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APSO-CNN-SE: An Adaptive Convolutional Neural Network Approach for IoT Intrusion detection

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Computers, Materials and Continua 2024年第1期81卷 567-601页

作者： Ban Y. Zhang d. He Q. Shen Q. College of Big data and Information Engineering Guizhou University Guizhou 550025 China

The surge in connected devices and massive data aggregation has expanded the scale of the Internet of Things (IoT) networks. The proliferation of unknown attacks and related risks, such as zero-day attacks and distributed denial of Service (ddoS) attacks triggered by botnets, have resulted in information leakage and property damage. Therefore, developing an efficient and realistic intrusion detection system (IdS) is critical for ensuring IoT network security. In recent years, traditional machine learning techniques have struggled to learn the complex associations between multidimensional features in network traffic, and the excellent performance of deep learning techniques, as an advanced version of machine learning, has led to their widespread application in intrusion detection. In this paper, we propose an Adaptive Particle Swarm Optimization Convolutional Neural Network Squeeze-and-Excitation (APSO-CNN-SE) model for implementing IoT network intrusion detection. A 2d CNN backbone is initially constructed to extract spatial features from network traffic. Subsequently, a squeeze-and-excitation channel attention mechanism is introduced and embedded into the CNN to focus on critical feature channels. Lastly, the weights and biases in the CNN-SE are extracted to initialize the population individuals of the APSO. As the number of iterations increases, the population’s position vector is continuously updated, and the cross-entropy loss function value is minimized to produce the ideal network architecture. We evaluated the models experimentally using binary and multiclassification on the UNSW-NB15 and NSL-Kdd datasets, comparing and analyzing the evaluation metrics derived from each model. Compared to the base CNN model, the results demonstrate that APSO-CNN-SE enhances the binary classification detection accuracy by 1.84% and 3.53% and the multiclassification detection accuracy by 1.56% and 2.73% on the two datasets, respectively. Additionally, the model outperforms the

关键词： adaptive particle swarm optimization channel attention mechanism convolutional neural network internet of things Intrusion detection system

Malargüe Site Remediation:A Successful Solution for Uranium Mill Tailings

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原子能科学技术 2024年第10期58卷 2088-2094页

作者： BARARI E díAZ J G GIOMIA KEMPF R A National Atomic Energy Commission Av.Del Libertador 8250Ciudad Autónoma de Buenos AiresC1429BNPArgentina

Comisión Nacional de Energía Atómica (CNEA) has the responsibility for restoring uranium mining facilities once the operations have ***,within its Environmental Program and in compliance with its legal responsibilities,decides to implement a restoration project for all sites related to the mining and processing of uranium *** Malargüe Site is located within the Province of Mendoza in the city of Malargü*** is the first site to successfully complete its *** activities consist of relocation of tailings to an engineering *** tailings management(encapsulation) and rehabilitation of the area was finished in June *** remediation alternative for the ore tailings was selected after conducting comparative studies and submitted the project to the society for *** objective of the encapsulation of the mineral tails is to isolate them from the environment,also proceeding with the decontamination and rehabilitation of the area (landscaping,post-closure monitoring and 20 years monitoring period).Encapsulation consisted of the construction of a containment cell for the mine tailings,to isolate them and prevent pollutants from entering the environment through the transfer *** clean the impacted areas,the soil was removed,it was incorporated into the encapsulation,and the filling was carried out with natural soils from the *** prevents radon transfer to the environment,as ^(222)Ra is an alpha emitter with a half-life of four days,which produces its own radioactive *** progeny are solids,and when a ^(222)Ra nucleus emits an alpha particle into the air,the resulting ^(218)Po nucleus,momentarily electrically charged,adheres to any dust *** prevents the discharge into the air containing radon and also containing dust particles charged with intensely radioactive radon *** tasks mentioned make it possible to decrease radon emanation,reduce radiological risks to the public and pre

关键词： remediation radionuclide transfer tailings encapsulation solution sustainable

Reference gene panel for urinary exosome-based molecular diagnostics in patients with kidney disease

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World Journal of Nephrology 2024年第3期13卷 62-72页

作者： deendayal d Mishra Pramod K Maurya Swasti Tiwari department of Molecular Medicine and Biotechnology Sanjay Gandhi Postgraduate Institute of Medical SciencesLucknow 226014Uttar PradeshIndia

BACKGROUNd Kidney disease is a severe complication of diabetes that often leads to end-stage renal *** diagnosis is crucial for prevention or ***,the current diagnostic methods,with their limitations in detecting the disease in its early stages,underscore the urgency and importance of finding new *** encapsulated inside urinary exosomes(UEs)have potential as early biomarkers for kidney *** need for reference miRNAs for accurate interpretation currently limits their translational *** To identify consistently expressing reference miRNAs from UEs of controls and patients with type 2 diabetesmellitus(T2dM)and biopsy-confirmed kidney *** miRNA profiling was performed on UEs from 31 human urine samples using a rigorous and unbiased *** UEs were isolated from urine samples collected from healthy individuals(n=6),patients with T2dM(n=13),and T2dM patients who also had kidney diseases(including diabetic nephropathy,n=5;membranous nephropathy,n=5;and IgA nephropathy,n=2)through differential *** characterizing the UEs,miRNA expression profiling using microarray technology was *** Microarray data analysis identified 14 miRNAs that were consistently expressed in UEs from 31 human samples,representing various kidney conditions:diabetic controls,diabetic nephropathy,membrane nephropathy,IgA nephropathy,and healthy *** in silico analysis,we determined that 10 of these miRNAs had significant potential to serve as reference genes in *** We identified uniformly expressing UE miRNAs that could serve as reference genes kidney disease biomarkers.

关键词： miRNA Microarray Urinary exosomes diabetic nephropathy Type 2 diabetes mellitus Kidney disease

Understanding the spectrum of non-motor symptoms in multiple sclerosis:insights from animal models

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Neural Regeneration Research 2024年第1期19卷 84-91页

作者： Poornima d.E.Weerasinghe-Mudiyanselage Joong-Sun Kim Taekyun Shin Changjong Moon department of Veterinary Anatomy and Animal Behavior College of Veterinary Medicine and BK21 FOUR programChonnam National UniversityGwangjuRepublic of Korea department of Veterinary Anatomy College of Veterinary Medicine and Veterinary Medical Research InstituteJeju National UniversityJejuRepublic of Korea

Multiple sclerosis is a chronic autoimmune disease of the central nervous system and is generally considered to be a non-traumatic,physically debilitating neurological *** addition to experiencing motor disability,patients with multiple sclerosis also experience a variety of nonmotor symptoms,including cognitive deficits,anxiety,depression,sensory impairments,and ***,the pathogenesis and treatment of such non-motor symptoms in multiple scle rosis are still under *** studies for multiple sclerosis benefit from the use of disease-appropriate animal models,including experimental autoimmune *** to understanding the pathophysiology and developing treatments for non-motor symptoms,it is critical to chara cterize the animal model in terms of its ability to replicate certain non-motor features of multiple *** such,no single animal model can mimic the entire spectrum of *** review focuses on the non-motor symptoms that have been investigated in animal models of multiple sclerosis as well as possible underlying ***,we highlighted gaps in the literature to explain the nonmotor aspects of multiple sclerosis in expe rimental animal models,which will serve as the basis for future studies.

关键词： anxiety cognitive deficit depression experimental autoimmune encephalomyelitis motor disability neurological disorder pain pathophysiology preclinical study sensory impairments

Anti-amyloid antibodies in Alzheimer’s disease: what did clinical trials teach us?

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Neural Regeneration Research 2025年第4期20卷 1092-1093页

作者： danko Jeremic Lydia Jiménez-díaz Juan d.Navarro-López NeuroPhysiology&Behavior Lab University of Castilla-La ManchaBiomedical Research Center(CRIB)School of Medicine of Ciudad RealCiudad RealSpain

Although many causes of Alzheimer’s disease(Ad)may exist,both the original amyloid cascade and tau hypotheses posit that abnormal misfolding and accumulation of amyloid-β(Aβ)and tau protein is the central event causing the ***,that conclusion could be only partly true,and there is conflicting evidence about the role of both proteins in Ad,being able to precede and influence one *** researchers argue that these proteins are mere executors rather than primary causes of ***,there have been continuing refinements of both hypotheses,with alternative explanations proposed.Aβand tau proteins may be independently involved in specific neurotoxic pathways;yet there may be other crucial processes going on in early ***,accumulating evidence suggests that Aβand tau act synergistically,rather than additively in disease onset(Jeremic et al.,2021,2023a).

关键词： amyloid Alzheimer additive

Geometric properties of the first singlet S-wave excited state of two-electron atoms near the critical nuclear charge

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Chinese Physics B 2024年第10期33卷 213-219页

作者： Tong Chen Sanjiang Yang Wanping Zhou Xuesong Mei d Haoxue Qiao School of Physics and Technology Wuhan UniversityWuhan 430072China College of Physics and Electronic Science Hubei Normal UniversityHuangshi 435002China School of Physics and Telecommunications Huanggang Normal UniversityHuanggang 438000China Wuhan Maritime Communication Research Institute Wuhan 430072China

The geometric structure parameters and radial density distribution of 1s2s1S excited state of the two-electron atomic system near the critical nuclear charge Z_(c)were calculated in detail under tripled Hylleraas basis *** to the localized behavior observed in the ground and the doubly excited 2p^(23)Pe states,for this state our results identify that while the behavior of the inner electron increasingly resembles that of a hydrogen-like atomic system,the outer electron in the excited state exhibits diffused hydrogen-like character and becomes perpendicular to the inner electron as nuclear charge Z approaches Z_(c).This study provides insights into the electronic structure and stability of the two-electron system in the vicinity of the critical nuclear charge.

关键词： critical nuclear charge two-electron atomic system geometric structure density distribution

Competitive interactions and coexistence of sympatric flagship carnivores in Asia

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Integrative Zoology 2024年第2期19卷 183-199页

作者： Zhilin LI Jiayu LU Xiaoyi SHI Li’an dUO James L.d.SMITH Tianming WANG Tianjin Key Laboratory of Conservation and Utilization of Animal diversity College of Life SciencesTianjin Normal UniversityTianjinChina department of Fisheries Wildlife and Conservation BiologyUniversity of MinnesotaSt.PaulMinnesotaUSA Ministry of Education Key Laboratory for Biodiversity Science and Engineering College of Life SciencesBeijing Normal UniversityBeijingChina National Forestry and Grassland Administration Key Laboratory for Conservation Ecology of Northeast Tiger and Leopard BeijingChina

Understanding the competition and coexistence of flagship carnivores is key to creating strategies for their conservation in the face of global carnivore *** studies exploring the dynamics and competition between tigers(Panthera tigris)and leopards(***)span decades,there is a lack of understanding regarding the factors that influence their coexistence mechanisms on a broad scale,as well as the drivers determining their exploitative and interference *** gathered a comprehensive list of research papers among which 36 papers explored the interspecific interactions between tigers and leopards and tested the influence of biotic and abiotic factors on the coexistence mechanisms along three dimensions using multiple response variables regression models;we also tested the influence of ecological drivers determining the exploitative or interference competition between tigers and *** and ungulate density were the most important predictors in regulating the coexistence *** and leopards exhibited more positive relations/higher overlaps as elevation increased in the spatial *** addition,they showed a higher dietary overlap in the prey-rich *** determined that interference competition between tigers and leopards was less frequently observed in habitats with dense tree cover and homogeneous vegetation ***,studies with multiple metrics would promote the detection of interference *** study provides new insight into the competitive interactions and coexistence mechanisms of tigers and leopards on a broad ***-makers and managers should pay more attention to the factors of elevation,prey abundance,and habitat structures for the conservation of tigers and leopards.

关键词： carnivores coexistence mechanisms competitive interactions exploitative competition interference competition

Chemical-assisted MMP reduction on methane-oil systems:Implications for natural gas injection to enhanced oil recovery

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Petroleum 2024年第1期10卷 101-108页

作者： Mohamed Almobarak Matthew B.Myers Colin d.Wood Yongbing Liu Ali Saeedi Quan Xie discipline of Petroleum Engineering WA School of Mines:MineralsEnergy and Chemical EngineeringCurtin UniversityWestern AustraliaAustralia Commonwealth Scientific and Industrial Research Organization Kensington6151Australia Curtin University Oil and Gas Innovation Centre Management Kensington6151Australia State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation No.8 Xindu AvenueXindu DistrictChengdu 610500PR China

***,the main challenge in this process is the high minimum miscibility pressure(MMP)between natural gas and crude oil,which limits its application and recovery factor,especially in hightemperature ***,we present a novel investigation to quantify the effect of chemicalassisted MMP reduction on the oil recovery ***,we measured the interfacial tension(IFT)of the methane-oil system in the presence of chemical or CO_(2) to calculate the MMP reduction at a constant temperature(373K)using the vanishing interfacial tension(VIT)***,we performed three coreflooding experiments to quantify the effect of MMP reduction on the oil recovery factor under different injection *** interfacial tension measurements show that adding a small fraction(1.5 wt%)of the tested surfactant(SOLOTERRA ME-6)achieved 9%of MMP reduction,while adding 20 wt%of CO_(2) to the methane yields 13%of MMP ***,the coreflooding results highlight the significance of achieving miscibility during gas injection,as the ultimate recovery factor increased from 65.5%under immiscible conditions to 77.2%using chemical-assisted methane,and to 79%using gas mixture after achieving near miscible *** results demonstrate the promising potential of the MMP reduction to signifi-cantly increase the oil recovery factor during gas ***,these results will likely expand the application envelop of the miscible gas injection,in addition to the environmental benefits of utilizing the produced gas by re-injection/recycling instead of flaring which contributes to reducing the greenhouse gas emissions.

关键词： Gas injection Enhanced oil recovery Miscibility Coreflooding

Coffee Leaf Rust(Hemileia vastatrix)disease in Coffee Plants and Perspectives by the disease Control

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Phyton-International Journal of Experimental Botany 2024年第5期93卷 923-949页

作者： Alexis Salazar-Navarro Victor Ruiz-Valdiviezo Jose Joya-dávila daniel Gonzalez-Mendoza Instituto de Ciencias Agrícolas de la Universidad Autónoma de Baja California(ICA-UABC) Nuevo LeónBaja California21705México Laboratorio de Biología Molecular del Instituto Tecnológico Nacional de Tuxtla Gutierrez(TecNM) Tuxtla GutierrezChiapas29050México Facultad de Ciencias Agronómicas Campus V.Universidad Autónoma de Chiapas(UNACH) VillafloresChiapas30470México

Coffee Leaf Rust(CLR)is caused by Hemileia vastatrix in Coffea *** is one of the most dangerous phytopathogens for coffee plantations in terms of coffee productivity and coffee cup *** this review,we resume the problem of CLR in Mexico and the pathogenesis of *** review abord plant-pathogen interactions which lead a compatible or incompatible interactions and result in CLR disease or resistance,*** review abord Coffea *** response pathways involved in *** ***,current measures to control *** proliferation and germination were aborded focused on phytosanitary actions,and biological and chemical ***,new trendlines to reduce the impact of CLR as nanoparticles and nanotechnology were analyzed.

关键词： Coffee leaf rust Coffea arabica pathogenesis nanoparticles biological control