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does a large prostate size,small lesion volume,or long needle distance from the probe to the lesion reduce ma.netic resonance imaging–targeted cancer detection?

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Current Urology 2024年第2期18卷 144-147页

作者： Mark d.Bevill Justin n.drobish Kevin J.Flynn Maheen Rajput Catherine Metz Chad R.Tracy Paul T.gellhaus department of Urology University of Iowa Carver College of MedicineIowa CityIAUSA department of Radiology University of Iowa Carver College of MedicineIowa CityIAUSA

Background:We aimed to evaluate whether large prostate size,small lesion volume,or long lesion distance from the ultrasound probe tip would decrease cancer detection in transrectal ma.netic resonance imaging(MRI)–targeted *** and methods:Patients who underwent MRI-targeted biopsy at our institution between May 2017 and August 2019 were enrolled in a prospective *** to 5 cores were obta.ned from≥2 prostate imaging reporting and data system v2 lesions.A multivariable model was created that included needle distance to the lesion,prostate specific antigen,prostate imaging reporting and data system,lesion volume,and prostate ***:A total of 377 patients with 533 lesions underwent a biopsy during the study period.A total of 233(44%)lesions were positive for prostate cancer,and 173(32%)lesions had clinically significant prostate *** mean needle distance to the lesion was 11.7mm(interquartile range,7.6–15.5mm).The likelihood of obta.ning a positive core on biopsy decreased as the distance fromthe ultrasound probe increased for all prostate cancers and clinically significant prostate cancer(p=0.018 and p=0.004,respectively).Every 10mmfrom the rectum,there was an 8%–10%decrease in the rate of cancer ***,as the prostate volume increased,the odds of obta.ning a positive core also decreased(p=0.039).There was no significant association between the lesion size and amount of cancer obta.ned on ***:Our data showed that transrectal MRI-targeted biopsy cancer detection modestly decreased the lesion from the ultrasound probe and with a large prostate volume but could not prove that lesion volume was a significant predictor of the amount of cancer detected.

关键词： Prostate cancer Biopsy Ma.netic resonance imaging

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Are population cycles recovering?

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Integrative Zoology 2024年第3期19卷 538-547页

作者： Vasily d.YAKUSHOV Boris I.SHEFTEL a.n.Severtsov Institute of Ecology and Evolution of the Russian Academy of Sciences MoscowRussia

The dynamics of populations of small mammals of Central Siberia was *** studies were carried out at the Yenisei ecological station“Mirnoye”of the *** Institute of Ecology and Evolution,Russian Academy of *** time series analysis was performed by the wavelet transform using the statistical data processing language *** the 20th century,the dynamics of the population of the community and some of its constituent species(Sorex araneus;***;***;***;***;Craseomys rufocanus;Clethrionomys rutilus;Microtus oeconomus;***)were characterized by a 4-year *** type of dynamics changed to noncyclic by the nineties,but by 2022,four species(***,***,***,and ***)and the community as a whole showed a tendency toward recovery of population *** rema.ning species were characterized by consistently low numbers with irregular low amplitude fluctuations.

关键词： population cycles small mammals time-series analysis wavelet transform

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MXetronics-MXene电子学

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无机材料学报 2024年第2期39卷 171-178页

作者：徐向明 Husam n ALSHAREEF 阿卜杜拉国王科技大学沙特阿拉伯图瓦23955-6900

超薄的过渡金属碳氮化合物MXenes,作为一大类新兴二维(2d)材料,是当前材料研究热点方向之一。自2d材料发现至今已有近20年,以石墨烯、过渡金属硫族化合物、黑磷等为代表的2d材料在微纳电子领域经历了相对广泛且深入的研究,MXenes自2011... 详细信息

超薄的过渡金属碳氮化合物MXenes,作为一大类新兴二维(2d)材料,是当前材料研究热点方向之一。自2d材料发现至今已有近20年,以石墨烯、过渡金属硫族化合物、黑磷等为代表的2d材料在微纳电子领域经历了相对广泛且深入的研究,MXenes自2011年诞生以来在微纳电子领域的研究也方兴未艾。MXenes拥有丰富的元素结构组成和独特的物理化学特性(表面亲水性、功函可调、官能团可调、电和离子快速传输特性、表面离子激元、光热电、电磁吸收等),使其在微纳电子领域具有潜在的应用前景。Alshareef课题组近几年致力于将MXene引入到微纳电子领域,并在2019年用MXetronics来定义MXene电子学这一新兴的学术领域。本文简要总结和评价了该领域的代表性进展,梳理了包括微电子级的合成、加工、物性探索和器件应用等方面面临的挑战,最后指出一些关键的研究方向和尚未探索的细分领域。

关键词： MXenes 微纳电子薄膜微纳加工合成晶体管专题评述

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Multifunctional SnO_(2) Qds/MXene Heterostructures as Laminar Interlayers for Improved Polysulfide Conversion and Lithium Plating Behavior

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nano-Micro Letters 2024年第11期16卷 156-169页

作者： Shungui deng Weiwei Sun Jiawei Tang Mohammad Jafarpour Frank nüesch Jakob Heier Chuanfang Zhang College of Materials Science and Engineering Sichuan UniversityChengdu 610065People’s Republic of China Laboratory for Functional Polymers Swiss Federal Laboratories for Materials Science and Technology(EMPA)Überlandstrasse 1298600 DübendorfSwitzerland Institute of Materials Science and Engineering Ecole Polytechnique Fédérale de Lausanne(EPFL)Station 121015 LausanneSwitzerland Key Laboratory of Quantum Materials and devices of Ministry of Education School of PhysicsSoutheast UniversityNanjing 211189People’s Republic of China SEU‑FEI nano‑Pico Center Key Laboratory of MEMS of Ministry of EducationSoutheast UniversityNanjing 210096People’s Republic of China

Poor cycling stability in lithium–sulfur(Li–S)batteries necessitates advanced electrode/electrolyte design and innovative interlayer *** catalysis has emerged as a promising approach,leveraging the adsorption and catalytic performance on lithium polysulfides(LiPSs)to inhibit LiPSs shuttling and improve redox *** this study,we report an ultrathin and laminar SnO_(2)@MXene heterostructure interlayer(SnO_(2)@MX),where SnO_(2) quantum dots(Qds)are uniformly distributed across the MXene *** combined structure of SnO_(2) Qds and MXene,along with the creation of numerous active boundary sites with coordination electron environments,plays a critical role in manipulating the catalytic kinetics of sulfur *** Li–S cell with the SnO_(2)@MX-modified separator not only demonstrates superior electrochemical performance compared to cells with a bare separator but also induces homogeneous Li deposition during *** a result,an areal capacity of 7.6 mAh cm^(-2) under a sulfur loading of 7.5 mg cm^(-2) and a high stability over 500 cycles are *** work demonstrates a feasible strategy of utilizing a laminar separator interlayer for advanced Li–S batteries awaiting commercialization and may shed light on the understanding of heterostructure catalysis with enhanced reaction kinetics.

关键词： Lithium-sulfur battery Heterogeneous catalysis Heterostructure Redox kinetics Lithium dendrites

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Validation of the TOPAS Monte-Carlo Code of the Off-Field dose of a 6 MV Synergy Linac

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Journal of Biosciences and Medicines 2024年第7期12卷 38-54页

作者： Kodjo Joel Fabrice n’guessan Ibrahima Sakho Bogbé d. L. H. gogon department of Physics and Chemistry Faculty of Sciences and Technology Iba Der Thiam University of This This Senegal International Cancer Center of dakar Dakar Senegal department of Physics Faculty of Sciences and Technology Flix Houphouet Boigny University of Abidjan Abidjan Cte dIvoire

The risk of radiation-induced second cancer and the late tissue loss due to Off-field doses in radiotherapy rema.n a serious concern. Monte Carlo (MC) simulation is currently one of the most accurate methods for calculating these doses. MC simulation model based on the Particle Simulation Tool (TOPAS) has been developed to simulate the off-field dose of an Elekta Synergy linear accelerator (Linac) emitting 6 MV photons. Measurements were taken in a water phantom using an ionization chamber to validate this model. The Percentage depth dose (Pdd) at the depth of 0.0, 5.0, 10.0 and 15.0 cm from the beam axis for a 10 × 10 cm2 field size was measured and simulated. Off-field dose profiles at the depth of 1.5 (dmax), 5.0 and 10.0 cm for field sizes of 5 × 5, 10 × 10, 15 × 15, and 20 × 20 cm2 respectively were measured and simulated. Comparison of measured and simulated off-field dose values showed a good agreement. The average gamma passing rate of the Pdds and profiles curves for off-field doses were 87.5% and 98.11% respectively. The local dose difference based on the Pdd curve between the measured and simulated was less than 6.0 % for all locations. For all field size considered in this study, the average difference between profile curves for off-field dose measured and simulated was 9.1%. Pdds and Profiles curves for off-field dose simulation uncerta.nties were less than 2.0% and 1.0% respectively. TOPAS-MC simulation model developed is a good representation of our 6 MV Linac Elekta Synergy for assessing off-field dose, which would be the primary cause of some secondary cancers.

关键词： Radiotherapy Off-Field dose Secondary Cancer TOPAS-MC Simulation dosimetry

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Previously undia.nosed Morga.ni hernia with bowel perforation detected during repeat screening colonoscopy: A case report

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World Journal of Clinical Cases 2024年第14期12卷 2389-2395页

作者： Said Al Alawi Alan n Barkun Sara.najmeh division of gastroenterology McGill UniversityMontrealQC H4A 3J1Canada division of Thoracic surgery McGill UniversityMontrealQC H4A 3J1Canada

BACKgROUnd Morga.ni hernia(MH)is a form of congenital diaphragmatic hernia(CdH)characterized by an incomplete formation of diaphragm,resulting in the protru-sion of abdominal organs into the thoracic *** estimated incidence of CdH is between 1 in 2000 and 1 in 5000 live births,although the true incidence is *** typically presents in childhood and can be dia.nosed either pre-natally or ***,it can also be asymptomatic and carry the risk of developing into a life-threatening condition in *** SUMMARY A 76-year-old female with no history of prior abdominal surgeries presented for an elective colonoscopy for polyp *** the procedure,when approaching the hepatic flexure,the scope could not be advanced further despite multiple *** patient experienced mild abdominal discomfort,leading to the abortion of the *** in the recovery area,she developed increa-sing abdominal pa.ns and *** abdominal imaging revealed her-niation of the proximal transverse colon through a MH into the chest with evi-dence of *** patient underwent laparoscopic urgent colonic resection and primary hernia repair and was discharged uneventfully 2 d *** A MH is a rare condition in adults that can present as a life-threatening compli-cation of colonoscopy,even in patients with a history of uneventful *** case highlights the importance of considering congenital and internal hernias when faced with sudden and unexpla.ned difficulties during *** there is a suspicion of MH,the endoscopist should halt the procedure and immediately obta.n abdominal imaging to confirm the dia.nosis.

关键词： Bowel perforation Colonoscopy Adverse event Congenital diaphragmatic

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Enabling Technologies for Autonomous Robotic Systems in Manufacturing

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Transactions of nanjing University of Aeronautics and Astronautics 2024年第4期41卷 403-431页

作者： ERdŐS gábor ABAI Kristóf BEREgI Richárd CSEMPESZ János CSERTEg Tamás gOd.g.bor HAJÓS Mátyás HÁY Borbála HORVÁTH dániel HORVÁTH gergely JUnIKIÁdám KEMÉnY Zsolt KOVÁCS András nACSA János PAnITI Imre PEdOnE gianfranco TAKÁCS Emma TIPARY Bence ZAHORÁn László VÁnCZA József Institute for Computer Science and Control Hungarian Research Network(HUN-REN SZTAKI)BudapestHungary department of Manufacturing Science and Technology Budapest University of Technology and Economics(BME)BudapestHungary EPIC InnoLabs nonprofit Ltd. BudapestHungary Eötvös Loránd University(ELTE) BudapestHungary

Research of autonomous manufacturing systems is motivated both by the new technical possibilities of cyber-physical systems and by the practical needs of the *** operation in semi-structured industrial environments can now be supported by advanced sensor technologies,d.g.tal twins,artificial intelligence and novel communication *** enable real-time monitoring of production processes,situation recognition and prediction,automated and adaptive(re)pla.ning,teamwork and performance improvement by *** paper summarizes the ma.n requirements towards autonomous industrial robotics and suggests a generic workflow for realizing such *** case studies will be presented from recent practice at HUn-REn SZTAKI in a broad range of doma.ns such as assembly,welding,grinding,picking and placing,and *** various solutions have in common that they use a generic d.g.tal twin concept as their *** making general recommendations for realizing autonomous robotic solutions in the industry,open issues for future research will be discussed.

关键词： industrial robotics autonomy d.g.tal twin enabling technology

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Oligodendroctyes:the forgotten players of diabetes pathophysiology

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neural Regeneration Research 2024年第11期19卷 2349-2350页

作者： Juan Antonio López-Villodres Beatriz garcía-díaz departamento Fisiología Humana Histología HumanaAnatomía Patológica y Educación Física y DeportivaFacultad de MedicinaUniversidad de MálagaMálagaSpain UgC neurociencia.Instituto de Investigación Biomédica de Málaga y Plataforma en nanomedicina(IBIMA Plataforma Bionand) MálagaSpain

Oligodendrocytes(OLs),glial cells that provide myelin sheaths to axons in the central nervous system(CnS),have a dual ***,this myelin fatty cover around the axons protects the nerves and is crucial for the saltatory propagation of action *** and not less important,OLs provide trophic support to neurons and ***,OL metabolism is important for OL well-being and the proper accomplishment of their functions,and OL metabolism energetics directly affect the energy metabolism of neighboring neurons.

关键词： metabolism nerves myelin

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High CO_(2)permeation using a.new Ce_(0.85)gd_(0.15)O_(2-δ)-LaniO_(3)composite ceramic–carbonate dual-phase membrane

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Journal of Environmental Sciences 2024年第6期140卷 219-229页

作者： daniela gonzález-Varela JFrancisco gómez-garcía gustavo Tavizon Heriberto Pfeiffer Instituto de Investigaciones en Materiales Universidad Nacional Autónoma de MéxicoCd.UniversitariaDel.CoyoacánCP 04510Ciudad de MéxicoMéxico departamento de Física y Química Teórica Facultad de QuímicaUniversidad Nacional Autónoma de MéxicoCd.UniversitariaDel.CoyoacánCP 04510Ciudad de MéxicoMéxico 不详

This work shows the synthesis,characterization and evaluation of dense-ceramic membranes made of Ce_(0.85)gd_(0.15)O_(2-δ)-LaniO_(3)(Cg-Ln)composites,where the fluorite-perovskite ratio(Cg:Ln)was varied as follows:75:25,80:20 and 85:15 wt.%.Supports were initially characterized by XRd,SEM and electrical conductivity(using vacuum and oxygen atmospheres),to determine the composition,microstructural and ionic-electronic conductivity ***,supports were infiltrated with an eutectic carbonates mixture,producing the corresponding dense dual-phase membranes,in which CO_(2)permeation tests were ***,CO_(2)permeation experiments were performed from 900 to 700℃,in the presence and absence of oxygen(flowed in the sweep membrane side).Results showed that these composites possess high CO_(2)permeation properties,where the O_(2)addition significantly improves the ionic conduction on the sweep membrane ***,the gC80-Ln20 composition presented the best results due to the following physicochemical characteristics:high electronic and ionic conductivity,appropriate porosity,interconnected porous cha.nels,as well as thermal and chemical stabilities between the composite support and carbonate phases.

关键词： CO_(2)permeation doped CeO_(2) LaniO_(3) Impedance Ceramic carbonate membrane

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The interaction of the structure-directing agent with the zeolite framework determines germanium distribution in SCM-15 germanosilicate

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Frontiers of Chemical Science and Engineering 2024年第5期18卷 105-114页

作者： Stoyan P.gramatikov Petko St.Petkov Zhendong Wang Weimin Yang georgi n.Vayssilov Faculty of Chemistry and Pharmacy University of Sofia1126 SofiaBulgaria State Key Laboratory of green Chemical Engineering and Industrial Catalysis Sinopec Shanghai Research Institute of Petrochemical Technology Co.Ltd.Shanghai 201208China

We report results from computational modeling of the relative stability of germanosilicate SCM-15 structure due to different distribution of germanium heteroatoms in the double four-member rings(d4Rs)of the framework and the orientation of the structure directing agent(SdA)molecules in the as-synthesized *** calculated relative energies of the bare zeolite framework suggest that structures with germanium ions clustered in the same d4Rs,e.g.,with large number of ge–O-ge contacts,are the most *** simulations of various orientations of the SdA in the pores of the germanosilicate zeolite show different stability order-the most stable models are the structures with germanium spread among all ***,for SCM-15 the stabilization due to the presence of the SdA and their orientation,is thermodynamic factor directing both the formation of specific framework type and.g. distribution in the framework during the *** relative stability of bare structures with different germanium distribution is of minor *** differs from SCM-14 germanosilicate,reported earlier,for which the stability order is preserved in presence of ***,even for zeolites with the same chemical composition and SdA,the characteristics of their framework lead to different energetic preference for germanium distribution.

关键词： zeolite density functional theory structure-directing agent SCM-15

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