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稳定型心绞痛患者成功进行经皮冠状动脉介入后血清心肌标记物与其后运动耐量的关系：一项初步研究

世界核心医学期刊文摘（心脏病学分册） 2005年第8期1卷 26-27页

作者： Williams S.G. Stables R.H. Wright d.J. 王永兴 Cardiothoracic Centre Thomas Drive Liverpool L14 3PE United Kingdom

We performed a pilot study to assess the significance of modest, asymptomatic, elevated serum cardiac markers- troponin T(TnT) and creatinine kinase- MB(CK- MB)- 18- 24 h following successful elective percutaneous coronary intervention(PCI) and to explore their relationship with changes in aerobic exercise capacity, as measured by peak oxygen consumption(VO2), 6 weeks following the procedure. Twenty-three patients with single-vessel disease and chronic angina performed an incremental cardiopulmonary exercise test before and 6 weeks after successful uncomplicated PCI. A venous blood sample was taken at rest before PCI and 18-24 h after the procedure. Successful PCI resulted in a trend towards an increased peak VO2 [21. 62 ±0. 64(pre) vs. 23. 03±0. 75 ml/kg/min(post), p = 0. 07; mean ± SEM] . There was a significant increase [median(IQR) ] in TnT, from 0. 00(0. 00) μg/l at baseline increasing to 0.02(0.03) μg/l at 18-24 h, p = 0. 002. CK-MB levels showed no significant difference. In the group of 15/23(65%) patients with an elevation in serum TnT( ff>> 0. 01 μg/l), 18-24 h after successful PCI, there was no significant increase in peak VO2 [23. 31 ±0. 96(pre)vs. 23. 89 ± 1. 09 ml/kg/min(post), p=0. 57] . In 8(35% ) patients with no rise in TnT at 18 - 24 h, a significant increase in peak VO2 was observed following successful PCI[23. 10 ±0. 91 (pre) vs. 25. 09 ± 0. 75 ml/ kg/min(post), p =0. 02]. Although 7 of these 8 patients increased their peak VO2, the absence of a TnT rise at 18-24 h was not significantly associated with an increase in peak VO2 following successful PCI(p =0. 18). To confirm these interesting initial results and investigate the relationship of serum cardiac markers following successful PCI and subsequent exercise capacity, further studies are required.

关键词：稳定型心绞痛运动耐量血清心肌单支血管病变肌酸肌酶肌钙蛋白无症状介入治疗耗氧量

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通过观察放射性核素在肠道的运送情况来评估慢性特发性便秘患儿大肠运送功能阻滞的部位

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世界核心医学期刊文摘（儿科学分册） 2005年第8期1卷 39-40页

作者： Cook B.J. Lim E. Cook d. J.M. Hutson 宁亮 department of Pediatric Surgery Royal Children's Hospital Parkville Vic. 3052 Australia

Purpose: Chronic idiopathic constipation (CIC) with soiling in children may r esult from slow colonic transit (SCT) or anorectal dysfunction and/or psychologi cal problems known as functional fecal retention (ffR). Evidence is accumulating that SCT and ffR need different treatments, but they are poorly distinguished b y solid marker studies. The authors used radionuclear transit scintigraphy to ca tegorize children with CIC as having either ffR or SCT. Methods: Children (N = 1 01) with CIC (and soiling) who were referred for further investigation after failure of standard treatments (diet, laxatives) received radiolabeled colloid orally, and scintillation images were collected at 0 to 2, 6, 24, 30 and 48 hours (total radiation dosage = 2 st andard x- rays). Radioactivity in 6 regions (precolonic, ascending, transverse, descending, rectosigmoid, and evacuated feces) was measured, and the median pos ition (geometric center) of radioactivity at each time was determined. Results: In children, meals normally reach the cecum at 6 hours and are evacuated in 30 t o 58 hours. Fifty patients had retention of radioactivity in the proximal colon at 48 hours, indicating SCT. Analysis of the images and the geometric center sho wed that passage through the ascending colon and transverse colon was delayed in SCT. In 24 patients, radioactivity was passed by 30 hours, indicating normal tr ansit or possible ffR. Twenty- two patients had retention in the rectum, indica ting definite ffR. Five studies were borderline. Conclusions: Radionuclear trans it scintigraphy is useful for categorizing patients with CIC as having either ff R or SCT, allowing for different treatments. Radionuclear transit scintigraphy p rovides more detail and greater sensitivity than solid marker studies in diagnos ing CIC. Radionuclear transit scintigraphy showed that half of our patients had SCT.

关键词：放射性核素慢性特发性便秘放射强度直肠乙状结肠放射性标记放射剂量缓泻剂肛门直肠标准化治疗小儿则

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Enhancing MANET by Balanced and Energy Efficient Multipath Routing with Robust Transmission Mechanism with Using ff-AOMdV

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Communications and Network 2021年第4期

作者： Naif d. Alotaibi Elyas I. Assiri

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脊柱骨转移与良性红骨髓沉积的鉴别：脂肪抑制T2加权成像与脂肪分数图的作用

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国际医学放射学杂志 2022年第6期45卷 744-744页

作者： S.Park J.d.Huh 刘春明

摘要目的采用脂肪抑制（FS）T2加权成像（T2FS）和脂肪分数（ff）图得出的定量参数来鉴别脊柱骨转移瘤（BM）和良性红骨髓沉积（BRM）。方法根据 MRI 和骨扫描或 PET/CT

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Ten decadal advances in fungal biology leading towards human well‑being

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Fungal diversity 2022年第5期116卷 547-614页

作者： Ausana Mapook·Kevin dHyde Kevin d.Hyde Khadija Hassan Blondelle Matio Kemkuignou Adela Cmokova Frank Surup Eric Kuhnert Pathompong Paomephan Tian Cheng Sybren de Hoog Yinggai Song Ruvishika S.Jayawardena Abdullah M.S.Al‑Hatmi Tokameh Mahmoudi Nadia Ponts Lena Studt‑Reinhold Florence Richard‑Forget K.W.Thilini Chethana dulanjalee L.Harishchandra Peter E.Mortimer Huili Li Saisamorm Lumyong Worawoot Aiduang Jaturong Kumla Nakarin Suwannarach Chitrabhanu S.Bhunjun Feng‑Ming Yu Qi Zhao doug Schaefer Marc Stadler Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand department Microbial drugs Helmholtz Centre for Infection Research(HZI)and German Centre for Infection Research(DZIF)Partner Site Hannover‑BraunschweigInhoffenstrasse 738124 BrunswickGermany Institute of Microbiology Technische Universitat BraunschweigSpielmannstrase 738106 BrunswickGermany Laboratory of Fungal Genetics and Metabolism Institute of MicrobiologyCzech Academy of SciencesPragueCzech Republic Centre of Biomolecular drug Research(BMWZ) Institute for Organic ChemistryLeibniz University HannoverSchneiderberg 3830167 HannoverGermany department of Biotechnology Faculty of ScienceMahidol University272 Rama VI RoadRatchathewiBangkok 10400Thailand Center of Expertise in Mycology Radboud University Medical Center/Canisius Wilhelmina HospitalNijmegenThe Netherlands Key Laboratory of Environmental Pollution Monitoring and disease Control Guizhou Medical UniversityGuiyangChina Microbiology Parasitology and Pathology Graduate ProgramFederal University of ParanaCuritibaBrazil department of dermatology Peking University First HospitalPeking UniversityBeijingChina Natural and Medical Sciences Research Center University of NizwaNizwaOman department of Biochemistry Erasmus University Medical CenterRotterdamThe Netherlands INRAE UR1264 Mycology and Food Safety(MycSA)33882 Villenave d’OrnonFrance department of Applied Genetics and Cell Biology Institute of Microbial GeneticsUniversity of Natural Resources and Life SciencesVienna(BOKU)Tulln an der DonauAustria Beijing Key Laboratory of Environment Friendly Management on Fruit diseases and Pests in North China Institute of Plant ProtectionBeijing Academy of Agriculture and Forestry SciencesBeijing 100097China Key Laboratory for Plant diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunming 650201YunnanChina Centre for Mountai

Fungi are an understudied resource possessing huge potential for developing products that can greatly improve human *** the current paper,we highlight some important discoveries and developments in applied mycology and interdisciplinary Life Science *** examples concern recently introduced drugs for the treatment of infections and neurological diseases;application of–OMICS techniques and genetic tools in medical mycology and the regulation of mycotoxin production;as well as some highlights of mushroom cultivaton in *** for new diagnostic tools in medical mycology and the exploitation of new candidates for therapeutic drugs,are also *** addition,two entries illustrating the latest developments in the use of fungi for biodegradation and fungal biomaterial production are *** other areas where there have been and/or will be significant developments are also *** is our hope that this paper will help realise the importance of fungi as a potential industrial resource and see the next two decades bring forward many new fungal and fungus-derived products.

关键词： Biomaterial CRISPR drug development Morel cultivation Mushroom cultivation Mycotoxin biosynthesis Plastic degradation

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Improvement of power efficiency of polymer solar cell based on P3HT:PCBM blends

Improvement of power efficiency of polymer solar cell based ...

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2007亚洲光电子会议固态照明与太阳能技术分会场

作者： Li Weimina,b,Guo Jinchuan*c,Sun Xiuquand,Zhou Binc aCollege of Optoelectronic Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074,P R China bSchool of Mechatronics and Control Engineering ,Shenzhen University, Shenzhen 518060,P R China c Institute of optoelectronics Shenzhen University, Shenzhen 518060,P R China d School of Electronic Science and Technology ,Shenzhen University, Shenzhen 518060,P R China

The effect of interlayer on the performance of a poly[2-methoxy-5-（3’,7’-dimethylocty）-1,4-phenylenevinylene] （MdMO-PPV）/1-（3-methoxycarbony 1）-propy1-1 phney1-（6-6）C61 （PCBM） composite solar cell device has been reported recently. Herein we report bulk heterojunction organic solar cell with efficiency enhanced by interlayer made from blend film of regioregular poly（3-hexylthiophene）（P3HT） and PCBM. The interlayer, poly（9,9-dioctylfluorene）-co-N-（1,4-butylphenyl）diphenylamine)（TFB）,was inserted between the poly（3,4-ethylene dioxythiophene）-poly（styrene sulfonic acid）（PEdOT:PPS） and the active layer. With the interlayer, the efficiency was enhanced due to the increased short circuit current density （Jsc）,open circuit voltage （Voc） and fill factor （ff） obtained from testing and calculation. According to the analysis, the interlayer TFB, acting as an effective exciton-blocking layer, prevented the severe quenching of radiative excitons between the interface of PEdOT:PSS. In the study, the interlayer increased Jsc from 0.891 mA/cm2 to 1.025 mA/cm-2 ,Voc from 0.478 V to 0.526 V , and ff from 0.327 to 0.416, under illumination by white light from a solar simulator with an incident intensity of 80mW/cm2;the power conversion efficiency of the device reached higher value 0.280% comparing with 0.174%with no interlayer.

关键词： interlay TFB bulk heterojunction P3HT PCBM efficiency

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R2*与脂肪分数、骨密度的相关性及其在骨质疏松定量评价中的作用

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国际医学放射学杂志 2023年第6期 745-745页

作者： Z.H.Liu d.G.Huang Y.H.Jiang X.W.Ma Y.T.Zhang R.Chang 周新哲

摘要目的研究R2*与椎体脂肪分数(ff)、骨密度(BMd)的相关性，探讨其在骨质疏松(OP)定量评估中的作用。方法共纳入83例下腰痛病人[(59.77±7.46)岁，男30例]，在48 h

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接受呼吸系统结核病治疗儿童的异烟肼药物代谢动力学的改变

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世界核心医学期刊文摘（儿科学分册） 2005年第10期1卷 18-18页

作者： Schaaf H.S. Parkin d.P. Seifart H.I. 郭战宏 Paediatrics and Child Health Stellenbosch University PO Box 19063 7505 Tygerberg South Africa Dr.

Aims: To define the pharmacokinetics of isoniazid (INH) in children with tuber culosis in relation to the N-acetyltransferase 2 (NAT2) genotype. Methods: The first order elimination rate constant (k) and area under the concentration curve (AUC) were calculated in 64 children dian 3.8) with respir atory tuberculosis from INH concentrations determined 2-5 hours after a 10 mg/k g INH dose. The NAT2 genotype was determined; 25 children were classified as hom ozygous slow (SS), 24 as heterozygous fast (FS), and 15 as homozygous fast (ff) acetylators. Results: The mean (Sd) k values of the genotypes differed significa ntly from one another: SS 0.254 (0.046), FS 0.513 (0.074), ff 0.653 (0.117). Wit hin each genotype a median regression of k on age showed a significant decrease in k with age. The mean (Sd) INH concentrations (mg/l) two hours after INHadmini stration were SS 8.599 (1.974), FS 5.131 (1.864), and ff 3.938 (1.754). A within genotype regression of 2-hour INH concentrations on age showed a significant i ncrease with age. A within genotype regression of 3-hour, 4-hour, and 5-hour concentrations on age also showed a significant increase with age in each instan ce. In ethnically similar adults, mean (Sd) 2-hour INH concentrations (mg/l) fo r each genotype were significantly higher than the children’s: SS 10.942 (1.740 ), FS 8.702 (1.841), and ff 6.031 (1.431). Conclusions: Younger children elimina te INH faster than older children and, as a group, faster than adults, and requi re a higher mg/kg body weight INH dose to achieve serum concentrations comparabl e to adults.

关键词：呼吸系统结核病药物代谢动力学消除速率常数乙酰基转移酶纯合杂合

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体外受精周期中卵泡内雌二醇减少可降低卵巢对重组人卵泡刺激素的反应性

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世界核心医学期刊文摘（妇产科学分册） 2005年第9期1卷 12-12页

作者： Foong S.C. Abbott d.H. Lesnick T.G. 李跃萍 Mayo Clinic Sect. Repro. Endocrinol. Infertility 200 First Street SW Rochester MN 55905 Unite d States Dr.

Objective: To correlate serum and intrafollicular E2 levels in women receiving GnRH agonist and recombinant human (h)-FSH for IVF. design: Prospective study. Setting: Academic IVF center. Patient(s): Twenty-three nonhirsute ovulatory wo men. Intervention(s): In vitro fertilization cycles were classified as high-or low-normal response, according to whether the amount of recombinant hFSH admini stered was below or above, respectively, the mean recombinant hFSH given to all women combined. Serum bioactive LH and immunoreactive FSH were measured during p ituitary desensitization preceding recombinant hFSH and repeated at oocyte retri eval. The first mature follicle aspirated from either ovary had a mean diameter >15 mm. Main Outcome Measure(s): Serum and follicular fluid (ff) insulin, bioact ive LH, immunoreactive FSH, and steroid levels. Result(s): Basal serum gonadotro pin levels were comparable between female groups. Serum immunoreactive FSH level s, but not bioactive LH levels, at oocyte retrieval were greater in cycles of lo w-normal vs. high-normal response, whereas maximum serum E2 levels and total o ocyte counts were similar between both groups. despite elevated ff immunoreactiv e FSH levels, ff E2 was decreased in low-normal response cycles. Intrafollicula r T and P also were decreased and increased, respectively, in cycles of low-nor mal response, although ff bioactive LH levels were comparable in both groups. Co nclusion(s): Intrafollicular E2 is decreased in cycles of reduced ovarian respon siveness to GnRH agonist and recombinant hFSH and is not predicted by maximal se rum E2 or number of oocytes retrieved.

关键词：体外受精卵泡刺激素卵泡液取卵成熟卵泡促性腺激素免疫活性激动剂敏感期甾体激素

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IdH1 and IdH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors： a report of the European Organization for Research and Treat- ment of Cancer Brain Tumor Group

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中国神经肿瘤杂志 2010年第1期8卷 34-34页

作者： van den Bent M J dubbink HJ Marie Y Brandes AA Taphoorn MJ Wesseling P Frenay M Tijssen CC Lacombe d ldbaih A van Marion R Kros JM dinjens WN Gorlia T. Sanson M. dept Neuro-Oncology and Pathology Daniel den Hoed Cancer Center and Erasmus University Medical Center Rotterdam Rotterdam the Netherlands

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