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Comparisons and optimization of two absorption chiller types by considering heat transfer area, exergy and economy as single-objective functions

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CLEAN ENERGY 2024年第1期8卷 55-65页

作者： Qiu, Yida Wang, Jingkun Han, Jing Chen, Yuzhu Wang, Jun Lund, Peter d. Univ Liverpool Management Sch Liverpool L693BX Lancs England Power China Huadong Engn Corp Ltd 201 Gaojiao Rd Hangzhou 311122 Peoples R China Southeast Univ Key Lab Solar Energy Sci & Technol Jiangsu Prov 2 Si Pai Lou Nanjing 210096 Peoples R China Aalto Univ Sch Sci POB 15100 FI-00076 Espoo Finland

Absorption cooling technology is an environmentally friendly method to generate continuous chilled water making use of multiple thermal sources, such as waste heat and renewable thermal energy. In this study, two absorption chillers (nominal capacity of 400 kW) with series and parallel connections are evaluated. To research the ideal configuration of chillers after thermodynamic analysis, the structures of the chillers are optimized using the particle swarm optimization algorithm by considering the heat transfer area (HTA), exergy efficiency and total annual cost as single-objective functions. The impact of temperature differences between external and internal flows, heat exchanger efficiencies and the solution allocation ratio is estimated. The optimized HTA, coefficient of performance, exergy efficiency and total annual cost are 149.0 m2, 1.56, 29.44% and $229 119 for the series-connected chiller, and 146.7 m2, 1.59, 31.45% and $234 562 for the parallel-connected type, respectively. Under the lowest HTA condition, compared with the reference simulation results, the energy and exergy performances are improved, while the annual total cost is higher. The annual total cost is highest when maximizing the exergy efficiency, which is attributed to the increase in the HTA. The operating cost accounts for 27.42% (series type) and 26.54% (parallel type) when the annual cost is the lowest. Two absorption chillers with series and parallel connections are evaluated using a thermodynamic analysis. The chiller structures are optimized using the particle swarm optimization algorithm by considering the heat transfer area, exergy efficiency and total annual cost as single-objective functions. Graphical Abstract

关键词： absorption chiller series/parallel-connected temperature difference parameters solution allocation ratio REFRIGERATION SYSTEMS COOLING SYSTEM MULTIOBJECTIVE OPTIMIZATION PERFORMANCE ANALYSIS CLIMATE ZONES SERIES PARALLEL ENERGY CONSUMPTION REdUCE

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Hepatocellular carcinoma-the role of the underlying liver disease in clinical practice

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World Journal of Gastroenterology 2024年第19期30卷 2488-2495页

作者： Angelo Zambam de Mattos Isadora Zanotelli Bombassaro Arndt Vogel Jose d debes department of Internal Medicine Universidade Federal de Ciências da Saúde de Porto AlegreRSPorto Alegre 90020090Brazil Graduate Program in Medicine:Hepatology Federal University of Health Sciences of Porto AlegreRSPorto Alegre 90050-170Brazil division of Gastroenterology Hepatology University of TorontoHannover M5R 0A3Canada department of Medicine University of MinnesotaMinneapolisMN 55455United States

Hepatocellular carcinoma(HCC)is one of the most common causes of cancerrelated *** particular type of cancer has the distinctive characteristic of mostly happening in individuals with an underlying liver *** makes the management of patients more challenging,since physicians must take into consideration two different conditions,the chronic liver disease and the *** underlying liver disease has several implications in clinical practice,because different kinds of chronic liver disease can lead to varying degrees of risk of developing HCC,obstacles in surveillance,and differences in the efficacy of the treatment against HCC.A shift in the prevalence of liver diseases has been evident over the last few years,with viral hepatitis gradually losing the leading position as cause of HCC and metabolic dysfunction-associated steatotic liver disease gaining ***,in an era of personalized medicine,it is imperative that physicians are aware of the underlying liver disease of individuals with HCC and its impact in the management of their tumors.

关键词： Hepatocellular carcinoma Etiology Epidemiology Surveillance Therapy

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Malargüe Site Remediation: A Successful Solution for Uranium Mill Tailings

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原子能科学技术 2024年

作者： BARARI E díAZ J G GIOMIA KEMPF R A National Atomic Energy Commission Av.Del Libertador 8250 Ciudad Autónoma de Buenos AiresC1429BNP Argentina

Comisión Nacional de Energía Atómica(CNEA) has the responsibility for restoring uranium mining facilities once the operations have finished. CNEA, within its Environmental Program and in compliance with its legal responsibilities, decides to implement a restoration project for all sites related to the mining and processing of uranium ores. The Malargüe Site is located within the Province of Mendoza in the city of Malargüe. It is the first site to successfully complete its remediation. The activities consist of relocation of tailings to an engineering repository. The tailings management(encapsulation) and rehabilitation of the area was finished in June 2017. The remediation alternative for the ore tailings was selected after conducting comparative studies and submitted the project to the society for consideration. The objective of the encapsulation of the mineral tails is to isolate them from the environment, also proceeding with the decontamination and rehabilitation of the area(landscaping,post-closure monitoring and 20 years monitoring period). Encapsulation consisted of the construction of a containment cell for the mine tailings, to isolate them and prevent pollutants from entering the environment through the transfer routes. To clean the impacted areas, the soil was removed, it was incorporated into the encapsulation, and the filling was carried out with natural soils from the *** prevents radon transfer to the environment, as 222Ra is an alpha emitter with a half-life of four days, which produces its own radioactive progeny. Radon progeny are solids, and when a 222Ra nucleus emits an alpha particle into the air, the resulting 218Po nucleus, momentarily electrically charged, adheres to any dust particle. Remediation prevents the discharge into the air containing radon and also containing dust particles charged with intensely radioactive radon progeny. The tasks mentioned make it possible to decrease radon emanation, reduce radiological risks to the

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ACC for generalized log canonical thresholds for complex analytic spaces

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Science China Mathematics 2024年

作者： Christopher d.Hacon Lingyao Xie University of Utah department of Mathematics

We show that generalized log canonical thresholds for complex analytic spaces satisfy the ACC(ascending chain condition) and we characterize the accumulation points.

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Reference gene panel for urinary exosome-based molecular diagnostics in patients with kidney disease

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World Journal of Nephrology 2024年第3期13卷 62-72页

作者： deendayal d Mishra Pramod K Maurya Swasti Tiwari department of Molecular Medicine and Biotechnology Sanjay Gandhi Postgraduate Institute of Medical SciencesLucknow 226014Uttar PradeshIndia

BACKGROUNd Kidney disease is a severe complication of diabetes that often leads to end-stage renal *** diagnosis is crucial for prevention or ***,the current diagnostic methods,with their limitations in detecting the disease in its early stages,underscore the urgency and importance of finding new *** encapsulated inside urinary exosomes(UEs)have potential as early biomarkers for kidney *** need for reference miRNAs for accurate interpretation currently limits their translational *** To identify consistently expressing reference miRNAs from UEs of controls and patients with type 2 diabetesmellitus(T2dM)and biopsy-confirmed kidney *** miRNA profiling was performed on UEs from 31 human urine samples using a rigorous and unbiased *** UEs were isolated from urine samples collected from healthy individuals(n=6),patients with T2dM(n=13),and T2dM patients who also had kidney diseases(including diabetic nephropathy,n=5;membranous nephropathy,n=5;and IgA nephropathy,n=2)through differential *** characterizing the UEs,miRNA expression profiling using microarray technology was *** Microarray data analysis identified 14 miRNAs that were consistently expressed in UEs from 31 human samples,representing various kidney conditions:diabetic controls,diabetic nephropathy,membrane nephropathy,IgA nephropathy,and healthy *** in silico analysis,we determined that 10 of these miRNAs had significant potential to serve as reference genes in *** We identified uniformly expressing UE miRNAs that could serve as reference genes kidney disease biomarkers.

关键词： miRNA Microarray Urinary exosomes diabetic nephropathy Type 2 diabetes mellitus Kidney disease

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Understanding the spectrum of non-motor symptoms in multiple sclerosis:insights from animal models

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Neural Regeneration Research 2024年第1期19卷 84-91页

作者： Poornima d.E.Weerasinghe-Mudiyanselage Joong-Sun Kim Taekyun Shin Changjong Moon department of Veterinary Anatomy and Animal Behavior College of Veterinary Medicine and BK21 FOUR programChonnam National UniversityGwangjuRepublic of Korea department of Veterinary Anatomy College of Veterinary Medicine and Veterinary Medical Research InstituteJeju National UniversityJejuRepublic of Korea

Multiple sclerosis is a chronic autoimmune disease of the central nervous system and is generally considered to be a non-traumatic,physically debilitating neurological *** addition to experiencing motor disability,patients with multiple sclerosis also experience a variety of nonmotor symptoms,including cognitive deficits,anxiety,depression,sensory impairments,and ***,the pathogenesis and treatment of such non-motor symptoms in multiple scle rosis are still under *** studies for multiple sclerosis benefit from the use of disease-appropriate animal models,including experimental autoimmune *** to understanding the pathophysiology and developing treatments for non-motor symptoms,it is critical to chara cterize the animal model in terms of its ability to replicate certain non-motor features of multiple *** such,no single animal model can mimic the entire spectrum of *** review focuses on the non-motor symptoms that have been investigated in animal models of multiple sclerosis as well as possible underlying ***,we highlighted gaps in the literature to explain the nonmotor aspects of multiple sclerosis in expe rimental animal models,which will serve as the basis for future studies.

关键词： anxiety cognitive deficit depression experimental autoimmune encephalomyelitis motor disability neurological disorder pain pathophysiology preclinical study sensory impairments

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Anti-amyloid antibodies in Alzheimer’s disease: what did clinical trials teach us?

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Neural Regeneration Research 2025年第4期20卷 1092-1093页

作者： danko Jeremic Lydia Jiménez-díaz Juan d.Navarro-López NeuroPhysiology&Behavior Lab University of Castilla-La ManchaBiomedical Research Center(CRIB)School of Medicine of Ciudad RealCiudad RealSpain

Although many causes of Alzheimer’s disease(Ad)may exist,both the original amyloid cascade and tau hypotheses posit that abnormal misfolding and accumulation of amyloid-β(Aβ)and tau protein is the central event causing the ***,that conclusion could be only partly true,and there is conflicting evidence about the role of both proteins in Ad,being able to precede and influence one *** researchers argue that these proteins are mere executors rather than primary causes of ***,there have been continuing refinements of both hypotheses,with alternative explanations proposed.Aβand tau proteins may be independently involved in specific neurotoxic pathways;yet there may be other crucial processes going on in early ***,accumulating evidence suggests that Aβand tau act synergistically,rather than additively in disease onset(Jeremic et al.,2021,2023a).

关键词： amyloid Alzheimer additive

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Competitive interactions and coexistence of sympatric flagship carnivores in Asia

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Integrative Zoology 2024年第2期19卷 183-199页

作者： Zhilin LI Jiayu LU Xiaoyi SHI Li’an dUO James L.d.SMITH Tianming WANG Tianjin Key Laboratory of Conservation and Utilization of Animal diversity College of Life SciencesTianjin Normal UniversityTianjinChina department of Fisheries Wildlife and Conservation BiologyUniversity of MinnesotaSt.PaulMinnesotaUSA Ministry of Education Key Laboratory for Biodiversity Science and Engineering College of Life SciencesBeijing Normal UniversityBeijingChina National Forestry and Grassland Administration Key Laboratory for Conservation Ecology of Northeast Tiger and Leopard BeijingChina

Understanding the competition and coexistence of flagship carnivores is key to creating strategies for their conservation in the face of global carnivore *** studies exploring the dynamics and competition between tigers(Panthera tigris)and leopards(***)span decades,there is a lack of understanding regarding the factors that influence their coexistence mechanisms on a broad scale,as well as the drivers determining their exploitative and interference *** gathered a comprehensive list of research papers among which 36 papers explored the interspecific interactions between tigers and leopards and tested the influence of biotic and abiotic factors on the coexistence mechanisms along three dimensions using multiple response variables regression models;we also tested the influence of ecological drivers determining the exploitative or interference competition between tigers and *** and ungulate density were the most important predictors in regulating the coexistence *** and leopards exhibited more positive relations/higher overlaps as elevation increased in the spatial *** addition,they showed a higher dietary overlap in the prey-rich *** determined that interference competition between tigers and leopards was less frequently observed in habitats with dense tree cover and homogeneous vegetation ***,studies with multiple metrics would promote the detection of interference *** study provides new insight into the competitive interactions and coexistence mechanisms of tigers and leopards on a broad ***-makers and managers should pay more attention to the factors of elevation,prey abundance,and habitat structures for the conservation of tigers and leopards.

关键词： carnivores coexistence mechanisms competitive interactions exploitative competition interference competition

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Consensus-based distributed Particle Filters in Sensor Networks

Consensus-based Distributed Particle Filters in Sensor Netwo...

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2009中国控制与决策会议

作者： Nargess Sadeghzadeh.N Ahmad.afshar department of Electrical Engineering Amirkabir University of TechnologyTehranIran

ISBN: (纸本)9781424427239

＜正＞This paper considers the problem of distributed particle filtering using consensus *** monitored environment may possess nonlinear dynamics,nonlinear measurements,and non-Gaussian process and observation *** considers the scenario in which a set of sensor nodes make multiple,noisy measurements of the monitored system.-The goal of the proposed approach is to perform an on-line,distributed estimation of the current state at multiple sensor *** this new proposed algorithm,average consensus filters are well organized to do distributed computation and information consensus in distributed particle ***,sensors’ energy consumption concerns are considered partially *** order to achieve almost full environment information,sensors are assumed to have different sensing models,but same *** a case study,the application of the proposed algorithm to state estimation of an unmanned air vehicle is considered *** results show the good efficiency of the algorithm in the nonlinear state estimation.

关键词： Sensor Networks distributed State Estimation Consensus Algorithm Particle Filtering

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Chemical-assisted MMP reduction on methane-oil systems:Implications for natural gas injection to enhanced oil recovery

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Petroleum 2024年第1期10卷 101-108页

作者： Mohamed Almobarak Matthew B.Myers Colin d.Wood Yongbing Liu Ali Saeedi Quan Xie discipline of Petroleum Engineering WA School of Mines: Minerals Energy and Chemical Engineering Curtin University Commonwealth Scientific and Industrial Research Organization Curtin University Oil and Gas Innovation Centre Management State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation

Miscible natural gas injection is widely considered as a practical and efficient enhanced oil recovery technique. However, the main challenge in this process is the high minimum miscibility pressure（MMP）between natural gas and crude oil, which limits its application and recovery factor, especially in hightemperature reservoirs. Therefore, we present a novel investigation to quantify the effect of chemicalassisted MMP reduction on the oil recovery factor. Firstly, we measured the interfacial tension（IFT） of the methane-oil system in the presence of chemical or CO2to calculate the MMP reduction at a constant temperature（373K） using the vanishing interfacial tension（VIT） method. Afterwards, we performed three coreflooding experiments to quantify the effect of MMP reduction on the oil recovery factor under different injection *** interfacial tension measurements show that adding a small fraction（1.5 wt%） of the tested surfactant（SOLOTERRA ME-6） achieved 9% of MMP reduction, while adding 20 wt% of CO2to the methane yields 13% of MMP reduction. Then, the coreflooding results highlight the significance of achieving miscibility during gas injection, as the ultimate recovery factor increased from 65.5% under immiscible conditions to 77.2% using chemical-assisted methane, and to 79% using gas mixture after achieving near miscible condition. The results demonstrate the promising potential of the MMP reduction to significantly increase the oil recovery factor during gas injection. Furthermore, these results will likely expand the application envelop of the miscible gas injection, in addition to the environmental benefits of utilizing the produced gas by re-injection/recycling instead of flaring which contributes to reducing the greenhouse gas emissions.

关键词： Gas injection Enhanced oil recovery Miscibility Coreflooding

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