region combining biocompatible titanium dioxide scaffolds and poly(L-lactide-co-glycolide)microparticles(MPs)loaded with *** MPs were effectively attached to the surface of the scaffolds’pore walls by human recombinant *** release from the scaffolds was characterized by initial burst(2466% of the drug released within first 24 h)followed by a sustained release phase(on average 5 mg of Aln released per day from day 3 to day 18).In vitro tests evidenced that Aln at concentrations of 5 and 2.5 mg/ml was not cytotoxic for MG-63 osteoblast-like cells(viability between 8166% and 9863% of control),but it prevented RANKL-induced formation of osteoclast-like cells from macrophages derived from peripheral blood mononuclear cells,as shown by reduced fusion capability and decreased tartrateresistant acid phosphatase 5b activity(5665% reduction in comparison to control after 8 days of culture).Results show that it is feasible to design the scaffolds providing required doses of Aln inhibiting osteoclastogenesis,reducing osteoclast activity,but not affecting osteoblast functions,which may be beneficial in the treatment of critical-size bone tissue defects.

关键词： ceramic scaffolds sodium alendronate osteoblasts osteoclastogenesis collagen critical-size defect poly(L-lactideco-glycolide) microparticles

大花罗布麻对MPTP型小鼠的多巴胺能神经保护作用研究

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中国药理学通报 2010年第3期26卷 397-400页

作者：马成马龙 RAUSCH wolf-dieter 新疆医科大学公共卫生学院新疆医科大学药学院新疆乌鲁木齐830054 维也纳兽医大学神经化学研究所

目的观察大花罗布麻叶中槲皮素-3-O-槐糖苷和黄酮富集物对MPTP型帕金森症(Parkinson's disease,Pd)小鼠模型的多巴胺能(dopaminergic,dA)神经保护作用。方法以C57/bl6小鼠为研究对象,采用MPTP腹腔注射***-1连续5d制备Pd模型,口服灌胃给... 详细信息

目的观察大花罗布麻叶中槲皮素-3-O-槐糖苷和黄酮富集物对MPTP型帕金森症(Parkinson's disease,Pd)小鼠模型的多巴胺能(dopaminergic,dA)神经保护作用。方法以C57/bl6小鼠为研究对象,采用MPTP腹腔注射***-1连续5d制备Pd模型,口服灌胃给予槲皮素-3-O-槐糖苷***-1和大花罗布麻叶黄酮富集物***-1,造模前7d开始给药。给药结束后进行自主活动和爬杆实验测试动物行为变化,荧光法测定纹状体中多巴胺含量,石蜡切片观察黑质神经细胞病理变化,分析大花罗布麻对多巴胺能神经的保护作用。结果槲皮素-3-O-槐糖苷***-1预先给药1wk,能提升MPTP型Pd小鼠的运动能力,提高纹状体中多巴胺含量,减轻黑质神经的损伤,增加酪氨酸羟化酶(tyrosine hydroxylase,TH)阳性细胞表达数量。结论槲皮素-3-O-槐糖苷能减轻MPTP对Pd小鼠的dA神经损伤。

关键词：大花罗布麻槲皮素-3-O-槐糖苷 MPTP Pd模型酪氨酸羟化酶多巴胺能神经保护