检索结果-南通市图书馆

Evidence for particle acceleration approaching PeV energies in the W51 complex

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science Bulletin 2024年第18期69卷 2833-2841页

作者： Cao, Zhen Aharonian, F. Axikegu Bai, Y.X. Bao, Y.W. Bastieri, d. Bi, X.J. Bi, Y.J. Bian, W. Bukevich, A.V. Cao, q. Cao, W.Y. Cao, Zhe Chang, J. Chang, J.F. Chen, A.M. Chen, E.S. Chen, h.X. Chen, liang Chen, lin Chen, long Chen, M.J. Chen, M.l. Chen, q.h. Chen, S. Chen, S.h. Chen, S.Z. Chen, T.l. Chen, Y. Cheng, N. Cheng, Y.d. Cui, M.Y. Cui, S.W. Cui, X.h. Cui, Y.d. dai, B.Z. dai, h.l. dai, Z.G. danzengluobu dong, X.q. duan, K.K. Fan, J.h. Fan, Y.Z. Fang, J. Fang, J.h. Fang, K. Feng, C.F. Feng, h. Feng, l. Feng, S.h. Feng, X.T. Feng, Y. Feng, Y.l. Gabici, S. Gao, B. Gao, C.d. Gao, q. Gao, W. Gao, W.K. Ge, M.M. Geng, l.S. Giacinti, G. Gong, G.h. Gou, q.B. Gu, M.h. Guo, F.l. Guo, X.l. Guo, Y.q. Guo, Y.Y. han, Y.A. hasan, M. he, h.h. he, h.N. he, J.Y. he, Y. hor, Y.K. hou, B.W. hou, C. hou, X. hu, h.B. hu, q. hu, S.C. huang, d.h. huang, T.q. huang, W.J. huang, X.T. huang, X.Y. huang, Y. Ji, X.l. Jia, h.Y. Jia, K. Jiang, K. Jiang, X.W. Jiang, Z.J. Jin, M. Kang, M.M. Karpikov, I. Kuleshov, d. Kurinov, K. li, B.B. li, C.M. li, Cheng li, Cong li, d. li, F. li, h.B. li, h.C. li, Jian li, Jie li, K. li, S.d. li, W.l. li, X.R. li, Xin li, Y.Z. li, Zhe li, Zhuo liang, E.W. liang, Y.F. lin, S.J. liu, B. liu, C. liu, d. liu, d.B. liu, h. liu, h.d. liu, J. liu, J.l. liu, M.Y. liu, R.Y. liu, S.M. liu, W. liu, Y. liu, Y.N. luo, q. luo, Y. lv, h.K. Ma, B.q. Ma, l.l. Ma, X.h. Mao, J.R. Min, Z. Mitthumsiri, W. Mu, h.J. Nan, Y.C. Neronov, A. Ou, l.J. Pattarakijwanich, P. Pei, Z.Y. qi, J.C. qi, M.Y. qiao, B.q. qin, J.J. Raza, A. Ruffolo, d. Sáiz, A. Saeed, M. Semikoz, d. Shao, l. Shchegolev, O. Sheng, X.d. Shu, F.W. Song, h.C. Stenkin, Yu.V. Stepanov, V. Su, Y. Sun, d.X. Sun, q.N. Sun, X.N. Sun, Z.B. Takata, J. Tam, P.h.T. Key laboratory of Particle Astrophysics & Experimental Physics division & Computing Center Institute of High Energy Physics Chinese Academy of Sciences Beijing 100049 China University of Chinese Academy of Sciences Beijing 100049 China TIANFU Cosmic Ray Research Center Chengdu China dublin Institute for Advanced Studies 31 Fitzwilliam Place 2 Dublin Ireland Max-Planck-Institut for Nuclear Physics P.O. Box 103980 Heidelberg 69029 Germany School of Physical Science and Technology & School of Information Science and Technology Southwest Jiaotong University Chengdu 610031 China School of Astronomy and Space Science Nanjing University Nanjing 210023 China Center for Astrophysics Guangzhou University Guangzhou 510006 China Tsung-dao lee Institute & School of Physics and Astronomy Shanghai Jiao Tong University Shanghai 200240 China Institute for Nuclear Research of Russian Academy of Sciences Moscow 117312 Russia hebei Normal University Shijiazhuang 050024 China University of Science and Technology of China Hefei 230026 China State Key laboratory of Particle detection and Electronics China Key laboratory of dark Matter and Space Astronomy & Key laboratory of Radio Astronomy Purple Mountain Observatory Chinese Academy of Sciences Nanjing 210023 China Research Center for Astronomical Computing Zhejiang Laboratory Hangzhou 311121 China Key laboratory for Research in Galaxies and Cosmology Shanghai Astronomical Observatory Chinese Academy of Sciences Shanghai 200030 China School of Physics and Astronomy Yunnan University Kunming 650091 China Key laboratory of Cosmic Rays (Tibet University) Ministry of Education Lhasa 850000 China National Astronomical Observatories Chinese Academy of Sciences Beijing 100101 China School of Physics and Astronomy (Zhuhai) & School of Physics (Guangzhou) & Sino-French Institute of Nuclear Engineering and Technology (Zhuhai) Sun Yat-sen University Zhuhai 519000 & Guangzhou 510275 Guangdong China Institute of Frontier and

The γ-ray emission from the W51 complex is widely acknowledged to be attributed to the interaction between the cosmic rays (CRs) accelerated by the shock of supernova remnant (SNR) W51C and the dense molecular clouds in the adjacent star-forming region, W51B. however, the maximum acceleration capability of W51C for CRs remains elusive. Based on observations conducted with the large high Altitude Air Shower Observatory (lhAASO), we report a significant detection of γ rays emanating from the W51 complex, with energies from 2 to 200 TeV. The lhAASO measurements, for the first time, extend the γ-ray emission from the W51 complex beyond 100 TeV and reveal a significant spectrum bending at tens of TeV. By combining the "π0-decay bump" featured data from Fermi-lAT, the broadband γ-ray spectrum of the W51 region can be well-characterized by a simple pp-collision model. The observed spectral bending feature suggests an exponential cutoff at ∼400 TeV or a power-law break at ∼200 TeV in the CR proton spectrum, most likely providing the first evidence of SNRs serving as CR accelerators approaching the PeV regime. Additionally, two young star clusters within W51B could also be theoretically viable to produce the most energetic γ rays observed by lhAASO. Our findings strongly support the presence of extreme CR accelerators within the W51 complex and provide new insights into the origin of Galactic CRs. © 2024 Science China Press

关键词： Cosmic rays

STCF conceptual design report (Volume 1): Physics & detector

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of physics 2024年第1期19卷 1-154页

作者： M.Achasov X.C.Ai l.P.An R.Aliberti q.An X.Z.Bai Y.Bai O.Bakina A.Barnyakov V.Blinov V.Bobrovnikov d.Bodrov A.Bogomyagkov A.Bondar I.Boyko Z.h.Bu F.M.Cai h.Cai J.J.Cao q.h.Cao X.Cao Z.Cao q.Chang K.T.Chao d.Y.Chen h.Chen h.X.Chen J.F.Chen K.Chen l.l.Chen P.Chen S.l.Chen S.M.Chen S.Chen S.P.Chen W.Chen X.Chen X.F.Chen X.R.Chen Y.Chen Y.q.Chen h.Y.Cheng J.Cheng S.Cheng T.G.Cheng J.P.dai l.Y.dai X.C.dai d.dedovich A.denig I.denisenko J.M.dias d.Z.ding l.Y.dong W.h.dong V.druzhinin d.S.du Y.J.du Z.G.du l.M.duan d.Epifanov Y.l.Fan S.S.Fang Z.J.Fang G.Fedotovich C.q.Feng X.Feng Y.T.Feng J.l.Fu J.Gao Y.N.Gao P.S.Ge C.q.Geng l.S.Geng A.Gilman l.Gong T.Gong B.Gou W.Gradl J.l.Gu A.Guevara l.C.Gui A.q.Guo F.K.Guo J.C.Guo J.Guo Y.P.Guo Z.h.Guo A.Guskov K.l.han l.han M.han X.q.hao J.B.he S.q.he X.G.he Y.l.he Z.B.he Z.X.heng B.l.hou T.J.hou Y.R.hou C.Y.hu h.M.hu K.hu R.J.hu W.h.hu X.h.hu Y.C.hu J.hua G.S.huang J.S.huang M.huang q.Y.huang W.q.huang X.T.huang X.J.huang Y.B.huang Y.S.huang N.hüsken V.Ivanov q.P.Ji J.J.Jia S.Jia Z.K.Jia h.B.Jiang J.Jiang S.Z.Jiang J.B.Jiao Z.Jiao h.J.Jing X.l.Kang X.S.Kang B.C.Ke M.Kenzie A.Khoukaz I.Koop E.Kravchenko A.Kuzmin Y.lei E.levichev C.h.li C.li d.Y.li F.li G.li G.li h.B.li h.li h.N.li h.J.li h.l.li J.M.li J.li l.li l.li l.Y.li N.li P.R.li R.h.li S.li T.li W.J.li X.li X.h.li X.q.li X.h.li Y.li Y.Y.li Z.J.li h.liang J.h.liang Y.T.liang G.R.liao l.Z.liao Y.liao C.X.lin d.X.lin X.S.lin B.J.liu C.W.liu d.liu F.liu G.M.liu h.B.liu J.liu J.J.liu J.B.liu K.liu K.Y.liu K.liu l.liu q.liu S.B.liu T.liu X.liu Y.W.liu Y.liu Y.l.liu Z.q.liu Z.Y.liu Z.W.liu I.logashenko Y.long C.G.lu J.X.lu N.lu q.F.lü Y.lu Y.lu Z.lu P.lukin F.J.luo T.luo X.F.luo Y.h.luo h.J.lyu X.R.lyu J.P.Ma P.Ma Y.Ma Y.M.Ma F.Maas S.Malde d.Matvienko Z.X.Meng R.Mitchell A.Nefediev Y.Nefedov S.l.Olsen q.Ouyang P.Pakhlov G.Pakhlova X.Pan Y.Pan E.Passemar Y.P.Pei h.P.Peng l.Peng X.Y.Peng X.J.Peng K.Peters S.Pivovarov E.Pyata B.B.qi Y.q.qi W.B.qian Y.qian C.F.qiao J.J.qin J.J.qin l.q.qin X.S.qin T.l.qiu J.Rademacker C.F.Redmer h.Y.Sang Anhui University Hefei 230039China Beihang University Beijing 100191China Budker Institute of Nuclear Physics Novosibirsk 630090Russia CAS Key laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China Cavendish laboratory University of CambridgeJJ Thomson AveCambridge CB30HEUnited Kingdom Central China Normal University Wuhan 430079China Central South University Changsha 410083China China University of Geosciences Wuhan 430074China China University of Mining and Technology Xuzhou 221116China École Polytechnique Fédérale de lausanne(EPFl) LausanneSwitzerland Fudan University Shanghai 200433China Goethe University Frankfurt D-60325 Frankfurt am MainGermany Guangxi Normal University Guilin 541004China Guangxi Uninversity Nanning 530004China hangzhou Institute for Advanced Study UCASHangzhou 310024China hebei Normal University Shijiazhuang 050024China hebei University Baoding 071002China hefei University of Technology Hefei 230601China helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany henan Normal University Xinxiang 453007China henan University Kaifeng 475004China high Energy Physics Center Chung-Ang UniversitySeoul 06974Korea higher School of Economy 11 Pokrovsky Bulvar Moscow 109028Russia huangshan University Huangshan 245000China hubei University of Automotive Technology Shiyan 442002China hunan Normal University Changsha 410081China hunan University of Science and Technology Xiangtan 411201China hunan University Changsha 410082China Indiana University BloomingtonIndiana 47405USA Inner Mongolia University Hohhot 010021China Institute of Advanced Science Facilities Shenzhen 518107China Institute of high Energy Physics Chinese Academy of SciencesBeijing 100049China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China Institute of Physics Academia SinicaTaipeiTaiwan 11529China Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100190China Jilin University Changch

The superτ-charm facility(STCF)is an electron–positron collider proposed by the Chinese particle physics *** is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of 0.5×10^(35) cm^(–2)·s^(–1) or *** STCF will produce a data sample about a factor of 100 larger than that of the presentτ-charm factory—the BEPCII,providing a unique platform for exploring the asymmetry of matter-antimatter(charge-parity violation),in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions,as well as searching for exotic hadrons and physics beyond the Standard *** STCF project in China is under development with an extensive R&d *** document presents the physics opportunities at the STCF,describes conceptual designs of the STCF detector system,and discusses future plans for detector R&d and physics case studies.

关键词： electron–positron collider tau-charm region high luminosity STCF detector conceptual design

The reformation of catalyst:From a trial-and-error synthesis to rational design

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2024年第4期17卷 3261-3301页

作者： ligang Wang Jiabin Wu Shunwu Wang huan liu Yao Wang dingsheng Wang department of Chemistry Tsinghua UniversityBeijing 100084China

The appropriate catalysts can accelerate the reaction rate and effectively boost the efficient conversion of various molecules,which is of great importance in the study of chemistry,chemical industry,energy,materials and environmental ***,efficient,environmentally friendly,and easy to operate synthesis methods have been used to prepare various types of *** previous studies have reported the synthesis and characterization of the aforementioned catalysts,more still remain in trial and error methods,without in-depth consideration and improvement of traditional synthesis ***,we comprehensively summarize and compare the preparation methods of the trial-and-error synthesis strategy,structure–activity relationships and density functional theory(dFT)guided catalysts rational design for nanomaterials and atomically dispersed *** also discuss in detail the utilization of the nanomaterials and single atom catalysts for converting small molecules(h_(2)O,O_(2),CO_(2),N_(2),etc.)into value-added products driven by electrocatalysis,photocatalysis,and ***,the challenges and outlooks of mass preparation and production of efficient and green catalysts through conventional trial and error synthesis and dFT theory are featured in accordance with its current development.

关键词： trial-and-error synthesis structure–activity relationships density functional theory(dFT)guidance nanomaterials atomically dispersed catalysts

Carbon steel anticorrosion performance and mechanism of sodium lignosulfonate

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rare Metals 2024年第1期43卷 356-365页

作者： Bo-Kai liao Rui-Xuan quan Ping-Xian Feng huan Wang Wei Wang li Niu School of Chemistry and Chemical Engineering Guangzhou Key Laboratory of Sensing Materials and DevicesJoint Institute of Guangzhou University and Institute of Corrosion Science and TechnologyGuangzhou UniversityGuangzhou 510006China

lignin is a typical biological macromolecule with a three-dimensional network structure and abundant functional groups. It has excellent ionic complexation ability and amphiphilic molecular structure *** this study, the carbon steel anticorrosion performance of sodium lignosulfonate(SlS) in an acid solution was evaluated using the weight loss method, electrochemical measurements, scanning vibration electrode technique(SVET), and surface characterization methods. SlS exhibited excellent corrosion inhibition efficiency for q235carbon steel in 1 mol·l^(-1) hCl, reaching a maximum value of 98%. A low SlS concentration of 20 mg·l^(-1) resulted in the maximum corrosion inhibition efficiency, which remained nearly constant at higher SlS *** SVET test demonstrated that the formation of an SlS adsorption film can impede corrosion. This study confirms the significance of the application of green biomass resources in the field of metal corrosion protection and green functional materials.

关键词： lignin Sodium lignosulfonate Corrosion inhibitor Carbon Steel

Ab initio valence-space in-medium similarity renormalization group calculations for neutron-rich P,Cl,and K isotopes

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Chinese Physics C 2024年第7期48卷 181-190页

作者：谢萌冉沈留媛李健国李红蕙袁琪左维 Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China

Neutron-rich P,Cl,and K isotopes,particularly those with neutron numbers of approximately N=28,have attracted extensive experimental and theoretical *** utilize the ab initio valence-space in-medium similarity renormalization group approach,based on chiral nucleon-nucleon and three-nucleon forces,to investigate the exotic properties of these *** calculations of the low-lying spectra are performed.A key finding is the level inversion between 3/2_(1)^(+)and 1/2_(1)^(+)states in odd-A isotopes,attributed to the inversion ofπ0xod_(3/2) andπls_(1/2) single-particle *** ab initio calculations,which incorporate the three-nucleon forces,correlate closely with existing experimental *** calculations of effective proton single-particle energies provide deeper insights into the shell evolution for Z=14 and 16 *** results indicate that the three-body force plays important roles in the shell evolution for Z=14 and 16 sub-shells with neutron numbers ranging from 20 to ***,systematic ab initio calculations are conducted for the low-lying spectra of odd-odd *** results correspond with experimental data and provide new insights for future research into these isotopes up to and beyond the drip line.

关键词： ab initio calculations shell evolution low-lying spectra

由超拍电子伏特加速器产生的超高能伽马射线气泡

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science Bulletin 2024年第4期69卷 449-457页

作者： lhAASO Collaboration Zhen Cao Chuandong Gao Cong li Ruo-Yu liu Ruizhi Yang 不详 Key laboratory of Particle Astrophyics&Experimental Physics division&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China TIANFU Cosmic Ray Research Center ChengduChina Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237China School of Astronomy and Space Science Nanjing UniversityNanjing 210023China University of Science and Technology of China Hefei 230026China

We report the detection of aγ-ray bubble spanning at least 100deg2 in ultra-high energy(UhE)up to a few PeV in the direction of the star-forming region Cygnus X,implying the presence super PeVatron(s)accelerating protons to at least 10 PeV.A log-parabola form with the photon indexΓ(E)=(2.71±0.02)+(0.11±0.02)×log10(E/10 TeV)is found fitting the gamma-ray energy spectrum of the bubble *** sources,“hot spots”correlated with very massive molecular clouds,and a quasi-spherical amorphousγ-ray emitter with a sharp central brightening are observed in the *** the core of~0.5°,spatially associating with a region containing massive OB association(Cygnus OB2)and a microquasar(Cygnus X-3),as well as previously reported multi-TeV sources,an enhanced concentration of UhEγ-rays is observed with 2 photons at energies above 1 *** general feature of the bubble,the morphology,and the energy spectrum,are reasonably reproduced by the assumption of a particle accelerator in the core,continuously injecting protons into the ambient medium.

关键词： Cosmic rays γ-rays Interstellar medium Star cluster

leaching behavior and microstructure of phosphorus in converter slag

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2024年第7期31卷 1646-1660页

作者： Chao-gang Zhou Jin-yue li qing-gong Chen Yin-ye Yang Wei Gong li-qun Ai Shu-huan Wang Bei-yue Ma College of Metallurgy and Energy North China University of Science and TechnologyTangshan 063210HebeiChina Key laboratory for Ferrous Metallurgy and Resources Utilization of Ministry of Education Wuhan University of Science and TechnologyWuhan 430081HubeiChina College of Materials Science and Engineering Guizhou Minzu UniversityGuiyang 550025GuizhouChina School of Materials and Architectural Engineering Guizhou Normal UniversityGuiyang 550025GuizhouChina School of Metallurgy Northeastern UniversityShenyang 110819LiaoningChina

Converter slag is a by-product of the steelmaking process and contains a large amount of Ca,Fe,P and other *** the phosphorus in the converter slag can be effectively extracted,the resulting phosphorus can be used as a phosphate *** in converter slag is mainly enriched in 2CaO·SiO_(2)-3CaO·P_(2)O_(5)(C_(2)S-C_(3)P)solid solution and is easily dissolved in ***,acid leaching method was used to dissolve the solid solution to extract phosphorus in converter slag,so as to realize the recycling of phosphorus resources in converter *** leaching behavior of three actual converter slags from different steel mills in acid leaching solutions composed of citric acid,sodium hydroxide,hydrochloric acid and deionized water was studied by X-ray diffraction,scanning electron microscopy combined with energy dispersive spectrometry,Fourier transform infrared spectroscopy and Raman spectroscopy to reveal the change in object image structure as well as SiO_(4) and PO_(4) tetrahedron before and after acid *** results show that only a small amount of phosphorus in converter slag with too low basicity is enriched in C_(2)S-C_(3)P solid solution,resulting in poor leaching *** the converter slag has a high basicity,the removal effect of phosphorus is 70.64%-81.88%.In addition,when the basicity of converter slag is roughly the same,the dephosphorization effect of slag with high FeO content is relatively *** acid leaching will cause depolymerization behavior of SiO_(4) and PO_(4) tetrahedron,so that the mole fraction of q0(Si)(asymmetric stretching vibration of Si-O bond in SiO_(4) tetrahedron with bridge oxygen number of 0)and NBO/Si(non-bridging oxygen in silicate tetrahedra)will ***-containing solids can be obtained from the solution after acid leaching through static precipitation,and the solids have the potential to make phosphate fertilizers.

关键词： dephosphorization converter slag Acid leaching Phosphorus Solid solution Slag structure

Optimization of performance of the KM2A full array using the Crab Nebula

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics C 2024年第6期48卷 169-178页

作者：曹臻 F.Aharonian 安琪阿西克古白云翔包逸炜 d.Bastieri 毕效军毕玉江蔡金庭曹晴曹文羽曹喆常进常劲帆陈尚明陈恩生陈亮陈林陈龙陈明君陈玛丽陈起辉陈素弘陈天禄陈阳程宁程耀东崔明阳崔树旺崔晓红崔昱东戴本忠代洪亮戴子高单增罗布 d.della Volpe 董绪强段凯凯樊军辉范一中方军方堃冯存峰封莉冯少辉丰晓婷冯有亮 S.Gabici 高博高川东高林青高启高卫高伟康葛茂茂耿利斯 G.Giacinti 龚光华苟全补顾旻皓郭福来郭晓磊郭义庆郭莹莹韩毅昂何会海贺昊宁何佳银何新波何钰 M.heller 贺远强侯博文侯超侯贤胡红波胡铨胡世聪黄代绘黄天奇黄文俊黄性涛黄晓渊黄勇黄志成季筱璐贾焕玉贾康江琨姜晓巍姜泽军金敏康明铭柯通 d.Kuleshov.K.Kurinov 李兵兵李澄李骢李丹李飞李海波李会财李华阳李军李剑李捷李凯李文龙李文莲李秀荣李昕李一卓李哲黎卓梁恩维梁云峰林苏杰刘冰刘成刘栋刘虎刘海东刘佳刘江来刘金艳刘茂元柳若愚刘四明刘伟刘怡刘以农鲁睿罗晴吕洪魁马伯强马玲玲马欣华毛基荣闵振 W.Mitthumsiri 穆慧君南云程 A.Neronov 区子维庞彬宇 P.Pattarakijwanich 裴致远齐孟尧祁业情乔冰强秦家军 d.Ruffolo A.Sáiz d.Semikoz 邵澄宇邵琅 O.Shchegolev 盛祥东舒富文宋慧超 Yu.V.Stenkin V.Stepanov 苏扬孙秦宁孙晓娜孙志斌谭柏轩唐庆文唐泽波田文武王超王昌贝王广威王洪光王惠惠王建成汪凯王利苹王玲玉王培汉王冉王为王祥高王祥玉王阳王玉东王岩谨王忠海王仲翔王振王铮韦大明魏俊杰魏永健文韬吴超勇吴含荣武莎吴雪峰吴雨生席邵强夏捷夏君集项光漫肖迪泫肖刚辛广广辛玉良邢祎熊峥徐东莲徐仁峰徐仁新徐伟立薛良闫大海颜景志颜田杨朝文杨帆杨冯帆杨何文杨佳盈杨莉莉杨明洁杨睿智杨深邦姚玉华姚志国叶一锰尹丽巧尹娜游晓浩游智勇于艳红袁强岳华曾厚敦曾婷轩曾玮查敏张彬彬张丰张海明张恒英张建立张丽霞张力张鹏飞张佩佩张瑞张少博张少如张寿山张潇张笑鹏张云峰张毅张勇赵兵赵静赵雷赵立志赵世平郑福周斌周浩周佳能周猛周平周荣周勋秀祝成光祝凤荣朱辉朱科军左雄 lhAASO Collaboration Key laboratory of Particle Astrophyics&Experimental Physics division&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China Tianfu Cosmic Ray Research Center Chengdu 610000China dublin Institute for Advanced Studies 31 Fitzwilliam Place2 DublinIreland Max-Planck-Institut for Nuclear Physics P.O.Box 10398069029 HeidelbergGermany State Key laboratory of Particle detection and Electronics China University of Science and Technology of China Hefei 230026China School of Physical Science and Technology&School of Information Science and Technology Southwest Jiaotong UniversityChengdu 610031China School of Astronomy and Space Science Nanjing UniversityNanjing 210023China Center for Astrophysics Guangzhou UniversityGuangzhou 510006China hebei Normal University Shijiazhuang 050024China Key laboratory of dark Matter and Space Astronomy&Key laboratory of Radio Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China Tsung-dao lee Institute&School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China Key laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China Key laboratory of Cosmic Rays(Tibet University) Ministry of EducationLhasa 850000TibetChina National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China School of Physics and Astronomy(Zhuhai)&School of Physics(Guangzhou)&Sino-French Institute of Nuclear Engineering and Technology(Zhuhai) Sun Yat-sen UniversityZhuhai 519000&Guangzhou 510275China School of Physics and Astronomy Yunnan UniversityKunming 650091China département de Physique Nucléaire et Corpusculaire Facultéde SciencesUniversitéde Genève24 Quai Ernest Ansermet1211 GenevaSwitzerland Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237China APC Universit'e Paris Cit'eCNRS/IN2P3CEA/IRFUObservat

The full array of the large high Altitude Air Shower Observatory(lhAASO)has been in operation since July *** its kilometer-square array(KM2A),we optimized the selection criteria for very high and ultrahigh energyγ-rays using data collected from August 2021 to August 2022,resulting in an improvement in significance of the detection in the Crab Nebula of approximately 15%,compared with that of previous *** the implementation of these new selection criteria,the angular resolution was also significantly improved by approximately 10%at tens of *** aspects of the full KM2A array performance,such as the pointing error,were also calibrated using the Crab *** resulting energy spectrum of the Crab Nebula in the energy range of 10-1000 TeV are well fitted by a log-parabola model,which is consistent with the previous results from lhAASO and other experiments.

关键词： γ-ray Crab Nebula significance

Jianpi decoction Combined with Medroxyprogesterone Acetate Alleviates Cancer Cachexia and Prevents Muscle Atrophy by directly Inhibiting E3 Ubiquitin ligase

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Integrative Medicine 2024年第6期30卷 499-506页

作者： lI qi KONG Zhao-di WANG huan GU hong-hui ChEN Zhong li Shi-guang ChEN Yi-qi CAI Yu YANG Zhen-jiang department of Oncology and hematology Shenzhen Traditional Chinese Medicine HospitalShenzhenGuangdong Province518033China College of Pharmacy/International Cooperative laboratory of Traditional Chinese Medicine Modernization and Innovative drug development of Ministry of Education(MOE)of China Jinan UniversityGuangzhou510632China Guangdong Key lab of Traditional Chinese Medicine Information Technology Jinan UniversityGuangzhou510632China

ObjectiveTo provide comprehensive evidence for the anti-cancer cachexia effect of Jianpi decoction(JP)and to explore its mechanism of anti-cancer *** mouse model of colon cancer(CT26)-induced cancer cachexia(CC)was used to investigate the anti-CC effect of JP combined with medroxyprogesterone acetate(MPA).Thirty-six mice were equally divided into 6 groups:normal control,CC,MPA(100 mg·kg^(−1)·d^(−1)),MPA+low-dose(20 mg·kg^(−1)·d^(−1))JP(l-JP),MPA+medium-dose(30 mg·kg^(−1)·d^(−1))JP(M-JP),and MPA+high-dose(40 mg·kg^(−1)·d^(−1))JP(h-JP)*** successful modeling,the mice were administered by gavage for 11 *** body weight and tumor volume were measured and recorded every 2 d starting on the 8th day after *** liver,heart,spleen,lung,kidney,tumor and gastrocnemius muscle of mice were collected and *** pathological changes of the tumor was observed,and the cross-sectional area of the gastrocnemius muscle was *** protein expressions of STAT3 and E3 ubiquitinase in the gastrocnemius muscle were measured by Western *** addition,an in vitro C2C12 myotube formation model was established to investigate the role of JP in hindering dexamethasone-induced muscle *** vitro experiments were divided into control,model,and JP serum *** 2-d administration,microscopic photographs were taken and myotube diameters were *** blot was performed to measure the protein expressions of STAT3 and E3 *** combined with MPA restored tumor-induced weight loss(Pd muscle fiber size(Phanistically,JP reduced the expression of atrophy-related proteins MuRF1 and MAFbx in tumor-induced muscle atrophy in vivo(Pddition,JP reduced the expression of atrophy-related proteins MuRF1 and MAFbx and p-STAT3 phosphorylation(Pd with dexamethasone in *** of JP combined with MPA restores t

关键词： cancer cachexia muscle atrophy Jianpi decoction Chinese medicine E3 ubiquitin ligases