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Impact of pre- and peri-operative risk factors on length of stay and hospital readmission following minimally-invasive partial nephrectomy

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Asian Journal of Urology 2024年第1期11卷 72-79页

作者： Vanessa A.Lukas Rahul dutta Ashok K.Hemal Matvey Tsivian Timothy e.Craven Nicholas A.deebel david d.Thiel Ram Anil Pathak Brigham and Women's Hospital Division of UrologyDepartment of Surgery75 Francis StreetBostonMAUSA Atrium Health Wake Forest Baptist Medical Center Department of Urology1 Medical Center BlvdWinston-SalemNCUSA Mayo Clinic Florida Department of Urology4500 San Pablo RoadJacksonvilleFLUSA

Objective:We conducted an analysis of the American College of Surgeons National Surgical Quality Improvement Program database for minimally-invasive partial nephrectomy cases reported with the goal to identify pre-and peri-operative variables associated with length of stay(LOS)greater than 3 days and readmission within 30 ***:Records from 2008 to 2018 for“laparoscopy,surgical;partial nephrectomy”for prolonged LOS and readmission cohorts were *** analysis with Chi-square,t-tests,and multivariable logistic regression analysis with odds ratios(ORs),p-values,and 95%confidence intervals assessed statistical ***:Totally,20306 records for LOS greater than 3 days and 15854 for readmission within 30 days were *** and multivariable analysis exhibited similar *** LOS greater than 3 days,undergoing non-elective surgery(OR=5.247),transfusion of greater than four units within 72 h prior to surgery(OR=5.072),pre-operative renal failure or dialysis(OR=2.941),and poor pre-operative functional status(OR=2.540)exhibited the strongest statistically significant *** hospital readmission within 30 days,loss in body weight greater than 10%in 6 months prior to surgery(OR=2.227)and bleeding disorders(OR=2.081)exhibited strongest statistically significant ***:Multiple pre-and peri-operative risk factors are independently associated with prolonged LOS and hospital readmission within 30 days of surgery using the American College of Surgeons National Surgical Quality Improvement Program *** the risks factors that can potentially be improved prior to minimally-invasive partial nephrectomy is crucial to informing patient selection,optimization strategies,and patient education.

关键词： Minimally-invasive partial nephrectomy The American College of Surgeons National Surgical Quality Improvement Program Lengthof stay Hospital readmission

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Pelvic fractures in blunt trauma patients:A comparative study

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World Journal of Orthopedics 2024年第5期15卷 418-434页

作者： Alexander A Fokin Joanna Wycech Knight Madison e Tharp Kyler C Brinton Phoebe K Gallagher Justin Fengyuan Xie Russell d Weisz Ivan Puente Trauma and Critical Care Services Delray Medical CenterDelray BeachFL 33484United States Charles e Schmidt College of Medicine Department of SurgeryFlorida Atlantic UniversityBoca RatonFL 33431United States Trauma and Critical Care Services Broward Health Medical CenterFort LauderdaleFL 33316United States Charles e Schmidt College of Medicine Florida Atlantic UniversityBoca RatonFL 33431United States Herbert Wertheim College of Medicine Department of SurgeryFlorida International UniversityMiamiFL 33199United States

BACKGROUNd Pelvic fractures(PF)with concomitant injuries are on the rise due to an increase of high-energy *** of the elderly population with age related comorbidities further complicates the *** organ injuries are kindred with PF due to the proximity to pelvic *** of contrast blush(CB)on computed tomography in patients with PF is considered a sign of active bleeding,however,its clinical significance and association with outcomes is *** To analyze polytrauma patients with PF with a focus on the geriatric population,co-injuries and the value of contrast *** This retrospective cohort study included 558 patients with PF admitted to level 1 trauma center(01/2017-01/2023).Analyzed variables included:Age,sex,mechanism of injury(MOI),injury severity score(ISS),Glasgow coma scale(GCS),abbreviated injury scale(AIS),co-injuries,transfusion requirements,pelvic angiography,embolization,laparotomy,orthopedic pelvic surgery,intensive care unit and hospital lengths of stay,discharge disposition and *** study compared geriatric and non-geriatric patients,patients with and without CB and abdominal *** score matching was implemented in comparison *** PF comprised 4%of all trauma admissions.89 patients had CB.286(52%)patients had concomitant injuries including 93(17%)patients with abdominal *** patients compared to non-geriatric had more falls as MOI,lower ISS and AIS pelvis,higher GCS,less abdominal co-injuries,similar CB and angio-embolization rates,less orthopedic pelvic surgeries,shorter lengths of stay and higher *** propensity matching,orthopedic pelvic surgery rates remained lower(8%vs 19%,Pength of stay shorter,and mortality higher(13%vs 4%,Periatric *** of 89 patients with CB,45(51%)were *** propensity matching,patients with CB compared to without CB had more pelvic angiography(71%vs 12%,P<0.001),hi

关键词： Pelvic fractures Geriatric trauma patients Abdominal co-injuries Contrast blush Contrast extravasation Angioembolization Polytrauma patients Surgical interventions Blunt trauma external and internal fixation for pelvic stabilization

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The effects of local variations in conditions on carbon storage and release in the continental mantle

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National Science Review 2024年第6期11卷 22-36页

作者： Stephen F.Foley Chunfei Chen dorrit e.Jacob School of Natural Sciences Macquarie University Research School of earth Sciences Australian National University State Key Laboratory of Geological Processes and Mineral Resources School of Earth Sciences China University of Geosciences

Recent advances indicate that the amount of carbon released by gradual degassing from the mantle needs to be revised upwards, whereas the carbon supplied by plumes may have been overestimated in the *** in rock types and oxidation state may be very local and exert strong influences on carbon storage and release mechanisms. deep subduction may be prevented by diapirism in thick sedimentary packages,whereas carbonates in thinner sequences may be subducted. Carbonates stored in the mantle transition zone will melt when they heat up, recognized by coupled stable isotope systems(e.g. Mg, Zn, Ca). There is no single ‘mantle oxygen fugacity’, particularly in the thermal boundary layer(TBL) and lowermost lithosphere, where very local mixtures of rock types coexist. Carbonate-rich melts from either subduction or melting of the uppermost asthenosphere trap carbon by redox freezing or as carbonate-rich dykes in this zone. deeply derived, reduced melts may form further diamond reservoirs, recognized as polycrystalline diamonds associated with websteritic silicate minerals. Carbon is released by either edge-driven convection,which tears sections of the TBL and lower lithosphere down so that they melt by a mixture of heating and oxidation, or by lateral advection of solids beneath rifts. Both mechanisms operate at steps in lithosphere thickness and result in carbonate-rich melts, explaining the spatial association of craton edges and carbonate-rich magmatism. High-pressure experiments on individual rock types, and increasingly on reactions between rocks and melts, are fine-tuning our understanding of processes and turning up unexpected results that are not seen in studies of single rocks. Future research should concentrate on elucidating local variations and integrating these with the interpretation of geophysical signals. Global concepts such as average sediment compositions and a uniform mantle oxidation state are not appropriate for small-scale processes; an increa

关键词： lithospheric mantle carbonate melts deep carbon cycle craton destruction continental rifts

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evaluation of the seismic behavior of reinforced concrete structures with flat slab-column gravity frame and shear walls through nonlinear analysis methods

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earthquake engineering and engineering Vibration 2024年第3期23卷 713-726页

作者： M.A.Najafgholipour S.Heidarian Radbakhsh e.erfani department of Civil and environmental engineering Shiraz University of TechnologyShiraz ***Iran department of Building Civiland Environmental EngineeringConcordia UniversityMontréal H3G 1M8Canada

This paper presents an investigation of the seismic behavior of reinforced concrete(RC)structures in which shear walls are the main lateral load-resisting elements and the participation of flat slab floor systems is not considered in the seismic design *** this regard,the behavior of six prototype structures(with different heights and plan layouts)is investigated through nonlinear static and time history analyses,implemented in the OpenSees *** results of the analyses are presented in terms of the behavior of the slab-column connections and their mode of failure at different loading ***,the global response of the buildings is discussed in terms of some parameters,such as lateral overstrength due to the gravity flat slab-column *** to the nonlinear static analyses,in structures in which the slab-column connections were designed only for gravity loads,the slab-column connections exhibited a punching mode of failure even in the early stages of ***,the punching failure was eliminated in structures in which a minimum transverse reinforcement recommended in ACI 318(2019)was provided in the slabs at joint ***,despite neglecting the contribution of gravity flat slab-column frames in the lateral load resistance of the structures,a relatively significant overstrength was imposed on the structures by the gravity frames.

关键词： RC flat slab-column frames seismic behavior nonlinear analysis time history analysis

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emission colour tuning in KLnF_(4):Yb^(3+),er^(3+)/Ho^(3+)phosphor

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Journal of Rare earths 2024年第1期42卷 57-65,I0002页

作者： Janani K Gayathri e Vijayatha V Ramasubramanian S Thiyagarajan P department of Science and Humanities Nehru Institute of TechnologyKaliapuramThirumalayampalayamCoimbatoreIndia department of Sciences Amrita School of Physical SciencesAmrita Vishwa VidyapeethamCoimbatoreIndia department of Physics Anna UniversityChennaiIndia

KLnF_(4):Yb^(3+),er^(3+)/Ho^(3+)(Ln=Y,Yb,Gd)phosphors were prepared by solid-state reaction *** each of the Yb^(3+)/er^(3+)and Yb^(3+)/Ho^(3+)co-doped phosphors independently,phase confirmation and morphological examination were accomplished using the X-ray diffraction technique and scanning electron microscope analysis.X-ray photoelectron spectroscopy analysis shows the charge state and existence of lanthanides and *** luminescence emissions of green and red colour were detected for the synthesized *** changes in the upconverted emission intensities and colour output pertaining to the change of the lanthanide host matrix along with dopants were investigated for the prepared *** the upconversion luminescence,erbium-doped samples exhibit a predominance of red emission while holmium-doped samples display a prevalence of green *** rare-earth er/Ho doped KYbF4shows strong red emission compared to other ***_(4):Yb,er/Ho exhibits relatively significant green upconve rsion emissions,while Yb,er-doped KGdF_(4)host displays a 10-fold increase in green/red emission ratio with an increase in the input power of 20-780 *** photoluminescence studies and decay curve analysis were carried out using UV light excitation for the developed phosphors.A higher lifetime of 2.2 ms was measured for the downshifting red emission in the Ho doped KYbF_(4)*** study suggests a potential for colour tunability in the upconversion and downshifting emissions through host modifications to the fluoride phosphor.

关键词： Rare earths energy transfer upconversion downshifting Colour coordinates

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A new method for precise optical measurements of the sub-micron height of levitation of droplet clusters

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Particuology 2024年第4期87卷 173-178页

作者： Alexander A.Fedorets eduard e.Kolmakov Leonid A.dombrovsky University of Tyumen 6 Volodarskogo StTyumen625003Russia engineering Faculty Ariel UniversityP0.B.3407000ArielIsrael Joint Institute for High Temperatures 17A Krasnokazarmennaya StMoscow111116Russia

droplet clusters levitating over the locally heated water surface are considered a very promising phe-nomenon of microfluidics for the potential use of the droplets as unique microreactors for microbio-logical experiments.A new optical method is suggested for precise measurements of the sub-micron levitation height of single *** method is based on the analysis of variable colors of the inter-ference halo around the *** the first time,it is possible to measure the extremely low downward velocity of droplets,which grow due to steam *** velocity was found to be 5-8 nm/*** height of the levitation of various droplets just before their coalescence with a layer of water was also *** measurements might be used for the verification of sophisticated models for the droplet levitation to be developed for a very thin layer of humid air under the droplet when the Knudsen effect should be taken into account.

关键词： Precise measurements Interferometric method droplet cluster Levitation height

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Carbene chemistry for unnatural biosynthesis

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Science China(Life Sciences) 2024年第1期67卷 204-207页

作者： Jing Huang Jay d.Keasling department of Chemical and Biomolecular engineering University of CaliforniaBerkeley 94720USA Joint Bioenergy Institute Lawrence Berkeley National LaboratoryEmeryville 94608USA Biological Systems and engineering division Lawrence Berkeley National LaboratoryBerkeley 94720USA Novo Nordisk Foundation Center for Biosustainability Technical University of DenmarkKongens Lyngby 2800Denmark department of Bioengineering University of CaliforniaBerkeley 94720USA Synthetic Biochemistry Center Institute for Synthetic BiologyShenzhen Institutes for Advanced TechnologiesShenzhen 518055China

Previously,chemists working in synthesis were jealous of biologists since the enzymes found in nature usually exhibited great catalytic properties(e.g.,high catalytic efficiency,excellent selectivity such as substrate selectivity,regioselectivity and stereoselectivity).However,biological systems lack many counterparts of reactions widely used in chemical synthesis.

关键词： synthesis selectivity catalytic

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Numerical calculation of Z-scan measurements for nonlinear media with large phase shift

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Optoelectronics Letters 2024年第3期20卷 177-182页

作者： M.d.Zidan A.Allahham department of Physics Atomic Energy Commission of SyriaP.O.Box 6091DamascusSyria

We have reported the characteristics of a Z-scan for the poly(azaneylylidene-acylene)(dAZA) polymer, as nonlinear medium with a large nonlinear phase shift using continuous-wave(CW) laser beam. It has been verified that the Fresnel diffraction model is applicable for analyses of Z-scan measurements with dAZA polymer at high laser power. It was found that Z-scan curves with peak-to-valley features appear as the applied light intensity increases in the case of a large nonlinear phase shift. The Z-scan experiments were carried out using a CW laser to verify the theoretical calculations in the case of a large nonlinear phase shift model. Our results show good agreements between the experimental data and the proposed theoretical models.

关键词： nonlinear phase media

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Ion heat transport in electron cyclotron resonance heated L-mode plasma on the T-10 tokamak

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Plasma Science and Technology 2024年第4期26卷 52-60页

作者： V.A.KRUPIN M.R.NURGALIeV A.R.NeMeTS I.A.ZeMTSOV S.d.SUNTSOV T.B.MYALTON d.S.SeRGeeV N.A.SOLOVeV d.V.SARYCHeV d.V.RYJAKOV S.N.TUGARINOV N.N.NAUMeNKO National Research Centre“Kurchatov Institute” Moscow 123182Russia Bauman Moscow State Technical University Moscow 105005Russia Institution“Project Center ITeR” Moscow 123098Russia JSC“SOLAR” Minsk 220034Belarus

Anomalous ion heat transport is analyzed in the T-10 tokamak plasma heated with electron cyclotron resonance heating(eCRH) in second-harmonic extra-ordinary mode. Predictive modeling with empirical scaling for Ohmical heat conductivity shows that in eCRH plasmas the calculated ion temperature could be overestimated, so an increase of anomalous ion heat transport is required. To study this effect two scans are presented: over the eC resonance position and over the eCRH power. The eC resonance position varies from the high-field side to the low-field side by variation of the toroidal magnetic field. The scan over the heating power is presented with on-axis and mixed eCRH regimes. discharges with high anomalous ion heat transport are obtained in all considered regimes. In these discharges the power balance ion heat conductivity exceeds the neoclassical level by up to 10 times. The high ion heat transport regimes are distinguished by three parameters: the ratio Te/Ti, the normalized electron density gradient R/■, and the ion–ion collisionality νii~*. The combination of high Te/Ti, high νii~*, and R/■=6-10 results in values of normalized anomalous ion heat fluxes up to 10 times higher than in the low transport scenario.

关键词： tokamak L-mode electron cyclotron resonance heating ion heat transport

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Adipose-derived regenerative therapies for the treatment of knee osteoarthritis

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World Journal of Stem Cells 2024年第4期16卷 324-333页

作者： Ilias e epanomeritakis Wasim S Khan division of Trauma and Orthopaedic Surgery Addenbrooke’s HospitalCambridge University Hospitals NHS Foundation TrustCambridge CB20QQUnited Kingdom division of Trauma and Orthopaedic Surgery Department of SurgeryUniversity of CambridgeCambridge CB20QQUnited Kingdom

Knee osteoarthritis is a degenerative condition with a significant disease burden and no disease-modifying *** treatment ultimately requires joint *** capable of regenerating cartilage could significantly reduce financial and clinical *** regenerative potential of mesenchymal stromal cells(MSCs)has been extensively studied in the context of knee *** has yielded promising results in human studies,and is likely a product of immunomodulatory and chondroprotective biomolecules produced by MSCs in response to ***-derived MSCs(ASCs)are becoming increasingly popular owing to their relative ease of isolation and high proliferative *** vascular fraction(SVF)and micro-fragmented adipose tissue(MFAT)are produced by the enzymatic and mechanical disruption of adipose tissue,*** avoids expansion of isolated ASCs ex vivo and their composition of heterogeneous cell populations,including immune cells,may potentiate the reparative function of *** this editorial,we comment on a multicenter randomized trial regarding the efficacy of MFAT in treating knee *** discuss the study’s findings in the context of emerging evidence regarding adipose-derived regenerative *** underlying mechanism of action of ASCs is proposed while drawing important distinctions between the properties of isolated ASCs,SVF,and MFAT.

关键词： Knee osteoarthritis Mesenchymal stromal cells Adipose tissue Stromal vascular fraction Micro-fragmented adipose tissue Regeneration

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