检索结果-南通市图书馆

Energy Geoscience 2021年第2期2卷 121-128页

作者： J.Ribeiro d.flores department of Earth Sciences University of CoimbraRua Silvio Lima3030-790CoimbraPortugal Institute of Earth Sciences-Porto Pole Rua Do Campo Alegre 6874169-007PortoPortugal Environment and Spatial Planning Department of GeosciencesUniversity of PortoRua Do Campo Alegre 6874169-007PortoPortugal

The coal mining residues from past mining activities in the douro Coalfield are emplaced in many dumps near the mining areas,causing substantial environmental *** study aims to contribute to the investigation of environmental impacts caused by the disposal of the residue in the douro Coalfield through the determination of the geochemical composition of waste materials collected at 3 e 15 m depth,and of the water-leachable fraction produced by percolation in these materials inside the *** elements with higher concentration in the leachates are Ca,Cd,Co,Mg,Mn,Na,Ni,S,and Zn,indicating that they are the most easily leached and accessible elements for percolation and mobilization into the *** presence of these elements in the leachates is principally attributed to their occurrence as water-soluble ions in clays and sulphides affected by natural weathering conditions,which promotes their breakdown and occurrence as exchangeable *** leachates are classified as acid *** weathering and leaching in the Sao Pedro da Cova waste dump are the principal~paths for chemical elements to be percolated and mobilized to environment,posing risk to the soils,waters and ecosystems in the surrounding areas.

关键词： Coal mining Waste dump Water-soluble compound Hazardous element

Acute Post-Activation Potentiation Effects of Heavy High-Pulls on Clean Performance

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Science in Sport and Exercise 2019年第3期1卷 257-263页

作者： Marisa K.Straughn Christopher C.dake Ludmila M.Cosio-Lima Cameron d.Addie Kyle B.Rank Sarai d.flores Lee E.Brown department of Movement Sciences and Health University of West Florida11000 University ParkwayPensacolaFL 32514USA

Aim The concept of post-activation potentiation(PAP)is still novel from a training perspective and lacks breadth relative to weightlifting *** The purpose of this study was to investigate the acute effects of a conditioning activity(clean high pulls)on the performance of a main activity(clean)after the conditioning *** Eleven volunteers who engaged in weightlifting(Male=5,Female=6)participated in two different testing ses-sions(experimental ***).Baseline measurements were taken following the *** testing condition was performed and additional measurements were taken at 30 s,2 min,4 min,6 min,8 min,10 min,and 12 min into recovery.A linear position transducer was used to collect peak power,peak velocity,and displacement of the barbell during the *** 2×8 repeated measures ANOVAs were used to analyze the data along with a paired samples t test between baseline and"best"*** There was no interaction or main effect for condition(P>0.05).However,there was a significant main effect for time(Pdisplacement:experimental=111.07 ± 12.09 cm *** 107.01 ± 11.32 cm).Conclusions The findings of this study are in partial agreement with previous literature where the warm-up was probably enough to elicit ***,recommendations for future studies could include utilizing a more elite population and to ensure all potential participants can squat at least 2 x their body weight.

关键词： Weightlifting Cleans Post-activation potentiation GymAware Linear positional transducer

dendritic spine degeneration:a primary mechanism in the aging process

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1696-1698页

作者： Gonzalo flores Leonardo Aguilar-Hernández Fernado García-dolores Humberto Nicolini Andrea Judith Vázquez-Hernández Hiram Tendilla-Beltrán Instituto de Fisiología Benemérita Universidad Autónoma de Puebla(BUAP)PueblaMexico Instituto de Ciencias Forenses(INCIFO) Tribunal Superior de Justicia de la Ciudad de México(TSJCDMX).Mexico CityMexico Instituto Nacional de Medicina Genómica(INMEGEN) Mexico CityMexico

Recent reports suggest that aging is not solely a physiological process in living beings;instead, it should be considered a pathological process or disease(Amorim et al., 2022). Consequently, this process involves a wide range of factors, spanning from genetic to environmental factors, and even includes the gut microbiome(GM)(Mayer et al., 2022). All these processes coincide at some point in the inflammatory process, oxidative stress, and apoptosis, at different degrees in various organs and systems that constitute a living organism(Mayer et al., 2022;AguilarHernández et al., 2023).

关键词： aging process stress

Neurotrophic fragments as therapeutic alternatives to ameliorate brain aging

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2023年第1期18卷 51-56页

作者： Itzel Ortiz flores Samuel Treviño Alfonso díaz department of Health Sciences School of MedicineUniversity of the Americas PueblaPueblaMexico Faculty of Chemical Sciences Benemerita Autonomous University of PueblaPueblaMexico

Aging is a global phenomenon and a complex biological process of all living beings that introduces various *** this physiological process,the brain is the most affected organ due to changes in its structural and chemical functions,such as changes in plasticity and decrease in the number,diameter,length,and branching of dendrites and dendritic ***,it presents a great reduction in volume resulting from the contraction of the gray ***,aging can affect not only cognitive functions,including learning and memory,but also the quality of life of older *** a result of the phenomena,various molecules with notable neuroprotective capacity have been proposed,which provide a therapeutic alternative for people under conditions of aging or some neurodegenerative *** is important to indicate that in recent years the use of molecules with neurotrophic activity has shown interesting results when evaluated in in vivo *** review aims to describe the neurotrophic potential of molecules such as resveratrol(3,5,4′-trihydroxystilbene),neurotrophins(brain-derived neurotrophic factor),and neurotrophic-type compounds such as the terminal carboxyl domain of the heavy chain of tetanus toxin,cerebrolysin,neuropeptide-12,and *** of these molecules have been evaluated by our research *** suggest that these molecules exert an important therapeutic potential,restoring brain function in aging conditions or models of neurodegenerative ***,our interest is in describing the current scientific evidence that supports the therapeutic potential of these molecules with active neurotrophic.

关键词： Alzheimer’s disease brain cerebral cortex cognitive function dendritic spines HC-TeTx hippocampus neurodegeneration neuronal survival neurotrophins

differential response of injured and healthy retinas to syngeneic and allogeneic transplantation of a clonal cell line of immortalized olfactory ensheathing glia:a double-edged sword

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第8期20卷 2395-2407页

作者： María Norte-Muñoz María Portela-Lomba Paloma Sobrado-Calvo diana Simón Johnny di Pierdomenico Alejandro Gallego-Ortega Mar Pérez JoséMCabrera-Maqueda Javier Sierra Manuel Vidal-Sanz María Teresa Moreno-flores Marta Agudo-Barriuso Grupo de Investigación Oftalmología Experimental Departamento de OftalmologíaOptometríaOtorrinolaringología y Anatomía PatológicaFacultad de MedicinaUniversidad de MurciaInstituto Murciano de Investigación Biosanitaria(IMIB)Campus de Ciencias de la SaludMurciaSpain Experimental Sciences Faculty Universidad Francisco de VitoriaPozuelo de AlarcónMadridSpain Anatomy Histology and Neuroscience DepartmentMedicine FacultyUniversidad Autónoma de MadridMadridSpain Center of Neuroimmunology Service of NeurologyLaboratory of Advanced Imaging in Neuroimmunological DiseasesHospital Clínic of BarcelonaInstitut d’Investigacions Biomèdiques August Pi i Sunyer(IDIBAPS)and Universitat de BarcelonaBarcelonaSpain Medicine Faculty Universidad Francisco de VitoriaPozuelo de AlarcónMadridSpain

Olfactory ensheathing glia promote axonal regeneration in the mammalian central nervous system,including retinal ganglion cell axonal growth through the injured optic ***,it is unknown whether olfactory ensheathing glia also have neuroprotective *** ensheathing glia express brain-derived neurotrophic factor,one of the best neuroprotectants for axotomized retinal ganglion ***,we aimed to investigate the neuroprotective capacity of olfactory ensheating glia after optic nerve *** ensheathing glia cells from an established rat immortalized clonal cell line,TEG3,were intravitreally injected in intact and axotomized retinas in syngeneic and allogeneic mode with or without microglial inhibition or immunosuppressive *** and gene expression analyses were *** bulb-derived primary olfactory ensheathing glia and TEG3 express major histocompatibility complex classⅡ*** and syngenically transplanted TEG3 cells survived in the vitreous for up to 21 days,forming an *** axotomized retinas,only the allogeneic TEG3 transplant rescued retinal ganglion cells at 7 days but not at 21 *** these retinas,microglial anatomical activation was higher than after optic nerve crush *** intact retinas,both transplants activated microglial cells and caused retinal ganglion cell death at 21 days,a loss that was higher after allotransplantation,triggered by pyroptosis and partially rescued by microglial inhibition or ***,neuroprotection of axotomized retinal ganglion cells did not improve with these *** different neuroprotective properties,different toxic effects,and different responses to microglial inhibitory treatments of olfactory ensheathing glia in the retina depending on the type of transplant highlight the importance of thorough preclinical studies to explore these variables.

关键词： cell therapy immune recognition major histocompatibility complex class II(MHCII) neuroprotection olfactory ensheathing glia retinal ganglion cells

Biochemical dissection of STAT3 signaling in amyotrophic lateral sclerosis

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第11期20卷 3229-3230页

作者： Savina Apolloni Nadia d’Ambrosi department of Biology University of Rome Tor VergataRomeItaly

Amyotrophic lateral sclerosis(ALS)is a progressive neurodegenerative disease characterized by the loss of upper and lower motor neurons,clinically marked by muscle atrophy and *** the clinical course is highly variable,the average time from the onset of symptoms to the need for respiratory support or death is 3-5 *** is the most prevalent motor neuron disease in adults,occurring at a rate of 2 per 100,000 individuals and affecting 5.4 per 100,000 individuals overall.

关键词： STAT3 dissection sclerosis

Ligand effects on the structure and vibrational properties of the thiolated Au18 cluster

在线全文

学校读者我要写书评

暂无评论

Progress in Natural Science:Materials International 2016年第5期26卷 510-515页

作者： Alfredo Tlahuice-flores CICFIM-Facultad de Ciencias Físico-Matemáticas Universidad Autónoma de Nuevo León

Most of the studies devoted to thiolated gold clusters suppose that their core and Au-S framework do not suffer from distortion independently of the protecting ligands（-SR） and it is assumed as correct to simplify the ligand as SCH3. In this work is delivered a systematic study of the structure and vibrational properties（IR and Raman）of the Au18（SR）14cluster. The pursued goal is to understand the dependency of the displayed vibrational properties of the thiolated Au18cluster with the ligands type. A set of six ligands was considered during calculations of the vibrational properties based on density functional theory（dFT） and in its dispersioncorrected approach（dFT-d）.

关键词： Gold cluster Ligand effects Structure Vibration Au18(SR)14 density functional theory

Anti-amyloid antibodies in Alzheimer’s disease: what did clinical trials teach us?

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第4期20卷 1092-1093页

作者： danko Jeremic Lydia Jiménez-díaz Juan d.Navarro-López NeuroPhysiology&Behavior Lab University of Castilla-La ManchaBiomedical Research Center(CRIB)School of Medicine of Ciudad RealCiudad RealSpain

Although many causes of Alzheimer’s disease(Ad)may exist,both the original amyloid cascade and tau hypotheses posit that abnormal misfolding and accumulation of amyloid-β(Aβ)and tau protein is the central event causing the ***,that conclusion could be only partly true,and there is conflicting evidence about the role of both proteins in Ad,being able to precede and influence one *** researchers argue that these proteins are mere executors rather than primary causes of ***,there have been continuing refinements of both hypotheses,with alternative explanations proposed.Aβand tau proteins may be independently involved in specific neurotoxic pathways;yet there may be other crucial processes going on in early ***,accumulating evidence suggests that Aβand tau act synergistically,rather than additively in disease onset(Jeremic et al.,2021,2023a).

关键词： amyloid Alzheimer additive

Curcuma longa L. extract improves the cortical neural connectivity during the aging process

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2017年第6期12卷 875-880页

作者： Gonzalo flores Laboratorio de Neuropsiquiatría Instituto de Fisiología Benemérita Universidad Autónoma de Puebla

Turmeric or Curcuma is a natural product that has anti-inflammatory, antioxidant and anti-apoptotic pharmacological properties. It can be used in the control of the aging process that involves oxidative stress, inflammation, and apoptosis. Aging is a physiological process that affects higher cortical and cognitive functions with a reduction in learning and memory, limited judgment and deficits in emotional control and social behavior. Moreover, aging is a major risk factor for the appearance of several disorders such as cerebrovascular disease, diabetes mellitus, and hypertension. At the brain level, the aging process alters the synaptic intercommunication by a reduction in the dendritic arbor as well as the number of the dendritic spine in the pyramidal neurons of the prefrontal cortex, hippocampus and basolateral amygdala, consequently reducing the size of these regions. The present review discusses the synaptic changes caused by the aging process and the neuroprotective role the Curcuma has through its anti-inflammatory, antioxidant and anti-apoptotic actions.

关键词： Curcuma longa cortical curcumin hippocampus synaptic antioxidant spine connectivity cortex

Remaking a connection:molecular players involved in post-injury synapse formation

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1719-1720页

作者： diogo Tomé Ramiro d.Almeida iBiMEd-Institute of Biomedicine Department of Medical SciencesUniversity of AveiroAveiroPortugal CNC-Center for Neuroscience and Cell Biology University of CoimbraCoimbraPortugal

Functional recovery from central nervous system(CNS)trauma depends not only on axon regeneration or compensatory sprouting of uninjured fibers but also on the ability of newly grown axons to establish functional synapses with appropriate *** several studies have successfully promoted long-distance axonal regeneration in distinct CNS injury models,none of them have resulted in a viable therapeutic approach for patient recovery.A possible reason may be the lack of new synaptogenesis for reestablishing the circuitry lost after ***,we discuss how our understanding of the mechanisms that instruct synapse formation in the injured nervous system may contribute to the design of new strategies to promote functional restoration in traumatic CNS disorders.

关键词： viable injury instru