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consortium chain consensus Vulnerability and chain Generation Mechanism

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computers, Materials & continua 2023年第11期77卷 2505-2527页

作者： Rui Qiao hi dong School of computer Science and Technology Zhoukou Normal UniversityZhoukou466001China

Effectively identifying and preventing the threat of Byzantine nodes to the security of distributed systems is a challenge in applying consortium ***,this paper proposes a new consortium chain generation model,deeply analyzes the vulnerability of the consortium chain consensus based on the behavior of the nodes,and points out the effects of Byzantine node proportion and node state verification on the consensus process and system ***,the normalized verification node aggregation index that represents the consensus ability of the consortium organization and the trust evaluation function of the verification node set is *** either of the two is lower than the threshold,the consortium institution or the verification node set members are dynamically *** this basis,an innovative consortium chain generation mechanism based on the Asynchronous Binary Byzantine consensus Mechanism(ABBcM)is *** on the extended consortium chain consensus mechanism,a certain consensus value set can be combined into multiple proposals,which can realize crossdomain asynchronous message passing between multi-consortium chains without reducing the system’s *** addition,experiments are carried out under four classical Byzantine Attack(BA)behaviors,BA1 to *** results show that the proposed method can obtain better delay than the classical random Byzantine consensus algorithm coin,effectively improving the consensus efficiency based on asynchronous message passing in the consortium chain and thus meeting the throughput of most Internet of Things(IoT)applications.

关键词： consortium chain Byzantine consensus generation mechanism Internet of Things consensus vulnerability

Praziquantel efficacy against Schistosoma mansoni among hiV-1 infected and uninfected adults living in fishing villages along Lake Victoria, Northwest Tanzania

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Infectious diseases of Poverty 2014年第1期3卷 440-448,439页

作者： Humphrey d Mazigo david W dunne Safari M Kinung’hi Fred Nuwaha department of Medical Parasitology and Entomology School of MedicineCatholic University of Health and Allied SciencesP.O.Box 1464MwanzaTanzania department of disease control and Environmental Health School of Public HealthCollege of Health SciencesMakerere UniversityP.O.Box 7072KampalaUganda department of Pathology Division of Microbiology and ParasitologyCambridge UniversityTennis Court RoadCambridge CB21QPUK National Institute for Medical Research Mwanza Research CentreP.O.Box 1462 MwanzaTanzania

Background:Animal studies have demonstrated that functional immune responses,as determined by the levels of cd4+cell counts and anti-schistosome antibodies responses,determine the efficacy of *** on this evidence,it has been hypothesised that the immunodeficiency effects of the human immunodeficiency virus(hiV)-1 infection may affect the efficacy of praziquantel in co-infected human ***,the present study assessed the efficacy of praziquantel by comparing parasitological cure rates and the reduction in infection intensity in hiV-1 seronegative individuals infected with *** and hiV-1 seropositive individuals co-infected with ***,following treatment with a single oral dose of ***:This was a prospective longitudinal study which included,at baseline,555 *** infected adults aged 21-55 years,who were either co-infected or not with hiV-1 and who lived in fishing villages along Lake Victoria in Northwest *** individuals were treated with a single oral dose of praziquantel(40 mg/kg)and,at 12 weeks,single stool samples were obtained and examined for *** eggs using the Kato-Katz *** prick and venous blood samples were collected for hiV-1 screening and cd4+cell ***:The parasitological cure rate did not differ significantly from the hiV-1 serostatus(P=0.12):among the co-infected individuals,the cure rate was 48.3%(14/29),and among the individuals infected only with ***,the cure rate was 62.6%(329/526).The egg reduction rate did not vary with the hiV-1 serostatus(P=0.22):77.22%for hiV-1 seronegative and 75%for hiV-1 seropositive *** level of cd4^(+) cell counts(median 228 cells/μL:range 202-380 cells)did not influence the cure rate(P=0.23)or the reduction in the intensity of the infection(P=0.37).conclusion:The hiV-1 infection per se or its moderate immunodeficiency effects,demonstrated by the range of cd4^(+) cell counts observed in co-infected individuals,d

关键词： hiV-1 S.mansoni co-infection Praziquantel Efficacy Tanzania

Tracking people through partial occlusions

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The Journal of china Universities of Posts and Telecommunications 2009年第2期16卷 117-121页

作者： LU Jian-guo cAI An-hi School of Information and communication Engineering Beijing University of Posts and Telecommunications Beijing 100876 China

This article presents a novel people-tracking approach to cope with partial occlusions caused by scene objects. Instead of predicting when and where the occlusions will occur, a part-based model is used to model the pixel distribution of the target body under occlusion. The subdivided patches corresponding to a template image will be tracked independently using Markov chain Monte carlo （McMc） method. A set of voting-based rules is established for the patch-tracking result to verify if the target is indeed located at the estimated position. Experiments show the effectiveness of the proposed method.

关键词： partial occlusion part-based model McMc voting-based rules

Rb-Sr isotope dating of silicalite from the dajiangping massive sulfide ore deposit,Guangdong Province

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chinese Science Bulletin 1997年第23期42卷 1983-1985页

作者： Wang, hi Li, HY Wang, YX Wang, HH Nanjing Univ Dept Earth Sci Nanjing 210093 Peoples R China

THE dajiangping pyrite ore deposit located in the Yunfu county of Guangdong Province is asuper-large pyrite ore deposit. Its age has not been defined so far because of the absence of fos-sil. This note is to use Rb-Sr isotope dating of silicalite to constrain the age of the ore depositand place special emphasis on its geological significance.

关键词： pyrite ore deposit silicalite Rb-Sr isotope ore-forming age.

The structure, expression, and multifaceted role of immune-checkpoint protein VISTA as a critical regulator of anti-tumor immunity, autoimmunity, and inflammation

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cellular & Molecular Immunology 2018年第5期15卷 438-446页

作者： Wenwen Xu TạMinh hiếu Subramaniam Malarkannan Li Wang department of Microbiology and Immunology MilwaukeeWI 53226USA department of Medicine MilwaukeeWI 53226USA department of Pediatrics Medical College of WisconsinMilwaukeeWI 53226USA Blood Research Institute MilwaukeeWI 53226USA

Among various immunoregulatory molecules,the B7 family of immune-checkpoint receptors consists of highly valuable targets for cancer *** targeting two B7 family co-inhibitory receptors,cTLA-4 and Pd-1,have elicited long-term clinical outcomes in previously refractory cancer types and are considered a breakthrough in cancer *** the success,the relatively low response rate(20–30%)warrants efforts to identify and overcome additional immune-suppressive *** the expanding list of T cell inhibitory regulators,V domain immunoglobulin suppressor of T cell activation(VISTA)is a unique B7 family checkpoint that regulates a broad spectrum of immune ***,we summarize recent advances that highlight the structure,expression,and multi-faceted immunomodulatory mechanisms of VISTA in the context of autoimmunity,inflammation,and anti-tumor immunity.

关键词： cancer immunotherapy immune checkpoint autoimmunity inflammation tumor immunity

NEUROcOMPUTING THEORY ANd NUMERIcAL SIMULATION ON ELASTIcITY

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Acta Mechanica Solida Sinica 1999年第3期12卷 269-278页

作者： Sun, dH Sun, XF hi, Q Xu, H Xiamen Univ Dept Electromech Engn Xiamen 361005 Peoples R China Sw Jiaotong Univ Dept Appl Mech & Engn Chengdu 610031 Peoples R China NE Univ Technol Inst Engn Mech Shenyang 110006 Peoples R China

A new finite element analysis principle based on neural networks is proposed. It can realize the finite element analysis in real time. The neural computation of a simple structure was simulated on digital computer, the effect of input parameters on convergent speed and precision was analyzed. Before solving a certain FE problem, the linking weight matrix of the neural net, i.e., the global stiffness matrix of the structure analyzed, must be defined. In this paper, a method which uses the BP net to compute the element stiffness matrix in real time is proposed.

关键词： neural networks elasticity finite element real-time computation

Field and reverse field solitons in waveoperator nonlinear Schrödinger equation with space-time reverse: Modulation instability

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communications in Theoretical Physics 2023年第6期75卷 39-50页

作者： H I Abdel-Gawad Mathematics department Faculty of Science cairo University GizaEgypt

The wave-operator nonlinear Schrödinger equation was introduced in the ***,nonlocal space-time reverse complex field equations were also recently *** in this area were focused on employing the inverse scattering method and darboux ***,we present an approach to find the solutions of the wave-operator nonlinear Schrödinger equation with space and time reverse(W-O-NLSE-STR).It is based on implementing the unified method together with introducing a conventional formulation of the ***,a field and a reverse field may be ***,for deriving the solutions of W-O-NLSE-STR,it is evident to distinguish two cases(when the field and its reverse are interactive or not-interactive).In the non-interactive and interactive cases,exact and approximate solutions are *** both cases,the solutions are evaluated numerically and they are displayed *** is observed that the field exhibits solitons propagating essentially(or mainly)on the negative space variable,while those of the reverse field propagate on the other side(or vice versa).These results are completely novel,and we think that it is an essential behavior that characterizes a complex field system with *** the other hand,they may exhibit right and left cable patterns(or vice versa).It is found that the solutions of the field and its reverse exhibit self-phase modulation by solitary *** the interactive case,the pulses of the field and its reverse propagate in the whole *** analysis of modulation stability shows that,when the field is stable,its reverse is unstable or both are *** holds whenever the polarization of the medium is selfdefocusing.

关键词： wave-operator nonlinear Schrödinger equation space-time reverse unified method

Ipsilateral hemifacial microsomia with dextrocardia and pulmonary hypoplasia:A case report

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World Journal of clinical cases 2022年第9期10卷 2948-2953页

作者： Rui Guo Shi-hi chang Bing-Qing Wang Qing-Guo Zhang department of Ear Reconstruction Plastic Surgery HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100000China

BAcKGROUNd Hemifacial microsomia(HFM)is a rare congenital malformation characterized by a combination of various anomalies,including the face,ears,eyes,and *** diagnosis for HFM is possible,and quite accurate ultrasound can detect obvious *** etiology is still unknown,although some hypotheses have been proposed,including gene mutation,chromosome anomaly,and environmental risk ***,there are few reports of pulmonary hypoplasia and dextrocardia in *** SUMMARY A 2-year-old boy presented to the ear reconstruction department of our hospital complaining of deviation of the face to the right side and auricular *** examination revealed facial asymmetry,preauricular skin tags,and concha-type microtia with stricture of the external auditory canal on the right *** magnetic resonance imaging showed bilateral semicircular canal dysplasia and bilateral internal auditory canals *** examination showed bilateral severe sensorineural hearing *** radiography and computed tomography showed dextrocardia and right pulmonary *** This case presented a rare finding and an unusual association of 3 malformations,ipsilateral HFM,pulmonary agenesis,and dextrocardia.

关键词： Hemifacial microsomia Oculoauriculovertebral spectrum dextrocardia Pulmonary hypoplasia congenital anomaly case report

Statistics of oxidation resistance of Ni-(0-15)co-(8-15)cr-(0-5)Mo-(0-10)W-(3-8)Al-(0-5)Ti-(0-10)Ta-0.1c-0.01B superalloys at 1000℃ by compositional variations

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Rare Metals 2020年第8期39卷 918-927页

作者： Si-Jun Park Kyu-Hyuk Lee Seong-Moon Seo hi-Won Jeong Young-Soo Yoo HeeJin Jang Multi-Material Research center Gwangju-Jeonnam DivisionKorea Automotive Technology InstituteGwangju 62207Republic of Korea department of Advanced Materials Engineering Chosun UniversityGwangju 61452Republic of Korea high Temperature Materials Group Korea Institute of Materials ScienceChangwon 51508Republic of Korea department of Materials Science and Engineering Chosun UniversityGwangju 61452Republic of Korea

The effects of alloying elements(co,cr,Mo,W,Al,Ti,and Ta)on the oxidation resistance of Ni-(0-15)co-(8-15)cr-(0-5)Mo-(0-10)W-(3-8)Al-(0-5)Ti-(0-10)Ta-0.1 c-0.01 B alloys were *** sample compositions were designed by the Box-Behnken method of design of experiments(dOE).The alloying elements show complicated effects on the mass gain due to oxidation,depending on the alloy *** reduces the mass gain *** other elements except Al do not appear to exert a strong effect on the oxidation rate on average,but their influences are shown clearly in the alloys with a low Al ***,W,and Ta reduce the oxidation rate,while cr,Mo,and Ti promote *** is the most effective element in reducing the oxidation rate of the alloy with a low Al *** is confirmed that a continuous Al2O3 layer is essentially required for high oxidation *** oxide scale of easily oxidized alloys has various oxides such as Nicr2O4,NiAl2O4,NiO,cr2O3,crTaO4,and TiO2.

关键词： high temperature oxidation Alloy composition Ni-based superalloy Oxidation resistance design of experiments