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初次全膝关节置换术治疗老年胫骨平台骨折:文献回顾与我们的经验

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临床骨科杂志 2024年第1期27卷 132-132页

作者： SABATINI L APRATO A CAMAZZOLA d 胡孔足(摘译) 不详

老年人胫骨平台骨折的治疗非常具有挑战性,内固定术后继发创伤性关节炎,需要进行关节置换术比例非常高。2015~2019年,作者对11例外伤之前就合并骨关节炎的老年胫骨平台骨折患者进行全膝关节置换术,平均随访28个月。根据骨折类型和韧带情... 详细信息

老年人胫骨平台骨折的治疗非常具有挑战性,内固定术后继发创伤性关节炎,需要进行关节置换术比例非常高。2015~2019年,作者对11例外伤之前就合并骨关节炎的老年胫骨平台骨折患者进行全膝关节置换术,平均随访28个月。根据骨折类型和韧带情况,6例使用后稳定型假体,5例使用半限制性假体,末次随访KSS评分依次为(83±16)分和(74±15)分。未见假体松动。1例并发感染,1例并发假体周围骨折。

关键词：胫骨平台骨折创伤性关节炎关节置换术假体周围骨折骨关节炎末次随访内固定术后文献回顾

Uncovering current pyroregions in Italy using wildfire metrics

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Ecological Processes 2022年第1期11卷 259-275页

作者： Mario Elia Vincenzo Giannico davide Ascoli Juan Pablo Argañaraz Marina d’Este Giuseppina Spano Raffaele Lafortezza Giovanni Sanesi department of Agricultural and Environmental Sciences University of Bari A.MoroVia Amendola 165/A70126 BariItaly department of Agricultural Forest and Food SciencesUniversity of TurinLargo Braccini 210095 GrugliascoTOItaly Mario Gulich Institute for Advanced Space Studies(CONAE-UNC) CONICETRoute C45km 8CP 5187 Falda del CañeteCórdobaArgentina department of Geography The University of Hong KongCentennial CampusPokfulam RoadHong KongChina

Background:Pyrogeography is a major field of investigation in wildfire science because of its capacity to describe the spatial and temporal variations of fire *** propose a systematic pyrogeographic analytical approach to cluster regions on the basis of their *** employed the Affinity Propagation algorithm to cluster pyroregions using Italian landscape as a test bed and its current wildfire metrics in terms of density,seasonality and stand replacing fire ratio.A discussion follows on how pyrogeography varies according to differences in the human,biophysical,socioeconomic,and climatic ***:The algorithm identified seven different pyroregion *** main gradients were identified that partly explain the variability of wildfire metrics observed in the current ***,a gradient characterized by increasing temperatures and exposure to droughts,which coincides with a decreasing latitude,and second,a human pressure gradient displaying increasing population density in areas at lower *** drivers exerted a major influence on wildfire density,burnt area over available fuels and stand replacing,which were associated to warmdry climate and high human *** study statistically highlighted the importance of a North–South gradient,which represents one of the most important drivers of wildfire regimes resulting from the variations in climatic conditions but showing collinearity with socioeconomic aspects as ***:Our fully replicable analytical approach can be applied at multiple scales and used for the entire European continent to uncover new and larger *** could create a basis for the European Commission to promote innovative and collaborative funding programs between regions that demonstrate pyrosimilarities.

关键词： Pyrogeography Affinity propagation Forest Mediterranean basin Clustering

COVId-19 outbreak and surgical practice: The rationale for suspending non-urgent surgeries and role of testing modalities

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World Journal of Gastrointestinal Surgery 2020年第6期12卷 259-268页

作者： Andrew d Grubic Shahin Ayazi Javad Zebarjadi Hamed Tahmasbi Khosro Ayazi Blair A Jobe Esophageal and Lung Institute Department of SurgeryAllegheny Health NetworkPittsburghPA 15224United States department of Surgery Imam Hossein HospitalShahid Beheshti University of Medical SciencesTehran ***Iran

One-hundred years after the 1918-19 H1N1 flu pandemic and 10 years after the 2009 H1N1 flu pandemic, another respiratory virus has now inserted itself into the human population. Severe acute respiratory syndrome coronavirus has become a critical challenge to global health with immense economic and social disruption. In this article we review salient aspects of the coronavirus disease2019(COVId-19) outbreak that are relevant to surgical practice. The emphasis is on considerations during the pre-operative and post-operative periods as well as the utility and limitations of COVId-19 testing. The focus of the media during this pandemic is centered on predictive epidemiologic curves and models. While epidemiologists and infectious disease physicians are at the forefront in the fight against COVId-19, this pandemic is also a "stress test" to evaluate the capacity and resilience of our surgical community in dealing with the challenges imposed to our health system and society. As recently pointed out by dr. Anthony Fauci,the virus decides the timelines in the models. However, the models can also change based on our decisions and behavior. It is our role as surgeons, to make every effort to bend the curves against the virus’ will.

关键词： COVId-19 SARS-CoV-2 Surgery Pandemic Predictive model diagnosis

Studying ddTs in agricultural soils of selected rural communities of Armenia

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Acta Geochimica 2020年第4期39卷 487-496页

作者： G.Tepanosyan L.Sahakyan O.Belyaeva M.Beglaryan d.Pipoyan A.Hovhannisyan A.Saghatelyan The Center for Ecological-Noosphere Studies of the National Academy of Sciences RA Abovian-68 Street0025 YerevanRepublic of Armenia

To study organochlorine pesticides and organophosphorus pesticides contents and assess pesticideinduced health risk in Armenia,the contents of pesticides were determined in 252 soil samples taken from relatively large plots of agricultural land in 25 rural *** results showed that only∑ddT contents were detected in 39 out of 252 soil *** identified contents of∑ddT mainly consisted of pp’-ddE,suggesting historical use.6 out of 12 rural communities are characterized by the presence of former pesticide storehouses *** excesses versus Maximum Acceptable Concentration were observed in 26 out of 39 samples and ranges from 1.03 to 464.9 *** health risk assessment showed that non-carcinogenic risk is below the allowable level(HQddT is *** all studied rural communities,the presence of observed∑ddT and associated risk to the local population was detected mainly in the majority of sampling sites in Jrashen(Ararat region),Aramus(Kotayq region)and Khanjyan(Armavir region).Therefore,special attention should be given to the riskiest rural communities and risk reduction measures are needed to reduce or eliminate observed carcinogenic health effect.

关键词： Organochlorine pesticides ∑ddT Soil Pollution Health risk assessment

Hydrodynamic Instabilities in Rotating Fluids

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Journal of Thermal Science 2000年第2期9卷 103-108页

作者： Karl Buehler University of Applied Science (Fachhochschule) of Offenburg Badstrasse 24, d-77652 Offenburg, Germany University of Applied Science (Fachhochschule) of Offenburg Badstrasse 24 Offenburg Germany

Rotating flow systems are often used to study stability phenomena and structure developments. The closed spherical gap problem is generalized into an open now system by superimposing a mass flux in meridional direction. The basic solutions at low Reynolds numbers are described by analytical methods. The nonlinear supercritical solutions are simulated numerically and realized in experiments. Novel steady and time-dependent modes of flows are obtained. The extensive results concern the stability behaviour, non-uniqueness of supercritical solutions, symmetry behaviour and transitions between steady and time-dependent solutions. The experimental investigations concern the visualization of the various instabilities and the quatitative description of the flow structures including the laminar-turbulent transition. A comparison between theoretical and experimental results shows good agreement within the limit of rotational symmetric solutions from the theory.

关键词： Hydrodynamic instabilities rotating systems bifurcations structure development

Numerical　Simulation　of　the　Flow　over　a　Model　of　the　Cavities　on　a　Butterfly　Wing

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Journal of Thermal Science 1995年第3期4卷 185-192页

作者： Rodrigue Savoie Yves Gagnon (University de Moncton, Campus d’Edmundston, Edmundston (NB) Canada) Université de Moncton Campus d’Edmundston Edmundston Canada

The objective of this paper is to present results of numerical simulations for the flow over cavities modeling the scale structures on the upper surface of a typical butterfly wing. The numerical results,obtained using a vortex method, show that the dynamics of the flow are strongly dependent on the Reynolds number of the flow. The large coherent structures, formed in the cavity of adjoining scales, exhibit a stationary behaviour for low Reynolds number flows, while they exhibit strong dynamics and instabilities for high Reynolds number flows. The numerical results are in very good agreement with corresponding experimental results available in the literature.

关键词： vortex methods vorticity cavity butterfly.

Management of gastroesophageal reflux disease: Patient and physician communication challenges and shared decision making

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World Journal of Clinical Cases 2018年第15期6卷 892-900页

作者： Scott Klenzak Igor danelisen Grace d Brannan Melissa A Holland Miranda AL van Tilburg department of Psychiatry Cape Fear Valley Health System School of Osteopathic Medicine Campbell University College of Pharmacy and Health Sciences Campbell University division of Gastroenterology and Hepatology School of Medicine University of North Carolina University of Washington

Gastroesophageal reflux disease(GERd) is a common upper esophageal condition and typical symptoms can include heartburn and sensation of regurgitation while atypical symptoms include chronic cough, asthma, hoarseness, dyspepsia and nausea. Typically, diag-nosis is presumptive given the presence of typical and atypical symptoms and is an indication for empiric therapy. Treatment management can include lifestyle modifications and/or medication therapy with proton pump inhibitor(PPI) class being the preferred and most effective. Complete symptom resolution is not always achieved and long-term PPI therapy can put patients at risk for serious side effects and needless expense. The brain-gut connection and hypervigilance plays an important role in symptom resolution and treatment success, especially in the case of non-PPI responders. Hypervigilance is a combination of increased esophageal sensory sensitivity in combination with exaggerated threat perception surrounding esophageal symptoms. Hypervigilance requires a different approach to GERd managements, where continued PPI therapy and surgery are usually not recommended. Rather, helping physicians and patients understand the brain-gut connection can guide and improve *** and reassurance should be the main pillars or treatment. However, it is important not to suggest the symptoms are due to anxiety alone, this often leads to patient dissatisfaction. Patient dissatisfaction with treatment reveals the need for a more patient-centered approach to GERd management and better communication between patients and providers. Shared decision making(SdM) with the incorporation of patient-reported outcomes(PRO) promotes patient adherence and satisfaction. SdM is a joint discussion between clinician and patient in which a mutually shared solution is explored for GERd symptoms. For SdM to work the physician needs to capture patients' perceptions which may not be obtained in the standard interview. This can be done through the

关键词： Gastroesophageal reflux disease Psychosocial Patient-physician communication Shared decision making Patient-reported outcomes Patient satisfaction

Evaluation of atherosclerotic lesions in cholesterol-fed mice during treatment with paclitaxel in lipid nanoparticles： a magnetic resonance imaging study

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The Journal of Biomedical Research 2017年第2期31卷 116-121页

作者： Aline d. Lima Ning Hua Raul C. Maranhao James A. Hamilton Laboratory of Metabolism and Lipids Heart Institute of the Medical School HospitalSao PauloBrazil department of Physiology and Biophysics Boston University School of MedicineBostonMA 02118USA

Cholesterol-core nanoparticles （LdE） have been shown to be recognized by low-density lipoprotein receptors （LdLR） after administration; therefore, LdE is an ideal vehicle to deliver drug with targeting property. Paclitaxel, when incorporated into LdE, promotes atherosclerosis regression with reduced drug toxicity in rabbits through LdLR. Here, we tested whether LdE-paclitaxel could still be effective in reducing diet-induced atherosclerosis in a mouse model without LdLR. Nineteen LdLR knockout male mice were fed 1% cholesterol for 12 weeks. Then, 12 animals received 4-weekly intraperitoneal LdE-paclitaxel （4 mg/kg） while 7 controls received saline solution. On week 12 and 16, in vivo MR/of the aortic roots was performed. Aorta macroscopy was made after euthanasia. Reduction ofatherosclerotic lesions was observed. LdE-paclitaxel treatment resulted in reduction of wall area （14%） and stenosis （22%） by MR/and 33% by macroscopy. Thus, LdE-paclitaxel may produce pharmacological effects through LdE uptake by mechanisms other than LdLR.

关键词： atherosclerosis treatment lipid solid nanoparticles emulsions paclitaxel MRI drug targeting

detailed modeling of aluminum particle combustion——From single particles to cloud combustion in Bunsen flames

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Chinese Journal of Aeronautics 2022年第5期35卷 319-332页

作者： Jiarui ZHANG Oliver T.STEIN Tien d.LUU Ali SHAMOONI Zhixun XIA Zhenbing LUO Likun MA Yunchao FENG Andreas KRONENBURG College of Aerospace Science and Engineering National University of Defense TechnologyChangsha 410073China Institut für Technische Verbrennung Universitat StuttgartStuttgart 70174Germany

A numerical model for aluminum cloud combustion which includes the effects of interphase heat transfer,phase change,heterogeneous surface reactions,homogeneous combustion,oxide cap growth and radiation within the Euler–Lagrange framework is *** model is validated in single particle configurations with varying particle *** combustion process of a single aluminum particle is analyzed in detail and the particle consumption rates as well as the heat release rates due to the various physical/chemical sub-models are *** combustion time of single aluminum particles predicted by the model are in very good agreement with empirical correlations for particles with diameters larger than 10μ*** prediction error for smaller particles is noticeably reduced when using a heat transfer model that is capable of capturing the transition regime between continuum mechanics and molecular *** predictive capabilities of the proposed model framework are further evaluated by simulating the aluminum/air Bunsen flames of Mc Gill University for the first *** show that the predicted temperature distribution of the flame is consistent with the experimental data and the double-front structure of the Bunsen flame is reproduced *** burning rates of aluminum in both single particle and particle cloud configurations are calculated and compared with empirical *** show that the burning rates obtained from the present model are more reasonable,while the correlations,when embedded in the Euler–Lagrange context,tend to underestimate the burning rate in the combustion stage,particularly for the considered fuel-rich flames.

关键词： Aluminum particle combustion Bunsen flame Burning time Burning rate Particle cloud