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Advancing healthcare through laboratory on a chip technology:Transforming microorganism identification and diagnostics

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World Journal of Clinical Cases 2025年第3期13卷 9-19页

作者： Carlos m Ardila department of Basic Sciences Biomedical Stomatology Research GroupUniversidad de Antioquia U de AMedellín 0057Colombia

In a recent case report in the World Journal of Clinical Cases,emphasized the crucial role of rapidly and accurately identifying pathogens to optimize patient treatment ***-on-a-chip(LOC)technology has emerged as a transformative tool in health care,offering rapid,sensitive,and specific identification of *** editorial provides a comprehensive overview of LOC technology,highlighting its principles,advantages,applications,challenges,and future *** studies from the field have demonstrated the practical benefits of LOC devices in clinical diagnostics,epidemiology,and food *** studies have underscored the superiority of LOC technology over traditional methods,showcasing improvements in speed,accuracy,and *** future integration of LOC with biosensors,artificial intelligence,and data analytics promises further innovation and *** call to action emphasizes the importance of continued research,investment,and adoption to realize the full potential of LOC technology in improving healthcare outcomes worldwide.

关键词： Laboratory-on-a-chip microorganism identification diagnostics Point-ofcare testing Biosensors

motion of a spherical particle in a fluid forced vortex by dQm and dTm

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Particuology 2014年第5期12卷 206-212页

作者： m.Hatami d.d.Ganji Esfarayen University Department of Mechanical EngineeringEsfarayenNorth KhorasanIran mechanical Engineering Faculty Babol University of TechnologyBabolP.O.Box 484Iran

In this study, coupled equations of the motion of a particle in a fluid forced vortex were investigated using the differential transformation method （dTm） with the Pad6 approximation and the differential quadrature method （dO_m）. The significant contribution of the work is the introduction of two new, fast and efficient solutions for a spherical particle in a forced vortex that are improvements over the previous numerical results in the literature. These methods represent approximations with a high degree of accuracy and minimal computational effort for studying the particle motion in a fluid forced vortex. In addition, the velocity profiles （angular and radial） and the position trajectory of a particle in a fluid forced vortex are described in the current study.

关键词： Spherical particle Forced vortex differential transformation method (dTm)Angular velocity differential quadrature method (dQm)

Impact of Zika virus non-structural protein mutations on hippocampal damage

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Neural Regeneration Research 2025年第8期20卷 2307-2308页

作者： Larissa m.G.Cassiano Roney S.Coimbra Neurogenômica/Imunopatologia Instituto RenéRachouFiocruzBelo HorizonteBrazil departamento de Bioquímica e Imunologia Instituto de Ciências BiológicasUniversidade Federal de Minas GeraisBelo HorizonteBrazil

The Zika virus(ZIKV),a member of the Flaviviridae family,attracted worldwide attention for its connection to severe neurological effects,notably microcephaly in newborns,first reported during the 2015 epidemic in ***,its impact goes beyond fetal and neonatal abnormalities,also affecting the central nervous system(CNS)in both children and adults,leading to enduring cognitive and behavioral impairments.

关键词： damage fetal neonatal

Therapeutic approaches enhancing peripheral nerve regeneration

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Advances in Bioscience and Biotechnology 2013年第6期4卷 53-60页

作者： m. egle de Stefano Francesca Toni Valerio d’ Orazi Andrea Ortensi Ada maria Tata dip. di Biologia e Biotecnologie Charles darwin Sapienza Università di Roma Roma Italy Unità di microchirurgia Generale e Chirurgia della mano Casa di Cura Accreditata Fabia Mater Roma Italy

Peripheral nerve injury is a common occurrence and represents a major economic burden for society. The development of novel strategies to enhance peripheral nerve regeneration is, therefore, of great relevance. Conventional treatments include surgical repair of the damaged nerves for minor injuries, whereas autologous nerve grafts are required to recover longer interruptions. However, despite great surgical advances, functional recovery is often poor. Although it is well known that the peripheral nervous system has a greater regenerative capacity than the central nervous system and, considering the scientific advancements and knowledge in regenerative medicine, clinical applications appears still limited. This review provides an overview of the methodological approaches currently under study, aimed at enhancing peripheral nerve regeneration. In particular, tissue engineering, cell therapy and pharmacological approaches will be discussed.

关键词： Nerve Fibers Regeneration Schwann Cells Scaffolds Cell Therapy

Structure of Interphase Boundaries in Bimetallic Thin Films

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Journal of materials Science & Technology 2001年第1期17卷 59-60页

作者： m.d.Starostenkov G.m.Poletayev d.m.Starostenkov General Physics department Altai State Technical UniversityBarnaulRussia

The structural transformation in thin films of bimetals in the dependence on temperature and concentration of vacancies was investigated. The system Ni-Al structural transformation was realized by computer design according to the mechanism of self-sustained high(temperature synthesis. Structural transformation is characterized by the presence of dislocations, clusters of point defects and germs of intermetallic phases near interphase boundaries.

关键词： structural transformation intermetallic phases thin films

A comprehensive investigation on nonlinear vibration and bending characteristics of bio-inspired helicoidal laminated composite structures

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Applied mathematics and mechanics(English Edition) 2025年第1期46卷 81-100页

作者： S.SAURABH R.KIRAN d.SINGH R.VAISH V.S.CHAUHAN School of mechanical and materials Engineering Indian Institute of Technology Mandi

Bio-inspired helicoidal composite laminates, inspired by the intricate helical structures found in nature, present a promising frontier for enhancing the mechanical properties of structural designs. Hence, this study provides a comprehensive investigation into the nonlinear free vibration and nonlinear bending behavior of bio-inspired composite plates. The inverse hyperbolic shear deformation theory(IHSdT) of plates is employed to characterize the displacement field, with the incorporation of Green-Lagrange nonlinearity. The problem is modeled using the C0finite element method(FEm), and an in-house code is developed in the mATLAB environment to solve it numerically. Various helicoidal layup configurations including helicoidal recursive(HR), helicoidal exponential(HE), helicoidal semi-circular(HS), linear helicoidal(LH), and Fibonacci helicoidal(FH)with different layup sequences and quasi-isotropic configurations are studied. The model is validated, and parametric studies are conducted. These studies investigate the effects of layup configurations, side-to-thickness ratio, modulus ratios, boundary conditions, and loading conditions at different load amplitudes on the nonlinear vibration and nonlinear bending behaviors of bio-inspired composite plates. The results show that the laminate sequence exerts a substantial impact on both nonlinear natural frequencies and nonlinear bending behaviors. moreover, this influence varies across different side-to-thickness ratios and boundary conditions of the bio-inspired composite plate.

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dynamic modeling of a three-dimensional braided composite thin plate considering braiding directions

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Applied mathematics and mechanics(English Edition) 2025年第1期46卷 123-138页

作者： Chentong GAO Huiyu SUN Jianping GU W.m.HUANG College of Aerospace Engineering Nanjing University of Aeronautics and Astronautics School of mechanical and Aerospace Engineering Nanyang Technological University Jiangsu Key Laboratory of Advanced Structural materials and Application Technology School of Materials Science and EngineeringNanjing Institute of Technology

Currently, there are a limited number of dynamic models available for braided composite plates with large overall motions, despite the incorporation of three-dimensional(3d) braided composites into rotating blade components. In this paper, a dynamic model of 3d 4-directional braided composite thin plates considering braiding directions is established. Based on Kirchhoff's plate assumptions, the displacement variables of the plate are expressed. By incorporating the braiding directions into the constitutive equation of the braided composites, the dynamic model of the plate considering braiding directions is obtained. The effects of the speeds, braiding directions, and braided angles on the responses of the plate with fixed-axis rotation and translational motion, respectively, are investigated. This paper presents a dynamic theory for calculating the deformation of 3d braided composite structures undergoing both translational and rotational motions. It also provides a simulation method for investigating the dynamic behavior of non-isotropic material plates in various applications.

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The electrical impedance, AC conductivity and dielectric properties of phenol red compound investigated and modeled by an artificial neural network

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Communications in Theoretical Physics 2020年第10期72卷 139-148页

作者： H A m Ali d m Habashy Physics department Faculty of EducationAin Shams UniversityRoxyCairo 11757Egypt

The impedance spectroscopy,electrical conductivity and electric modulus of bulk phenol red were measured,as a function of both frequency and *** neural networks(ANNs)were used for modeling its electrical *** two parts(real and imaginary)of its complex impedance(Z^*)were analyzed and the activation energy related to the electrical relaxation process was *** curves were plotted showing semicircles for the different *** AC electrical conductivity follows a power lawσac(ω)αω^η.The maximum barrier height Bm was derived for specific temperatures.A plausible mechanism for the AC conduction of bulk phenol red was deduced from the temperature reliance of the frequency *** dielectric data was analyzed using electric modulus as a *** addition,ANNs were used to model the impedance parts and the total electrical *** runs were tried,to obtain the best *** training and prediction results were compared to the equivalent experimental results,with a good match *** equation describing the experimental results was obtained mathematically,based on the use of *** outputs demonstrated that ANNs are an admirable tool for modeling experimental results.

关键词： phenol red impedance spectroscopy electric modulus neural network

An Iterative Relaxation Approach to the Solution of the Hamilton-Jacobi-Bellman-Isaacs Equation in Nonlinear Optimal Control

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IEEE/CAA Journal of Automatica Sinica 2018年第1期5卷 360-366页

作者： m.d.S.Aliyu department of Electrical Engineering King Faisal University Al-Ahsa 31982 Saudi Arabia IEEE

In this paper, we propose an iterative relaxation method for solving the Hamilton-Jacobi-Bellman-Isaacs equation(HJBIE) arising in deterministic optimal control of affine nonlinear systems. Local convergence of the method is established under fairly mild assumptions, and examples are solved to demonstrate the effectiveness of the method. An extension of the approach to Lyapunov equations is also discussed. The preliminary results presented are promising, and it is hoped that the approach will ultimately develop into an efficient computational tool for solving the HJBIEs.

关键词： Affine nonlinear system bounded continuous function convergence Hamilton-Jacobi-Bellman-Isaacs equation Lyapunov equation relaxation method Riccati equation