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International Journal of digital Earth 2011年第S01期4卷 8-24页

作者： C.Corbane d.carrion M.Broglia European Commission Joint Research CentreIspraItaly

Validation is an emerging topic in the field of geospatial information for emergency *** the framework of the Global Monitoring for Environment and Security initiative,the Services and Applications for Emergency Response project seeks to implement and validate the pre-operational version of Emergency Response Core *** that context,a dedicated effort has been made in the development and implementation of a comprehensive,productoriented validation protocol tailored to crisis maps and data *** paper presents the approach for validation of crisis maps and its application in the context of rapid mapping of forest fires in Corsica during the summer of *** also discusses the main challenges and the critical aspects of validation of geospatial information in emergency response services.

关键词： validation protocol crisis mapping remote sensing forest fires

First extensive and cost-effective quality check of Crisis Maps: presentation of assessment parameters and results

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International Journal of digital Earth 2013年第S02期6卷 50-66页

作者： d.carrion C.Corbane M.Broglia M.Pesaresi Politecnico di Milano DIIARSurveyingMilanoItaly European Commission Joint Research CentreInstitute for the Protection and Security of the CitizenIspra(VA)Italy

The digital representation of disaster situations into maps,mainly based on remotely sensed observations,is becoming a widely used instrument for emergency *** of maps are being produced all over the world and big attention is paid by international institutions,such as the World Bank,the United Nations and the European Commission to these *** quality of crisis maps is a crucial element to ensure effectiveness in the disaster response chain,but it is often neglected with respect to the need for a rapid *** this paper a sample of crisis maps produced between 2005 and 2010 by world leader providers has been evaluated through around 40 parameters assessed by visual analysis and extracted from the validation protocol designed at the Joint Research Centre(JRC)of the European *** maps turned out to be in most cases clearly readable,but some gaps and inconsistencies have been singled out,due to the lack of international standard *** results are analysed in detail and some remarks are presented.

关键词： emergency maps quality assessment readability metadata cartographic standards

Validation of EO-derived information for crisis management: a digital Earth perspective in the VALgEO expert community

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International Journal of digital Earth 2011年第S1期4卷 1-7页

作者： Corbane, C. Pesaresi, M. carrion, d. European Commission Joint Research Centre Italy

New generation remote sensing technologies today open new application areas and demonstrate their effectiveness providing geo-information in support of disaster *** the same time,new challenges can be identified and among them the validation of geo-information under the new specific constraints dictated by the disaster management application area has a crucial *** the frame of the digital Earth concept,geo-information is a sharable resource,and a resource is truly shareable not only if we know the formal code used to make itand then we can read itbut alsoand in particular during disasterif we know the reliability of this *** is crucial in order to avoid information overflow and time wasting during the decision-making process in support of disaster ***‘International workshop on validation of geo-information products for crisis management,’VALgEO 2009,was held at the Joint Research Centre,in Ispra,Italy on 2123 November *** purpose of this first workshop was to initiate a dialog between the main actors of Emergency Response Services around validation and to raise awareness of the necessity for an independent formal assessment of geoinformation for disaster *** special issue includes a collection of invited papers presented at the *** gathers interdisciplinary initiatives where the majority of the contributions either directly or implicitly address different aspects of validation of geo-information generated following a disaster,ranging from flood information to forest fires and earthquake damage assessments.

关键词： disaster Earth flood

The IgH 3′ regulatory region super-enhancer does not control IgA class switch recombination in the B1 lineage

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Cellular & Molecular Immunology 2018年第3期15卷 289-291页

作者： Hussein Issaoui Nour Ghazzaui Alexis Saintamand Claire carrion Christelle Oblet Yves denizot CNRS UMR 7276 CRIBLUniversitéde LimogesLimogesFrance INSERM U1236 UniversitéRennes 1RennesFrance

The bone marrow-derived B2 population represents the vast majority of bone marrow,blood,lymph node and splenic *** B1 B-cells mostly originate during embryonic life in the liver and represent the main B-cell population in the pleural and peritoneal cavities.1,2,3,4,5 B1 and B2 B-cells differ in their origin,antigen specificity,cell surface markers,tissue distribution and capacity for class switch recombination(CSR).Schematically,B1 B-cells appear earlier than B2 B-cells during fetal development and maintain their self-renewal ability throughout their life.

关键词： maintain specificity mostly

Three-dimensional mapping and comparative analysis of the distal human corpus cavernosum and the inflatable penile prosthesis

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Asian Journal of Andrology 2013年第4期15卷 567-570,I0012页

作者： Tariq S Hakky daniel Ferguson Philippe E Spiess Paul Bradley Tom FLue Rafael E carrion department of Urology University of South Florida Tampa General Circle Tampa FL 33602 USA 23d3Solutions Burnaby BCV5J 5M8 Canada and department of Urology University of Southern California San Francisco 400 Parnassus Ave San Francisco CA 94143 USA

The intricate anatomy of the corpus cavernosum in both the flaccid and tumescent state has not been fully elucidated. We report our experience using a three-dimensional （3d） scanner to reconstruct cadaveric casts and compare them with 3d images of two prototypes of penile prosthesis. Two different models of the Titan Coloplast inflatable penile prosthesis were analyzed using a 3d scanner. The first was the standard model and the second was a newer model with a rounder silicone tip. Two cadaveric phalluses were harvested using Smooth-Cast 300Q polyurethane molding. The molds were excised and scanned along side the penile prosthesis. 3d scans were completed and analyzed using Leios Mesh software, and GOM Inspect software. The 3d scans demonstrated the mean human corporal radii 2 mm from the distal tip to be 36.51 mm （36.01-37.0 mm）, which is an obtuse angle. The standard Titan penile prosthesis spherical radius at the same level was 202.52 mm, while the new silicone tip prosthesis had a radius of 139.33 mm. 3d mapping further demonstrated the trajectory of the cavernosa appeared curvilinear and the distal ends appeared blunt. The use of cadaveric cavernosal molds in combination with the 3d scanner allowed us to accurately image the corpus cavernosum for the first time. Our findings suggest that anatomically accurate corporal tips appear to be relatively blunt and that the new Titan silicone tip penile prosthesis more closely resembles the human corporal tip.

关键词： corpus cavernosum penile prosthesis three-dimensional analysis

A dual function for the chromatin organizer Special A-T rich Binding Protein 1 in B-lineage cells

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Cellular & Molecular Immunology 2023年第10期20卷 1114-1126页

作者： Morgane Thomas Charlotte Bruzeau Ophélie Alyssa Martin Justine Pollet Sébastien Bender Claire carrion Sandrine Le Noir Eric Pinaud Laboratoire Contrôle de la Réponse Immune B et des Lymphoproliférations(CRIBL) Universitéde LimogesCNRS UnitéMixte de Recherche 7276Inserm Unité1262LimogesFrance Centre Hospitalier Universitaire dupuytren Service d’ImmunopathologieLimogesFrance Centre Hospitalier Universitaire de Limoges Centre National de l’Amylose AL et Autres Maladies par Dépôt d’Immunoglobulines MonoclonalesLimogesFrance Laboratoire Suivi des Therapies Innovantes Institut de Genetique HumaineUMR 9002 CNRS-UMMontpellierFrance

SATB1(Special A-T rich Binding protein 1)is a cell type-specific factor that regulates the genetic network in developing T cells and *** T cells,SATB1 is required for lineage commitment,VdJ recombination,development and *** that its expression varies during B-cell differentiation,the involvement of SATB1 needs to be clarified in this *** a KO mouse model in which SATB1 was deleted from the pro-B-cell stage,we examined the consequences of SATB1 deletion in naive and activated B-cell *** model indicates first,unlike its essential function in T cells,that SATB1 is dispensable for B-cell development and the establishment of a broad IgH ***,we show that SATB1 exhibits an ambivalent function in mature B cells,acting sequentially as a positive and negative regulator of Ig gene transcription in naive and activated cells,***,our study indicates that the negative regulatory function of SATB1 in B cells extends to the germinal center response,in which this factor limits somatic hypermutation of Ig genes.

关键词： B cells Nuclear factor Ambivalent Somatic hypermutation

Hepatitis B surface antigen and hepatitis B core-related antigen kinetics after adding pegylated-interferon to nucleos(t)ids analogues in hepatitis B e antigen-negative patients

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World Journal of Hepatology 2020年第11期12卷 1076-1088页

作者： Teresa Broquetas Montserrat Garcia-Retortillo Miquel Mico Lidia Canillas Marc Puigvehi Nuria Canete Susana Coll Ana Viu Juan Jose Hernandez Xavier Bessa JoseA carrion department of Gastroenterology Liver SectionHospital del Mar Medical Research InstituteBarcelona 08003Spain departament of de Medicina Universitat Autònoma de BarcelonaBarcelona 08003Spain Laboratori de Referencia de Catalunya El Prat de LlobregatBarcelona 08820Spain

BACKGROUNd Hepatitis B e antigen-negative chronic hepatitis B patients under nucleos(t)ids analogues(NAs)rarely achieve hepatitis B surface antigen(HBsAg)*** To evaluate if the addition of pegylated interferon(Peg-IFN)could decrease HBsAg and hepatitis B core-related antigen(HBcrAg)levels and increase HBsAg loss rate in patients under NAs *** Prospective,non-randomized,open-label trial evaluating the combination of Peg-IFN 180μg/week plus NAs during forty-eight weeks vs NAs in *** B e antigen-negative non-cirrhotic chronic hepatitis B patients of a tertiary hospital,under NAs therapy for at least 2 years and with undetectable viral load,were *** with hepatitis C virus,hepatitis d virus or human immunodeficiency virus co-infection and liver transplanted patients were *** and HBcrAg levels(log10 U/mL)were measured at baseline and during ninety-six *** loss rate was evaluated in both *** events were recorded in both *** kinetic of HBsAg for each treatment group was evaluated from baseline to weeks 24 and 48 by the slope of the HBsAg decline(log10 IU/mL/week)using a linear regression *** Sixty-five patients were enrolled,61%receiving tenofovir and 33%***-six(55%)were included in Peg-IFN-NA group and 29(44%)in NA *** matching by age and treatment duration,baseline HBsAg levels were comparable between groups(3.1 vs 3.2)(P=0.25).HBsAg levels at weeks 24,48 and 96 declined in Peg-IFN-NA group(-0.26,-0.40 and-0.44)and remained stable in NA group(-0.10,-0.10 and-0.10)(Pdecline in Peg-IFN-NA group(-0.02)was higher than in NA group(-0.00)(P=0.015).HBcrAg levels did not ***(22%)patients discontinued Peg-IFN due to adverse *** HBsAg loss was achieved in 3(8.3%)patients of the Peg-IFN-NA group and 0(0%)of the NA *** The addition of Peg-IFN to NAs caused a greater and faster decrease of HBsAg levels compared to N

关键词： Chronic hepatitis B Hepatitis B e antigen-negative Hepatitis B surface antigen Hepatitis B core-related antigen Pegylated-interferon Nucleos(t)ids analogues©The Author(s)2020.Published by Baishideng Publishing Group Inc.All rights reserved

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地震反射数据的全波动方程向下延拓

油气藏评价与开发 1987年第5期 14-20页

作者： d.J.Foster Ph.M.carrion 纪少游

本文提出一种压制地震记录中多次反射的新方法。它是建立在应用全声波方程(双曲线形式)作为向下延拓算子的向下延拓方法基础上的。我们证明记录波场的向下延拓可绘成反射率函数曲线,而没有多次反射波。该方法成功地应用于单道平面波以分... 详细信息

本文提出一种压制地震记录中多次反射的新方法。它是建立在应用全声波方程(双曲线形式)作为向下延拓算子的向下延拓方法基础上的。我们证明记录波场的向下延拓可绘成反射率函数曲线,而没有多次反射波。该方法成功地应用于单道平面波以分解(倾斜叠加)合成记录和野外数据。

关键词：向下延拓野外数据倾斜叠加全波动方程波场震源子波偏移速度上行波地震波射线参数射线理论多次波多次反射波地震记录合成记录

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应用亚临界反射、折射资料做地震反演

油气藏评价与开发 1986年第6期 56-62页

作者： P. M. carrion d. J. Foster 朱海

我们提出了一种两步反演程序以便从大偏移地震资料中选取地下速度估算。第一步是自动迭代大偏移反演方法(ALLOIM),在海底有强多次波出现时,我们用这种方法做过试验。因为该方法是依赖于找到临界反射点的位置,所以就无法分辨低速带,而重... 详细信息

我们提出了一种两步反演程序以便从大偏移地震资料中选取地下速度估算。第一步是自动迭代大偏移反演方法(ALLOIM),在海底有强多次波出现时,我们用这种方法做过试验。因为该方法是依赖于找到临界反射点的位置,所以就无法分辨低速带,而重新构成的仅仅是速度的平均估算。在存在低速带时就需要进行反演过程的第二步。这第二步就是用于亚临界反射的广义最小平方法。我们应用扰动技术来计算反演解,并从第一步确定的平均速度估算来确定参数模型。这种反演方法的两个主要特性是:将反射波至的振幅合并在一起进行分析,而且能得到没有人为干扰的(拾取走时曲线)精确结果。应用合成和野外资料的数值实例证明了我们反演程序的精确性。

关键词：倾斜叠加截距时间反射波迭代映象反射系数法低速带多次波多次反射波反演方法射线参数射线理论临界反射地震反演速度估算

Foraging behavior related to habitat characteristics in the invasive wasp Vespula germanica

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Insect Science 2007年第5期14卷 383-388页

作者： PAOLA d'AdAMO MARIANA LOZAdA Laboratorio Ecotono Universidad Nacional del Comahue Bariloche Argentina

When foraging on carrion resources, the wasp Vespula germanica usually makes repeated visits to the feeding site until depleting the resource. In the present study we analyzed how environmental cues affect wasps＇ behavior when re-locating a protein food source. We studied this behavior in two different natural habitats： closed and open habitats. As closed habitats have more references to orient wasps to the feeding site than open habitats, we hypothesized that they would return to the foraging site more frequently in closed habitats than in open ones. We tested this hypothesis by studying wasp behavior in three different natural habitat conditions：（i） closed habitats, （ii） open habitats, and （iii） open habitats artificially modified by adding five sticks with flagging. Experiments consisted of training individual wasps to feed from a certain array, and at the testing phase we removed food and displaced the array by 60 cm. Therefore, we recorded wasps＇ choices when returning to the training area, by counting both the wasps＇ first approaches and the number of visits to the original feeding site and the displaced array. Wasps＇ behavior while re-locating a protein food source was different if foraging at open or closed habitats. Wasps more frequently re- visited a previous feeding location when foraging in closed habitats than when foraging in open ones. Furthermore, wasps more frequently visited the displaced array than the original feeding site in all three treatments. Nevertheless, when wasps were trained in closed habitats, they returned to the original feeding site more frequently than if trained in open ones. Interestingly, when five sticks with flagging were added in open habitats, wasps responded similarly as in closed habitats without these references. The results show that foraging behavior in V. germanica seems to be different in closed and open habitats, probably associated with the existence of references that guide foragers when re-locating undepleted res

关键词： environmental cues food exploitation invasive species re-localization socialwasps Vespidae