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Applied Mathematics and Mechanics(English Edition) 2017年第1期38卷 73-98页

作者： d.v.dung H.T.THIEM Faculty of Mathematics Mechanics and InformaticsVietnam National UniversityHanoi 100000Vietnam

The postbuckling of the eccentrically stiffened circular cylindrical shells made of functionally graded materials （FGMs）, subjected to the axial compressive load and external uniform pressure and filled inside by the elastic foundations in the thermal environments, is investigated with an analytical method. The shells are reinforced by FGM stringers and rings. The thermal elements of the shells and stiffeners in the fundamental equations are considered. The equilibrium and nonlinear stability equations in terms of the displacement components for the stiffened shells are derived with the third-order shear deformation theory and Leckhniskii smeared stiffener technique. The closed-form expressions for determining the buckling load and postbuckling load-deflection curves are obtained with the Galerkin method. The effects of the stiffeners, the foundations, the material and dimensional parameters, and the pre-existent axial compressive and thermal load are considered.

关键词： stiffened cylindrical shell functionally graded material (FGM) postbuck- ling elastic foundation analytical

Nonlinear analysis on dynamic buckling of eccentrically stiffened functionally graded material toroidal shell segment surrounded by elastic foundations in thermal environment and under time-dependent torsional loads

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Applied Mathematics and Mechanics(English Edition) 2016年第7期37卷 835-860页

作者： d.v.dung P.M.vUONG department of Mathematics Mechanics and InformaticsVietnam National University Faculty of Civil and Industrial National University of Civil Engineering

The nonlinear analysis with an analytical approach on dynamic torsional buckling of stiffened functionally graded thin toroidal shell segments is investigated. The shell is reinforced by inside stiffeners and surrounded by elastic foundations in a thermal environment and under a time-dependent torsional load. The governing equations are derived based on the donnell shell theory with the yon Karman geometrical nonlinearity, the Stein and McElman assumption, the smeared stiffeners technique, and the Galerkin method. A deflection function with three terms is chosen. The thermal parameters of the uniform temperature rise and nonlinear temperature conduction law are found in an explicit form. A closed-form expression for determining the static critical torsional load is obtained. A critical dynamic torsional load is found by the fourth-order Runge-Kutta method and the Budiansky-Roth criterion. The effects of stiffeners, foundations, material, and dimensional parameters on dynamic responses of shells are considered.

关键词： toroidal shell segment functionally graded material (FGM) stiffened shell,critical static and dynamic torsional load thermal environment

Nonlinear thermo-mechanical stability of eccentrically stiffened functionally graded material sandwich doubly curved shallow shells with general sigmoid law and power law according to third-order shear deformation theory

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Applied Mathematics and Mechanics(English Edition) 2017年第2期38卷 191-216页

作者： d.v.dung d.T.dONG Faculty of Mathematics Mechanics and Informatics Vietnam National University Hanoi 100000 Vietnam Faculty of Civil Engineering University of Transport Technology Hanoi 100000 Vietnam

In this paper, the nonlinear analysis of stability of functionally graded ma- terial （FGM） sandwich doubly curved shallow shells is studied under thermo-mechanical loads with material properties obeying the general sigmoid law and power law of four ma- terial models. Shells are reinforced by the FGM stiffeners and rest on elastic foundations. Theoretical formulations are derived by the third-order shear deformation theory （TSdT） with the von Karman-type nonlinearity taking into account the initial geometrical im- perfection and smeared stiffener technique. The explicit expressions for determining the critical buckling load and the post-buckling mechanical and thermal load-deflection curves are obtained by the Galerkin method. Two iterative algorithms are presented. The effects of the stiffeners, the thermal element, the distribution law of material, the initial imper- fection, the foundation, and the geometrical parameters on buckling and post-buckling of shells are investigated.

关键词： functionally graded material (FGM) sandwich double curved shallow shell,thermo-mechanical stability FGM stiffener elastic foundation

Nonlinear stability of functionally graded material(FGM)sandwich cylindrical shells reinforced by FGM stiffeners in thermal environment

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Applied Mathematics and Mechanics(English Edition) 2017年第5期38卷 647-670页

作者： d.v.dung N.T.NGA L.K.HOA Faculty of Mathematics Mechanics and InformaticsVietnam National UniversityHanoi 100000Vietnam Faculty of Basic Science Military Logistic AcademyHanoi 100000Vietnam

In this paper, donnell＇s shell theory and smeared stiffeners technique are improved to analyze the postbuckling and buckling behaviors of circular cylindrical shells of stiffened thin functionally graded material （FGM） sandwich under an axial loading on elastic foundations, and the shells are considered in a thermal environment. The shells are stiffened by FGM rings and stringers. A general sigmoid law and a general power law are proposed. Thermal elements of the shells and reinforcement stiffeners are considered. Explicit expressions to find critical loads and postbuckling load-deflection curves are obtained by applying the Galerkin method and choosing the three-term approximate solution of deflection. Numerical results show various effects of temperature, elastic foundation, stiffeners, material and geometrical properties, and the ratio between face sheet thickness and total thickness on the nonlinear behavior of shells.

关键词： functionally graded material (FGM) stiffened cylindrical shell sandwich,thermal environment

Buckling analysis of functionally graded material(FGM) sandwich truncated conical shells reinforced by FGM stiffeners filled inside by elastic foundations

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Applied Mathematics and Mechanics(English Edition) 2016年第7期37卷 879-902页

作者： d.v.dung L.K.HOA B.T.THUYET N.T.NGA Faculty of Mathematics Mechanics and Informatics Vietnam National University Faculty of Basic Science Military Logistic AcademyHanoi Faculty of Mining Hanoi University of Mining and Geology

An analytical solution for buckling of an eccentrically stiffened sandwich truncated conical shell is investigated. The shell consists of two functionally graded material （FGM） coating layers and a core layer which are metal or ceramic subjected to an axial compressive load and an external uniform pressure. Shells are reinforced by stringers and rings, in which the material properties of shells and stiffeners are graded in the thickness direction following a general sigmoid law distribution. Two models of coated shell-stiffener arrangements are investigated. The change of the spacing between stringers in the meridional direction is taken into account. A couple set of three-variable- coefficient partial differential equations in terms of displacement components are solved by the Galerkin method. A closed-form expression for determining the buckling load is obtained. The numerical examples are presented and compared with previous works.

关键词： functionally graded material (FGM) sandwich truncated conical shell,stiffener elastic foundation buckling analysis

A comprehensive investigation on nonlinear vibration and bending characteristics of bio-inspired helicoidal laminated composite structures

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 81-100页

作者： S.SAURABH R.KIRAN d.SINGH R.vAISH v.S.CHAUHAN School of Mechanical and Materials Engineering Indian Institute of Technology Mandi

Bio-inspired helicoidal composite laminates, inspired by the intricate helical structures found in nature, present a promising frontier for enhancing the mechanical properties of structural designs. Hence, this study provides a comprehensive investigation into the nonlinear free vibration and nonlinear bending behavior of bio-inspired composite plates. The inverse hyperbolic shear deformation theory(IHSdT) of plates is employed to characterize the displacement field, with the incorporation of Green-Lagrange nonlinearity. The problem is modeled using the C0finite element method(FEM), and an in-house code is developed in the MATLAB environment to solve it numerically. various helicoidal layup configurations including helicoidal recursive(HR), helicoidal exponential(HE), helicoidal semi-circular(HS), linear helicoidal(LH), and Fibonacci helicoidal(FH)with different layup sequences and quasi-isotropic configurations are studied. The model is validated, and parametric studies are conducted. These studies investigate the effects of layup configurations, side-to-thickness ratio, modulus ratios, boundary conditions, and loading conditions at different load amplitudes on the nonlinear vibration and nonlinear bending behaviors of bio-inspired composite plates. The results show that the laminate sequence exerts a substantial impact on both nonlinear natural frequencies and nonlinear bending behaviors. Moreover, this influence varies across different side-to-thickness ratios and boundary conditions of the bio-inspired composite plate.

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Semantic Segmentation of Lumbar vertebrae Using Meijering U-Net(MU-Net)on Spine Magnetic Resonance Images

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 733-757页

作者： Lakshmi S v v Shiloah Elizabeth darmanayagam Sunil Retmin Raj Cyril department of Computer Science and Engineering College of Engineering GuindyAnna UniversityChennai600025India department of Information Technology Madras Institute of TechnologyAnna UniversityChrompetChennai600044India

Lower back pain is one of the most common medical problems in the world and it is experienced by a huge percentage of people *** to its ability to produce a detailed view of the soft tissues,including the spinal cord,nerves,intervertebral discs,and vertebrae,Magnetic Resonance Imaging is thought to be the most effective method for imaging the *** semantic segmentation of vertebrae plays a major role in the diagnostic process of lumbar *** is difficult to semantically partition the vertebrae in Magnetic Resonance Images from the surrounding variety of tissues,including muscles,ligaments,and intervertebral discs.U-Net is a powerful deep-learning architecture to handle the challenges of medical image analysis tasks and achieves high segmentation *** work proposes a modified U-Net architecture namely MU-Net,consisting of the Meijering convolutional layer that incorporates the Meijering filter to perform the semantic segmentation of lumbar vertebrae L1 to L5 and sacral vertebra ***-colour mask images were generated and used as ground truth for training the *** work has been carried out on 1312 images expanded from T1-weighted mid-sagittal MRI images of 515 patients in the Lumbar Spine MRI dataset publicly available from Mendeley *** proposed MU-Net model for the semantic segmentation of the lumbar vertebrae gives better performance with 98.79%of pixel accuracy(PA),98.66%of dice similarity coefficient(dSC),97.36%of Jaccard coefficient,and 92.55%mean Intersection over Union(mean IoU)metrics using the mentioned dataset.

关键词： Computer aided diagnosis(CAd) magnetic resonance imaging(MRI) semantic segmentation lumbar vertebrae deep learning U-Net model

An SPH Framework for Earthquake-Induced Liquefaction Hazard Assessment of Geotechnical Structures

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 251-277页

作者： Sourabh Mhaski G.v.Ramana department of Civil Engineering Indian Institute of Technology DelhiNew Delhi110016India

Earthquake-induced soil liquefaction poses significant risks to the stability of geotechnical structures *** understanding of the liquefaction triggering,and the post-failure large deformation behaviour is essential for designing resilient *** present study develops a Smoothed Particle Hydrodynamics(SPH)framework for earthquake-induced liquefaction hazard assessment of geotechnical *** coupled flowdeformation behaviour of soils subjected to cyclic loading is described using the PM4Sand model implemented in a three-phase,single-layer SPH framework.A staggered discretisation scheme based on the stress particle SPH approach is adopted to minimise numerical inaccuracies caused by zero-energy modes and tensile ***,non-reflecting boundary conditions for seismic analysis of semi-infinite soil domains using the SPH method are *** numerical framework is employed for the analysis of cyclic direct simple shear test,seismic analysis of a level ground site,and liquefaction-induced failure of the Lower San Fernando *** agreement for liquefaction triggering and post-failure behaviour demonstrates that the SPH framework can be utilised to assess the effect of seismic loading on field-scale geotechnical *** present study also serves as the basis for future advancements of the SPH method for applications related to earthquake geotechnical engineering.

关键词： Earthquake seismic liquefaction stress particle PM4Sand smoothed particle hydrodynamics(SPH)

Autism spectrum disorder:difficulties in diagnosis and microRNA biomarkers

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Neural Regeneration Research 2025年第10期20卷 2776-2786页

作者： Bridget Martinez Philip v.Peplow department of Pharmacology University of Nevada-RenoRenoNVUSA department of Medicine University of Nevada-RenoRenoNVUSA department of Anatomy University of OtagoDunedinNew Zealand

We performed a PubMed search for microRNAs in autism spectrum disorder that could serve as diagnostic biomarkers in patients and selected 17 articles published from January 2008 to december 2023,of which 4 studies were performed with whole blood,4 with blood plasma,5 with blood serum,1 with serum neural cell adhesion molecule L1-captured extracellular vesicles,1 with blood cells,and 2 with peripheral blood mononuclear *** of the studies involved children and the study cohorts were largely *** of the studies had performed microRNA sequencing or quantitative polymerase chain reaction assays to measure microRNA *** five studies had used real-time polymerase chain reaction assay to validate microRNA expression in autism spectrum disorder subjects compared to *** microRNAs that were validated in these studies may be considered as potential candidate biomarkers for autism spectrum disorder and include miR-500a-5p,-197-5p,-424-5p,-664a-3p,-365a-3p,-619-5p,-664a-3p,-3135a,-328-3p,and-500a-5p in blood plasma and miR-151a-3p,-181b-5p,-320a,-328,-433,-489,-572,-663a,-101-3p,-106b-5p,-19b-3p,-195-5p,and-130a-3p in blood serum of children,and miR-15b-5p and-6126 in whole blood of *** important limitations were identified in the studies reviewed,and need to be taken into account in future *** studies are warranted with children and adults having different levels of autism spectrum disorder severity and consideration should be given to using animal models of autism spectrum disorder to investigate the effects of suppressing or overexpressing specific microRNAs as a novel therapy.

关键词： autism spectrum disorder biomarker blood cells blood plasma blood serum diagnosis microRNA peripheral blood mononuclear cells serum neural cell adhesion molecule L1-captured extracellular vesicles whole blood

MicroRNAs as potential diagnostic biomarkers for bipolar disorder

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Neural Regeneration Research 2025年第6期20卷 1681-1695页

Abnormal expression of microRNAs is connected to brain development and disease and could provide novel biomarkers for the diagnosis and prognosis of bipolar disorder. We performed a PubMed search for microRNA biomarkers in bipolar disorder and found 18 original research articles on studies performed with human patients and published from January 2011 to June 2023. These studies included microRNA profiling in bloodand brain-based materials. From the studies that had validated the preliminary findings,potential candidate biomarkers for bipolar disorder in adults could be miR-140-3p,-30d-5p,-330-5p,-378a-5p,-21-3p,-330-3p,-345-5p in whole blood, miR-19b-3p,-1180-3p,-125a-5p, let-7e-5p in blood plasma, and miR-7-5p,-23b-5p,-142-3p,-221-5p,-370-3p in the blood serum. Two of the studies had investigated the changes in microRNA expression of patients with bipolar disorder receiving treatment. One showed a significant increase in plasma miR-134 compared to baseline after 4 weeks of treatment which included typical antipsychotics, atypical antipsychotics, and benzodiazepines. The other study had assessed the effects of prescribed medications which included neurotransmitter receptorsite binders(drug class B) and sedatives, hypnotics, anticonvulsants, and analgesics(drug class C) on microRNA results. The combined effects of the two drug classes increased the significance of the results for miR-219 and-29c with miR-30e-3p and-526b* acquiring significance. MicroRNAs were tested to see if they could serve as biomarkers of bipolar disorder at different clinical states of mania, depression, and euthymia. One study showed that upregulation in whole blood of miR-9-5p,-29a-3p,-106a-5p,-106b-5p,-107,-125a-3p,-125b-5p and of miR-107,-125a-3p occurred in manic and euthymic patients compared to controls, respectively, and that upregulation of miR-106a-5p,-107 was found for manic compared to euthymic patients. In two other studies using blood plasma,downregulation of miR-134 was observed i

关键词： biomarker bipolar disorder blood leukocytes blood plasma blood plasma extracellular vesicles/exosomes blood serum brain tissue brain tissue extracellular vesicles/exosomes lymphoblastoid cell lines microRNA neural progenitor cells whole blood