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Optimal deep Learning Enabled Statistical Analysis Model for Traffic Prediction

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Computers, Materials & Continua 2022年第9期72卷 5563-5576页

作者： Ashit kumar dutta S.Srinivasan S.N.kumar T.S.Balaji Won il Lee Gyanendra Prasad Joshi Sung Won Kim department of Computer Science and Information Systems College of Applied SciencesAlMaarefa UniversityAd DiriyahRiyadh13713Kingdom of Saudi Arabia Institute of Biomedical Engineering Saveetha School of EngineeringSaveetha Institute of Medical and Technical SciencesSaveetha UniversitySaveetha NagarThandalamChennai602105India department of Electrical&Electronics Engineering Amal Jyothi College of EngineeringKanjirappallyKerala686518India Saveetha School of Engineering Saveetha Institute of Medical and Technical SciencesSaveetha UniversitySaveetha NagarThandalamChennai602105India department of Electronics and Communication Engineering College of Engineering and TechnologySRM Institute of Science and TechnologyVadapalani CampusChennai600026India department of Business Administration Hanbat National National UniversityDaejeon34158Korea department of Computer Science and Engineering Sejong UniversitySeoul05006Korea department of Information and Communication Engineering Yeungnam UniversityGyeongsan-siGyeongbuk-do38541Korea

due to the advances of intelligent transportation system(ITSs),traffic forecasting has gained significant interest as robust traffic prediction acts as an important part in different ITSs namely traffic signal control,navigation,route mapping,*** traffic prediction model aims to predict the traffic conditions based on the past traffic *** more accurate traffic prediction,this study proposes an optimal deep learning-enabled statistical analysis *** study offers the design of optimal convolutional neural network with attention long short term memory(OCNN-ALSTM)model for traffic *** proposed OCNN-ALSTM technique primarily preprocesses the traffic data by the use of min-max normalization ***,OCNN-ALSTM technique was executed for classifying and predicting the traffic data in real time *** enhancing the predictive outcomes of the OCNN-ALSTM technique,the bird swarm algorithm(BSA)is employed to it and thereby overall efficacy of the network gets *** design of BSA for optimal hyperparameter tuning of the CNN-ALSTM model shows the novelty of the *** experimental validation of the OCNNALSTM technique is performed using benchmark datasets and the results are examined under several *** simulation results reported the enhanced outcomes of the OCNN-ALSTM model over the recent methods under several dimensions.

关键词： Statistical analysis predictive models deep learning traffic prediction bird swarm algorithm

Remimazolam for sedation in gastrointestinal endoscopy:A comprehensive review

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World Journal of Gastrointestinal Endoscopy 2024年第7期16卷 385-395页

作者： dushyant Singh dahiya Ganesh kumar Syeda Parsa Manesh kumar Gangwani Hassam Ali Amir Humza Sohail Saqr Alsakarneh Umar Hayat Sheza Malik Yash R Shah Bhanu Siva Mohan Pinnam Sahib Singh Islam Mohamed Adishwar Rao Saurabh Chandan Mohammad Al-Haddad division of Gastroenterology Hepatology&MotilityThe University of Kansas School of MedicineKansas CityMO 66160United States department of Internal Medicine Chandka Medical CollegeSindh 77280Pakistan department of Gastroenterology and Hepatology University of Arkansas For Medical SciencesLittle RockAR 72205United States division of Gastroenterology Hepatology and NutritionEast Carolina University/Brody School of MedicineGreenvilleNC 27858United States department of Surgery University of New Mexico School of MedicineAlbuquerqueNM 87106United States department of Internal Medicine University of Missouri-Kansas CityKansas CityMO 64108United States department of Internal Medicine Geisinger Wyoming Valley Medical CenterWilkes BarrePA 18711United States department of Internal Medicine Rochester General HospitalRochesterNY 14621United States department of Internal Medicine Trinity Health Oakland/Wayne State UniversityPontiacMI 48341United States department of Internal Medicine John H.Stroger Hospital of Cook CountyChicagoIL 60612United States department of Internal Medicine Sinai hospitalBaltimoreMD 21215United States department of Hepatology University of MissouriColumbiaMO 65211United States department of Internal Medicine Guthrie Robert Packer HospitalSayrePA 18840United States division of Gastroenterology and Hepatology Creighton University School of MedicineOmahaNE 68131United States division of Gastroenterology and Hepatology Indiana University School of MedicineIndianapolisIN 46202United States

Worldwide,a majority of routine endoscopic procedures are performed under some form of sedation to maximize patient ***,benzodiazepines and opioids continue to be widely ***,in recent years,Remimazolam is gaining immense popularity for procedural sedation in gastrointestinal(GI)*** is an ultra-short-acting benzodiazepine sedative which was approved by the Food and drug Administration in July 2020 for use in procedural *** has shown a favorable pharmacokinetic and pharmacodynamic profile in terms of its non-specific metabolism by tissue esterase,volume of distribution,total body clearance,and negligible drug-drug *** also has satisfactory efficacy and has achieved high rates of successful sedation in GI ***,studies have demonstrated that the efficacy of Remimazolam is non-inferior to Propofol,which is currently a gold standard for procedural sedation in most parts of the ***,the use of Propofol is associated with hemodynamic instability and respiratory *** contrast,Remimazolam has lower incidence of these adverse effects intra-procedurally and hence,may provide a safer alternative to Propofol in procedural *** this comprehensive narrative review,highlight the pharmacologic characteristics,efficacy,and safety of Remimazolam for procedural *** also discuss the potential of Remimazolam as a suitable alternative and how it can shape the future of procedural sedation in gastroenterology.

关键词： Remimazolam Endoscopy Sedation Outcomes Efficacy Safety Pharmacokinetics

Role of fecal microbiota transplant in management of hepatic encephalopathy: Current trends and future directions

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World Journal of Hepatology 2024年第1期16卷 17-32页

作者： Yash R Shah Hassam Ali Angad Tiwari david Guevara-Lazo Natalia Nombera-Aznaran Bhanu Siva Mohan Pinnam Manesh kumar Gangwani Harishankar Gopakumar Amir H Sohail Srilakshmidevi Kanumilli Ernesto Calderon-Martinez Geetha Krishnamoorthy Nimish Thakral dushyant Singh dahiya department of Internal Medicine Trinity Health Oakland/Wayne State UniversityPontiacMI 48341United States division of Gastroenterology and Hepatology East Carolina University/Brody School of MedicineGreenvilleNC 27858United States department of Internal Medicine Maharani Laxmi Bai Medical CollegeJhansi 284001India Faculty of Medicine Universidad Peruana Cayetano HerediaLima 15102Peru department of Internal Medicine John H.Stroger Hospital of Cook CountyChicagoIL 60612United States department of Internal Medicine The University of ToledoToledoOH 43606United States department of Gastroenterology and Hepatology University of Illinois College of Medicine at PeoriaPeoriaIL 61605United States department of Surgery University of New MexicoAlbuquerqueNM 87106United States department of Internal Medicine GSL Medical CollegeRajamahendravaram 533296India department of Internal Medicine Universidad Nacional Autonoma de MexicoCiudad De Mexico 04510Mexico department of digestive diseases and Nutrition University of KentuckyLexingtonKY 40536United States division of Gastroenterology Hepatology&MotilityThe University of Kansas School of MedicineKansas CityKS 66160United States

Fecal microbiota transplantation(FMT)offers a potential treatment avenue for hepatic encephalopathy(HE)by leveraging beneficial bacterial displacement to restore a balanced gut *** prevalence of HE varies with liver disease severity and *** pathogenesis involves ammonia toxicity,gut-brain communication disruption,and *** aims to restore gut microbiota balance,addressing these ***'s efficacy has been explored in various conditions,including *** suggest that FMT can modulate gut microbiota,reduce ammonia levels,and alleviate *** has shown promise in alcohol-associated,hepatitis B and C-associated,and non-alcoholic fatty liver *** include improved liver function,cognitive function,and the slowing of disease ***,larger,controlled studies are needed to validate its effectiveness in these *** have shown cognitive improvements through FMT,with potential benefits in cirrhotic ***,trials have demonstrated reduced serious adverse events and cognitive enhancements in FMT arms compared to the standard of *** evidence is promising,challenges remain:Limited patient numbers,varied dosages,administration routes,and donor *** large-scale,controlled trials are essential to establish standardized guidelines and ensure FMT's clinical applications and *** FMT holds potential for HE management,ongoing research is needed to address these challenges,optimize protocols,and expand its availability as a therapeutic option for diverse hepatic conditions.

关键词： Hepatic encephalopathy Fecal microbiota transplant Cognitive impairment Liver cirrhosis Chronic liver disease

Guest Editorial:Special issue on explainable AI empowered for indoor positioning and indoor navigation

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CAAI Transactions on Intelligence Technology 2023年第4期8卷 1101-1103页

作者： Ki‐il Kim Aswani kumar Cherukuri Xue Jun Li Tanveer Ahmad Muhammad Rafiq Shehzad Ashraf Chaudhry Chungnam National University DaejeonRepublic of Korea Vellore Institute of Technology VelloreIndia Auckland University of Technology AucklandNew Zealand Yeungnam University Gyeongsan‐siRepublic of Korea Abu dhabi University Zayed CityUAE

The convergence of Internet of Things(IoT),vehicularad hoc network(VANET),and mobile ad hoc network relies on sensor networks to gather data from nodes or *** networks involve nodes,gateways,and anchors,operating on limited battery power,mainly used in *** applications,like healthcare,smart cities,and transportation,often need position data and face challenges in delay *** is important in ITS and VANETs,influencing autonomous vehicles,collision warning systems,and road information dissemination.A robust localisation system,often combining GPS with techniques like dead Reckoning and Image/Video Localisation,is essential for accuracy and *** intelligence(AI)integration,particularly in machine learning,enhances indoor wireless localisation *** in wireless communication(WSN,IoT,and massive MIMO)transform dense environments into programmable entities,but pose challenges in aligning self‐learning AI with sensor tech for accuracy and budget *** seek original research on sensor localisation,fusion,protocols,and positioning algorithms,inviting contributions from industry and academia to address these evolving challenges.

关键词： anchor artificial intelligence GPS localisation mobile communication RSSI vehicle

Functional recovery and muscle atrophy in pre-clinical models of peripheral nerve transection and gap-grafting in mice:effects of 4-aminopyridine

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Neural Regeneration Research 2023年第2期18卷 439-444页

作者： Jung il Lee M A Hassan Talukder Zara Karuman Anagha A.Gurjar Prem kumar Govindappa Jagadeeshaprasad M.Guddadarangaiah Kristen M.Manto Grant d.Wandling John P.Hegarty david L.Waning John C.Elfar department of Orthopaedics and Rehabilitation Center for Orthopaedic Research and Translational ScienceThe Pennsylvania State University College of MedicineHersheyPAUSA department of Orthopaedic Surgery Korea University Guro HospitalSeoulSouth Korea department of Cellular and Molecular Physiology The Pennsylvania State University College of MedicineHersheyPAUSA

We recently demonstrated a repurposing beneficial effect of 4-aminopyridine(4-AP),a potassium channel blocker,on functional recove ry and muscle atrophy after sciatic nerve crush injury in ***,this effect of 4-AP is unknown in nerve transection,gap,and grafting *** evaluate and compare the functional recovery,nerve morphology,and muscle atrophy,we used a novel stepwise nerve transection with gluing(STG),as well as 7-mm irreparable nerve gap(G-7/0)and 7-mm isografting in 5-mm gap(G-5/7)models in the absence and presence of 4-AP *** surgery,sciatic functional index was determined wee kly to evaluate the direct in vivo global motor functional *** 12 weeks,nerves were processed for whole-mount immunofluorescence imaging,and tibialis anterior muscles were harvested for wet weight and quantitative histomorphological analyses for muscle fiber crosssectional area and minimal Feret's *** post-injury sciatic functional index values in STG and G-5/7 models were significantly greater than those in the G-7/0 model.4-AP did not affect the sciatic functional index recovery in any *** to STG,nerve imaging revealed more misdirected axons and distorted nerve architecture with *** muscle weight,cross-sectional area,and minimal Feret's diameter were significantly smaller in G-7/0 model compared with STG and G-5/7,4-AP treatment significantly increased right TA muscle mass,cross-sectional area,and minimal Feret's diameter in G-7/0 *** findings demonstrate that functional recovery and muscle atrophy after peripheral nerve injury are directly related to the intervening nerve gap,and 4-AP exerts diffe rential effects on functional recove ry and muscle atrophy.

关键词： 4-aminopyridine functional recovery muscle atrophy nerve gap nerve grafting nerve imaging nerve transection

Immunomodulating property of Ocimum sanctum by regulating the il-2 production and its mRNA expression using rat's splenocytes

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Asian Pacific Journal of Tropical Medicine 2010年第1期3卷 8-12页

作者： Anjana Goel dilip kumar Singh Sandeep kumar Ashok kumar Bhatia department of Microbiology & Immunology College of Veterinary Sciences & Animal HusbandryU.P.Pt Deen Dayal Upadhyay Pasu Chikitsa Vigyan Vishwavidyalaya evam Go Anusandhan Sansthan(DUVASU)Mathura281001U.P.India

Objective:To investigate the regulatory effect of aqueous extract of leaves of Ocimum sanctum on il-2 cytokine production in vivo and in vitro,and the effect of leaves extract on general blood picture including T& B ***:For in vivo studies albino Wistar rats were treated with aqueous crude leaves extract of Ocimum sanctum for 20 consecutive *** cells were harvested and assayed for il-2 production by using sandwich enzyme-linked immunosorbent assay(ELISA) and mRNA expression *** in vitro study aqueous Ocimum sanctum leaves extract= in different concentrations(25-500μ/mL) was added into culture plates containing ConA stimulated *** study the overall effect on blood picture,density gradient purified lymphocytes analysis and conventional methodology for total and differential leukocyte count and hemoglobin level were also ***:It indicated that the rats treated with Ocimum sanctum leaves extract had significantly enhanced(Pility of spleen cells to secrete *** in vitro also showed regulation of il-2 *** study exhibited leucocytosis and augmentation of T& B lymphocytes by 25%approximately.4-5%increase in Hemoglobin value was also ***:Aqueous Ocimum sanctum leaves extract may have stimulatory effect on T & B lymphocytes particularly on Th 1 subset of lymphocytes as shown by enhancement in il-2 production.

关键词： B lymphocytes il-2 Ocimum sanctum Splenocytes T lymphocytes

Soluble factors secreted by human Wharton’s jelly mesenchymal stromal/stem cells exhibit therapeutic radioprotection: A mechanistic study with integrating network biology

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World Journal of Stem Cells 2022年第5期14卷 347-361页

作者： dharmendra kumar Maurya Mayuri Bandekar Santosh kumar Sandur Radiation Biology and Health Sciences division Bhabha Atomic Research CentreMumbai 400085MaharashtraIndia Homi Bhabha National Institute AnushaktinagarMumbai 400094India University of Mumbai KalinaMumbai 400098India

BACKGROUNd Human Wharton’s jelly-derived mesenchymal stromal/stem cells(hWJ-MSCs)have gained considerable attention in their applications in cell-based therapy due to several advantages offered by ***,we reported that hWJ-MSCs and their conditioned medium have significant therapeutic radioprotective *** finding raised an obvious question to identify unique features of hWJ-MSCs over other sources of stem cells for a better understanding of its radioprotective *** To understand the radioprotective mechanism of soluble factors secreted by hWJMSCs and identification of their unique *** Propidium iodide staining,endogenous spleen colony-forming assay,and survival study were carried out for radioprotection ***-driven proliferation assay was performed for in vivo lymphocyte *** of RNAseq data was performed to find the unique genes of WJ-MSCs by comparing them with bone marrow mesenchymal stem cells,embryonic stem cells,and human *** enrichment analysis and protein-protein interaction network were used for pathway *** Co-culture of irradiated murine splenic lymphocytes with WJ-MSCs offered significant radioprotection to ***-MSC transplantation increased the homeostasis-driven proliferation of the *** of WJ-MSC conditioned medium with granulocyte-colony stimulating factor antibody abolished therapeutic *** analysis showed that WJ-MSCs share several common genes with bone marrow MSCs and embryonic stem cells and express high levels of unique genes such as interleukin(il)1-α,il1-β,il-6,CXCL3,CXCL5,CXCL8,CXCL2,CCL2,FLT-1,and *** was also observed that WJ-MSCs preferentially modulate several cellular pathways and processes that handle the repair and regeneration of damaged tissues compared to stem cells from other ***-based network analysis showed that most of the radiosensitive tissues have a more com

关键词： Radioprotection Mesenchymal stem cells Wharton’s jelly-derived mesenchymal stromal/stem cells Cytokines Granulocyte-colony stimulating factor Network biology

Effect of Ocimum sanctum on the development of protective immunity against Salmonella typhimurium infection through cytokines

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Asian Pacific Journal of Tropical Medicine 2010年第9期3卷 682-686页

作者： Anjana Goel Sandeep kumar Ashok kumar Bhatia department of Microbiology & Immunology College of Veterinary Sciences & Animal HusbandryU.P.Pt Deen Dayal Upadhyay Pasu Chikitsa Vigyan Vishwavidyalaya evam Go Anusandhan Sansthan(DUVASU)Mathura281001U.P.India

Objective:To investigate the protective role of Ocimum sanctum（***） leaves against Salmonella ***（***） infection in rats by inducing TNF-α,IFN-γ& il-2 ***:Wistar albino rats were fed with aqueous extract of *** leaves using 250 mg/kg body weight dose once a day for 20 consecutive *** rats were fed with *** were infected with Ld50 dose of *** infection and monitored for their *** blood burden in both the groups was compared and numbers of activated peritoneal macrophages were *** of TNF-α,IFN-γand il-2 cytokines in serum during different time intervals was assayed by sandwich ***:Rats of control group showed a high mortality rate and had higher bacterial blood burden when compared with *** extract fed *** was a significant increase in the number of *** engulfed peritoneal macrophages in the peritoneal fluid of *** fed *** protective control against bacterial infection in O,sanctum fed rats was associated with elevated level of TNF-α,IFN-γand il-2 cytokines in ***:These findings suggest that orally administered *** leaves extract effectively enhanced activation in macrophage and lymphocytes,depicted by the elevated serum concentration of TNF-α,IFN-γand il-2 cytokines,leading to induce a protective resistance against Salmonella typhimurium infection.

关键词： Ocimum sanctum Salmonella typhimurium TNF-α IFN-γ il-2

Better-Than-Worst-Case design: Progress and Opportunities

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Journal of Computer Science & Technology 2014年第4期29卷 656-663页

作者：丛京生 Henry duwe Rakesh kumar 李森 ACM IEEE Computer Science department University of California Los Angeles CA 90095-1596 U.S.A. Electrical and Computer Engineering department University of Illinois at Urbana-Champaign Urbana IL 61801 U.S.A.

Today, designers are forced to reduce performance and increase power requirements in order to reserve larger margins that are required due to the greater variability introduced by smaller feature sizes and manufacturing variations of modern IC designs. The better-than-worst-case design can both address the variability problem and achieve higher performance/energy efficiency than the worst-case design. This paper surveys the progress to date, provides a snapshot of the most representative methods in this field, and discusses the future research directions of the better-than-worst-case design.

关键词： better-than-worst-case error resilience variability