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World Journal of Gastroenterology 2011年第5期17卷 677-680页

作者： Giovanni d de Palma Stefania Staibano Saverio Siciliano Francesco Maione Maria Siano dario Esposito Giovanni Persico department of Surgery and Advanced Technologies Center of Excellence for Technical Innovation in SurgerySection of Diagnostic and Therapeutic EndoscopyUniversity of Naples Federico IISchool of Medicine80131NaplesItaly department of Biomorphological and Functional Sciences Section of PathologyUniversity of Naples Federico IISchool of Medicine80131NaplesItaly

Recently,the use of confocal laser endomicroscopy(CLE) in the diagnosis of chronic ulcerative colitis(CUC) was *** this brief report we aimed to assess the application of probe-based CLE to characterize colonic mucosa and dysplasia in *** study involved a patient presenting long-standing *** imaging of both the inflamed mucosa,a circumscribed lesion(dysplasiaassociated lesional mass),and adjacent colonic mucosa are demonstrated and the correlation between the CLE and histological *** mucosa and dysplasia showed specific alteration of crypt architecture,cellular infiltration,and vessel architecture with an excellent correlation between CLE and standard histological examination.

关键词： Colonoscopy Confocal laser endomicros-copy Chronic ulcerative colitis dysplasia-associatedlesional mass Histology

Laser speckle contrast imaging for monitoring of acutepancreatitis at ischemia-reperfusion injury of thepancreas in rats

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Journal of Innovative Optical Health Sciences 2022年第1期15卷 90-102页

作者： P.A.dyachenko(Timoshina) A.N.Bashkatov d.A.Alexandrov V.I.Kochubey V.V.Tuchin Saratov State University SaratovRussia Laboratories of Biophotonics and Laser Molecular Imaging and Machine Learning National Research Tomsk State University TomskRussia Saratov State Medical University SaratovRussia Institute of Precision Mechanics and Control Russian Academy of SciencesRussia A.N.Bach Institute of Biochemistry Research Center of Biotechnology of the Russian Academy of Sciences MoscowRussia

The influence of ischemia-reperfusion(I/R)action on pancreatic blood flow(PBF)and the development of acute pancreatitis(AP)in laboratory rats is evaluated in vivo by using the laser speckle contrast imaging(LSCI).Additionally,the optical properties in norm and under condition of AP in rats were assessed using a modied integrating sphere spectrometer and inverse Monte Carlo(IMC)*** results of the experimental study of microcirculation of the pancreas in 82 rats in the ischemic model are *** data obtained conrm the fact that local ischemia and changes in the blood°ow velocity of the main vessels cause and provoke acute pancreatitis.

关键词： Laser speckles contrast of speckle images adaptive algorithm microcirculation blood flow acute pancreatitis pancreas rats optical properties integrating sphere spectroscopy

Supranutrition of microalgal docosahexaenoic acid and calcidiol improved growth performance,tissue lipid profiles,and tibia characteristics of broiler chickens

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Journal of Animal Science and Biotechnology 2023年第4期14卷 1542-1550页

作者： Sahil Kalia Andrew d.Magnuson Tao Sun Guanchen Liu Woo Kyun Kim Zackary Johnson Xin Gen Lei department of Animal Science Cornell University252 Morrison HallIthacaNY 14850USA department of Poultry Science University of GeorgiaAthensGAUSA Nicholas School of the Environment Duke UniversityBeaufortNCUSA

Background docosahexaenoic acid(dHA)and calcidiol could be enriched in chicken for improving public nutrition and *** remains unclear if supranutritional levels of dHA and calcidiol impair growth performance or metabolism of broiler *** study was to determine singular and combined effects of high levels of supplemental dHA-rich microalgal biomass or oil and calcidiol on growth performance,concentrations of triglycerides,cholesterol,and nonesterfied fatty acids in plasma,liver,breast,and thigh,and biophysical properties of *** In Exp.1,144 day-old Cornish chicks were divided into 4 groups(6 cages/treatment,6 birds/cage),and were fed a corn-soybean meal basal diet(Bd),Bd+10,000 IU calcidiol/kg(Bd+Cal),Bd HA),and Bd+1%dHA-rich Aurantiochytrium(1.2 g dHA/kg;Bd+d+Cal+dHA for 6 *** Exp.2,180 day-old chicks were divided into5 groups,and were fed:Bd,Bd+dHA(0.33%to 0.66%oil,1.5 to 3.0 g dHA/kg),Bd EPA/kg),Bd+dHA+EPA(1.9%to 3.8%eicosapentaenoic acid-rich Nannochloropsis ***18,0.3 to 0.6 g Bd+dHA+calcidiol(6000 to 12,000 IU/kg diet),and+dHA+EPA+Cal for 6 *** Birds fed Bd+Cal diet in Exp.1 and Bd lower(P+dHAdiet in Exp.2 had higher(Pdy weight gain(10%-11%)and gain:feed ratio(7%),and total cholesterol and triglyceride concentrations in plasma(18%-54%),liver(8%-26%),breast(19%-26%),and thigh(10%-19%),respectively,over the *** two diets also improved(Pd(or)bone mineral density(3%-19%)of *** Supranutrition of dietary calcidiol and dHA alone or together did not produce adverse effects,but led to moderate improvements of growth performance,lipid profiles of plasma and muscle,and bone properties of broiler chickens.

关键词： Broiler Calcidiol Growth performance Microalgae Tibia

dispase rapidly and effectively purifies Schwann cells from newborn mice and adult rats

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Neural Regeneration Research 2012年第4期7卷 256-260页

作者： Jiaxue Zhu Jinbao Qin Zunli Shen James d. Kretlow Xiaopan Wang Zhangyin Liu Yuqing Jin department of Plastic and Reconstructive Surgery Shanghai First People＇s Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200080 China Stem Cell and Tissue Engineering Research Center Shanghai First People＇s Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200080 China department of Bioengineering Rice University Houston 77251-1892 TX USA

In the present study, Schwann cells were isolated from the sciatic nerve of neonatal mice and purified using dispase and collagenase. Results showed that after the first round of purification with dispase, most of the Schwann cells appeared round in shape and floated in culture solution after 15 minutes. In addition, cell yield and cell purity were higher when compared to the collagenase group. After the second round of purification, the final cell yield for the dispase group was higher than that for the collagenase group, but no significant difference was found in cell purity. Moreover, similar results in cell quantity and purity were observed in adult Sprague-dawley rats. These findings indicate that purification with dispase can result in the rapid isolation of Schwann cells with a high yield and purity.

关键词： dispase differential detachment purification Schwann cell neural regeneration

daily expression of sodium-dependent glucose cotransporter-1protein in jejunum during rat ontogeny

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Animal Nutrition 2019年第3期5卷 290-296页

作者： Juan I.Baston Fabricio d.Cid Enrique Caviedes-Vidal Juan G.Chediack Laboratorio de Fisiopatología Endometrial Instituto de Biología y Medicina Experimental(IByME)CONICETCiudad Autoonoma de Buenos AiresC1428ADNArgentina Laboratorio de Biología Integrativa“Prof.E.Caviedes Codelia” Facultad de QuímicaBioquímica y FarmaciaUniversidad Nacional de San LuisSan LuisD5700HHWArgentina Instituto Multidisciplinario de Investigaciones en Biología-San Luis(IMIBIO-SL CCT-SL)CONICETSan Luis D5700HHWArgentina

It is widely known that intestinal capacities such as the enzymatic hydrolysis of carbohydrates,lipids and proteins,and the subsequent absorption of the hydrolyzed *** evolutionary matched to dietary loads and feeding *** this study,we demonstrate that the protein expression of apically located sodium-dependent glucose cotransporter-1(SGLT-1)throughout rat ontogeny is daily adjusted to afford glucose uptake when the load of this metabolically essential monosaccharide in the intestinal lumen is *** jejunal expression of SGLT-1 protein in 14 one-day-old suckling pups was found to increase at dark and early light phase(Pd-old and juvenile 28-d-old rats,the cotransporter expression was high throughout the entire day(Pdult 90-d-old rats showed a well-developed circadian rhythm for SGLT-1 protein(Pd at late light and dark phase when the highest intestinal glucose load was *** our knowledge,these results are the first reporting the daily profile of SGLT-1 expression during rat early developmental stage and may contribute to understand the biological significance of a well-established molecular capacity to deal with the crucial increase of glucose load in the diet during the weaning process.

关键词： Intestinal SGLT-1 Protein expression daily rhythms Ontogeny Rat

Assessing the impact of conceptual mineral systems uncertainty on prospectivity predictions

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Geoscience Frontiers 2022年第6期13卷 182-207页

作者： Mark d Lindsay Agnieszka M.Piechocka Mark W Jessell Richard Scalzo Jeremie Giraud Guillaume Pirot Edward Cripps Commonwealth Scientific and Industrial Research Organisation Mineral Resources Australian Resources Research CentreWA 6151Australia Mineral Exploration Cooperative Research Centre Centre for Exploration TargetingSchool of Earth SciencesThe University of Western AustraliaPerthWA 6009Australia ARC Centre for data Analytics for Resources and Environments(dARE) Perth and SydneyAustralia University of Sydney School of Mathematics and StatisticsSydneyAustralia Universitéde Lorraine GeoRessourcesCNRS54000 NancyFrance The University of Western Australia Department of Mathematics and StatisticsPerthAustralia

The past two decades have seen a rapid adoption of artificial intelligence methods applied to mineral exploration. More recently, the easier acquisition of some types of data has inspired a broad literature that has examined many machine learning and modelling techniques that combine exploration criteria,or ’features’, to generate predictions for mineral prospectivity. Central to the design of prospectivity models is a ’mineral system’, a conceptual model describing the key geological elements that control the timing and location of economic mineralisation. The mineral systems model defines what constitutes a training set, which features represent geological evidence of mineralisation, how features are engineered and what modelling methods are used. Mineral systems are knowledge-driven conceptual models, thus all parameter choices are subject to human biases and opinion so alternative models are ***, the effect of alternative mineral systems models on prospectivity is rarely compared despite the potential to heavily influence final predictions. In this study, we focus on the effect of conceptual uncertainty on Fe ore prospectivity models in the Hamersley region, Western Australia. Four important considerations are tested.(1) Five different supergene and hypogene conceptual mineral systems models guide the inputs for five forest-based classification prospectivity models model.(2) To represent conceptual uncertainty, the predictions are then combined for prospectivity model comparison.(3)Representation of three-dimensional objects as two-dimensional features are tested to address commonly ignored thickness of geological units.(4) The training dataset is composed of known economic mineralisation sites(deposits) as ’positive’ examples, and exploration drilling data providing ’negative’sampling locations. Each of the spatial predictions are assessed using independent performance metrics common to AI-based classification methods and subjected to geological pl

关键词： Uncertainty Modelling Prospectivity Economic geology Geological plausibility Forest-based classification

Geochemical and Nd-Sr Isotopic Compositions of Hypabyssal Adakites in the Torud-Ahmad Abad Magmatic Belt,Northern Central Iran Zone:Analysis of Petrogenesis and Geodynamic Implications

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Journal of Earth Science 2021年第6期32卷 1428-1444页

作者： Fazilat Yousefi Ryan d.Mills Mahmoud Sadeghian david R.Lentz Christina Wanhainen Habibollah Ghasemi Laicheng Miao department of Earth Sciences University of New BrunswickFrederictonCanada department of Geological Sciences University of North Carolina at Chapel HillChapel HillUSA Faculty of Earth Sciences Shahrood University of TechnologyShahroodIran department of Civil Environmental and Natural Resources EngineeringLulea University of TechnologyLuleaSweden Institute of Geology and Geophysics Chinese Academy of SciencesBeijing100029China

Eocene intermediate to felsic subvolcanic rocks of the Torud-Ahmad Abad magmatic belt(TAMB),in the northern part of the Central Iran zone,are exposed between the Torud and Ahmad Abad regions in South-Southeast *** igneous rocks include hypabyssal dacite,trachyte,andesite,trachy-andesite,and basaltic andesite;they are mainly composed of phenocrysts and microcrystalline groundmass of pyroxene,amphibole,and plagioclase,with minor biotite and titanomagnetite;they form domal structures(plugs and stocks),dikes,and sills that intruded into Neoproterozoic to cogenetic Eocene volcano-sedimentary *** on isotopic analysis of these intermediate to acidic rocks,initial ratios of^(143)Nd/^(144)Nd range from 0.512775 to 0.512893 and initial ratios of^(87)Sr/^(86)Sr range from 0.703746 to 0.705314,with quite positiveε_(Nd(i))values of+3.69 to+*** are enriched in light rare earth elements and large ion lithophile elements and depleted in heavy rare earth elements and high-field strength elements,the SiO_(2) content is(52-62)wt.%,and Na_(2)O content>3 wt.%,Al_(2)O_(3) content>16 wt.%,Ybd Yd Sr and Nd isotopic data are consistent with adakitic signatures originating by partial melting of the subducted Neo-Tethys oceanic slab(Sabzevar branch)and lithospheric suprasubduction zone *** mantle signatures typifying the rapidly emplaced adakitic rocks(slab(high-silica adakite)and suprasubduction zone(low-silica adakite)melts)together with their locally voluminous extent are evidences that support a locally extensional geodynamic setting;and the evidence is consistent with an evolution to local transpression in the Late Eocene in this convergent margin are environment to rifting(basalts to adakites)towards submarine conditions in the Neogene.

关键词： isotope geochemistry adakite rocks Central Iran zone Shahrood Iran

Bayes-Q-Learning Algorithm in Edge Computing for Waste Tracking

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Intelligent Automation & Soft Computing 2023年第5期36卷 2425-2440页

作者： d.Palanikkumar R.Ramesh Kumar Mehedi Masud Mrim M.Alnfiai Mohamed Abouhawwash department of Computer Science and Engineering Dr.NGP Institute of TechnologyCoimbatore641048India department of Information Technology Sri Krishna College of TechnologyCoimbatore641042India department of Computer Science College of Computers and Information TechnologyTaif UniversityP.O.Box 11099Taif21944Saudi Arabia department of Information Technology College of Computers and Information TechnologyTaif UniversityTaif P.O.Box 11099Taif21944Saudi Arabia department of Mathematics Faculty of ScienceMansoura UniversityMansoura35516Egypt department of Computational Mathematics Scienceand Engineering(CMSE)Michigan State UniversityEast LansingMI48824USA

The major environmental hazard in this pandemic is the unhygienic dis-posal of medical *** wastage is not properly managed it will become a hazard to the environment and *** medical wastage is a major issue in the city,municipalities in the aspects of the environment,and *** efﬁcient supply chain with edge computing technology is used in managing medical *** supply chain operations include processing of waste collec-tion,transportation,and disposal of *** research works have been applied to improve the management of *** main issues in the existing techniques are ineffective and expensive and centralized edge computing which leads to failure in providing security,trustworthiness,and *** over-come these issues,in this paper we implement an efﬁcient Naive Bayes classiﬁer algorithm and Q-Learning algorithm in decentralized edge computing technology with a binary bat optimization algorithm(NBQ-BBOA).This proposed work is used to track,detect,and manage medical *** minimize the transferring cost of medical wastage from various nodes,the Q-Learning algorithm is *** accuracy obtained for the Naïve Bayes algorithm is 88%,the Q-Learning algo-rithm is 82%and NBQ-BBOA is 98%.The error rate of Root Mean Square Error(RMSE)and Mean Error(MAE)for the proposed work NBQ-BBOA are 0.012 and 0.045.

关键词： Binary bat algorithm naïve bayes supply chain edge medical wastage

In-chamber thermocatalytic tar cracking and syngas reforming using char-supported NiO catalyst in an updraft biomass gasifier

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International Journal of Agricultural and Biological Engineering 2014年第6期7卷 91-97页

作者： Arthur M.James R Wenqiao Yuan Michael d.Boyette donghai Wang Ajay Kumar department of Biological and Agricultural Engineering North Carolina State UniversityRaleighNC 27695-7625USA department of Biological and Agricultural Engineering Kansas State UniversityManhattanKS 66506-2906USA department of Biosystems and Agricultural Engineering Oklahoma State UniversityStillwaterOK74078-6016USA

The objective of this study was to evaluate the performance of an in-chamber tar cracking and syngas reforming *** unit was composed of a two-stage tubular reactor placed within the combustion zone of an updraft biomass *** generated in the exothermic combustion reactions of biomass gasification drove tar cracking and syngas reforming in the tubes,eliminating the need of external *** performance of the unit was evaluated using char-supported NiO catalysts and was found to be very effective in tar removal and syngas composition enhancement.A tar removal rate of 95% was achieved at 0.3 s residence time and 10%nickel *** condition also gave syngas high-heating value increment of 36%(to 7.3 MJ/m^(3)).The effect of gas residence time and Ni loading on tar removal and syngas composition of the unit was also *** residence of 0.2-0.3 s and Ni loading of 5%-10% were found appropriate to produce clean syngas with tar content appropriate for industrial applications(draft biomass gasifier without external heating.

关键词： biomass gasification tar cracking syngas reforming nickel catalyst char catalyst

Controlling flowering of Medicago sativa(alfalfa)by inducing dominant mutations

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Journal of Integrative Plant Biology 2022年第2期64卷 205-214页

作者： Maurizio Junior Chiurazzi Anton Frisgaard Nørrevang Pedro García Pablo d.Cerdán Michael Palmgren Stephan Wenkel NovoCrops Center University of CopenhagenThorvaldsensvej 40Frederiksberg C1871 Denmark Copenhagen Plant Science Centre University of CopenhagenThorvaldsensvej 40Frederiksberg C1871 Denmark department of Plant and Environmental Sciences University of CopenhagenThorvaldsensvej 40Frederiksberg C1871 Denmark Fundación Instituto Leloir IIBBA-CONICETAvenida Patricias Argentinas 435Buenos Aires1405 Argentina

Breeding plants with polyploid genomes is challenging because functional redundancy hampers the identification of loss-of-function *** sativa is tetraploid and obligate outcrossing,which together with inbreeding depression complicates traditional breeding approaches in obtaining plants with a stable growth *** dominant mutations would provide an alternative strategy to introduce domestication traits in plants with high gene *** we describe two complementary strategies to induce dominant mutations in the *** genome and how they can be relevant in the control of flowering ***,we outline a genome-engineering strategy that harnesses the use of microProteins as developmental *** are small proteins that appeared during genome evolution from genes encoding larger *** allows us to retrace evolution and create microProtein-coding genes de ***,we provide an inventory of genes regulated by microRNAs that control plant *** respective gene transcripts microRNA-resistant by inducing point mutations can uncouple microRNA ***,we investigated the recently published genomes of *** and provide an inventory of breeding targets,some of which,when mutated,are likely to result in dominant traits.

关键词： flowering time genome-engineering Medicago sativa microProtein microRNA